KEGG   PATHWAY: ccan00531
Entry
ccan00531                   Pathway                                
Name
Glycosaminoglycan degradation - Castor canadensis (American beaver)
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
ccan00531  Glycosaminoglycan degradation
ccan00531

Module
ccan_M00076  Dermatan sulfate degradation [PATH:ccan00531]
ccan_M00077  Chondroitin sulfate degradation [PATH:ccan00531]
ccan_M00078  Heparan sulfate degradation [PATH:ccan00531]
ccan_M00079  Keratan sulfate degradation [PATH:ccan00531]
Other DBs
GO: 0006027
Organism
Castor canadensis (American beaver) [GN:ccan]
Gene
109675293  Arsb; arylsulfatase B [KO:K01135] [EC:3.1.6.12]
109681133  [KO:K01197] [EC:3.2.1.35]
109681134  [KO:K01197] [EC:3.2.1.35]
109682634  [KO:K01137] [EC:3.1.6.14]
109683307  Hpse; heparanase isoform X1 [KO:K07964] [EC:3.2.1.166]
109686164  Hexa; beta-hexosaminidase subunit alpha [KO:K12373] [EC:3.2.1.52]
109687328  Naglu; LOW QUALITY PROTEIN: alpha-N-acetylglucosaminidase [KO:K01205] [EC:3.2.1.50]
109688981  [KO:K01195] [EC:3.2.1.31]
109689473  Gns; N-acetylglucosamine-6-sulfatase [KO:K01137] [EC:3.1.6.14]
109689941  Sgsh; N-sulphoglucosamine sulphohydrolase [KO:K01565] [EC:3.10.1.1]
109690641  [KO:K10532] [EC:2.3.1.78]
109690642  [KO:K10532] [EC:2.3.1.78]
109692745  Galns; N-acetylgalactosamine-6-sulfatase isoform X1 [KO:K01132] [EC:3.1.6.4]
109693216  Hyal2; hyaluronidase-2 [KO:K01197] [EC:3.2.1.35]
109693223  Hyal1; hyaluronidase-1 [KO:K01197] [EC:3.2.1.35]
109693227  Hyal3; hyaluronidase-3 isoform X1 [KO:K01197] [EC:3.2.1.35]
109693698  Glb1; beta-galactosidase isoform X1 [KO:K12309] [EC:3.2.1.23]
109695031  Ids; iduronate 2-sulfatase isoform X1 [KO:K01136] [EC:3.1.6.13]
109696115  Hexb; beta-hexosaminidase subunit beta [KO:K12373] [EC:3.2.1.52]
109698229  Idua; LOW QUALITY PROTEIN: alpha-L-iduronidase [KO:K01217] [EC:3.2.1.76]
109699884  Hpse2; LOW QUALITY PROTEIN: inactive heparanase-2 [KO:K07965] [EC:3.2.1.-]
109702494  [KO:K01197] [EC:3.2.1.35]
109702496  [KO:K01197] [EC:3.2.1.35]
Compound
C00426  Dermatan sulfate
C00573  Keratan sulfate
C00634  Chondroitin 4-sulfate
C00925  Heparan sulfate
G00526  
G00711  
G00872  DWA-2
G01391  
G01945  
G01977  
G02632  
G09660  
G10008  
G10505  Hyaluronic acid
G12336  
G13034  
G13035  
G13036  
G13037  
G13038  
G13039  
G13040  
G13041  
G13042  
G13043  
G13073  
G13074  
Reference
PMID:27570
  Authors
Greiling H, Stuhlsatz HW, Cantz M, Gehler J
  Title
Increased urinary excretion of keratan sulfate in fucosidosis.
  Journal
J Clin Chem Clin Biochem 16:329-34 (1978)
DOI:10.1515/cclm.1978.16.6.329
Reference
PMID:3161730
  Authors
Fuchs W, Beck M, Kresse H
  Title
Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate.
  Journal
Eur J Biochem 151:551-6 (1985)
DOI:10.1111/j.1432-1033.1985.tb09138.x
Related
pathway
ccan00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
ccan00533  Glycosaminoglycan biosynthesis - keratan sulfate
ccan00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
KO pathway
ko00531   

DBGET integrated database retrieval system