Castor canadensis (American beaver): 109675517 Help Entry 109675517         CDS       T04791                                  Symbol Irs4 Name (RefSeq) insulin receptor substrate 4   KO K17446   insulin receptor substrate 4 Organism ccan  Castor canadensis (American beaver) Pathway ccan04022   cGMP-PKG signaling pathway ccan04068   FoxO signaling pathway ccan04081   Hormone signaling ccan04140   Autophagy - animal ccan04152   AMPK signaling pathway ccan04211   Longevity regulating pathway ccan04213   Longevity regulating pathway - multiple species ccan04910   Insulin signaling pathway ccan04920   Adipocytokine signaling pathway ccan04923   Regulation of lipolysis in adipocytes ccan04930   Type II diabetes mellitus ccan04935   Growth hormone synthesis, secretion and action ccan05010   Alzheimer disease Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     109675517 (Irs4)    04022 cGMP-PKG signaling pathway     109675517 (Irs4)    04152 AMPK signaling pathway     109675517 (Irs4)   09133 Signaling molecules and interaction    04081 Hormone signaling     109675517 (Irs4)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     109675517 (Irs4)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     109675517 (Irs4)    04923 Regulation of lipolysis in adipocytes     109675517 (Irs4)    04920 Adipocytokine signaling pathway     109675517 (Irs4)    04935 Growth hormone synthesis, secretion and action     109675517 (Irs4)   09149 Aging    04211 Longevity regulating pathway     109675517 (Irs4)    04213 Longevity regulating pathway - multiple species     109675517 (Irs4)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     109675517 (Irs4)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     109675517 (Irs4) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IRS PH_8 PH Motif Other DBs NCBI-GeneID:  109675517 NCBI-ProteinID:  XP_020007795 UniProt:  A0A8C0ZLT3 LinkDB All DBs Position Unknown AA seq 1270 aa AA seqDB search MASCSFARDQATRRLRAAAAAAAAALTAVATTPLLSSGTPTALIGTGSSCPGAMWLSTAT GSRSDSESEEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRH SVRAAAAAAAAAASGAAVPALIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMV AENESEQESWYLLLSRLILESKRRRCGTLSAQPDGEPAALAAAAAAEPPFYKDVWQVVVK PRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRST VIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRH LGLLPLEPGGWLRRSRFEQFCQLRAIGDGEDEMLVTRRLITPSEPVPPSSRGRPHLPRAR RSRRAVSVPASFFRRLASSPVRDPHPEEAPNDRACEASGSASGNSGGKGNRQGKDDGQEG SEGDYMPMNNWGSGNGRGSGGGQGSSGQGSSSQSSGGNQCSGGRQESGGGQGSSGGQGSG GQGSGGNQCSGDGQGTAGGHGSGGGQGPGGGHGSGGGQEPRDGHGSGGGKNSGGAKGSGS GKSSDGDGDRGKSLKKRSYFGKLTQSKQQQMLPPPPPPPPPPAGATGGKGKSGGRFRLYF CADKGATKERKEPKEVRNTETPEGATRGLYRPRAFDEDEDDPYVPMRPGVAAPLASSSDY MPMAPQNDSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDPNKEDDSKDNDSDS DYMFMAPGAGAIPKNPKNPQGGSSSKSWSSYFSLPNPFQSSPLGQGDHSEYVPMLPGKFL GKGLDKETSSNGGPKDAATKPSAEGSVSKPGDGESPSKPSDDGPPKNKAKRPNRLSFIIK GNKIKPKPQKPTREQKEADSSNNYVNIDFTKRESNLPNPSAQGLPHSWGIIAGPRRSAFS NYLNVEFGAPFPNRLSDLLRAIPGANLFCLDGARWPHPPLPPNAPGSNANVEEGDYIEVM FNPAMTPAVPFADSAIRYDAETDRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEAQ ERRRPPSHSQSFFAVARAAVSAFPTDSLERDLSAASASAAALAAAPSLAVGRALAAASAL AAAPGIGAAAAGFEAAAGFDSASARWFQPVANAADAQAASRAQDVAGGSNPGAPNPAADL AGGENAAGGAAAAAPTLPPRPLRVPRPPERADSENNHDENDNDDIYVRMDFARPDNNKFD SPKRGWSFLN NT seq 3813 nt NT seq  +upstreamnt  +downstreamnt atggcgagttgctcctttgctcgcgaccaagcgacaaggagactgagagctgcagcagcg gcagcagcggcagctctaacagcggtggcgaccaccccacttctttcctcgggaaccccg accgcactcattgggaccgggtcgtcttgtccgggagccatgtggctctccacggccacg ggctcccggtcagactccgagtccgaggaggaagacctccccgtcggcgacgaagtctgc aaacgcggctacctgcggaaacagaaacatgggcacaggcgttacttcgtgctcaaactc gagaccgccgacgccccagctcggctggaatactacgaaaatgccaggaagttccggcac agtgtccgcgccgcggcggctgcagcagcggccgccgcctcgggtgccgcggtccccgcg ctcatcccaccacggcgcgtgatcaccctgtaccagtgcttctccgtgagccagcgagct gatgcaaggtaccgacacctcattgcccttttcacccaggacgagtacttcgcgatggtg gccgagaacgagtcggagcaagaaagctggtacttgctgctcagccgcctcatcctcgag agcaagcgccgccgctgcggcacgctcagcgcgcagccggacggagagccagccgcgctg gcggcggcagcggcggcggagccacccttctataaagatgtgtggcaggtagtagtgaaa cccagggggctggggcacagaaaagagctgagcggcgtgttccggctgtgtcttaccgac gaagaggtcgtgtttgtgaggctgaataccgaagtggccagcgtggtcgtccagctcctg agcatccgtcgctgcggtcactcggagcagtatttcttcttggaagtcggcagatccacc gtcatcggtccaggggagctgtggatgcaggtcgatgactgtgtggtggcccaaaacatg cacgagctgtttttggagaagatgagagctttgtgcgcagacgaatacagagcccgctgc cgcagctacagcatcagtattggcgcccacctgttaaccctgctgtccgctaggaggcac ctgggcttgctgccgctggagcccggcggctggctccgaaggtcccgctttgagcagttt tgccagctccgggccattggtgacggggaagacgagatgctcgttaccaggcgcctcata acacccagcgagcctgtgcctccctccagtcgaggacggccgcacctgcccagagcgcgc aggtccaggagagcggtttcagtgccagccagcttttttcgccgcttagcgtccagcccg gtacgtgacccgcaccctgaagaagcccccaacgatcgagcttgtgaagcctcaggctct gcctctggcaactctggggggaaaggcaatcgtcaaggcaaagatgatggtcaggaagga agcgaaggcgactacatgcccatgaacaattggggatcaggaaatggccggggttcagga ggtggtcagggctcaagtggtcaaggctccagtagccagagctcaggaggaaaccagtgt tctggagggaggcaggaatctggaggtggccagggctcaagtggcggccagggctcaggt ggacagggctccggaggaaaccagtgctcaggagatggccaaggtactgcaggtggccac ggctctggcggtggccagggacctggaggtggccacggctcaggcggtggccaggaacca agagatggccatggctcaggtggtggcaagaactctggaggggccaagggctcgggaagt gggaaaagctctgatggtgatggtgaccgtggaaaatctctgaagaaaaggtcctacttt ggcaagttaactcaaagcaagcaacagcaaatgctgcctccaccgcccccacctccaccc ccaccagctggagcaactggtggaaaagggaagtctggaggaagattccgactttatttt tgtgctgataaaggagccacaaaagaacgcaaagaacccaaagaagtgagaaacacagag accccagaaggtgcaacccggggtctctacagacccagagcttttgacgaagatgaggat gacccatatgtcccaatgaggccaggggtagctgcccctcttgcaagctctagtgattat atgccaatggctccccaaaatgactcggcttcaaaaaagcgccactctcgatcacctttt gaagattcaagaggctatatgatgatgtttcccagagtgagtccaccaccggccccaagt cctccaaaagcacctgatcctaataaagaggatgactcaaaggacaatgacagtgacagt gactatatgtttatggctcccggagcaggtgcaattccaaaaaaccctaagaatcctcag ggcggttcttcctctaaaagttggagctcctacttctctctgccaaatccttttcagagc tcacccttgggacagggtgaccacagtgagtatgtcccaatgctacctggaaagttcttg gggaagggcctagacaaagaaacctcttccaatgggggccccaaagatgcagctacaaag ccttcagctgaagggtcagtctcaaagcctggagatggggagtcaccttcaaagccttca gatgatgggcccccaaagaataaggcgaagagacctaaccgactttcttttattataaaa ggaaataaaatcaagcccaaaccacaaaagcccacacgtgagcagaaagaagctgacagc tccaacaactacgtcaacattgacttcactaaaagagagagcaatttgccaaacccctct gctcaaggactgccacattcgtggggcataattgctggtcccagacgctccgctttttct aattacctgaatgttgaattcggagcgccatttccaaaccgcctctcagatcttttaaga gctatcccaggtgccaacctcttctgtctggatggtgctaggtggccacatccccccctt cctcccaatgccccaggtagcaatgctaatgtggaagagggtgactacattgaagtaatg ttcaacccagcaatgacaccagccgtgccttttgctgacagtgccattcgctatgatgct gaaacagatcgaatctacgtggtcgaccccttttctgagtgctgtatggacatttctctc tcccctagccgatgctctgaaccaccacctgtagctaggctgctgcaggaggaagcgcaa gagagaagacgcccaccaagccattcgcaaagtttctttgcagttgccagagcggctgtc tcggcttttccaactgacagcctggagagagacctttcggcagcctccgcctcggctgct gctctggcagcggcgccatccctagcggtgggtcgggcgttagccgcggcctcggcgctc gctgctgctccgggcatcggcgcagccgccgcgggcttcgaggccgccgctggctttgac tccgcctccgcccgctggttccaacctgttgctaacgctgctgatgcccaggcagccagc cgggcccaggacgttgccgggggctccaatcctggagccccgaatccagctgcagacctt gcgggaggcgagaatgcggcgggcggggctgccgctgcagctcccaccctgccacctcgc cccctcagggtgccgagacccccagagagagcagattctgagaacaaccatgatgagaac gacaacgacgacatttacgtgagaatggactttgcgagacctgacaacaataaattcgac tctccgaaaagaggttggtcatttttgaattaa

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