KEGG   Castor canadensis (American beaver): 109681589
Entry
109681589         CDS       T04791                                 
Symbol
Grb2
Name
(RefSeq) growth factor receptor-bound protein 2 isoform X1
  KO
K04364  growth factor receptor-bound protein 2
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan01521  EGFR tyrosine kinase inhibitor resistance
ccan01522  Endocrine resistance
ccan04010  MAPK signaling pathway
ccan04012  ErbB signaling pathway
ccan04014  Ras signaling pathway
ccan04062  Chemokine signaling pathway
ccan04068  FoxO signaling pathway
ccan04072  Phospholipase D signaling pathway
ccan04150  mTOR signaling pathway
ccan04151  PI3K-Akt signaling pathway
ccan04380  Osteoclast differentiation
ccan04510  Focal adhesion
ccan04517  IgSF CAM signaling
ccan04540  Gap junction
ccan04550  Signaling pathways regulating pluripotency of stem cells
ccan04630  JAK-STAT signaling pathway
ccan04650  Natural killer cell mediated cytotoxicity
ccan04660  T cell receptor signaling pathway
ccan04662  B cell receptor signaling pathway
ccan04664  Fc epsilon RI signaling pathway
ccan04714  Thermogenesis
ccan04722  Neurotrophin signaling pathway
ccan04910  Insulin signaling pathway
ccan04912  GnRH signaling pathway
ccan04915  Estrogen signaling pathway
ccan04917  Prolactin signaling pathway
ccan04926  Relaxin signaling pathway
ccan04935  Growth hormone synthesis, secretion and action
ccan05034  Alcoholism
ccan05160  Hepatitis C
ccan05161  Hepatitis B
ccan05163  Human cytomegalovirus infection
ccan05165  Human papillomavirus infection
ccan05200  Pathways in cancer
ccan05203  Viral carcinogenesis
ccan05205  Proteoglycans in cancer
ccan05206  MicroRNAs in cancer
ccan05207  Chemical carcinogenesis - receptor activation
ccan05208  Chemical carcinogenesis - reactive oxygen species
ccan05210  Colorectal cancer
ccan05211  Renal cell carcinoma
ccan05213  Endometrial cancer
ccan05214  Glioma
ccan05215  Prostate cancer
ccan05220  Chronic myeloid leukemia
ccan05221  Acute myeloid leukemia
ccan05223  Non-small cell lung cancer
ccan05224  Breast cancer
ccan05225  Hepatocellular carcinoma
ccan05226  Gastric cancer
ccan05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109681589 (Grb2)
   04012 ErbB signaling pathway
    109681589 (Grb2)
   04014 Ras signaling pathway
    109681589 (Grb2)
   04630 JAK-STAT signaling pathway
    109681589 (Grb2)
   04068 FoxO signaling pathway
    109681589 (Grb2)
   04072 Phospholipase D signaling pathway
    109681589 (Grb2)
   04151 PI3K-Akt signaling pathway
    109681589 (Grb2)
   04150 mTOR signaling pathway
    109681589 (Grb2)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    109681589 (Grb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    109681589 (Grb2)
   04540 Gap junction
    109681589 (Grb2)
   04550 Signaling pathways regulating pluripotency of stem cells
    109681589 (Grb2)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    109681589 (Grb2)
   04660 T cell receptor signaling pathway
    109681589 (Grb2)
   04662 B cell receptor signaling pathway
    109681589 (Grb2)
   04664 Fc epsilon RI signaling pathway
    109681589 (Grb2)
   04062 Chemokine signaling pathway
    109681589 (Grb2)
  09152 Endocrine system
   04910 Insulin signaling pathway
    109681589 (Grb2)
   04912 GnRH signaling pathway
    109681589 (Grb2)
   04915 Estrogen signaling pathway
    109681589 (Grb2)
   04917 Prolactin signaling pathway
    109681589 (Grb2)
   04926 Relaxin signaling pathway
    109681589 (Grb2)
   04935 Growth hormone synthesis, secretion and action
    109681589 (Grb2)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    109681589 (Grb2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    109681589 (Grb2)
  09159 Environmental adaptation
   04714 Thermogenesis
    109681589 (Grb2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109681589 (Grb2)
   05206 MicroRNAs in cancer
    109681589 (Grb2)
   05205 Proteoglycans in cancer
    109681589 (Grb2)
   05207 Chemical carcinogenesis - receptor activation
    109681589 (Grb2)
   05208 Chemical carcinogenesis - reactive oxygen species
    109681589 (Grb2)
   05203 Viral carcinogenesis
    109681589 (Grb2)
   05231 Choline metabolism in cancer
    109681589 (Grb2)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109681589 (Grb2)
   05225 Hepatocellular carcinoma
    109681589 (Grb2)
   05226 Gastric cancer
    109681589 (Grb2)
   05214 Glioma
    109681589 (Grb2)
   05221 Acute myeloid leukemia
    109681589 (Grb2)
   05220 Chronic myeloid leukemia
    109681589 (Grb2)
   05211 Renal cell carcinoma
    109681589 (Grb2)
   05215 Prostate cancer
    109681589 (Grb2)
   05213 Endometrial cancer
    109681589 (Grb2)
   05224 Breast cancer
    109681589 (Grb2)
   05223 Non-small cell lung cancer
    109681589 (Grb2)
  09172 Infectious disease: viral
   05161 Hepatitis B
    109681589 (Grb2)
   05160 Hepatitis C
    109681589 (Grb2)
   05163 Human cytomegalovirus infection
    109681589 (Grb2)
   05165 Human papillomavirus infection
    109681589 (Grb2)
  09165 Substance dependence
   05034 Alcoholism
    109681589 (Grb2)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    109681589 (Grb2)
   01522 Endocrine resistance
    109681589 (Grb2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccan04131]
    109681589 (Grb2)
Membrane trafficking [BR:ccan04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Receptor tyrosine kinase (RTK) adaptor proteins
    109681589 (Grb2)
SSDB
Motif
Pfam: SH2 SH3_1 SH3_9 SH3_2 SH3_10 SH2_2 DUF5093 DUF7145
Other DBs
NCBI-GeneID: 109681589
NCBI-ProteinID: XP_020012007
UniProt: A0A8B7TYS0
LinkDB
Position
Unknown
AA seq 168 aa
MLTGLPSFLRWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFK
VLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIEQVPQQPTYVQALFDFDP
QEDGELGFRRGDFIHVMDNSDPNWWKGACHGQTGMFPRNYVTPVNRNV
NT seq 507 nt   +upstreamnt  +downstreamnt
atgttgactggcttgccttccttccttaggtggttttttggcaaaatccccagagccaag
gcagaagaaatgcttagcaaacagaggcatgatggggcctttctgatccgcgagagtgag
agtgcgcctggggatttttccctctctgtcaagtttggaaatgatgtgcagcacttcaag
gtgctccgtgatggagctggaaagtacttcctctgggtggtgaagttcaattctttgaac
gagctggtagattatcacagatcgacatctgtgtctaggaaccagcagatatttctgcgg
gatatagagcaggtgccacagcagccaacgtacgtccaggctctctttgactttgacccc
caggaggatggtgagctgggcttccgccggggagacttcatccacgtcatggataactca
gatcccaattggtggaagggggcttgccatgggcagaccggcatgtttccccgcaattat
gtcacccctgtgaaccggaacgtctaa

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