Castor canadensis (American beaver): 109681612
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Entry
109681612 CDS
T04791
Symbol
Hsd11b1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan00140
Steroid hormone biosynthesis
ccan00980
Metabolism of xenobiotics by cytochrome P450
ccan01100
Metabolic pathways
ccan05204
Chemical carcinogenesis - DNA adducts
Module
ccan_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
109681612 (Hsd11b1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
109681612 (Hsd11b1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
109681612 (Hsd11b1)
Enzymes [BR:
ccan01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
109681612 (Hsd11b1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
THF_DHG_CYH_C
2-Hacid_dh_C
Shikimate_DH
Motif
Other DBs
NCBI-GeneID:
109681612
NCBI-ProteinID:
XP_020012033
UniProt:
A0A8B7TWT9
LinkDB
All DBs
Position
Unknown
AA seq
181 aa
AA seq
DB search
MAFMKKYLLPILMLFLAYYYYSENEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAH
LVVTARSKEGLQKVVSRCLELGAASAHYIAGTMEDFSFTEQFVAKAGKLMGGLDMLILNH
ITNSSLTPFRDDIPLVRRNMEVNFLSYVALTVAALPMLKQSNGSIAVISSMAGECDRDQC
G
NT seq
545 nt
NT seq
+upstream
nt +downstream
nt
atggcttttatgaaaaaatatctgctccccattctgatgctcttcctggcctactactac
tattccgaaaatgaggagttcagaccagaaatgcttcaaggaaagaaagtgattgtcaca
ggggccagcaaagggattggaagagaaatggcttatcatctggcaaagatgggagcccat
ctggtggtgacagcaaggtcaaaagaaggtctacagaaggtagtatcccgctgcctggaa
cttggggcagcctcagcacactacattgctggcacgatggaagacttcagtttcacagag
caatttgttgccaaagcaggaaagctcatggggggactagacatgctcatcctcaaccac
atcaccaactcttctttgactccttttcgtgatgatatcccccttgtgcgcagaaacatg
gaagtcaacttcctcagttatgtggccctgactgtagctgccttgcccatgctgaagcaa
agcaatggaagcattgctgtcatctcctcgatggctggtgagtgtgacagggaccagtgt
ggaag
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