KEGG   Castor canadensis (American beaver): 109685632
Entry
109685632         CDS       T04791                                 
Symbol
Tgfb1
Name
(RefSeq) transforming growth factor beta-1
  KO
K13375  transforming growth factor beta-1
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan04010  MAPK signaling pathway
ccan04060  Cytokine-cytokine receptor interaction
ccan04068  FoxO signaling pathway
ccan04110  Cell cycle
ccan04148  Efferocytosis
ccan04218  Cellular senescence
ccan04350  TGF-beta signaling pathway
ccan04380  Osteoclast differentiation
ccan04390  Hippo signaling pathway
ccan04518  Integrin signaling
ccan04659  Th17 cell differentiation
ccan04672  Intestinal immune network for IgA production
ccan04926  Relaxin signaling pathway
ccan04932  Non-alcoholic fatty liver disease
ccan04933  AGE-RAGE signaling pathway in diabetic complications
ccan05140  Leishmaniasis
ccan05142  Chagas disease
ccan05144  Malaria
ccan05145  Toxoplasmosis
ccan05146  Amoebiasis
ccan05152  Tuberculosis
ccan05161  Hepatitis B
ccan05166  Human T-cell leukemia virus 1 infection
ccan05200  Pathways in cancer
ccan05205  Proteoglycans in cancer
ccan05210  Colorectal cancer
ccan05211  Renal cell carcinoma
ccan05212  Pancreatic cancer
ccan05220  Chronic myeloid leukemia
ccan05225  Hepatocellular carcinoma
ccan05226  Gastric cancer
ccan05321  Inflammatory bowel disease
ccan05323  Rheumatoid arthritis
ccan05410  Hypertrophic cardiomyopathy
ccan05414  Dilated cardiomyopathy
ccan05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    109685632 (Tgfb1)
   04350 TGF-beta signaling pathway
    109685632 (Tgfb1)
   04390 Hippo signaling pathway
    109685632 (Tgfb1)
   04068 FoxO signaling pathway
    109685632 (Tgfb1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    109685632 (Tgfb1)
   04518 Integrin signaling
    109685632 (Tgfb1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    109685632 (Tgfb1)
  09143 Cell growth and death
   04110 Cell cycle
    109685632 (Tgfb1)
   04218 Cellular senescence
    109685632 (Tgfb1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    109685632 (Tgfb1)
   04672 Intestinal immune network for IgA production
    109685632 (Tgfb1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    109685632 (Tgfb1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    109685632 (Tgfb1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109685632 (Tgfb1)
   05205 Proteoglycans in cancer
    109685632 (Tgfb1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    109685632 (Tgfb1)
   05212 Pancreatic cancer
    109685632 (Tgfb1)
   05225 Hepatocellular carcinoma
    109685632 (Tgfb1)
   05226 Gastric cancer
    109685632 (Tgfb1)
   05220 Chronic myeloid leukemia
    109685632 (Tgfb1)
   05211 Renal cell carcinoma
    109685632 (Tgfb1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    109685632 (Tgfb1)
   05161 Hepatitis B
    109685632 (Tgfb1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    109685632 (Tgfb1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    109685632 (Tgfb1)
   05144 Malaria
    109685632 (Tgfb1)
   05145 Toxoplasmosis
    109685632 (Tgfb1)
   05140 Leishmaniasis
    109685632 (Tgfb1)
   05142 Chagas disease
    109685632 (Tgfb1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    109685632 (Tgfb1)
   05321 Inflammatory bowel disease
    109685632 (Tgfb1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    109685632 (Tgfb1)
   05414 Dilated cardiomyopathy
    109685632 (Tgfb1)
   05415 Diabetic cardiomyopathy
    109685632 (Tgfb1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    109685632 (Tgfb1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    109685632 (Tgfb1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:ccan03110]
    109685632 (Tgfb1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ccan04052]
    109685632 (Tgfb1)
   00536 Glycosaminoglycan binding proteins [BR:ccan00536]
    109685632 (Tgfb1)
Chaperones and folding catalysts [BR:ccan03110]
 Intramolecular chaperones
  Others
   109685632 (Tgfb1)
Cytokines and neuropeptides [BR:ccan04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   109685632 (Tgfb1)
Glycosaminoglycan binding proteins [BR:ccan00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   109685632 (Tgfb1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 109685632
NCBI-ProteinID: XP_020018149
UniProt: A0A250YHB2
LinkDB
Position
Unknown
AA seq 390 aa
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQVDVPTGPLPDAVLALYNSTRDRVAGESADPEPEPEADYYAKEVTRVLMVETNNPI
YEKTKNIAHSIYMFFNTSELREAVPDPLLLSRAELRLQRLKSHVEQYVELYQKYSNNSWR
YLSNRKLTAISSPEWLSFDVTTVVRQWLSQGEVIEGFRFSAHCSCDNKDNILQVEINGIT
PKRRGDLGTIHDMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLYI
DFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASASPCCVPQA
LEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccgccctcggggctgcggctcctgccgctgctgctaccgctgctgtggctactagtg
ttgacgcctggccggccagctgcgggactgtccacctgcaagaccatcgatatggaactg
gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaaactaaggctcgcc
agccctccgagccaggtggacgtgcctaccggccctctgcccgacgccgtgctcgctttg
tacaacagcacccgcgaccgggtggcgggggagagcgccgacccggagcctgagcccgag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaccaacaacccaatc
tatgaaaaaactaagaacatcgcacatagcatatatatgttcttcaacacatcagaactg
cgggaagcggtgcctgaccccttgttgctgtcccgggcagagctgcgtctgcagaggctg
aagtcacatgtggagcaatatgtggaactgtaccagaaatacagcaacaattcctggcgc
tacctcagcaaccggaagctgaccgccattagttcgcctgagtggttgtcctttgatgtc
actaccgttgtgcggcagtggctgagccaaggagaggtaattgagggctttcgcttcagc
gcccactgctcttgtgacaataaagataacatactccaagtggaaatcaacgggatcact
cccaaacgccggggtgacctgggcaccattcatgacatgaaccggccgttcctgctcctc
atggctaccccgctggagagggcccaacatctgcatagctcccggcaccgccgagccctg
gacaccaactactgcttcagctccacggagaagaactgctgtgtgcggcagctgtacatt
gacttccgcaaggacctgggctggaagtggatccatgagcccaagggctaccacgccaac
ttctgcctggggccttgcccctacatttggagcctggacacgcagtacagcaaggtcctg
gccctgtacaaccagcacaacccgggcgcgtcggcgtcgccatgctgcgtgccgcaggca
ctggagccgctgcccatcgtgtactatgtaggccgcaagcccaaggtggagcagctgtct
aacatgatcgtgcgctcctgcaagtgcagctga

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