Castor canadensis (American beaver): 109685893
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Entry
109685893 CDS
T04791
Symbol
Itch
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan04120
Ubiquitin mediated proteolysis
ccan04144
Endocytosis
ccan04330
Notch signaling pathway
ccan04668
TNF signaling pathway
ccan04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
109685893 (Itch)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
109685893 (Itch)
04668 TNF signaling pathway
109685893 (Itch)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
109685893 (Itch)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
109685893 (Itch)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ccan04131
]
109685893 (Itch)
04121 Ubiquitin system [BR:
ccan04121
]
109685893 (Itch)
Enzymes [BR:
ccan01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
109685893 (Itch)
Membrane trafficking [BR:
ccan04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
109685893 (Itch)
Ubiquitin system [BR:
ccan04121
]
Ubiquitin ligases (E3)
HECT type E3
109685893 (Itch)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
PQQ_2
Motif
Other DBs
NCBI-GeneID:
109685893
NCBI-ProteinID:
XP_020018572
UniProt:
A0A8B7UH03
LinkDB
All DBs
Position
Unknown
AA seq
709 aa
AA seq
DB search
MSGAAGTSQNDDGSRPKDEARVSTNGSDDPEDTGSGENRKVNGNNSPSLSNGGFKPSRPP
RPSRPPPPTPRRPASVNGSPSATSESDGSSTGSLPPTSTTTNISEGATSGLIIPLTISGG
SGPRPLNPVTQAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRI
YYVDHFTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFATSQSKEF
DPLGPLPPGWEKRTDNNGRVYFVNHNTRITQWEDPRSQGQLNEKPLPEGWEMRFTVDGVP
YFVDHNRRTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFRFWCQQLTMPQHIKITVTR
KTLFEDSFQQIMSFNPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEY
AGKDNYCLQINPASYINPDHLKYFHFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGL
KDLESIDPEFYNSLIWVKENNIEECGLEMYFSVDKEILGEIKSHDLKPNGGNILVTEENK
EEYIRMVAEWRLSRGVEEQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQ
RHAIYRHYTRTSKQIMWFWQFVKEIDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKF
CIEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2130 nt
NT seq
+upstream
nt +downstream
nt
atgagtggggcggcaggtacttcacagaatgatgatggctctagacccaaggatgaagca
agagtgagcacaaatggatcagatgatcctgaggatacaggatctggtgaaaataggaag
gtcaatgggaacaattctccatcgctctcaaatggtggttttaagccctctagacctcca
agaccttcacggccacctccacccaccccacgtagaccagcatcggtcaatggttcacca
tctgccacttccgaaagtgatggatctagtacaggctctctaccaccaacaagtacaact
acaaatatatctgaaggagcaacatctggattaataattcctcttactatatctggaggc
tcagggcctaggccattaaatcctgtaactcaagctcccctaccacctggttgggagcag
agagtggaccagcatggacgagtttattatgtagatcatgttgaaaaaagaacaacatgg
gacagacctgaacctctgcctcctggctgggaacggcgggttgacaatatgggacgtatt
tattatgttgaccatttcacaagaacaacaacatggcagaggccaacattggaatccgtc
cgaaactatgaacagtggcagctacaacgtagtcaacttcaaggagcaatgcagcagttt
aaccagagattcatttatgggaatcaagatttgtttgctacatcacaaagtaaagaattt
gatccccttggtcctctgccacctggatgggagaagagaactgataacaatggcagagta
tattttgtcaaccacaacactcgaattacacaatgggaagaccccagaagtcaaggtcaa
ttaaatgaaaagcccttacctgaaggctgggaaatgagattcacagtagatggagttccg
tattttgttgaccacaacagaagaacaaccacctatatagatccccgcacaggaaaatct
gccttagacaatggaccacagatagcatatgttcgagacttcaaggcaaaagttcagtat
ttccggttttggtgtcagcaactgaccatgccacagcacataaagatcacagtgacaaga
aaaacattgtttgaggattcctttcaacagataatgagcttcaatccccaagacctgcga
agacgtttgtgggtgatttttccaggagaagaaggtttagattatggaggtgtagcaaga
gaatggttctttcttttgtcacatgaagtgttgaaccccatgtattgcctgtttgaatat
gcagggaaggacaactactgcttgcagataaaccctgcttcttacatcaatccagatcac
ttgaaatactttcattttattggcaggtttattgccatggctctgttccatgggaaattt
atagacaccggtttttctttaccattctataaacgtatcttgaacaaaccagttggactt
aaggatttagaatctattgatccagaattttacaattctctaatctgggttaaagaaaac
aatattgaggaatgtggtttggaaatgtacttctccgttgataaagaaattttaggtgaa
attaagagtcatgatttgaaacccaatggtggcaatattcttgtgacagaagaaaataaa
gaagaatacattagaatggtagctgagtggaggttatctagaggtgttgaagaacagaca
caagctttctttgaaggctttaatgaaattcttccccagcagtatttgcagtacttcgat
gcaaaggaattagaggtacttttatgtggaatgcaagagattgatttgaatgactggcaa
agacatgccatctaccgtcattatactaggacaagcaaacaaatcatgtggttttggcag
tttgttaaagaaattgataatgagaagagaatgagacttctacagtttgttactggaacc
tgccgattgccagtaggaggatttgctgacctcatggggagcaatggaccacagaaattc
tgcattgaaaaagttgggaaagaaaattggttacccaggagtcatacctgttttaaccgc
ctagaccttccaccttacaagagctatgagcaactgaaggaaaaactgttgtttgccatt
gaagaaacagaaggatttggacaagagtaa
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