Castor canadensis (American beaver): 109687320
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Entry
109687320 CDS
T04791
Symbol
Brca1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan01524
Platinum drug resistance
ccan03440
Homologous recombination
ccan03460
Fanconi anemia pathway
ccan04120
Ubiquitin mediated proteolysis
ccan04151
PI3K-Akt signaling pathway
ccan05206
MicroRNAs in cancer
ccan05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
109687320 (Brca1)
09124 Replication and repair
03440 Homologous recombination
109687320 (Brca1)
03460 Fanconi anemia pathway
109687320 (Brca1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
109687320 (Brca1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
109687320 (Brca1)
09162 Cancer: specific types
05224 Breast cancer
109687320 (Brca1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
109687320 (Brca1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
ccan01009
]
109687320 (Brca1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
ccan04121
]
109687320 (Brca1)
03036 Chromosome and associated proteins [BR:
ccan03036
]
109687320 (Brca1)
03400 DNA repair and recombination proteins [BR:
ccan03400
]
109687320 (Brca1)
Enzymes [BR:
ccan01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
109687320 (Brca1)
Protein phosphatases and associated proteins [BR:
ccan01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
109687320 (Brca1)
Ubiquitin system [BR:
ccan04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
109687320 (Brca1)
Multi subunit type E3
BRCC complex
109687320 (Brca1)
Chromosome and associated proteins [BR:
ccan03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
109687320 (Brca1)
DNA repair and recombination proteins [BR:
ccan03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
109687320 (Brca1)
BRCA1-A complex
109687320 (Brca1)
BRCA1-B complex
109687320 (Brca1)
BRCA1-C complex
109687320 (Brca1)
BRCA complex
109687320 (Brca1)
FA (Fanconi anemia) pathway
Downstream FA components
109687320 (Brca1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
BRCT
zf-C3HC4
zf-C3HC4_2
zf-RING_UBOX
zf-C3HC4_4
zf-RING_2
zf-C3HC4_3
zf-RING_5
RING_XB3-XBAT31
zf-RING_6
zf-Nse
zf-RING_10
zf-ANAPC11
RTT107_BRCT_5
zf-rbx1
Prok-RING_4
zf-RING_4
Motif
Other DBs
NCBI-GeneID:
109687320
NCBI-ProteinID:
XP_020020739
UniProt:
A0A8B7UPE4
LinkDB
All DBs
Position
Unknown
AA seq
715 aa
AA seq
DB search
MDLSADHIDEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQKKGPSR
CPLCKNDITKRSLQESTRFSQLVEELLKIIHAFELDTGLQFANNYNFSKKENNSPEHLKE
EVSIIQSMGYRNRAKRLRQSEPENPSMQETSLSVQLSNLGIMRSLRTKQQIQPRNKSVYI
ELGSDSSEDTVNKANYCSVTDQELLQITPEGARAEASLDSAKKGEVAPGYESETNLFEDC
SGLSSQSDILTTQQRDTMQDNLIKLQQEMAHLEAVLEQHESQPPDSSPSLIADSYDPDNL
LNPEQNISGKAVLTLEKSNEYPISQNPENLSANKFQVSPGPGVERSSPSKSQFGGNRWSA
HSHSGSLQDRSYPSQEEVVKILDSEEQKQEKNNPHDVMDQAYLPRQDLGGTPYLESGISL
FSSKLESDPPEDRAPEPAHVCSSPTSNSVLKSSQFQVAEFANGSAAAHTSNTAGYNTGEE
STSREKPELTSSTERVNKRISMVVSGLTPKEFMLAHKFARKYHITLTNVLTEETTHVVIK
TDTEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKMLDERDFEVKGDVVNGRNHQGPK
RARESQERKIFRGLEICCYGPFTNMPTDQLEWMLQLCGASVVKELSSFTLGTGAHPIVVV
QPDAWTEDDGFHAIGKVCEALVVTREWVLDSVALYQCQDLDTYLIPQIAHSRDCS
NT seq
2148 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgcagatcacattgacgaagtacaaaatgtccttaatgctatgcagaaa
atcttagagtgtccaatctgtctggaattgatcaaagaacctgtttccacgaagtgtgac
cacatattttgcaaattttgtatgctgaaacttctcaaccagaagaaagggccttcacgg
tgtcctttgtgtaagaatgatataaccaaaagaagtctacaagaaagtacaagatttagt
caacttgttgaagagctattgaaaatcattcatgcttttgagcttgacacaggattgcag
tttgcaaataattataacttttcaaaaaaggaaaataactctcctgaacatttaaaggag
gaggtttctatcatccaaagtatgggctaccgaaatcgtgccaaaagacttcggcagagt
gaaccagaaaatccttccatgcaggaaaccagtcttagtgtccaactctctaaccttgga
attatgagatctctgaggacaaagcagcagatacaacctcgtaataaatcagtctatatt
gaattgggatctgattcttctgaagatacagttaataaggcaaattattgcagtgtgaca
gaccaagaattgttacagatcacccctgaaggagccagggctgaagccagtttggattct
gcaaagaagggtgaagtggcacctgggtatgagagtgagacaaacctctttgaagactgc
tcagggctgtcctcacagagcgacattttaaccactcagcaaagggataccatgcaagat
aacttgataaagctccagcaggaaatggctcatctagaagctgtgctagagcaacatgag
agccagcctcctgacagctccccttccctcatagctgactcttacgaccctgacaacctg
ctaaatccagaacaaaacatatcaggaaaagcagttttaactttggagaaaagtaatgaa
tatcctataagccagaatccagaaaacctttctgctaacaaatttcaagtatctccagga
ccaggagtagaaagatcttccccttctaagtcccagttcggaggtaataggtggtctgca
cacagccactctgggagtcttcaggacagaagctacccatctcaagaggaggttgttaag
attcttgattcagaggagcaaaaacaggaaaagaataacccacatgatgtaatggaccag
gcttatttgccaaggcaagatctagggggaaccccatacctggaatctggaattagcctc
ttctctagtaaacttgaatctgacccccctgaagacagagctccagagccagctcatgtt
tgcagctcaccaacttcaaattctgtattgaaatcctcccaatttcaagttgcagaattt
gccaacggttcagctgctgctcatactagtaatactgctgggtataatacaggggaagaa
agtacaagtagagagaagccagaattgacgtcttcaacagaaagggtcaacaaaagaata
tccatggtggtatcaggcttgacccccaaagaattcatgcttgcacacaagtttgccaga
aaatatcacatcactttaactaatgtacttactgaagagactactcatgtcgttattaaa
acagatactgagtttgtgtgtgaacggacactgaaatattttctgggaattgcaggagga
aaatgggtagttagctatttctgggtaacccagtctattaaagaaagaaaaatgctagat
gagcgtgattttgaggtcaaaggagatgtggtcaatggaagaaatcaccaaggtccaaag
cgagcaagagagtcccaggagagaaagatcttcagaggcctagaaatctgttgctacggg
ccctttaccaacatgcccacagatcaactggagtggatgctgcagctgtgtggggcttct
gtcgtgaaggagctttcctcattcacccttggcacaggtgctcacccaattgtggtcgta
cagccagatgcctggacagaggacgatggcttccatgcaattgggaaggtgtgtgaggca
ctggtggtgacccgggagtgggttttggacagcgtagccctttaccagtgccaggatctg
gacacctacctgataccacagattgcccacagccgtgattgcagctag
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integrated database retrieval system
