Castor canadensis (American beaver): 109690752 Help Entry 109690752         CDS       T04791                                  Symbol Psen2 Name (RefSeq) presenilin-2 isoform X1   KO K04522   presenilin 2 [EC:3.4.23.-] Organism ccan  Castor canadensis (American beaver) Pathway ccan04330   Notch signaling pathway ccan04722   Neurotrophin signaling pathway ccan05010   Alzheimer disease ccan05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04330 Notch signaling pathway     109690752 (Psen2)  09150 Organismal Systems   09156 Nervous system    04722 Neurotrophin signaling pathway     109690752 (Psen2)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     109690752 (Psen2)    05022 Pathways of neurodegeneration - multiple diseases     109690752 (Psen2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:ccan01002]     109690752 (Psen2) Peptidases and inhibitors [BR:ccan01002]  Aspartic peptidases   Family A22: presenilin family    109690752 (Psen2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Presenilin DUF6541 Milton Motif Other DBs NCBI-GeneID:  109690752 NCBI-ProteinID:  XP_020025841 UniProt:  A0A250YIA3 LinkDB All DBs Position Unknown AA seq 447 aa AA seqDB search MLSFMASDSEEEVCDERTSLMSAESPTPRSCQEGRQVLEDRENAQWRSQESEEDCEEDPD QYVCSGVPGRPSGLEEQLALKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLIY TPFTEDTPSVGQRLLNSVLNTLTMIGVIVAMTIFLVVLYKHRCYKFIHGWLIMSSLMLLF LFTYIYLGEVLKTYNVAMDYPTLLLTVWNFGAVGMVSIHWKGPLVLQQAYLIMISALMAL VFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVWT VSMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEVFEPPLPGYPGEELEEEEERGVK LGLGDFIFYSVLVGKAAATGSGDWNTTLACFVAILIGLCLTLLLLAVFKKALPALPISIT FGLIFYFSTDNLVRPFMDTLASHQLYI NT seq 1344 nt NT seq  +upstreamnt  +downstreamnt atgctctcattcatggcctctgacagcgaggaagaagtgtgtgacgagcggacgtctctg atgtcggctgagagccccacaccccgctcctgtcaggagggcaggcaggttctggaggac agagagaatgcccagtggaggagccaggaaagcgaggaggactgtgaggaagaccctgac cagtacgtctgcagtggggtccccgggcggccatcaggcctggaggaacagctggccctg aagtacggggcgaagcacgtgattatgctcttcgtgcctgtcacgctgtgcatgatcgtg gtggtggccaccatcaaatccgtgcgcttctacacggagaagaatggacagctcatctac acacccttcacggaggacacgccttcagtgggccagcgcctcctcaactccgtgctgaac acacttaccatgatcggtgtaatcgtggccatgaccatcttcctggtggtgctgtacaag caccgctgctacaagtttatccacggctggttgatcatgtcctccttgatgctgctgttc ctgttcacctacatctacctcggggaagtactcaaaacctacaatgtggccatggactac cccacactcctgctgaccgtctggaactttggggcagtgggcatggtgagcatccactgg aaggggcctctggtgctgcagcaggcctacctcatcatgatcagcgcgctcatggctctg gtgttcatcaagtacctccctgagtggtcggcctgggttatcctgggtgccatctctgtg tacgatcttgtggctgtgctgtgtcccaaaggaccactgaggatgctggtggaaactgcc caggagagaaatgagcccatatttcctgccctgatatactcgtccgccatggtgtggaca gtgagcatggcaaagctagacccttcctcccagggagcactccagctcccctacgaccca gagatggaagaagactcctatgatagctttggggagccgtcataccctgaggtctttgag ccccccttgcctggctacccaggggaagagctggaggaagaggaagaaagaggtgtgaag ctaggcctgggagacttcatcttctacagcgtgctggtgggcaaggcagcggccacaggc agcggggactggaacaccacgctggcctgctttgttgccatcctcataggcttgtgtctg accctcctgctgcttgctgtgttcaagaaagcgctgcctgcccttcccatctccatcacc tttggcctcatcttctacttctccacagacaacctggtgcgtccgttcatggacacgctt gcctcccaccagctctacatctga

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