Castor canadensis (American beaver): 109693564 Help Entry 109693564         CDS       T04791                                  Symbol Traf6 Name (RefSeq) TNF receptor-associated factor 6   KO K03175   TNF receptor-associated factor 6 [EC:2.3.2.27] Organism ccan  Castor canadensis (American beaver) Pathway ccan04010   MAPK signaling pathway ccan04064   NF-kappa B signaling pathway ccan04120   Ubiquitin mediated proteolysis ccan04140   Autophagy - animal ccan04144   Endocytosis ccan04380   Osteoclast differentiation ccan04517   IgSF CAM signaling ccan04620   Toll-like receptor signaling pathway ccan04621   NOD-like receptor signaling pathway ccan04622   RIG-I-like receptor signaling pathway ccan04657   IL-17 signaling pathway ccan04722   Neurotrophin signaling pathway ccan04936   Alcoholic liver disease ccan05132   Salmonella infection ccan05133   Pertussis ccan05135   Yersinia infection ccan05140   Leishmaniasis ccan05142   Chagas disease ccan05145   Toxoplasmosis ccan05152   Tuberculosis ccan05160   Hepatitis C ccan05161   Hepatitis B ccan05162   Measles ccan05168   Herpes simplex virus 1 infection ccan05169   Epstein-Barr virus infection ccan05170   Human immunodeficiency virus 1 infection ccan05171   Coronavirus disease - COVID-19 ccan05200   Pathways in cancer ccan05222   Small cell lung cancer ccan05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ccan05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ccan00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     109693564 (Traf6)  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     109693564 (Traf6)    04064 NF-kappa B signaling pathway     109693564 (Traf6)   09133 Signaling molecules and interaction    04517 IgSF CAM signaling     109693564 (Traf6)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     109693564 (Traf6)    04140 Autophagy - animal     109693564 (Traf6)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     109693564 (Traf6)    04621 NOD-like receptor signaling pathway     109693564 (Traf6)    04622 RIG-I-like receptor signaling pathway     109693564 (Traf6)    04657 IL-17 signaling pathway     109693564 (Traf6)   09156 Nervous system    04722 Neurotrophin signaling pathway     109693564 (Traf6)   09158 Development and regeneration    04380 Osteoclast differentiation     109693564 (Traf6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     109693564 (Traf6)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     109693564 (Traf6)   09162 Cancer: specific types    05222 Small cell lung cancer     109693564 (Traf6)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     109693564 (Traf6)    05161 Hepatitis B     109693564 (Traf6)    05160 Hepatitis C     109693564 (Traf6)    05171 Coronavirus disease - COVID-19     109693564 (Traf6)    05162 Measles     109693564 (Traf6)    05168 Herpes simplex virus 1 infection     109693564 (Traf6)    05169 Epstein-Barr virus infection     109693564 (Traf6)   09171 Infectious disease: bacterial    05132 Salmonella infection     109693564 (Traf6)    05135 Yersinia infection     109693564 (Traf6)    05133 Pertussis     109693564 (Traf6)    05152 Tuberculosis     109693564 (Traf6)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     109693564 (Traf6)    05140 Leishmaniasis     109693564 (Traf6)    05142 Chagas disease     109693564 (Traf6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     109693564 (Traf6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     109693564 (Traf6)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ccan04131]     109693564 (Traf6)    04121 Ubiquitin system [BR:ccan04121]     109693564 (Traf6) Enzymes [BR:ccan01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      109693564 (Traf6) Membrane trafficking [BR:ccan04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     109693564 (Traf6) Ubiquitin system [BR:ccan04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    TRAF proteins     109693564 (Traf6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TRAF-mep_MATH MATH_2 zf-TRAF TRAF6_Z2 zf-C3HC4_2 zf-C3HC4 zf-RING_UBOX zf-RING_2 zf-C3HC4_3 zf-C3HC4_4 zf-TRAF_2 zf-RING_5 Spc29 TRAF3_RING zf-RING_11 RING_XB3-XBAT31 Med21 PUMA_CC SlyX DUF4455 U-box PspA_IM30 DUF7310 EzrA DUF6271 Myosin_tail_1 DUF16 Sina_ZnF DUF3450 DUF7607 TMF_DNA_bd CENP-F_leu_zip DM Motif Other DBs NCBI-GeneID:  109693564 NCBI-ProteinID:  XP_020030506 UniProt:  A0A250YJH2 LinkDB All DBs Position Unknown AA seq 537 aa AA seqDB search MSLLNCENSCGSSQAESDCCAAMASSCSATAKDDSVSGTSSTGNLSSSFMEEIQGYDVEF DPPLESKYECPICLMALREAVQTPCGHRFCKACIIKSIRDAGHKCPVDNEILLENQLFPD NFAKREILSLTVKCPNEGCFHKMELRHLEDHQAHCEFALMNCPQCQRPLQKCQLNVHILQ DCPRRQVSCRNCAVSMAFEDKEIHDQNCPLANVTCEYCNTMLIREQMPNHYDLDCPTAPI PCTFSTFGCHDKMQRNHLARHLQENTQSHMRMLAQAVHSLSLALPPIPPRDITPYEPRRS SGCNPEDENFRETIQQLERRLVRQDHQIRELTAKMETQSMYVSELKRTIRTLEDKVAEIE AQQCNGIYIWKIGNFGMHLKSQEEEKPVVIHSPGFYTGKPGYKLCMRLHLQLPTAQRCAN YISLFVHTMQGEYDSHLPWPFQGTIRLTILDQSEAPTRQNHEEVMDAKPELLAFQRPTIP RNPKGFGYITFMHLEALRQRTFIKDDTLLVRCEVSTRFDMGGLRKEGFQPRSTDAGV NT seq 1614 nt NT seq  +upstreamnt  +downstreamnt atgagtctgttaaactgtgaaaacagctgtgggtccagccaggctgaaagtgactgctgt gctgccatggccagctcttgcagtgcaacagcaaaagatgacagtgtgagtggaaccagc agcacagggaacctgtccagttcctttatggaagaaatccagggatatgatgtagaattt gacccacccttggaaagcaagtatgaatgccccatctgcttgatggcattacgggaagcg gtgcaaacaccatgtggccataggttctgcaaagcctgcatcatcaaatcgataagagat gcaggtcacaagtgtccagttgacaatgaaatactactggaaaatcaactatttcctgac aattttgcaaaacgagagattctttctctgacggtaaagtgtccaaatgaaggttgtttt cacaagatggaactgagacatcttgaggatcatcaagcacattgtgagtttgctcttatg aattgtccccaatgccaacgtcccttgcaaaaatgtcagcttaatgttcacattctgcag gattgtccaaggagacaagtttcttgtagaaattgtgctgtatccatggcatttgaagat aaagagatccatgaccagaactgtccattggcaaatgtcacctgcgaatactgcaatacc atgctcatcagagaacagatgccgaatcattatgatctagactgcccaacagccccaatc ccatgcacattcagtacttttgggtgccatgataagatgcagaggaatcacctggcacgc cacctacaagaaaatacgcagtctcacatgagaatgttggcccaggctgttcatagctta agccttgctttaccacccattcctccacgtgatataacgccatatgaaccccggcgttcc tctggctgtaacccagaggatgagaatttccgagaaaccattcaacagttagagcgtcgc cttgtaagacaggaccatcaaatccgagagctgactgctaaaatggaaactcagagtatg tatgtaagtgagctcaaacgaactattcgaacccttgaggacaaagttgctgaaatcgaa gcacaacagtgcaatgggatttacatttggaagattggcaactttgggatgcacttgaaa tctcaagaagaggaaaaacctgttgtcattcatagccctggattctacacaggcaaacct gggtacaaactatgcatgcgcttgcaccttcagttaccaactgctcagcgctgtgcaaac tatatatccctctttgtccacacaatgcaaggagaatatgacagccatctcccttggccc ttccagggtacaatacgccttacaattcttgatcagtctgaagcaccaacaaggcaaaac catgaagaggtaatggatgccaaaccagagctgcttgccttccaacggcccacaatccca cggaaccccaaaggttttggttatataacatttatgcacctggaagccttaagacaaaga accttcattaaggatgatacgttattagtgcgttgtgaagtctccacccgctttgacatg ggtggccttcggaaagagggcttccagccacgaagtactgatgcaggggtatag

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