Castor canadensis (American beaver): 109695320 Help Entry 109695320         CDS       T04791                                  Name (RefSeq) tyrosine-protein kinase ZAP-70   KO K07360   tyrosine-protein kinase ZAP-70 [EC:2.7.10.2] Organism ccan  Castor canadensis (American beaver) Pathway ccan04014   Ras signaling pathway ccan04064   NF-kappa B signaling pathway ccan04650   Natural killer cell mediated cytotoxicity ccan04658   Th1 and Th2 cell differentiation ccan04659   Th17 cell differentiation ccan04660   T cell receptor signaling pathway ccan05135   Yersinia infection ccan05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ccan05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     109695320    04064 NF-kappa B signaling pathway     109695320  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     109695320    04660 T cell receptor signaling pathway     109695320    04658 Th1 and Th2 cell differentiation     109695320    04659 Th17 cell differentiation     109695320  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     109695320   09171 Infectious disease: bacterial    05135 Yersinia infection     109695320   09163 Immune disease    05340 Primary immunodeficiency     109695320  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:ccan01001]     109695320 Enzymes [BR:ccan01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      109695320 Protein kinases [BR:ccan01001]  Non-receptor tyrosine kinases   SYK family    109695320 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 DUF7145 DUF7063 ABC1 Haspin_kinase SH2_1 RIO1 Kdo Motif Other DBs NCBI-GeneID:  109695320 NCBI-ProteinID:  XP_020033353 UniProt:  A0A250YK54 LinkDB All DBs Position Unknown AA seq 617 aa AA seqDB search MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVYNVRFHHFS IERQLNGTYAIAGGKAHCGPAELCEFYSLDPDGLPCNLRKPCNRPSGLEPQPGVFDNLRD AMVRDYVRQTWKLEGDALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSG AQTDGKFLLRPRKEQGTYALSMIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK LKADGLIYCLKEVCPNSASTAGAAAPTLPAHPSTFTQPQRRVDTLNSDGYTPEPARLASP DKPRPMPMDTSVYESPYSDPEELKDKKLFLKRENLLVADIELGCGNFGSVRQGVYRMRKK QIDVAIKVLKHSTEKADKDEMMREAQIMHQLDNPYIVRLIGVCKAEALMLVMEMAGGGPL HKFLLGKKEEVPVSNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGL SKALGADDSYYTARSAGKWPLKWYAPECINFRKFSSRSDVWSYGVTMWEAFSYGQKPYKK MKGPEVLDFIKQGKRMECPPECPPEMYALMSDCWIYKWEDRPDFLTVEQRMRSYYYSLAS KAEGPSQCGQGVEAASV NT seq 1854 nt NT seq  +upstreamnt  +downstreamnt atgccggaccccgcggcgcacctgcccttcttctatggcagcatctcgcgagctgaggcc gaggagcacctgaagctggcgggcatggccgacgggctgttcctgctgcgccagtgcctg cgctcgctgggcggctacgtgctgtcgctggtgtacaacgtgcgcttccaccacttctcc atcgagcgccagctcaatggcacctacgccatcgcaggcgggaaggcgcactgtggtccg gccgagctctgcgagttctactcgctggaccctgacggactgccctgcaacctgcgcaag ccttgcaaccggccatcgggcctcgagccacagcccggagtcttcgacaacctgcgcgac gcaatggtgcgtgactacgtgcgccagacgtggaagctggagggcgacgccctggagcag gcaatcatcagccaggccccgcaggtggagaaactcatagctaccacagcccatgagagg atgccctggtaccacagcagcctgacacgcgaggaggcggagcgcaaactctactctgga gcacagactgacggcaagttcctgctgaggccccgtaaggaacagggcacatacgcactg tccatgatctatgggaaaaccgtgtaccactacctcatcagccaggacaaggccggcaag tactgcattcccgaggggaccaagtttgacacactctggcagctggtggagtacctgaag ctgaaggccgatgggctcatctattgcctgaaagaggtctgccccaatagtgcgagcact gcaggggctgctgctcccacactcccagctcacccatccaccttcacccagcctcagaga cgggtggacaccctcaactcagatggatatacccccgagccagcacgtctagcatctcca gacaagccacggccaatgcccatggatacaagtgtgtatgagagtccctacagtgaccct gaggagctcaaggacaagaagctcttcctgaagcgtgagaacctccttgtggctgatatt gaactcggctgtggcaactttggctcagtgcgccagggtgtctaccgcatgcgcaagaag cagattgacgtggccatcaaagtcctgaagcacagcacagagaaggcagacaaggatgag atgatgcgtgaggcacagatcatgcaccagctggacaacccctacatcgtacggctcatc ggggtgtgcaaggccgaggcgctcatgctcgtcatggagatggcaggtggtgggcccctg cacaaattcctgcttggaaagaaggaggaggtccccgtgagcaatgtggcagagctgctg caccaagtgtccatggggatgaagtacctcgaggagaagaactttgtgcaccgcgacctg gcggcccgcaatgtcctgctggtcaacaggcactacgccaagatcagtgactttggtctt tccaaggcgctaggtgctgatgacagctactacacggcccgctcagcagggaagtggcct ctaaagtggtatgcgcctgagtgcatcaacttccgcaagttctccagtcgcagtgatgtc tggagctatggggtgaccatgtgggaggctttctcctatggtcagaagccctacaagaag atgaaaggccccgaggtcttggacttcatcaagcagggcaagcggatggagtgcccacca gagtgtccacctgaaatgtacgcactcatgagcgactgctggatctacaagtgggaggac cgtccggacttcctgacagtggaacagcgcatgcggtcctattactacagcctggcgagc aaggcagagggcccctcacaatgtggacagggagtggaggctgcgagtgtctga

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