Castor canadensis (American beaver): 109695579
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Entry
109695579 CDS
T04791
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan04120
Ubiquitin mediated proteolysis
ccan04144
Endocytosis
ccan04330
Notch signaling pathway
ccan04668
TNF signaling pathway
ccan04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
109695579
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
109695579
04668 TNF signaling pathway
109695579
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
109695579
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
109695579
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ccan04131
]
109695579
04121 Ubiquitin system [BR:
ccan04121
]
109695579
Enzymes [BR:
ccan01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
109695579
Membrane trafficking [BR:
ccan04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
109695579
Ubiquitin system [BR:
ccan04121
]
Ubiquitin ligases (E3)
HECT type E3
109695579
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
PQQ_2
Motif
Other DBs
NCBI-GeneID:
109695579
NCBI-ProteinID:
XP_020033780
UniProt:
A0A8B7VTW1
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGSQLVSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVTVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSICLDGLQLDAEIVTNGETTCSESTSQNDDGSRPKDEARVSTNGS
DDPEDTGSGENRKVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTSTTTNISEGATSGLIIPLTISGGSGPRPLNPVTQAPLPPGWEQRVDQHGR
VYYVDHVEKETTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQSKEFDPLGPLPPGWEKRTDNNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGVPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKVQYFRFWCQQLTMPQHIKITVTRKTLFEDSFQQIMSFNPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFHFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggatcacaacttgtttcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtaatctcagcaaaacttaaagaaaataaaaagaattggtttggaccaagc
ccttatgtagaagtcacagtagatggacagtcaaagaagacagaaaaatgcaacaataca
aacagtcccaaatggaagcaacctcttacagttatcgttaccccagtgagtaaattacat
ttccgcgtgtggagtcaccagacgctgaaatctgatgttttattgggaactgctgcatta
gatatttatgaaacattaaagtcaaacaatatgaaacttgaagaagtggttgtgactttg
cagcttgtaggtgacaaagagccaacagaaacaataggagacttatcaatttgtctcgat
ggtctgcaactagatgctgaaattgttactaatggtgaaactacatgctcagaaagtact
tcacagaatgatgatggctctagacccaaggatgaagcaagagtgagcacaaatggatca
gatgatcctgaggatacaggatctggtgaaaataggaaggtcaatgggaacaattctcca
tcgctctcaaatggtggttttaagccctctagacctccaagaccttcacggccacctcca
cccaccccacgtagaccagcatcggtcaatggttcaccatctgccacttccgaaagtgat
ggatctagtacaggctctctaccaccaacaagtacaactacaaatatatctgaaggagca
acatctggattaataattcctcttactatatctggaggctcagggcctaggccattaaat
cctgtaactcaagctcccctaccacctggttgggagcagagagtggaccagcatggacga
gtttattatgtagatcatgttgaaaaagaaacaacatgggacagacctgaacctctgcct
cctggctgggaacggcgggttgacaatatgggacgtatttattatgttgaccatttcaca
agaacaacaacatggcagaggccaacattggaatccgtccgaaactatgaacagtggcag
ctacaacgtagtcaacttcaaggagcaatgcagcagtttaaccagagattcatttatggg
aatcaagatttgtttgctacatcacaaagtaaagaatttgatccccttggtcctctgcca
cctggatgggagaagagaactgataacaatggcagagtatattttgtcaaccacaacact
cgaattacacaatgggaagaccccagaagtcaaggtcaattaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtagatggagttccgtattttgttgaccacaacaga
agaacaaccacctatatagatccccgcacaggaaaatctgccttagacaatggaccacag
atagcatatgttcgagacttcaaggcaaaagttcagtatttccggttttggtgtcagcaa
ctgaccatgccacagcacataaagatcacagtgacaagaaaaacattgtttgaggattcc
tttcaacagataatgagcttcaatccccaagacctgcgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaagtgttgaaccccatgtattgcctgtttgaatatgcagggaaggacaactactgc
ttgcagataaaccctgcttcttacatcaatccagatcacttgaaatactttcattttatt
ggcaggtttattgccatggctctgttccatgggaaatttatagacaccggtttttcttta
ccattctataaacgtatcttgaacaaaccagttggacttaaggatttagaatctattgat
ccagaattttacaattctctaatctgggttaaagaaaacaatattgaggaatgtggtttg
gaaatgtacttctccgttgataaagaaattttaggtgaaattaagagtcatgatttgaaa
cccaatggtggcaatattcttgtgacagaagaaaataaagaagaatacattagaatggta
gctgagtggaggttatctagaggtgttgaagaacagacacaagctttctttgaaggcttt
aatgaaattcttccccagcagtatttgcagtacttcgatgcaaaggaattagaggtactt
ttatgtggaatgcaagagattgatttgaatgactggcaaagacatgccatctaccgtcat
tatactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctacagtttgttactggaacctgccgattgccagtaggagga
tttgctgacctcatggggagcaatggaccacagaaattctgcattgaaaaagttgggaaa
gaaaattggttacccaggagtcatacctgttttaaccgcctagaccttccaccttacaag
agctatgagcaactgaaggaaaaactgttgtttgccattgaagaaacagaaggatttgga
caagagtaa
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