Castor canadensis (American beaver): 109697041
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Entry
109697041 CDS
T04791
Symbol
Map3k5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan01524
Platinum drug resistance
ccan04010
MAPK signaling pathway
ccan04071
Sphingolipid signaling pathway
ccan04141
Protein processing in endoplasmic reticulum
ccan04210
Apoptosis
ccan04530
Tight junction
ccan04668
TNF signaling pathway
ccan04714
Thermogenesis
ccan04722
Neurotrophin signaling pathway
ccan04932
Non-alcoholic fatty liver disease
ccan04936
Alcoholic liver disease
ccan05010
Alzheimer disease
ccan05012
Parkinson disease
ccan05014
Amyotrophic lateral sclerosis
ccan05016
Huntington disease
ccan05017
Spinocerebellar ataxia
ccan05022
Pathways of neurodegeneration - multiple diseases
ccan05208
Chemical carcinogenesis - reactive oxygen species
ccan05417
Lipid and atherosclerosis
ccan05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
109697041 (Map3k5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
109697041 (Map3k5)
04668 TNF signaling pathway
109697041 (Map3k5)
04071 Sphingolipid signaling pathway
109697041 (Map3k5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
109697041 (Map3k5)
09144 Cellular community - eukaryotes
04530 Tight junction
109697041 (Map3k5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
109697041 (Map3k5)
09159 Environmental adaptation
04714 Thermogenesis
109697041 (Map3k5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
109697041 (Map3k5)
09164 Neurodegenerative disease
05010 Alzheimer disease
109697041 (Map3k5)
05012 Parkinson disease
109697041 (Map3k5)
05014 Amyotrophic lateral sclerosis
109697041 (Map3k5)
05016 Huntington disease
109697041 (Map3k5)
05017 Spinocerebellar ataxia
109697041 (Map3k5)
05022 Pathways of neurodegeneration - multiple diseases
109697041 (Map3k5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
109697041 (Map3k5)
05418 Fluid shear stress and atherosclerosis
109697041 (Map3k5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
109697041 (Map3k5)
04932 Non-alcoholic fatty liver disease
109697041 (Map3k5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
109697041 (Map3k5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccan01001
]
109697041 (Map3k5)
Enzymes [BR:
ccan01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
109697041 (Map3k5)
Protein kinases [BR:
ccan01001
]
Serine/threonine kinases: STE group
STE11 family
109697041 (Map3k5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
FPP
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
109697041
NCBI-ProteinID:
XP_020035993
UniProt:
A0A8C0WG25
LinkDB
All DBs
Position
Unknown
AA seq
1375 aa
AA seq
DB search
MGTEAGEGITFSVPPFASSAFSTFHEGSSCRRGGAATVAVGEPSQLPPPPPGSFWNVESA
AAPGTSGCPAATSGSNATRGRGNSGSGGGRRTTVAYVINEASQGQLVVAESEALQSLREA
CEAVGATLETLHFGKLDFGETTVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMAN
NIILYCDTNSDSLQSLKEVICQKNTMCTGNYTFVPYMVTPHNKVYCCDSSFMKGLTELMQ
PNFELLLGPICLPLVDRFVQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARI
RQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHLHVKFHYAFAL
NRRNRPGDRAKALDIMIPMVQCEGQVASDMYCLVGRIYKDMFLDSNFMDTESRDHGASWF
KKAFESEPTLQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLENLQSYWEVG
FFLGASVLANDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTPEQPVAKEELV
DFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEFEEKTISIWHVLPDDKKGI
HEWNFSASSVRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGR
STEEGDCEGDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYS
QPLHEEIALHKHLKHKNIVQYLGSLSDNGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQT
IGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETF
TGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKV
HPEIPESMSAEAKAFILKCFEPDPDKRACANDLLIDEFLKVSSKKKKTQPKLSALSTGSN
EYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDVKGIRTLFLG
IPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEE
PKLKWEHITTLVTSLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVN
KVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADPEDLDVEDDHE
EAPSNQTVRRPQAIIDDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLLEEL
VRKEKELQALLHQAIEEKDQEIRHLKLKSEPIDIPGLPVCHPNSPGTATEDSELTSWLRE
NGADEDTISRFLAEDYTLVDVLYYVTRDDLKCLRIRGGMLCTLWKAIIDFRDKHT
NT seq
4128 nt
NT seq
+upstream
nt +downstream
nt
atgggcaccgaggctggcgagggcatcacgttctccgtgccgcccttcgcctcctcggcc
ttctccaccttccacgagggcagcagctgccggaggggaggagcggcgactgtggccgtg
ggtgagccaagccagctaccgccgccgccaccgggcagcttctggaacgtggagagcgcc
gccgcccctggcacctctgggtgtcctgctgccacctccgggagcaacgccacccggggc
cggggcaactctggcagtgggggcggccgacggaccaccgtggcgtatgtgatcaacgaa
gcgagccaggggcagctggtggtggccgagagcgaggccctgcagagcctgcgggaggcg
tgcgaggcggtgggcgccaccctggagaccctgcactttgggaaactggacttcggggaa
accacggtgctggaccggttttacaacgcagatattgctgtggtagagatgagtgatgcc
ttccggcagccgtccttgttttaccatcttggggtgagagaaagcttcagcatggccaac
aatatcattctctactgtgacaccaactcagactctctgcagtccctcaaggaagtcatt
tgccagaagaatactatgtgcacagggaactacacatttgtcccctacatggtaacacca
cacaacaaggtctactgctgtgatagcagcttcatgaagggcttgacagagctcatgcag
cccaacttcgagctcctgcttgggcccatctgcttacctctcgtggaccgattcgtccag
cttctgaaggtggcacaagcgagttccagccagtacttccgggaatctatacttaatgac
atcaggaaggctcggaacttatacactgggaaagaattggcagctgaattggcgagaatt
cggcagcgagttgataatattgaagtcttaactgcagacattgtcatcaatctgttactt
tcctacagagatatccaggactatgattccattgtgaagctggtagaaactttagaaaaa
ctgcccaccttcgatttggcctcccatctccatgtgaagtttcattatgcgtttgcactg
aataggagaaatcgccctggagatagagcaaaagctcttgatattatgattcccatggtg
caatgtgaagggcaagttgcttcagatatgtattgcctagttggtcgaatctacaaagat
atgtttttggactctaatttcatggatactgaaagtagagaccatggagcttcttggttc
aaaaaggcatttgaatctgagccaactctacagtcaggaattaattatgcagtcctcctc
ctggcagcaggacaccagtttgaatcttcctttgagcttcggaaagttggagtgaagcta
agtagccttcttggtaagaagggaaacttggaaaacctccagagctactgggaagttgga
ttttttctgggagctagtgtcctggccaatgaccacctgagagtcattcaagcatctgaa
aagcttttcaaactgaagacgccagcatggtacctcaagtcaattgtggagacaattttg
atatataagcattttgtgaaactgacaccagaacagcctgtggccaaggaagaactggtg
gacttttggatggatttcctggttgaggccacaaagacagatgttactgtagttagattt
ccagtcttaatattagaaccaaccaaaatctatcagccttcttacttgtctatcaacaat
gaattcgaagaaaagacaatatctatctggcatgtgcttcctgatgacaagaaaggcata
catgagtggaattttagtgcttcctctgtcaggggcgtgagtatttctaaatttgaagaa
cgatgctgttttctttatgtactgcacaattctgatgatttccaaatctatttctgtaca
gaacttcactgtaagaagttttttgaaatggtgaacaccattaccgaagagaaggggaga
agcacggaagaaggggactgtgaaggtgactccctggagtatgactacgaatatgatgaa
aatggtgaccgagttgtgttgggaaaaggcacttacgggatagtctatgcaggtcgagac
ttgagcaaccaggtccgaattgctattaaagaaatcccagagagagacagcagatactcc
cagcccctgcatgaagagatagccttgcataagcatctcaagcacaaaaacattgtccaa
tatctgggctctctaagtgacaatggcttcattaaaatcttcatggagcaggtcccagga
ggaagtctttctgctctccttcggtccaaatggggcccattaaaagacaatgagcaaaca
attggcttttatacaaagcaaatactggaaggattaaaatacctccatgacaatcaaata
gttcaccgggatataaagggtgacaatgtactgattaatacatacagtggcgttctcaag
atctctgactttgggacatcaaagagacttgctggcataaatccatgtactgaaactttt
actggtacgctccagtatatggcaccagaaataattgataaaggaccacgaggttatggg
aaggcagctgacatttggtctttggggtgcacgatcatcgaaatggccacaggaaaacca
ccgttttatgaactcggagagccgcaagcagccatgttcaaggttgggatgtttaaagtc
caccctgagatcccagagtccatgtctgcagaggccaaggcattcatattgaaatgtttt
gaacctgaccctgacaagagagcatgtgctaatgacttgcttattgacgagttcttaaaa
gtttccagcaaaaagaaaaagacacaacccaagctttcagctctttcgactggatcaaat
gagtacctcaggagcatctccctgccagtccctgtcctggtggaagacaccagcagcagt
agtgagtatggctccgtgtcccccgacactgagttgaaggtggaccccttctctttcaaa
accagagccaagtcctgtggagaaaaagatgtgaagggaatacggacgctgtttttgggc
attccagatgaaaattttgaagatcatagtgcgccaccttcccctgaagaaaaagattct
ggattctttatgctgaggaaggacagtgaaaggcgagccacccttcataggatcctgacc
gaggaccaggataaggttgtgaggaacttaatggagtccttagctcagggtgctgaggaa
cccaagctgaaatgggaacacatcaccaccctcgtcacgagcctcagggagtttgtgagg
tccactgaccgaaaaatcatagctaccaccctgtcaaagctgaaactagagctggacttc
gacagccatgggatcagtcaagtgcaggtggtcctctttggtttccaggatgcggtaaat
aaagttcttcggaaccataacatcaagccacattggatgtttgccctggacagcatcatc
cgaaaggctgtgcagacggctattaccatcctggtgccagaactgaggccacattttagc
cttgcctcagagagtgacacggctgatccggaagacttggatgtagaagatgaccatgaa
gaagcaccttcaaatcagactgtccgaagacctcaggccatcatcgacgatgctgtggct
acctctggggtgagcacactcagctccactgtatcccacgattcccaaagtgctcatcgg
tcactcaatgtgcagcttggcaggatgaaaatagaaacaaacagattactggaagaattg
gttcggaaagagaaggaattacaagcactccttcatcaagctattgaagaaaaagaccaa
gaaattagacacctgaagcttaagtccgaaccaatagatattcccgggttgcctgtgtgc
cacccgaattctcctggcacagccactgaggattctgaactcaccagctggctgagagaa
aatggagctgatgaagacactataagtcggtttttggctgaggattacacactggtggat
gttctctactacgttacacgtgatgatttaaaatgtctgagaataaggggaggaatgctg
tgtacactgtggaaagccatcattgactttcgagacaaacacacttga
DBGET
integrated database retrieval system
