Castor canadensis (American beaver): 109697922 Help Entry 109697922         CDS       T04791                                  Symbol Hk2 Name (RefSeq) hexokinase-2 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism ccan  Castor canadensis (American beaver) Pathway ccan00010   Glycolysis / Gluconeogenesis ccan00051   Fructose and mannose metabolism ccan00052   Galactose metabolism ccan00500   Starch and sucrose metabolism ccan00520   Amino sugar and nucleotide sugar metabolism ccan00524   Neomycin, kanamycin and gentamicin biosynthesis ccan01100   Metabolic pathways ccan01200   Carbon metabolism ccan01250   Biosynthesis of nucleotide sugars ccan04066   HIF-1 signaling pathway ccan04910   Insulin signaling pathway ccan04930   Type II diabetes mellitus ccan04973   Carbohydrate digestion and absorption ccan05230   Central carbon metabolism in cancer Module ccan_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ccan_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc Brite KEGG Orthology (KO) [BR:ccan00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     109697922 (Hk2)    00051 Fructose and mannose metabolism     109697922 (Hk2)    00052 Galactose metabolism     109697922 (Hk2)    00500 Starch and sucrose metabolism     109697922 (Hk2)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     109697922 (Hk2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     109697922 (Hk2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     109697922 (Hk2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     109697922 (Hk2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     109697922 (Hk2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     109697922 (Hk2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     109697922 (Hk2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ccan04131]     109697922 (Hk2) Enzymes [BR:ccan01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      109697922 (Hk2) Membrane trafficking [BR:ccan04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     109697922 (Hk2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 FGGY_N Motif Other DBs NCBI-GeneID:  109697922 NCBI-ProteinID:  XP_020037415 UniProt:  A0A8C0WEJ4 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MIASHMIACLFTELNRNQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDIMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV EGRDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGTLNDIRTEFDREIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFQGKVSSELLTTGSFETKDVSDIEADKDGIQKAYEVLVRLG LNPLQEDCVATHRICQIVSTRSASLCAATLAAVLWRIKENKGEERMRSTIGVDGSVYKKH PHFAKRLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEPLKLS HEQLLEVKRRMKIEMERGLSKETHAIAPVKMLPTYVCATPDGSEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGEELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPDCEVGLIVGTGSNACYMEEMCNVELVDGEEGRMCVNMEWGAFGDNGCLDD FRTEFDVAVDALSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgattgcctcgcatatgatcgcctgcctcttcactgagctcaaccgtaaccaagtgcag aaggtcgaccagtatctctaccacatgcgtctttctgatgagacccttctggagatttct aagcggttccgtaaggagatggagaaaggacttggagccaccacccaccccactgcttct gtgaaaatgctacccacctttgtgaggtccaccccagatgggacagaacatggagagttc ctggctctggaccttggagggactaacttccgtgtgctccgggtgagagtaacagacaat gggctccagaaggtggagatggagaaccagatctatgccatccctgaggacattatgcga ggcagtggcacccagctgtttgaccatattgctgaatgcctggccaacttcatggataag ctacaaatcaaagacaagaagctccccttgggttttaccttctcattcccctgccaccaa actaaactagatgagagtttccttgtctcatggaccaaagggtttaagtccagtggagtg gaaggcagagatgtggtgactctgatccggaaggccatccagcggagaggggactttgat attgacattgtggccgtggtgaatgacacagttggaaccatgatgacctgtggttatgat gatcagaactgtgagattggtctcattgtgggcactggcagcaatgcctgctacatggag gagatgcgtcacatcgacatggtagaaggcgatgaggggcggatgtgcatcaacatggag tggggggcctttggggatgatggcaccctcaatgatatccgcactgagtttgaccgagag atcgacatgggctcgctgaaccctgggaagcaactatttgagaagatgatcagtgggatg tacatgggggagctggtgaggctcatcctggtgaagatggccaaggaggagctgctcttc caggggaaggtcagctcagagctcctcaccactggctccttcgagaccaaagatgtttca gatattgaggcggataaggatggtatccagaaagcctatgaggttctggtgcggctgggc ctgaatccactacaggaggactgtgtggccactcaccggatctgccagatcgtgtccaca cgctcagccagcctgtgtgcagccaccctggctgccgtgctgtggcgcatcaaggagaac aagggcgaggagcgaatgcgctccaccattggggttgatggctctgtctacaagaaacac ccccattttgccaagcgtcttcacaagaccgtgaggaggctggtgcctgactgcgatgtt cgcttccttcgctccgaggatggcagtggaaaaggggcagccatggtgacggcagtagct tatcggctcgctgaccaacaccgagcccgccaaaagaccttagagcctctgaagctgagc catgagcaactgctggaggtaaagagaaggatgaagattgaaatggagcgaggtctgagc aaggagacacatgccattgcccctgtgaagatgctgcccacctatgtgtgtgccacccct gatggctcagaaaaaggagacttcctggccttggaccttggcggaacaaatttccgggtc ctgctggtgcgtgtgcggaacgggaagcgtcgaggagtggagatgcacaacaagatctac tccattcctcaggaggtcatgcatggcacaggagaggagctctttgatcacatcgtccag tgcatcgctgacttcctggagtatatgggcatgaagggtgtgtccttgcctctgggtttc accttctcctttccctgccagcagaacagcctggatgagagcatcctcctcaaatggaca aaaggcttcaaggcgtcaggctgtgagggtgaggacgtggtcaccctgctgaaggaagcg attcaccggagagaggagtttgacctggatgtggttgctgtggtgaatgacacagtagga actatgatgacctgtggctatgaagaccctgactgtgaagttggcctcatcgttggcaca ggcagcaacgcctgctacatggaggagatgtgcaacgtggagctggtggatggagaggag gggagaatgtgtgtcaacatggagtggggggcctttggggacaacggatgcctggacgac ttccgcacggagtttgatgtggctgtagatgcactctctctcaacccgggcaaacagaga tttgagaaaatgatcagtggcatgtacttgggtgagattgttcggaacatcctcatcgat ttcaccaagcgtgggctgctcttccgtggccgcatctcagagcggctgaagacacgggga atctttgaaaccaagttcttgtcccagattgagagtgactgcctggccctgctgcaagtc cgcgccatcttgcaccacttggggcttgagagcacctgcgacgacagcatcatcgtcaaa gaggtgtgcactgtggtggcacggcgggcagctcagctttgtggtgcgggcatggctgcc gtggtggacaagatacgagaaaatcgtgggctggacactctcaaagtgacagttggtgtg gacgggaccctctacaagcttcatcctcactttgccaaagtcatgcatgagacggtaaag gacttggctcctaaatgcgatgtgtccttcctggagtctgaggatggcagcgggaagggg gcggctctcatcactgctgtggcatgccgcatccgtgaggctggacagcgatag

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