Castor canadensis (American beaver): 109700113 Help Entry 109700113         CDS       T04791                                  Symbol Thbs1 Name (RefSeq) thrombospondin-1   KO K16857   thrombospondin 1 Organism ccan  Castor canadensis (American beaver) Pathway ccan04015   Rap1 signaling pathway ccan04115   p53 signaling pathway ccan04145   Phagosome ccan04148   Efferocytosis ccan04151   PI3K-Akt signaling pathway ccan04350   TGF-beta signaling pathway ccan04510   Focal adhesion ccan04512   ECM-receptor interaction ccan04820   Cytoskeleton in muscle cells ccan05144   Malaria ccan05165   Human papillomavirus infection ccan05205   Proteoglycans in cancer ccan05206   MicroRNAs in cancer ccan05219   Bladder cancer Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     109700113 (Thbs1)    04350 TGF-beta signaling pathway     109700113 (Thbs1)    04151 PI3K-Akt signaling pathway     109700113 (Thbs1)   09133 Signaling molecules and interaction    04512 ECM-receptor interaction     109700113 (Thbs1)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     109700113 (Thbs1)    04148 Efferocytosis     109700113 (Thbs1)   09143 Cell growth and death    04115 p53 signaling pathway     109700113 (Thbs1)   09144 Cellular community - eukaryotes    04510 Focal adhesion     109700113 (Thbs1)   09142 Cell motility    04820 Cytoskeleton in muscle cells     109700113 (Thbs1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     109700113 (Thbs1)    05205 Proteoglycans in cancer     109700113 (Thbs1)   09162 Cancer: specific types    05219 Bladder cancer     109700113 (Thbs1)   09172 Infectious disease: viral    05165 Human papillomavirus infection     109700113 (Thbs1)   09174 Infectious disease: parasitic    05144 Malaria     109700113 (Thbs1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ccan04131]     109700113 (Thbs1)   09183 Protein families: signaling and cellular processes    00536 Glycosaminoglycan binding proteins [BR:ccan00536]     109700113 (Thbs1) Membrane trafficking [BR:ccan04131]  Endocytosis   Phagocytosis    Opsonins     109700113 (Thbs1) Glycosaminoglycan binding proteins [BR:ccan00536]  Heparan sulfate / Heparin   Extracellular matrix molecules    109700113 (Thbs1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  TSP_C TSP_3 TSP_1 TSP1_spondin VWC TSP1_CFP_C EGF_3 cEGF Laminin_G_3 TSP1_ADAMTS Laminin_G_2 TSP1_CCN EGF Laminin_G_1 Motif Other DBs NCBI-GeneID:  109700113 NCBI-ProteinID:  XP_020040747 UniProt:  A0A250YM75 LinkDB All DBs Position Unknown AA seq 1171 aa AA seqDB search MGLAWGLGVLFLLHVCGTNHIPESGGDNSVFDIFELTGATRKGSGRRLVKGPDPSSPAFR IENANLIPPVPDDKFQDLVDAVRAEKGFLLLASLRQMKKTRGTLLAIERKDHSGQIFSVV SNGKAGTLDLSLSIPGKHQVVSVEEALLATGQWKTITLFVQEDRAQLYIDCEKMESAELD VPIQTIFTRDLANIARLRVAKGDVNDNFQGVLQNVRFVFGTTPEDILRNKGCSSSTTNVL LTLDNNVVNGSSPAIRTNYIGHKTKDLQAICGISCDELSSMVLEVRGLRTIVTTLQDSIR KVTEENKELAKEWRKPPLCYHNGVQYKNNDEWTVDSCTECHCQNSVTICKKVSCPIMPCS NATVPDGECCPRCWPSDSADDGWSPWSEWTSCSATCGNGIQQRGRSCDSLNNRCEGSSVQ TRTCHIQECDKRFKQDGGWSHWSPWSSCSVTCGDGVITRIRLCNSPSPQMNGKPCEGEAR ETKACKKDACPINGGWSPWSPWDICSVTCGGGVQKRSRLCNSPTPQFGGKDCIGDVTENQ VCNKQDCPIDGCLSNPCFAGTKCTSYPDGSWKCGACPPGYSGNGIQCKDVDECKEVPDAC FNHNGEHRCKNTDPGYNCLPCPPRFTGSQPFGRGVEHAMANKQVCKPRNPCTDGTHDCNK NAKCNYLGHYSDPMYRCECKPGYAGNGIICGEDTDLDGWPNEDLVCVANATYHCKKDNCP NLPNSGQEDYDKDGIGDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPY NHNPDQADTDNNGEGDACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLE HNPDQLDSDSDRIGDTCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDD NDGIPDDRDNCRLVPNPDQKDSDGDGRGDACKDDFDHDNVPDIDDICPENVDISETDFRR FQMIPLDPKGTSQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERD DDYAGFVFGYQSSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNA LWHTGNTPGQVRTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIY DKTYAGGRLGLFVFSQEMVFFSDMKYECRDS NT seq 3516 nt NT seq  +upstreamnt  +downstreamnt atggggctggcctggggactcggtgtcctgttcctgctgcatgtgtgtggcaccaaccac attccagagtctgggggagacaacagcgtgtttgacatctttgaactcactggggccacc cgcaagggctctggtcgccgactggtgaagggccctgacccgtccagcccagctttccgg attgagaatgccaacctgattcctcccgtgcctgatgacaagttccaagacctggtggat gctgtgcgggcagagaaagggttcctcctcctggcctccctgaggcagatgaagaagacc cggggcacgctgctggccatagagcggaaagaccactctggccagatcttcagcgtggtc tccaatggcaaggcgggcaccctggacctgagcctgagcattccggggaagcaccaagtg gtgtccgtggaagaagctctcctggccacgggccagtggaagaccatcaccctgtttgtg caggaagacagggctcagctctacatcgactgtgagaagatggagagtgcagagctggat gtccccatccagaccatctttaccagggatctggctaacatcgccaggctccgcgttgca aagggagacgtcaatgacaatttccagggggtgctgcagaacgtgagatttgtctttgga actacaccagaagacatcctcaggaacaaaggctgctccagctcgactaccaatgtcctg ctcaccctcgacaacaatgtggtgaatggctccagccctgccatccgtactaactacatt ggccacaagacaaaggacctgcaagccatctgtggcatctcctgtgacgagctgtccagc atggtcctagaagtccggggcctgcgcaccatcgtgaccacgctgcaggacagcatccga aaagtgacggaagagaacaaagagttggccaaagaatggaggaagcctcccctctgctac cacaatggagttcagtacaagaataacgatgagtggactgtggacagctgcactgagtgt cactgtcagaactcagttaccatctgcaaaaaagtatcctgtcccattatgccctgctcc aatgccaccgtgcctgatggagagtgctgcccgcggtgttggcccagcgactctgcagac gatggctggtctccatggtctgagtggacctcgtgctctgccacatgtggcaatggaatt cagcagcgtgggcgctcctgtgacagcctcaacaatcgctgtgaaggctcctctgtccag acacggacctgccacatccaggagtgtgacaagagatttaaacaggatggtggctggagc cactggtccccgtggtcatcttgttctgtgacatgtggtgacggtgtgatcacgaggatc cggctctgcaactctcccagcccccagatgaatgggaagccatgtgaaggagaagctcgg gagaccaaagcatgcaagaaagacgcctgccccatcaatggaggctggagtccctggtca ccatgggacatctgttctgtcacctgtggaggaggggtgcaaaagcgaagccggctctgc aacagccccacaccccagttcggaggcaaagactgcattggtgatgtgacagaaaaccaa gtctgcaacaagcaggactgtccaattgatggatgcctatcaaacccctgctttgctggc accaagtgtactagctaccccgatggcagctggaaatgtggtgcttgcccccctggctac agtggaaatggcatccaatgcaaagatgtggatgagtgcaaagaagtgcctgatgcctgc ttcaaccacaacggagagcacagatgtaagaacacagaccctggctacaactgcctgccc tgcccaccgcgcttcactggctcgcagccctttggccggggcgttgaacacgccatggcc aacaaacaggtgtgcaaaccccgcaacccctgcacagatgggacacatgactgcaacaag aacgccaagtgtaactacctgggccactacagtgaccccatgtaccgctgtgagtgcaag cctggctatgctggcaacggcatcatctgtggggaggacacggaccttgacggctggcca aatgaggacctggtgtgtgtggccaatgcaacttaccactgcaaaaaggacaactgcccc aacctccccaactctggacaggaagactatgacaaggatgggattggtgatgcctgtgat gacgacgatgacaatgacaaaattccagatgatagggacaactgtccattccattacaac ccagcccagtatgactatgacagagatgacgtgggagaccgctgtgacaactgcccttac aaccacaacccagaccaggcagacacagacaacaatggggagggggacgcctgtgcggca gacattgatggagatggtatcctcaacgaacgagacaactgccagtacgtctacaatgtg gatcagagggacactgacatggatggagttggggatcagtgtgacaactgccccctggag cacaatccagatcagcttgactctgactcggaccgcattggagatacttgtgacaacaac caggacattgatgaagatggccaccagaacaatctggacaactgtccctatgtgcccaat gccaaccaggctgaccacgataaagatggcaagggagatgcctgtgaccacgatgatgac aatgatggcattcctgatgacagggacaactgcaggctggtacccaatcctgaccagaaa gactctgatggtgatggtcgaggtgatgcttgcaaagatgactttgaccacgacaatgtg ccagacattgatgacatctgtcctgagaatgttgatatcagtgagactgatttccgccga ttccagatgattcctctagatcccaaaggcacatctcaaaatgaccctaactgggttgtg cgccatcagggcaaagagttggtccagactgtcaactgtgaccctggactcgctgtaggt tacgatgagtttaatgctgtggacttcagtggcaccttcttcatcaacactgagagagat gatgattatgctggttttgtgtttggctaccagtccagcagccgcttctatgttgttatg tggaagcaagtaacccagtcctactgggacaccaaccccaccagagctcagggatactca ggcctgtctgtgaaagttgtgaactccaccacagggcctggcgagcacctgcggaatgcc ctctggcacacaggaaacacccctggtcaggtgcgcaccctgtggcatgaccctcgtcac ataggctggaaagatttcaccgcctacagatggcgtctcagccacaggccaaagacaggt ttcattagagtggtgatgtatgaagggaagaaaatcatggctgactccgggcccatctat gacaaaacctatgctggtggaagactgggactgtttgtcttctctcaagaaatggtgttc ttctctgacatgaaatacgaatgcagagattcctaa

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