Castor canadensis (American beaver): 109701180 Help Entry 109701180         CDS       T04791                                  Symbol Tlr2 Name (RefSeq) toll-like receptor 2   KO K10159   toll-like receptor 2 Organism ccan  Castor canadensis (American beaver) Pathway ccan04145   Phagosome ccan04151   PI3K-Akt signaling pathway ccan04613   Neutrophil extracellular trap formation ccan04620   Toll-like receptor signaling pathway ccan05132   Salmonella infection ccan05134   Legionellosis ccan05140   Leishmaniasis ccan05142   Chagas disease ccan05144   Malaria ccan05145   Toxoplasmosis ccan05146   Amoebiasis ccan05152   Tuberculosis ccan05161   Hepatitis B ccan05162   Measles ccan05168   Herpes simplex virus 1 infection ccan05169   Epstein-Barr virus infection ccan05170   Human immunodeficiency virus 1 infection ccan05171   Coronavirus disease - COVID-19 ccan05205   Proteoglycans in cancer ccan05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ccan05321   Inflammatory bowel disease ccan05323   Rheumatoid arthritis ccan05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ccan00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     109701180 (Tlr2)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     109701180 (Tlr2)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     109701180 (Tlr2)    04620 Toll-like receptor signaling pathway     109701180 (Tlr2)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     109701180 (Tlr2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     109701180 (Tlr2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     109701180 (Tlr2)    05161 Hepatitis B     109701180 (Tlr2)    05171 Coronavirus disease - COVID-19     109701180 (Tlr2)    05162 Measles     109701180 (Tlr2)    05168 Herpes simplex virus 1 infection     109701180 (Tlr2)    05169 Epstein-Barr virus infection     109701180 (Tlr2)   09171 Infectious disease: bacterial    05132 Salmonella infection     109701180 (Tlr2)    05134 Legionellosis     109701180 (Tlr2)    05152 Tuberculosis     109701180 (Tlr2)   09174 Infectious disease: parasitic    05146 Amoebiasis     109701180 (Tlr2)    05144 Malaria     109701180 (Tlr2)    05145 Toxoplasmosis     109701180 (Tlr2)    05140 Leishmaniasis     109701180 (Tlr2)    05142 Chagas disease     109701180 (Tlr2)   09163 Immune disease    05323 Rheumatoid arthritis     109701180 (Tlr2)    05321 Inflammatory bowel disease     109701180 (Tlr2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     109701180 (Tlr2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ccan04131]     109701180 (Tlr2)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ccan04147]     109701180 (Tlr2)    04054 Pattern recognition receptors [BR:ccan04054]     109701180 (Tlr2)    04090 CD molecules [BR:ccan04090]     109701180 (Tlr2)    00536 Glycosaminoglycan binding proteins [BR:ccan00536]     109701180 (Tlr2) Membrane trafficking [BR:ccan04131]  Endocytosis   Phagocytosis    Toll-like receptors     109701180 (Tlr2) Exosome [BR:ccan04147]  Exosomal proteins   Exosomal proteins of breast milk    109701180 (Tlr2) Pattern recognition receptors [BR:ccan04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    109701180 (Tlr2) CD molecules [BR:ccan04090]  Proteins   109701180 (Tlr2) Glycosaminoglycan binding proteins [BR:ccan00536]  Hyaluronan   Cell surface receptors    109701180 (Tlr2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  LRR_8 TIR LRR_4 TIR_2 LRR_9 LRR_1 LRR_5 LRR_LRWD1 LRRCT Motif Other DBs NCBI-GeneID:  109701180 NCBI-ProteinID:  XP_020042204 UniProt:  A0A250YL67 LinkDB All DBs Position Unknown AA seq 782 aa AA seqDB search MPHVLWTVWALGTMISLPKEGTPDQASLSCDPAGVCDGSSRSLTSIPLWLTAAMKSLDLS DNDIAYVGRGDLQSCVNLQALVLKSNRIHTIEENAFSSLHSLQHLDLSKNYLSNLSASWF RPLSSLKFLNLLENPYKTLGETSLFFHLSNLQTLRVGSAATFSEIQRVDFAGLTFLEELE ISASNLQRYESESLKSIQNISHLILHLKQPTLLLGIFVDLLNSVEYLELRDINVNRFYFS ELSVHETNSPIRKLTFTSVYFSDESFNEVLKLLSYTPGLLEVELDDCTLDGVGNFRASEK VKDLGNIETVTIRRLHIPKFFLFYDLSTVYSLAKTVKRVTVENSKVFLVPCSFSRHLKSL EYLDLSENLMVEEYLKNSACEDGWPSLQTLILRQNHLTFIEKTAEVLLTLKNLTDLDVSK NSFHFMPETCQWPKKMRYLNLSSTRIQSLTSCLPQTLEVLDVDNNNLNSFTLLLPQLKEL YISRNKLKTLPDASFLPVLLVMKVRKNTINTFSKEQLDSFHHLKSLEAGGNNFVCSCELL SFTQEQPALAKVLIDWPDNYLCDSPAHVRGQRVQDARLSASECYKAALVSGVCGILVLLI LLIVGLCHRFHGLWYVRMMWAWLQAKRKPRKAPGRDVCYDAFVSYSEHDSYWVENLLVQE LENLDPPFKLCLHKRDFVPGKWIIDNIIDCIEKSHKTVFVLSENFVRSEWCKYELDFSHF RLFDENNDAAILVLLEPIEKKAIPQRFCRLRKIMNTKTYLEWPRDEAQQEGFWVNLRTAI KS NT seq 2349 nt NT seq  +upstreamnt  +downstreamnt atgccacatgttttgtggacagtgtgggccttggggaccatgatcagcctccccaaggaa ggaaccccagatcaggcttctctgtcatgtgaccctgctggtgtctgtgacggcagctcc aggtctctcacttccatccccttatggctcactgcagccatgaaaagcctcgatctgtcc gacaatgacatcgcctacgtgggccgaggtgacctgcagagctgcgtgaacctccaggcg ctggtgctcaagtccaacagaatccacaccatagaggaaaatgccttttcttccctgcac agtctccagcatctggacttgtccaaaaactatttatctaatttgtcagcctcctggttc aggcccctttcctccctgaaattcttaaacttactggaaaatccttataaaacccttggg gaaacatcacttttttttcacctctcaaatttgcaaaccctgagggttggaagtgctgcc accttctctgagattcagagagtagattttgctggactcacctttctcgaggaactcgaa attagtgcgtcaaatctccagagatatgagtcagaaagtttgaagtccattcagaacatc agtcacctgattcttcacctgaagcagccaaccttactgctggggatttttgtggatctc ttaaattctgtggagtatttagaactgagagatatcaacgtgaacaggttctacttttca gagctatctgtccatgagacaaattcaccaatcagaaagttgacattcacaagtgtgtac ttctccgatgaaagctttaacgaagttctgaaactgttgagttacactcctggactgtta gaggtggaacttgatgactgtaccctggatggagttggcaattttagggcatcagagaaa gtgaaagatctaggtaacatagaaacggtcaccatacggagattgcatattccaaagttc ttcttattttatgacctgagcaccgtgtattcacttgcaaaaactgtaaagcgagtcaca gtagaaaacagtaaggtttttctggttccttgttccttttcacgacatttaaaatcatta gaatacttggatctcagtgaaaatttgatggttgaagaatacttgaagaattcagcgtgt gaagatggctggccctccctacaaaccttaattttaaggcaaaatcatttgacattcata gaaaaaactgcagaggttttgctgactctgaaaaacctgacagaccttgacgtcagtaag aatagttttcattttatgccggaaacttgtcagtggccaaaaaagatgaggtacttgaat ttatctagcacacgaatacagagtttaacctcttgccttccccagacactggaagtttta gatgttgacaataacaatcttaattcatttactttacttttgcctcaactcaaagaactt tatatttccagaaataagttgaagactctcccagatgcctccttcttacctgtgttacta gtcatgaaagtcagaaagaatacaataaatactttctctaaggagcaacttgattctttt caccacctgaagagtctagaagcaggtggcaacaacttcgtctgctcttgtgaactcctc tctttcacacaggagcagccagcactggccaaggtcctgatcgactggccagacaactac ctgtgtgactctccagcccacgtgcggggccagagggttcaggatgcccggctgtccgcc tctgagtgctacaaggcagcactagtgtcaggtgtgtgcggtatccttgtcctattgatc ctgctcatcgtgggcctgtgccaccgtttccatggactgtggtatgtgagaatgatgtgg gcttggctccaggccaagaggaagcccaggaaagccccaggcagggacgtctgctatgac gcctttgtttcctacagtgagcacgattcctactgggtggaaaacctcctggtgcaggag ctggagaacttggatccccccttcaagctgtgcctccacaagcgggattttgttcctggc aagtggatcattgacaatatcattgactgcatcgaaaagagccacaaaactgtctttgtc ctgtcagagaactttgtgaggagcgagtggtgcaagtatgaacttgacttctcccatttc cggctcttcgatgagaacaacgacgctgctatcctcgttctcctggagcccatcgagaaa aaagccatccctcagcgcttctgtaggctgcggaagatcatgaacaccaagacctacctg gagtggcccagggatgaggctcagcaggaagggttttgggtcaatttgagaactgcgata aagtcctaa

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