Castor canadensis (American beaver): 109702407 Help Entry 109702407         CDS       T04791                                  Symbol Fasn Name (RefSeq) fatty acid synthase   KO K00665   fatty acid synthase, animal type [EC:2.3.1.85] Organism ccan  Castor canadensis (American beaver) Pathway ccan00061   Fatty acid biosynthesis ccan01100   Metabolic pathways ccan01212   Fatty acid metabolism ccan04152   AMPK signaling pathway ccan04910   Insulin signaling pathway ccan04936   Alcoholic liver disease Module ccan_M00082   Fatty acid biosynthesis, initiation ccan_M00083   Fatty acid biosynthesis, elongation Brite KEGG Orthology (KO) [BR:ccan00001]  09100 Metabolism   09103 Lipid metabolism    00061 Fatty acid biosynthesis     109702407 (Fasn)  09130 Environmental Information Processing   09132 Signal transduction    04152 AMPK signaling pathway     109702407 (Fasn)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     109702407 (Fasn)  09160 Human Diseases   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     109702407 (Fasn)  09180 Brite Hierarchies   09181 Protein families: metabolism    01004 Lipid biosynthesis proteins [BR:ccan01004]     109702407 (Fasn)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:ccan04147]     109702407 (Fasn) Enzymes [BR:ccan01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.85  fatty-acid synthase system      109702407 (Fasn) Lipid biosynthesis proteins [BR:ccan01004]  Fatty acid synthase   Animal type    109702407 (Fasn) Exosome [BR:ccan04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    109702407 (Fasn)   Exosomal proteins of breast milk    109702407 (Fasn)   Exosomal proteins of colorectal cancer cells    109702407 (Fasn)   Exosomal proteins of bladder cancer cells    109702407 (Fasn) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Acyl_transf_1 ketoacyl-synt Thioesterase KR KAsynt_C_assoc FAS_pseudo-KR Ketoacyl-synt_C ADH_zinc_N_2 ADH_zinc_N PKS_DH_N PP-binding adh_short Methyltransf_12 Methyltransf_23 Thiolase_N Methyltransf_31 PS-DH ACP_SdgA_C Methyltransf_11 ACP_syn_III Motif Other DBs NCBI-GeneID:  109702407 NCBI-ProteinID:  XP_020043349 UniProt:  A0A8B7WI96 LinkDB All DBs Position Unknown AA seq 2505 aa AA seqDB search MEEVVIAGMSGKLPESENLEEFWANLINGVDMVTDDDRRWKAGLYGLPRRAGKLKDLSKF DASFFGVHPKQAHTMDPQLRLLLEVAYEAIVDGGINPASLRGTHTGVWVGVSGSEASEAL SRDPETLLGYSMVGCQRAMMANRLSFFFDFKGPSIALDTACSSSLLALQNAYQAIRSGEC PAALVGGINVLLKPNTSVQFMKLGMLSSEGTCKSFDSAGDGYCRAEAVVAVLLTKKSLAR RVYATVLNAGTNTDGCKEQGVTFPSGEAQEVLIRSLYQPGGVAPESLEYIEAHGTGTKVG DPQELNGIVRALCTSRQDPLLIGSTKSNMGHPEPASGLAALSKVLLSLEHGLWAPNLHYH SPNPEIPALSDGRLQVVDQPLPIRGGNVGINSFGFGGSNVHVILQPNTQPPPAPAPHGTL PRLLRASGRTAEAVQTLLEQGLRHSQDLAFVSMLNDIAATPVAAMPFRGYAVLSVEDSGQ EVQQVSSGERPLWFICSGMGTQWHGMGLSLMRLGGFRDSILRSDEALKPFGVKVSGLLLS TDESTFDDIVHAFVGLTAIQIALIDLLTSVGLRPDGIIGHSLGEVACGYADGCLSQEEAV LAAYWRGQCIKEAHLPAGSMAAVGLTWEECKQRCPPGIVPACHNSEDTVTISGPQAAMTE FVEQLKQEGVFAREVRTGGIAFHSYFMDAIAPTLLQALKKVIREPRPRSARWFSTSIPEA QWQGELARTSSAEYNVNNLVSPVLFQEALWHIPEHAVVLEIAPHALLRAVLKRGVKPSCT IIPLMKKDHKDNLEFFLTNLGKLHLTGIDVNPNALFPPVEFPAPRGTPLISPHIKWDHSQ TWDVPASEDFPNGSSSSSATVYTIDASSESPDHYLVDHRIDGRVIFPATGYLCLVWRTLA RALGLALEQTPVVFEDVTLHQATILPKTGTMLLEVRLLEASHTFEVSENGNLIVSGQVYQ WESPDPKFFDHPEDLSPATPTSASFLAQADIYKELRLRGYDYGLHFQGVLEASLEGDSGK LLWKNNWVSFLDTMLQMSILGMSQRSLRLPTRIAAIHIDPAAHLQKVYALQGTQVANVVV NHCLSMTVAGGARISRLHTSVAPRRQQEQMVPILEKFCFTPHVEVGCLSESTTLQEELQL CKGLIQALQSKAAQQGLKMAVPGLDAAQALRESPQQGLPQLLAAACQLQLNGNLQLELGQ TLAQEKVLLSEDPLVCGLLNSQALKAYVDTALENLPSLKIKVVEVLAGEGHLYSRIPALL NTQPMMQLDYTATDRYLEATQAKLQQHGIAQSQWDPMDPAPSSLSAADLLVCNCALATLG DPALALANMVAALKEGGFLLLHTVLRGHTLGDTLAFVTSEPQHGPSLLTQDEWENLFLRT SLHLVGLKKSFYGSVLFLCRRPAPRESPIFLPVEDTSFRWVDSLKNILTESSSQPVWLTA VDCPTSGVVGLVNCLRKEPGGHRIRCILLSNLSSASHIPKMEPNSAELQKVLADDLVMNI YRDGAWGAFRHFPLEQDKPEEQTAHAFVNVLTRGDLASIRWVCSPLRHAQPSSPREQLCT VYYASLNFRDIMLATGKLSPDAIPGKWATRDCMLGMEFSGRDARGRRVMGLVPAEGLATS VLLSPDFLWDVPSSWTLEEAASVPVVYTTAYYALVVRGRVRHRETVLIHSGSGGVGQAAI AIALSLGCRVFTTVGSAEKRAYLQARFPQLEDTSFANSRDTSFEQHVLRHTGGKGVDLVL NSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHPLGMAIFLKNVTFHGILLDALFEEASA DWREVAALLQSGIRDGVVQPLKCTVFPKAQVEDAFRYMAQGKHIGKVLIQVREEELEAVL PGAQPTLMSAISKTFCPAHKSYVITGGLGGFGLELAQWLTLRGAQRLVLTSRSGIRTGYQ AKQVHEWRRQGLQVLVSTSDASSLEGARALIAEAAQLGPVGGIFNLAMVLRDAMLENQNP ELFQDVNKPKYSGTLNLDRVTREACPELDYFVAFSSVSCGRGNAGQSNYGFANSTMERIC EQRRHDGLPGLAVQWGAIGDVGIVLEAMGTNDTVIGGTLPQRITSCLEVLDLFLNQPHAV LSSFVLAEKTVSRGDGEGQQDLVKAVAHILGIRDLAGINLDSSLADLGLDSLMGVEVRQT LEREHDLVLSMREVRQLTLRKLQELSSKTAGATDLTDPKAQNSPAWQQAQLNLSSLLVNP EGPTLMRLNSVQSSERPLFLVHPIEGSTTVFHSLAAKLSMPTYGLQCTRAAPLDSIQSLA AYYVDCIRQVQPEGPYRVAGYSYGACVAFEMCSQLQAQQGPTPTHNSLFLFDGSHAYVLA YTQSYRAKMTSGCEAEAEAEAICFFVQQFTDVEHSRVLETLLPLKGLEERVAAAVDFITK SHQGLDPQKLSFAVLSFYHKLRAAEQYMPKSKYHGNVTLLRAKTGGAYGENLGADYNLSQ VCDGKVSVHVIEGDHRTLLEGQGLESIISIIHSSLAEPRVSVREG NT seq 7518 nt NT seq  +upstreamnt  +downstreamnt atggaggaagttgtgattgccggcatgtccgggaagctgcctgaatctgagaacctggag gagttctgggctaacctcatcaatggtgtggacatggtcacagatgatgaccggcggtgg aaggcggggctctatgggctgcccagacgggctggcaagctgaaggacctatccaagttc gacgcctccttctttggggtacaccccaaacaggctcacacaatggatccccagctccgg ctgctcctggaggttgcctatgaggccatcgtggatggaggcatcaacccggcctcgctc cgaggaacgcacactggcgtctgggtgggtgtgagtggctccgaggcttcggaggccctg agccgagatcctgagaccctcttgggctacagcatggtgggctgccagcgggcaatgatg gccaaccggctctctttcttctttgacttcaaagggcccagcattgccctggacacagcc tgctcctccagcttgctggcgctacagaatgcttaccaggccatccgcagtggggagtgc cccgctgccctcgtgggcggcatcaacgtgcttctgaagcccaacacgtctgtgcagttc atgaagctgggcatgctcagctctgagggcacctgcaagtctttcgacagcgcgggggat gggtattgccgtgcagaggccgtggtggccgtcctgctgaccaagaagtctctggcccgg cgggtgtatgccactgtcctgaatgctggcaccaatacagacggttgcaaggaacaaggt gtgaccttcccctctggggaggcccaggaggtgctcatccgctccctgtaccagccgggc ggtgtggcccccgagtccctggagtacattgaagcccatggtacaggcaccaaggtgggc gacccccaggaactgaacggcatcgtccgggccctgtgtacctcccgccaagaccctctg ttaattgggtccaccaagtccaacatggggcaccccgaacctgcatccgggctcgcggcc ttatccaaagtgctgctgtccctggagcatgggctctgggcccccaacctgcactaccac agccccaaccctgagatcccagccctgagtgatgggcggctgcaggtggtagaccagccc ctgcccatccgtggtggcaatgtgggcatcaactcctttggctttggaggctccaatgtg cacgtcattctccaacccaacacacagccaccgcctgcacctgccccccacggcaccctg ccccgtctgctgcgggccagtggacgcaccgcagaagccgtgcagaccctgctggagcag ggcctgcggcacagccaggacttggccttcgtgagcatgctcaatgacattgcagccacc cctgtggccgccatgcccttcaggggctatgcggtgctgagtgttgaggacagtggccag gaagtacagcaggtgtcctctggcgagcgcccactctggttcatctgctccggcatgggc acccagtggcacgggatggggctcagcctcatgcgcctgggcggcttccgcgactccatc ctgcgctctgacgaggccttgaagccgtttggagtgaaggtgtccggcctgctgctgagc acagatgagagcacctttgatgacattgtgcatgcctttgtgggcctcacggccatccag attgctctcatagacctgctgacctctgtgggcctgagacctgatggcatcattgggcac tccctgggggaggtggcctgtggctatgccgatggctgtctttcccaggaggaggctgta cttgcagcctactggagaggccagtgcatcaaggaggcccacctccctgctggctccatg gcagctgtgggcttgacctgggaggagtgtaaacagcgctgcccccctggcatcgtgcct gcctgccacaactctgaagacacagtgaccatctccggacctcaggccgccatgactgag ttcgtggagcagctaaagcaggagggtgtgtttgccagggaggtgcgaaccgggggcatc gcttttcactcctacttcatggacgccattgccccgacgctactgcaggctctcaaaaag gtgatccgggagccgcggcctcgctcagctcgctggttcagcacctccatccctgaggct caatggcagggcgagctggcccgcacgtcctcagccgagtacaacgtcaacaacttggtg agccctgtgctcttccaagaggctttgtggcacatccctgagcatgcagtggtgctggag atcgcgccccatgccctgctgcgggctgtcctgaagcggggtgtgaagccgagctgtacc atcatcccgctgatgaagaaagaccataaggacaacttggagttcttcctcaccaacctt ggcaagctgcacctcacaggcatcgatgtcaaccctaatgccttgttcccgcctgtggag ttcccggctcctcgaggtacccctctcatctccccccatatcaagtgggaccacagtcag acctgggatgtgccagcttcagaggacttccccaatggttccagctcctcgtctgccacc gtctacaccatcgatgccagctccgagtctcctgaccactacctggtggaccaccgcatc gatggccgtgtcatcttccctgccactggctacctttgcctggtgtggaggacactggct cgtgccctgggtctggccctggagcagacacctgtagtgtttgaggatgtgacactacac caggccaccatcctgcccaagacagggaccatgctgctggaggtgcggctgctggaggcc tcccacaccttcgaggtgtctgagaatggcaatctgatagtgagcgggcaagtgtaccag tgggagagccccgatcctaagttctttgaccatcctgaagacctgagccctgccacgcct acatccgcctccttcttggctcaggctgacatatacaaggagctgcggctgcgtggctat gactatggcctccacttccagggtgtccttgaggccagcctcgaaggtgactcaggcaag ctgctctggaagaacaactgggtgagcttcctggacacgatgctgcagatgtccatcctg ggcatgagccagcgcagtctgcgcctgcccacccgcattgctgccattcacattgaccct gccgcccatctgcagaaggtgtatgcactgcagggcacccaagtggccaacgtggtggtg aaccattgtctgagcatgacggtggctggtggtgcccgcatctcacggctacacacgtcg gtggccccacggcggcagcaggagcagatggtgcccatcctggagaagttctgtttcaca ccccacgtggaggtcgggtgcctgtctgagagcaccaccctgcaggaggaactgcagcta tgcaagggactgatacaggcactgcagagcaaggcagcacagcaggggctgaagatggca gtgcctgggctggatgcagcccaggccctccgggagtccccacagcaagggctgccccag ctgcttgcggctgcctgccagctgcaactcaatgggaacctgcagctggagctgggacag acactggcccaggagaaagtcttgctgtcggaggaccccctagtctgtgggctcctcaac tcccaggcactcaaggcctatgtggacacagccctggagaacctgcccagcctcaagata aaggtggtagaggtgctggctggcgagggtcacctgtattcccgcatcccggcattgctc aacacccagcccatgatgcagctggactacacagccactgaccgctatctggaggccacc caggccaagctgcagcaacatggcattgcccagagccagtgggaccccatggaccctgcc cctagcagcctgagtgcagctgacctcctggtgtgcaactgtgcattggccaccctgggg gacccagccttggccctagccaacatggtagctgccctcaaggagggtggcttcctgctg ctgcacaccgtgctcagagggcacacccttggggatactctggcctttgtcacctccgag ccacagcacgggcccagcctcctgactcaggatgagtgggagaatctgtttttgaggaca tcgctgcaccttgtgggcctgaagaagtcgttctatggttctgtgctcttcctgtgccgc cggcctgccccacgggagagccccatcttcctgcctgtggaggataccagcttccgatgg gtggactctctaaagaacattctgactgagtcgtcttctcagcctgtgtggctaacagca gtggactgccccacctcaggtgtggtgggcttggtgaactgtctccgcaaagagcctggt gggcaccggattcggtgcatcctgctgtccaacctcagcagtgcctcacacatccccaag atggaacccaactctgcagagctgcagaaagtgctggcagacgacctggtgatgaacata tatcgcgatggagcctggggtgcctttcgccactttcccctggagcaggacaagcctgag gagcagaccgcacacgctttcgtgaatgtcctcacccggggagaccttgcctccatccgc tgggtctgctctcctctgagacatgcccaaccctccagccccagggagcagctctgcact gtctactacgcctcactcaacttccgagacatcatgctagccacgggcaaactgtcccct gatgccatcccagggaaatgggccacgcgggactgcatgctgggcatggagttctcaggc cgtgacgcccggggccggcgtgtgatgggtctggtgcctgctgaaggcctggccacctca gtcctgctgtcacctgacttcctctgggatgtgccctccagctggaccctggaggaagca gcttctgtgcctgtcgtctacaccaccgcctattatgcactggtggtgcgcggacgggtg cggcacagggagacggtgctcatccactcaggctcggggggtgtgggccaggccgccatc gccattgccctcagccttggctgccgcgtcttcaccactgtgggctctgctgagaagcgg gcatacctccaagccaggttcccccagctcgaggacaccagctttgccaactcccgggac acgtcgtttgagcagcacgtgcttcggcacacgggtggcaagggcgtcgacctggtcctc aactccctcgcggaagagaagcttcaggccagtgtgaggtgcctggctcagcatggccgc ttcctggagatcgggaaatttgacctttctaacaaccatccactgggcatggccatcttc ctgaagaatgtcaccttccatgggatcctgctggatgcgctcttcgaggaggccagtgct gactggcgggaagtggcggcactgcttcagtctggcatccgtgacggggtggtgcagccc ctcaagtgcactgtattccccaaggcccaggtggaggatgccttccgctacatggcccag gggaagcacatcggcaaagtcctcatccaggtgcgtgaggaggagctggaggccgtgctg ccaggggcacagcccaccttgatgtctgccatctccaagaccttctgccccgcccacaag agctatgtcatcactggtggcctgggcggctttggccttgagctggcccagtggctcacg ctgcggggggcccagaggctggtgctgacctctcgctcaggaatccgcacaggctaccag gccaaacaggtccatgagtggaggcggcagggcttgcaagtgctggtatccaccagtgat gccagctcactggagggggcccgagccctcattgctgaggcagcacagctcgggcctgtc ggcggcatcttcaacctggccatggttttgagagatgccatgctagagaaccagaaccca gagctcttccaggatgtcaacaagcccaagtacagtggcaccctgaacctggacagggta acccgggaagcctgccccgagctggactactttgtggccttctcctcagtgagctgtgga cgcggcaacgccggccagagtaactatgggtttgccaactccaccatggagcgcatatgc gagcagcgtcggcatgatggcctcccaggcctcgccgtgcagtggggtgccattggtgac gtgggcattgttctggaggcaatgggcactaatgacacagtcatcggcggcacattgcca cagcgcatcacctcctgcctggaagtgctggacctcttcctgaaccagccccatgctgtc ctgagcagcttcgtgctggctgagaagactgtgtcccgtggggatggcgaagggcagcag gacctggtgaaggccgtggcacacatcctgggcatccgtgacctggcaggtatcaacctg gacagttcactggcagacctgggcctggattcgctcatgggcgtggaggtacgccagaca ctggagcgcgagcatgatctggtgctgtccatgcgtgaggtgaggcagctcacacttcgg aagctacaggagctgtcctccaaaactgctggggccaccgatctgacggaccccaaagcc cagaacagtccagcctggcagcaggcccagctgaacctgagctccctgctggtaaaccct gagggtcccactctgatgcggctgaactctgtgcagagctctgaacggccactgttccta gtgcacccaattgagggctctactaccgtgtttcacagcctggccgccaagctcagcatg cccacctatggcctacagtgcacccgagccgcaccgctggacagcattcagagcctggct gcctactacgtcgactgcatcaggcaggtgcagcccgaggggccctaccgcgtggctgga tactcctatggtgcctgcgtggcttttgagatgtgctcccagctgcaggcccagcagggc ccgacccccacccacaacagcctcttcctgtttgatggctcacacgcctatgtgctagcc tacacccagagctaccgtgctaagatgacatcaggctgcgaggccgaggccgaggccgag gctatatgcttctttgtgcaacagttcactgacgtagagcacagcagggtgctagagacc ctgctaccgctgaagggcttggaagagcgtgtagctgctgctgtggacttcattaccaag agccaccagggcctggacccccaaaagctgagttttgctgtcctgtccttttaccacaag ctgcgtgcagctgagcagtacatgcctaagtccaagtaccatggcaacgtgacgcttctg cgagccaagacaggtggtgcctatggcgagaacctgggtgctgactacaacctctcccag gtgtgtgacggaaaggtatctgtgcatgtaatcgagggtgaccaccgcacgttgctggag ggccaaggcttggagtccattatcagtatcatccacagctccctggctgagccacgtgtg agtgtgcgggagggctag

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