Caretta caretta (Loggerhead turtle): 125622274
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Entry
125622274 CDS
T09292
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
ccay
Caretta caretta (Loggerhead turtle)
Pathway
ccay00140
Steroid hormone biosynthesis
ccay01100
Metabolic pathways
Module
ccay_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
ccay_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
ccay_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
ccay_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
ccay00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
125622274
Enzymes [BR:
ccay01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
125622274
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
125622274
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Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
NmrA
KR
Ldh_1_N
Motif
Other DBs
NCBI-GeneID:
125622274
NCBI-ProteinID:
XP_048676122
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Position
1:204334143..204354182
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AA seq
377 aa
AA seq
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MSLAGVSCLVTGASGFLGQRIVHLLLEEEKELAEIRTLDIAFSDEARMNFTNFKGQTVVK
ILEGDIRDATFLNSACEGVSLVIHTASIIDTLGLVEKQLLWEVNVTGTQLLLDACVRSNV
QHFIYTSTIEVIGPNCRGDPICNGDEDTAYQSTSGFPYAQSKRLAETSVLKANGQALKDG
GIFLTCALRSMYIFGEGCRFLQTHLDKSLLNKNVYLRISRKDALVNPVYVGNIAWAHIQV
AKALRNPERAKHVKGHFYYISDDTPHMSYADLNYELTKELGFGIEPHPPMPLMMLYYFAL
LLEVVSFLLRPFVKYIPSTNRHLVILLNTQFTFSYRKAWRDFGYMPRYKWKEAKQRTSQW
IASLIPQRRAYLKHKAV
NT seq
1134 nt
NT seq
+upstream
nt +downstream
nt
atgtctttggctggggtgagctgtctggtgacaggagcaagtggatttcttggccagaga
attgtccacttactgctggaggaggagaaggagctggctgagatccgaaccctggacata
gcctttagcgacgaggcacgcatgaattttacaaatttcaagggtcagactgtggtgaag
atcttggaaggggacatccgggatgctacattcttgaacagcgcctgcgagggtgtctcc
cttgtcatccatacagcatccatcattgacaccttgggccttgtagagaagcagctgctc
tgggaagtcaatgtaacaggtacccagctactgctggatgcctgtgtccgcagtaatgtc
cagcacttcatctacaccagtaccatagaagtcataggcccaaactgcagaggggacccc
atctgcaatggggatgaagatacagcctaccagagcacatcaggatttccttatgcccag
agtaagagactggcagagacgtctgttctgaaggcaaatggtcaggcactgaaggatggt
ggcatcttcctgacgtgtgccttgaggtccatgtacatctttggagaaggatgccggttt
ctccagactcacctggataaaagcctcttgaataaaaatgtctacctgcggatttctagg
aaagacgctctggtgaatcctgtatatgtgggaaacattgcatgggctcacatccaggtg
gcaaaagccttgaggaacccggaaagagccaagcacgtcaaagggcacttctactatatc
tctgatgacactcctcacatgagctatgccgacctaaattatgagctgaccaaggagctg
gggtttggaattgagccccacccacccatgccgctgatgatgctgtactactttgcgctt
ctgctagaagttgtgagcttcctacttaggccctttgtcaaatacatcccctccaccaac
cgtcaccttgtgatcttgctgaacacgcagttcacgttctcctacaggaaggcatggcgg
gattttggctacatgccccgctacaaatggaaagaggccaagcagcgcaccagccagtgg
attgcctcactgattccacaaaggagggcgtacctgaaacacaaggctgtctaa
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