KEGG   Coregonus clupeaformis (lake whitefish): 121533863
Entry
121533863         CDS       T08357                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 isoform X1
  KO
K01116  phosphatidylinositol phospholipase C, gamma-1 [EC:3.1.4.11]
Organism
cclu  Coregonus clupeaformis (lake whitefish)
Pathway
cclu00562  Inositol phosphate metabolism
cclu01100  Metabolic pathways
cclu04012  ErbB signaling pathway
cclu04020  Calcium signaling pathway
cclu04070  Phosphatidylinositol signaling system
cclu04370  VEGF signaling pathway
Module
cclu_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cclu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    121533863
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    121533863
   04370 VEGF signaling pathway
    121533863
   04020 Calcium signaling pathway
    121533863
   04070 Phosphatidylinositol signaling system
    121533863
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cclu04131]
    121533863
Enzymes [BR:cclu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     121533863
Membrane trafficking [BR:cclu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    121533863
 Endocytosis
  Macropinocytosis
   Phospholipase C
    121533863
SSDB
Motif
Pfam: PI-PLC-X SH2 PI-PLC-Y EF-hand_PLCG2 C2 SH3_1 PH EF-hand_PLCG1 SH3_9 PH_12 SH2_1 EF-hand_6 SH3_2 EF-hand_7 EF-hand_9 GDPD
Other DBs
NCBI-GeneID: 121533863
NCBI-ProteinID: XP_041696105
LinkDB
Position
20:complement(30902016..30954869)
AA seq 1325 aa
MCAARFSSSNSVNGCGGVGDRDETTTNGPGTGPGTASRMLDWSEAGTRILHSLEIGTVMT
VFYQKKSQRPERRTFQIRQDTRQIVWSRNPDKIEGEIDIREIRELRLGKGSRDFERYPEE
ARKLDSTHCFIVLYGLEFRLKTLSVAAFSEEEVNMWITGLNWLMMDTQRASAPQQIDRWL
RRQFEVMDRNREGSITVKDVKALLPQINYRVPNMRFLKDKLQEVEARCDLSFPHFSQLYR
TLMFDAQRSIIEQLELSFPLRNVDRPELCQISLYDFQKFLQLDQKESWASDMSRVREFLM
GYLRGGAQTEPMLQLDEFLTFLYSKENSLCDPRPAAVVSDDMKRPLSQYWISSSHNTYLT
GDQFSSESSLEAYARCLRMGCRCIELDCWDGPDDLPIIYHGHTLTSKIKFLDVLHTIKEH
AFVTSEYPVILSIEDHCSVVQQRNMATHFKKVFGDLLLTKPVDLNADELPSPYQLRRKIL
IKHKKLVEGTLYEEVTSASYSESDISNSLRNGILYLEDPIDHTWTPHYFVLSSNKIYYSE
ETSHYQTAEEEEEEEMEEEGGKEECNNNEQHCAERWFHGKLGGGRDGRQVAEKLLQEYCE
GGGKDGTFLVRESETFVGDYTLSFWRSGRVQHCRIHSRQESGSTRYYLTDNLVFDSLYRL
ICHYRDTPLRCNEFEMRLGSPVPQPNAHESREWFHSSLSRVQAEHMLMRVPRDGAYLLRK
RSDINSYAISFRAEGKIKHCRIQQEGRMFMLGSSAEFESLVDLVSYYEKHPLYRKMRLRY
PINEDTLDRMGTTELDYGALYEVRTPHFYVEANKMPTARCTVKALYDYRAQREDELCFPK
QALILSVDKQEGGWWRGDYGGKKQLWFPANYVEEVPNSPARETGDEASTENSPLGTFLKG
FIDVPTCHVVVQKDGKSSRPYVFTIHSQQMSIHPGQALDIASDTLEDLTGWVGKIREATQ
NADARMQEEKQMERRKKIALELSELVVYCRPVPFNEEKIGTERTCFRDMSSFPETKAEKF
ATRARGKRFLQYNRRQLSRVYPRGQRLDSSNYDPLPMWLCGSQLVALNFQTPDKPMQLNQ
ALFMLGGGSGFVPQPDIMRDDTFDPFDKDTLRLEPITIQLQVLGARHLPKNGRSIVCPFV
EVEVCGADYDCSKSKTDVVADNGLNPVWVQRQFVFDVHNPSFSFLRFLVYEEDMFSDPNF
LAQAIYPVRSLRTGYRSVPLKNSYSEELELASLLVHIEIVNAKEEDDENLYSSIQRLRDR
TSELSNQVSVLERAGSGGDHSYQQSLEELRAAQDQLSELVETRNHRLIEKKKREKLRQQV
GAKRN
NT seq 3978 nt   +upstreamnt  +downstreamnt
atgtgtgctgccaggtttagtagcagcaatagtgtcaatggctgtgggggggttggggac
cgggatgagaccaccactaatggccccggtacaggcccgggcaccgcatcccgcatgctg
gactggtccgaggcgggcacccgcattctccacagcctggagattggaacggtcatgact
gtgttctaccagaagaagtcccaacgaccggagaggaggaccttccagatacgacaggac
actagacagatagtgtggagccgcaaccctgacaagatagagggagagattgacatcagg
gagatcagagagctgcggttgggtaaaggctcccgggactttgagcgttatccagaggag
gctcgtaaattagactccacccactgcttcatcgtgctctacggactggagttccgtctc
aaaacactcagcgtggctgcctttagtgaggaggaggtcaatatgtggatcactggactc
aactggctgatgatggatactcagagagcctcagcaccacaacagatagacaggtggctg
aggagacagtttgaggtgatggacaggaatcgggagggaagtatcacagtaaaggatgtg
aaggccctgttacctcagatcaactacagagtccccaacatgcgcttcctcaaagacaag
ctacaggaagtggaagccaggtgtgatctctccttccctcacttttctcagctctacaga
acattgatgttcgacgcacagaggagtatcattgagcagctggagctctccttccccctc
cggaacgtggacagaccagagctgtgtcagatctctttgtacgacttccagaagtttcta
cagctggatcagaaggagtcatgggcgtcggacatgagccgcgtcagagagttcctaatg
ggctacctgaggggtggagcacagaccgaacctatgctacagctagatgagttcctgacg
ttcctgtactccaaggagaactcattgtgtgaccctcgacctgctgctgttgtctctgac
gacatgaagagacccctgtctcagtactggatctcctcatcacacaacacgtatctgaca
ggtgatcagttctccagtgagtcatctctagaggcctacgctcgctgcctaaggatgggc
tgtcgctgcatagaacttgattgctgggatgggcccgatgacctgccaatcatctaccat
ggccacaccctcacctccaagatcaaattcctggacgtgctgcacaccatcaaagagcat
gcctttgtcacgtcagagtacccagtgatcctgtccatagaggaccactgtagtgtggtc
caacaaaggaacatggctactcactttaagaaggtgtttggggatctgctgctgaccaaa
ccagtggatctgaatgcagatgagctgccatcgccctaccagctacgcaggaagatactc
atcaagcataagaaactagtggagggcactctgtatgaagaggtgacgtcagccagctac
tctgagagtgacatcagtaactccctcaggaatggcattctctacctggaagaccccata
gaccacacgtggactccccactactttgttctgagcagtaataagatctactactcagag
gagacctctcactaccagactgccgaggaagaggaggaggaggagatggaagaggagggg
gggaaagaggagtgtaacaacaatgagcaacactgtgcggagcgctggttccatgggaag
ctgggaggggggcgggatgggaggcaggttgccgagaaactgctgcaggagtactgtgag
ggcgggggcaaggatgggaccttcctggttcgagagagtgagaccttcgtaggagactac
actctctccttctggcgatctgggcgtgtgcagcactgtaggatccactcccgccaggag
tctggctccacccgctactacctgactgacaacttggtgtttgacagcctgtatagactc
atctgccactacagagacactcccctacgctgcaacgagtttgagatgaggctgggcagc
cctgtaccacagcccaatgcacacgagagcagagagtggttccactccagtctgtctcgt
gtccaggctgaacacatgttgatgagggtacccagagacggagcctacctgctccgcaaa
cgcagcgacatcaactcctatgctatctccttcagggcggagggtaagatcaaacactgt
cgtatccagcaggagggacgaatgttcatgttgggtagctcagcagagtttgagagtctg
gttgacctggtcagctactatgagaaacaccccctgtaccgcaagatgaggctgcgctac
cccatcaacgaagacacactggaccgcatgggcaccacggagctagactatggagcgttg
tatgaagtcaggaccccacatttctacgtcgaggccaacaagatgcccacggctcggtgt
acggtcaaggccctgtatgactacagagcccagagggaagacgagctgtgtttccccaaa
caggccctcatcctaagtgtggacaagcaggaaggaggctggtggcgaggtgattacgga
gggaagaagcagctgtggtttcctgccaactacgtagaagaagtccccaactcacccgcc
cgcgagacaggagatgaggcatctacagagaacagtccactaggaacattcctcaagggc
ttcattgatgtgcccacctgccacgtagtggttcagaaggatgggaagagttccaggcca
tatgtgttcaccatccactcccagcagatgtcaattcaccctggccaggcgctggacatt
gcttcagacaccctggaggacctgaccggttgggtggggaagatcagagaggccacacag
aacgcagacgcacggatgcaggaagagaagcagatggagaggaggaagaagatcgctctg
gagctctctgagttggtggtctactgtagacctgtccccttcaacgaagagaagatcggg
acagagcggacatgtttccgggatatgtcatcattccctgagaccaaggcagagaagttt
gccacgcgtgcaagagggaaacgcttcctgcagtataaccgccgccagctctcccgggtc
tacccccgaggacagagactagactcctctaactacgaccctttacccatgtggctctgt
ggatcccagctggtcgctctcaacttccagacacctgacaagcccatgcagttgaaccag
gctctgttcatgctgggtggggggagtggcttcgtgccccagcctgacatcatgagggat
gacacctttgaccccttcgacaaggacaccctccgcctggagccaatcaccatccagcta
caggtactgggagctcgtcacctccctaagaatggccgcagtatagtgtgtccctttgta
gaggttgaggtgtgtggggccgactacgactgcagcaagagcaagaccgacgttgtggct
gacaatgggttgaacccagtgtgggttcagaggcagtttgtgtttgacgtccataacccg
tccttctcctttctgcgcttcttggtctatgaggaggacatgttctctgaccccaacttc
ctggctcaggccatctaccctgtccgctcactaagaacaggctacaggagtgttccactg
aagaacagttacagtgaagagttggagctggcttctctgctggttcacattgagattgtc
aacgccaaggaggaagatgatgagaacctgtactcgtccatccaaaggctgagagaccgc
accagtgagctgtccaatcaggtgtcagttctggagagagcggggtcaggaggtgaccac
agctaccagcagagtctggaggagctgagagcagcacaagatcagctcagtgagctagtg
gagacacgcaaccacaggctgattgagaagaagaagagggagaagctgaggcagcaggtg
ggggctaagcgcaactaa

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