Coregonus clupeaformis (lake whitefish): 121536290
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Entry
121536290 CDS
T08357
Symbol
hsd3b1
Name
(RefSeq) hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
cclu
Coregonus clupeaformis (lake whitefish)
Pathway
cclu00140
Steroid hormone biosynthesis
cclu01100
Metabolic pathways
Module
cclu_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
cclu_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
cclu_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
cclu00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
121536290 (hsd3b1)
Enzymes [BR:
cclu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
121536290 (hsd3b1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
121536290 (hsd3b1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
NmrA
KR
RmlD_sub_bind
Motif
Other DBs
NCBI-GeneID:
121536290
NCBI-ProteinID:
XP_041699488
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Position
23:33497082..33498812
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AA seq
374 aa
AA seq
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MSLQGDVCVVTGACGFLGERLVRLLMEEEKLTEIRMLDIHVRPQHIQCLEEVRGDTLVSV
FEGDIRDSELLRRACKGASLVFHTASLIDVTGKVDYGELHRVNVKGTQLLLETCVQENVM
SFIYTSSIEVAGPNANGDPIINGDENTPYTCSLKFPYSRTKKEAERVTLQAQGEVLQNGG
RLATCALRPMYIYGEGCRFLLGHMGDGIRNGDMLYRTSRPEAQVNPVYVGNAALAHLQAA
RALRDPQRRAAIGGNFYYISDDTPPVSYSDFNHVVLSPLGFSIQEKPILPIPVLYLICFL
MEMLQMLLRPFKRFTPPINRQLLTMLNTPFSFSYRRAQRDMGYTPRYSWEEARKRTMDWV
ASQLPKERERIKAK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgcaaggcgatgtgtgtgtggtgacaggagcctgtgggttcctgggggagagg
ctggtccggctgctaatggaggaagagaagctcacagagatccgtatgctggacatacat
gtccgaccacaacacatacagtgtctggaagaggtcagaggggacacgctggtgagtgta
tttgagggggacatcagggatagtgaactgctgaggagagcgtgcaagggtgcatcgctg
gtcttccacaccgcgtccctcatagacgtcaccgggaaggtggactacggtgagcttcac
agggtcaacgtcaaaggaacccagctccttctggagacgtgcgtccaggagaatgtgatg
tcctttatctacaccagcagcatcgaggtggcaggccccaacgccaacggagaccccatc
atcaacggtgatgagaataccccctacacatgctccctaaagttcccctacagcaggacc
aagaaggaggcagaacgggtcaccctgcaagcccagggtgaggtgctccagaatgggggc
cggctggccacctgcgccctccgacccatgtacatctatggagagggctgccgcttcctg
ctgggccacatgggagacgggattcgtaacggggacatgttgtaccgtacctcccgtccg
gaggcccaggtgaaccctgtatacgtggggaatgcggccctggcccacctccaggccgcc
cgcgccctgcgagacccccagcggagagccgccattggagggaacttctactacatctca
gatgacacgcctcccgtcagctactctgacttcaaccatgttgtgttgtcgccgctgggc
ttcagcatccaggagaagcctatcctgcccatcccagtcctctacctcatctgtttcctc
atggagatgctgcagatgctgctccgccccttcaagcgcttcaccccgcccataaaccgg
cagctccttaccatgctgaacacacccttcagcttctcctatcggagggctcagagggac
atggggtacaccccgcggtacagctgggaggaggcacgcaagcggaccatggattgggtg
gcttcccagttacccaaggagcgagagcgaataaaggctaaataa
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