Crocuta crocuta (spotted hyena): 144219889
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Entry
144219889 CDS
T11532
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru01522
Endocrine resistance
ccru04012
ErbB signaling pathway
ccru04062
Chemokine signaling pathway
ccru04148
Efferocytosis
ccru04151
PI3K-Akt signaling pathway
ccru04360
Axon guidance
ccru04370
VEGF signaling pathway
ccru04510
Focal adhesion
ccru04517
IgSF CAM signaling
ccru04518
Integrin signaling
ccru04670
Leukocyte transendothelial migration
ccru04810
Regulation of actin cytoskeleton
ccru04935
Growth hormone synthesis, secretion and action
ccru05100
Bacterial invasion of epithelial cells
ccru05135
Yersinia infection
ccru05146
Amoebiasis
ccru05163
Human cytomegalovirus infection
ccru05165
Human papillomavirus infection
ccru05170
Human immunodeficiency virus 1 infection
ccru05200
Pathways in cancer
ccru05202
Transcriptional misregulation in cancer
ccru05205
Proteoglycans in cancer
ccru05208
Chemical carcinogenesis - reactive oxygen species
ccru05222
Small cell lung cancer
ccru05417
Lipid and atherosclerosis
ccru05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
144219889 (PTK2)
04370 VEGF signaling pathway
144219889 (PTK2)
04151 PI3K-Akt signaling pathway
144219889 (PTK2)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
144219889 (PTK2)
04518 Integrin signaling
144219889 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
144219889 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
144219889 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
144219889 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
144219889 (PTK2)
04062 Chemokine signaling pathway
144219889 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
144219889 (PTK2)
09158 Development and regeneration
04360 Axon guidance
144219889 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
144219889 (PTK2)
05202 Transcriptional misregulation in cancer
144219889 (PTK2)
05205 Proteoglycans in cancer
144219889 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
144219889 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
144219889 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
144219889 (PTK2)
05163 Human cytomegalovirus infection
144219889 (PTK2)
05165 Human papillomavirus infection
144219889 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
144219889 (PTK2)
05100 Bacterial invasion of epithelial cells
144219889 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
144219889 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
144219889 (PTK2)
05418 Fluid shear stress and atherosclerosis
144219889 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
144219889 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccru01001
]
144219889 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
ccru01009
]
144219889 (PTK2)
Enzymes [BR:
ccru01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
144219889 (PTK2)
Protein kinases [BR:
ccru01001
]
Non-receptor tyrosine kinases
FAK family
144219889 (PTK2)
Protein phosphatases and associated proteins [BR:
ccru01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
144219889 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
ABC1
Motif
Other DBs
NCBI-GeneID:
144219889
NCBI-ProteinID:
XP_077606127
LinkDB
All DBs
Position
Unknown
AA seq
1137 aa
AA seq
DB search
MLLELAGRGALTPAGAVCMEKSGCSPFPMCWAKEYDRYIASSKIMAAAYLDPNLNHTPNS
STKTHLGTGVERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHK
VKHVACYGFRLSHLRSEEAHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGTL
QLKIAGAPEPLTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKL
ANSEKQGVRTHAVSVSGVSPRQHKVKKARRFLPLVFCSHEPSPTDEISGDETDDYAEIID
EEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKT
CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK
YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST
YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI
ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMES
RRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHVVQTNHYQVSGYPGSHGITA
MAGSIYPGQASLLDQMDSWNHRPQEISMWQPNMEDSAALDLRGIGQALPTHLMEERLIRQ
QQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPTGNQHIYQPVGKPDPAAPPKK
PPRPGAPGHLGSLASLSSPGDGYNEGVKLQPQEISPPPTANLDRSNDRVYENVTGLVKAV
IEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLPVLPASTHREIEMAQKLLNSDLG
ELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLRVLGHARPR
NT seq
3414 nt
NT seq
+upstream
nt +downstream
nt
atgttgctggaactggcgggccgaggggccctgacgccagcaggtgccgtctgtatggag
aagagcggctgtagtccatttccaatgtgttgggctaaagagtatgacagatacatagca
tcaagcaaaataatggcagctgcttaccttgacccaaacttgaatcacaccccaaattcg
agtaccaagactcatctgggtactggagtggaacgttcccctggggcaatggagcgagtg
ttgaaggtctttcactattttgagaacagcagtgagccagccacttgggccagtattatc
aggcacggagacgctaccgatgtcaggggcatcattcagaagatagtggacagtcacaaa
gtaaagcacgtggcctgctatggatttcgcctcagtcacctgcggtcagaggaggctcac
tggctccatgtggatatgggtgtctccagtgtgagggagaagtatgaacttgcacaccca
ccagaggagtggaaatatgaattgagaattcgttatttgccaaaaggatttctaaaccag
tttactgaagacaagccaactctgaatttcttctatcaacaggtgaagagcgactacatg
tcggagatagctgaccgagtggaccaggacatcgctttgaagctgggctgcctagagata
cggcgctcgtattgggagatgcgcggcaacgccctggagaagaagtccaactatgaagtg
ttagaaaaagatgttggtttgaagcgattttttcctaggagtttactggattctgtcaag
gccaaaacactaagaaaactcatccagcaaacatttagacagtttgccaacctgaacaga
gaagagagtattctgaagttctttgagatcctctccccagtgtacagatttgataaagag
tgcttcaagtgtgcccttggttcaagctggattatttcagtggaactggcgattggcccg
gaagaaggaatcagttacctcacagacaagggctgcaaccccacgcatctggccgacttc
aatcaagtgcagaccattcagtattcgaacagcgaggacaaggacaggaaaggaacgctg
cagctgaaaatcgcgggcgcccccgagcctctgacagtgacggcaccgtccctgaccatc
gctgagaacatggctgacctgatagatgggtactgccggctggtgaacggagccacacag
tccttcatcatcagaccccagaaagaaggtgaacgggctttgccatcaataccaaagctg
gccaacagcgagaagcaaggcgtgcggacacacgcggtctcggtgtcaggagtcagtccc
cgccagcataaagttaagaaagctaggcgctttctccccttggtcttctgttcccacgag
ccttctcctacggatgaaattagtggggacgaaaccgacgactatgctgagattatagac
gaagaagatacctacaccatgccctccaaaagctatggaatagatgaagccagggactat
gagattcaaagggaaagaatcgagcttggacggtgcatcggggaaggccagtttggagat
gtccaccaaggcgtctatatgagtccagagaacccggctttggcggttgcaattaaaaca
tgtaaaaactgtacttcggacagcgtgagagagaaattccttcaagaagccttaacgatg
cgtcagtttgaccacccccacatcgtgaagctgatcggcgtcatcacggagaaccccgtc
tggataatcatggagctgtgcaccctcggagagctgaggtcgtttctgcaagtgaggaag
tacagtttggatctcgcatctttgatcctatatgcctatcagcttagtacagctctggcc
tatctggagagcaaaagatttgtgcacagggacattgctgctcggaatgttctggtgtcc
tcaaatgactgcgtaaaattaggagactttggattatcccggtatatggaagacagtact
tactacaaagcttccaaaggaaagttgcctattaaatggatggctccagagtccatcaac
tttcgacgttttacctcagccagtgatgtgtggatgtttggtgtatgtatgtgggagata
ctgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatcggtcgaatt
gagaatggggagagattaccaatgcctccaaattgccctcctaccctctacagccttatg
acgaaatgctgggcctatgaccccagcaggcggccccggttcactgagctcaaagctcag
ctcagcacaatcctggaggaggagaaggctcagcaagaggagcggatgaggatggagtcc
agaagacaggtcaccgtgtcctgggactctggcgggtctgacgaagcgccacccaagccc
agcagacctggttaccctagtccaaggtcgagcgaaggattttatcccagcccacagcac
gtggtgcagaccaatcattaccaggtatctggctatcccggctcgcatgggattacagcc
atggccggcagcatctacccgggtcaggcatctcttttggaccagatggactcgtggaat
cacagaccacaggagatctcaatgtggcagcccaacatggaggactctgcagccctggac
ctgcgcgggattgggcaggcgttgccgacccacctgatggaggagcggctgatccgacag
cagcaggagatggaggaagaccagcgctggctcgagaaagaggagagattcctgaaacct
gacgtgcggctctctcgaggcagcatcgacagggaggacgggagtcttcagggcccgact
ggaaaccaacacatctatcagcctgtgggcaaaccagatcctgcagctccgccaaagaag
ccaccgcggcctggggcgcccggccacctggggagcctcgccagcctcagcagccccggg
gacggctacaacgagggcgtcaagcttcagccgcaggaaatcagccctccgcccactgcc
aacctggaccgctccaacgacagggtgtacgagaacgtgacgggcctggtgaaggccgtc
attgagatgtccagcaagatccagccggcgccgccggaggagtacgtgcccatggtgaag
gaagtcggcctggccctgcggacactactggccaccgtggacgagacccttccagtcctg
ccagccagcactcatcgagagatcgagatggcccagaagctgttgaactcggacctgggc
gagctcatcaacaagatgaagctggcacagcagtacgtcatgaccagcctgcagcaggag
tacaaaaagcagatgctgaccgccgcccacgccctggccgtggatgccaaaaacctactc
gatgtcattgaccaagccagactgagggtgctcggccacgcgaggccgcgctga
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integrated database retrieval system
