Crocuta crocuta (spotted hyena): 144224690
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Entry
144224690 CDS
T11532
Symbol
FASN
Name
(RefSeq) LOW QUALITY PROTEIN: fatty acid synthase
KO
K00665
fatty acid synthase, animal type [EC:
2.3.1.85
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru00061
Fatty acid biosynthesis
ccru01100
Metabolic pathways
ccru01212
Fatty acid metabolism
ccru04152
AMPK signaling pathway
ccru04910
Insulin signaling pathway
ccru04936
Alcoholic liver disease
Module
ccru_M00082
Fatty acid biosynthesis, initiation
ccru_M00083
Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09100 Metabolism
09103 Lipid metabolism
00061 Fatty acid biosynthesis
144224690 (FASN)
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
144224690 (FASN)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
144224690 (FASN)
09160 Human Diseases
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
144224690 (FASN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01004 Lipid biosynthesis proteins [BR:
ccru01004
]
144224690 (FASN)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ccru04147
]
144224690 (FASN)
Enzymes [BR:
ccru01000
]
2. Transferases
2.3 Acyltransferases
2.3.1 Transferring groups other than aminoacyl groups
2.3.1.85 fatty-acid synthase system
144224690 (FASN)
Lipid biosynthesis proteins [BR:
ccru01004
]
Fatty acid synthase
Animal type
144224690 (FASN)
Exosome [BR:
ccru04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
144224690 (FASN)
Exosomal proteins of breast milk
144224690 (FASN)
Exosomal proteins of colorectal cancer cells
144224690 (FASN)
Exosomal proteins of bladder cancer cells
144224690 (FASN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Acyl_transf_1
ketoacyl-synt
Thioesterase
KR
Ketoacyl-synt_C
KAsynt_C_assoc
FAS_pseudo-KR
ADH_zinc_N_2
ADH_zinc_N
PKS_DH_N
PP-binding
Methyltransf_12
adh_short
PS-DH
Methyltransf_31
Thiolase_N
ACP_SdgA_C
Methyltransf_23
Methyltransf_11
AlaDh_PNT_C
Motif
Other DBs
NCBI-GeneID:
144224690
NCBI-ProteinID:
XP_077611916
LinkDB
All DBs
Position
Unknown
AA seq
2519 aa
AA seq
DB search
MEEVVIAGMSGKLPESENLEEFWANLIGGVDMVTDDDRRWKAGLYGLPKRTGKLKDLSKF
DTSFFGVHPKQAHTMDPQLRLLLEVAYEAILDGGINPASLRGTHTGVWVGVSGSEASEAL
SRDPENLLGYSMVGCQRAMMANRLSFFFDFKGPSITLDTACSSSLLALQSAYQAIRNGEC
PAAIVGGINILLKPNTSVQFMKLGMLSPEGCCKSFDESGNGYCRSEAVVAVLLTKKSLAR
RVYATILNAGTNTDGFKEQGVTFPSGDVQEQLIRSLYEPAGLDPESLEYIEAHGTGTKVG
DPQELNSITRALCATRRDPLLIGSTKSNMGHPEPASGLAALAKVLLCLEHGLWAPNLHFH
SPNPEIPALLDGRLQVVCQPLPIRGGNVGINSFGFGGSNVHVVLQPNLRPPPAPALHAAL
PRLLLASGRTPEAVQCLLEQGQQHSQDLGLLSMLNDIAASPPTAMSCRGYTVLGGKGHGQ
EVQHVPAGERPLWFICSGMGAQWHGMGLSLMRLGSFRDSILRSDKAVRPLGLQVSELLLT
TDEATFDDNVYSFLSLTAIQIALIDLLTSVGLRPDGIIGHSLGEVACGYADGCLSQEEAI
LAAYWRGQCIKEANIPPGAMAAVGFFWEECKQRCPAGVVPACHNSEDTVTISGPQAEVAA
FVAELKQEGVFAKEVQTGGIAFHSYFMDSIAPTLLQALKKVIREPRPRSARWLSTSIPEA
QWQGSLARTFSAEYNVNNLVSPVLFQEALRHVPANAVVVEIAPHALLQAILKRGLKPSCT
ILPLMKKDQSDNLEFFLSSVGKLHLLGFSVNPNGLFPPVEFPVPRGTPLISPHIKWDHSQ
TWDVPTANDFPSGPHSSPATIYNIDTSPESPDHYLVDHCIDGRILFPATGYLCLVWKTLA
SAFGQIMEQLPVVFEDVTVHQATILPNTGTVSLEVRLLQASRSFEVSDKGSLIVSVKVYQ
WEDPDTKLFDRQDGLYRTDPTATFHLSQGDVYKELRLRSYDYGPHFQGILEANLEGTAGR
LLWNGNWVTFLDTMLQISILSVAQRTLRLPTRITSIHIDPATHLRRMYSLQDKAQAVDVV
VSSCLHSTVAGGILLSGLHAEAAPRRQQEQLVPILEKFCFTPYTEQGLLAGDPGLQEALQ
LCRGLALALQTRVAQQGLKMAVPGLDGAPAPQEPPQQGLPRLLAAACQLQLNGSLSLELG
QLLEQQRPLLQDDPLLTGLLASPALKACVDTALENTTSLKMKVVEVLAGDGHLYSRIPAL
LNTQPMLQLDYIATDRHTQALEAVQAKLQQHGIAQSQWDPSDSAPSHLGMADLLVCNCAV
ASLGDLATAIGNMRAALKEGGFLLLHVLLKGHPLGETVAFLTCPEPQRGQQSLLSQVQGX
EQDEWESLFARASLCLVAQKRSFYGSVLFLCRRPLLQDSPVFLPVEDTTFQWVDSLKNIL
DDSSLRPVWLTAVSGVTSGIVGLVNCLRKEPSGHRIRCILVSNLSSKVRTPSLDPGSSEL
QKVLQGGLVMNVYRDGAWGSFRHFPLERGLPEEQTEYAFVNVLTRGDLSSIRWVCSSLRH
PQLTSPGVQLCSVYYASLNFRDIMLAAGKLSADAIPGKWGVHDCLLGMEFSGRDASGRRV
MGLVPAEGLATSVLLSQDFLWEVPSSWTLEEAASVPVVYTTAYYSLVVRGRIQPGETVLI
HSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLSATSFANSRDTSFEQHVL
RHTAGKGVDLVLNSLAEEKLQASVRCLAQHGRFLEIGKFDLSNNHLLGMAVFLKNVTFHG
ILLDSLLDKVDARWQEVAALLKAGIRDGVVQPLKCTVFPKDRVEDAFRFMAQGKHIGKVV
VQVRQEEPEAVLREPSPTLMTAVSRTFFSAHKSYVITGGLGGFGLELAQWLVLRGARKLV
LTSRSGIRTGYQAKQVREWRRQGVQVLVSTSNASSLDGAQRLIDEATQLGPVGGVFNLAV
VLRDAVLENQTPELFQDVNKPKFSGTVNLDRVTRAACSELDYFVAFSSVSCGRGNAGQAN
YGFANSTMERVCEKRQHDGLPGLAIQWGAIGDVGLIMEGSGSNDVVIGGTLPQRITSCLE
VLDLFLNQPYPVLSSFVLAEKATSPSDSTHQQDLMKAVAHILGIRDLATVNLDSSLADLG
LDSLMGVEVRQMLEREHDLVMSMRDIRHLTLQKLQELSLKASTADELAAPTPKEDSPASQ
QAQLSLSTLLVNPEGPTLTQLNSVQSSERPLFLVHPIEGSITVFRSLASKLSIPTYGLQC
TRAAPLDSIQSLAAYYIECIRQVQPEGPYRIAGYSYGACVAFEMCSQLQAAQQSPAPTHN
SLFLFDGSHSYVLAYTQSYRAKLTPGCEAEAEAEAMFFFVQQFTNVEHSRVLEALLPLKG
LEERVAATVDLILRSHAGLDRRELSFAAHSFYHKLRAAEQYMPRATYHGNVTLLRAKTGS
VYGEGLGADYNLSQVCDGKVSVHMIEGDHRTLLEGSGLESILSIIHSSLAEPRVSVREG
NT seq
7560 nt
NT seq
+upstream
nt +downstream
nt
atggaggaggttgtgattgctggcatgtctgggaagctgcccgagtcggagaacttggag
gagttctgggccaacctcatcggtggcgtggacatggtgacagatgatgacaggaggtgg
aaggcaggactctacggcctgcccaagcggaccggcaagctgaaggacttgtccaagttc
gacacctccttcttcggggtccacccaaagcaggctcacacgatggacccccaactgcgc
ttgctactggaggtcgcctacgaggccatcctggatggaggcatcaacccagcctccctg
cgagggacacacacaggcgtctgggtgggtgtgagcggctcggaggcctcagaggctctg
agccgagaccccgagaatctcctgggctacagcatggtgggctgccagcgggctatgatg
gccaaccgtctttccttcttctttgattttaaaggacccagcatcactctggacacagcc
tgctcctccagcctgctggcgcttcagagcgcctatcaggccatccgcaacggggagtgc
ccggcggccatcgtgggcggcatcaacatcttactcaagcccaacacctccgtgcagttc
atgaagctcggcatgctgagtcccgaaggctgctgcaagtccttcgacgagtccgggaac
ggctactgccgctcagaggcggtggtggccgtcttgctgaccaagaagtccctggcccgg
cgtgtgtacgccaccatcctcaatgccggcaccaacacagacggcttcaaggagcaaggt
gtgaccttcccctctggggacgtgcaggaacagctcatccgctccttgtacgagccagcc
gggctggacccagagtctcttgagtatatcgaagcccacggcacgggcaccaaggtgggg
gacccccaggagctgaacagtatcacccgagccctgtgtgccacccgccgggaccccctg
ctgatcgggtccaccaagtcaaacatggggcaccccgagcccgcctcggggctcgcggct
ctggccaaggtgctgctgtgcctggagcacgggctctgggcccccaacctgcacttccac
agcccgaaccctgagatccccgcgcttctggacggacggctgcaggtggtgtgccagccc
ctgcccatccgcggaggcaacgtgggcatcaattcctttggcttcggtggctccaacgtg
cacgtcgtcctccagcccaacctgcggccacccccggcgcctgccctgcacgccgccctg
ccccgtctgctgctggccagcgggcgcacccctgaggccgtgcagtgcctgctcgaacag
ggccagcagcacagccaggacctaggcctcctgagcatgctcaacgacatcgcagccagc
ccccccaccgccatgtcctgccgaggctacaccgtgctgggcggcaagggccacggccag
gaggtgcagcacgtgccggctggcgagcggcccctctggttcatctgctctgggatgggc
gcgcagtggcacgggatgggcttgagcctgatgcgcctgggcagcttccgagactccatc
ctgcgctccgacaaggccgtgaggcccctgggcctgcaggtgtccgagctgctgctgacc
acggacgaggccaccttcgacgacaacgtctactccttcttgagcctcaccgccatccag
attgccctcatagacttgctgacctcggtgggtctgcggcctgacggaatcatcgggcac
tccctgggcgaggtggcctgtggctacgcagacggctgcctctcgcaggaggaggccatc
ctcgctgcctactggaggggccagtgcatcaaggaagccaacatcccgccaggggccatg
gcagccgtgggcttcttctgggaggagtgtaagcagcgctgccctgctggcgtcgtgccc
gcctgccacaactccgaggacaccgtgaccatctcaggaccgcaggcggaggtggccgcg
ttcgtggcagagctgaagcaggaaggtgtgtttgccaaggaggtgcagacgggcggcata
gccttccactcctacttcatggactccatcgcccccacgctgctgcaggcgctcaagaag
gtgatccgggagccgcggccccgctcggctcgctggctcagcacgtccatccctgaggct
cagtggcagggcagcctggcccgcacgttctcggcggagtacaatgtcaacaacctggtg
agccccgtgctgttccaggaggcgctgcggcacgtgcccgccaacgccgtggtggtggag
atcgccccccacgccctgctgcaggccattctcaagagaggcctcaagcccagctgcacc
atccttcccctgatgaagaaggaccagagtgacaacctggagttcttcctcagcagcgtg
ggcaagttgcacctgttaggcttcagcgtcaaccccaacggcctgtttccacccgtggag
tttccagttccccgggggacccctctcatctcccctcacatcaagtgggaccatagtcag
acctgggacgtgcccaccgccaatgacttccccagcggccctcacagctcgcctgccacc
atctacaacatcgacaccagccccgagtcccctgaccactacctggtggaccactgcatc
gacggccgcatcctcttcccggccaccggctacctgtgcctggtctggaagactctggca
agtgcctttggccaaatcatggagcagctgcccgtggtgtttgaggacgtgacggtgcat
caggctaccatcctgcccaataccgggaccgtgtccctggaagtgcggcttctacaggct
tcccgaagcttcgaggtgtctgacaagggcagcctgatagtgagcgtgaaggtttaccag
tgggaggaccccgacaccaagctcttcgacaggcaggacggcctgtaccgcacggacccc
acggctacgttccacctgagccagggggacgtgtacaaagagctgcgtctgcgcagctat
gactacggccctcatttccagggcatccttgaggccaaccttgaaggcaccgcgggccgg
ctgctgtggaatggcaattgggtgacgttcctggacaccatgctgcagatctccatcctg
agcgtggcccagcgcaccctacgcctgcccacacgcatcacctccatccacatcgacccc
gccacccacctgcgcaggatgtactcgctgcaggacaaggcccaagcggttgacgtggtg
gtgagcagctgtctgcacagcacggtggccggcggcatcctcctgtcgggcctccacgcc
gaggcggccccgaggcggcagcaggagcagctcgtacccatcctggagaagttctgcttc
acgccgtacacagagcaggggctcctcgctggagacccaggcctgcaggaggcgctacag
ctgtgcagagggctggcactggcactgcagactagggtggcccagcaggggctgaagatg
gcggtacctgggctggacggggccccagccccccaggagccaccgcagcaaggcctgccc
cgcctgctggcggctgcctgccagctgcagctcaatgggagcctctcactggagctgggc
cagctgctggagcagcagcgccctctgctgcaggacgaccccctgctcaccggcctcctc
gcctccccggcgctcaaggcctgcgtggacaccgccctggagaacacgaccagcctcaag
atgaaggttgtggaggtgctggctggcgacggccacctatattcccgcatcccagcgctg
cttaacacccagcccatgctgcagctggactacatagccacggaccgccacactcaggcc
ctggaggctgtccaggccaagctgcagcagcacggcatagcccagagccagtgggacccc
tcggactccgcccccagccacctgggcatggctgatctccttgtgtgtaactgtgccgtg
gccagcctcggtgatctggccacggccatcggcaacatgcgggccgctctcaaggagggt
ggcttcctacttctgcacgtcctgctcaaaggacaccccctcggagagacggtcgccttc
ctcacgtgccctgagccacaacgaggccagcagagcctcctcagccaggtgcaggggcnt
gagcaggacgagtgggagagtctgtttgccagggcatccctgtgcctagtggcccagaag
aggtccttctacggttccgtgctcttcctgtgccgccggccgctcctgcaggacagccct
gtcttcctgcctgtggaggacaccaccttccagtgggtagactccctgaagaacattctg
gacgactcctccctccggcccgtgtggctgaccgctgtcagtggggtcacctcaggcatc
gtgggcttggtgaactgcctccgcaaggagcccagcgggcaccggatccggtgcatcctg
gtgtccaacctcagcagcaaggttcgcacccccagtttggaccctggctcctcagagctg
cagaaggtgctgcaggggggccttgtgatgaacgtctaccgagacggggcctgggggtcc
ttccgccatttcccactggagcgtggcctgccggaggagcaaaccgagtacgccttcgtg
aacgtcctcacccggggggacctctcctccatccgctgggtctgctcgtctctgcggcac
ccccagctcaccagccctggcgtccagctctgttctgtctactatgcctcccttaacttc
cgagatatcatgctggccgcaggcaagctctccgctgatgccatcccagggaaatggggc
gtccacgactgtttgctgggcatggagttctctggccgagacgccagcggcaggcgtgtc
atggggctggtgcccgctgaaggcctggctacctctgtcctgctctctcaggacttcctt
tgggaggtgccctccagctggaccctagaggaggcagcttcagtgcctgtggtctacacc
accgcctactactcgctggtggtgcgggggcgcatacagcctggggagacggtgctcatc
cactcgggttcaggcggcgtgggccaggccgccatcgccatcgcactcagtctgggctgc
cgcgtcttcacgactgtggggtcggccgagaagcgggcgtacctccaggccaggttcccc
cagctcagtgccaccagctttgccaactcccgggacacgtcttttgaacagcacgtgctg
cggcacacggcagggaagggtgtggacctggtcttgaattctctggcggaagagaagctg
caggccagcgtgcggtgcctggcccagcacggccggttcctggaaatcggcaaattcgac
ctttccaacaaccacctgctgggcatggccgttttcctgaagaacgtgaccttccacggg
atcctgctggactcgctcctggacaaggtcgacgccaggtggcaggaggtggcggcgctg
ctgaaagcaggcatccgggacggcgtggtgcagcccctcaagtgcaccgtcttccccaag
gaccgggtggaggacgcattccgcttcatggcccaagggaagcatatcgggaaggtggtc
gtccaggtgcgccaggaggagccggaggcggtgctgcgggagccgagtcccaccctgatg
accgccgtgtccaggaccttcttctcggcccacaagagctacgtcatcaccgggggcctg
ggcggcttcggcctggagctggcccagtggcttgtgctgcgaggggcccggaagctcgtg
ctgacctctcgctccggaatccgcacaggctaccaggccaagcaggtccgggagtggagg
cgtcagggcgtgcaggtcctggtgtccaccagcaacgccagttcgctggatggggcccag
agactaatcgatgaggccacacagctgggccccgtgggaggcgtcttcaacctggccgtg
gtcctgagagatgccgtgctggagaaccaaaccccggagctcttccaggacgtcaacaag
cccaagttcagcggcactgtgaaccttgacagggtgacccgagctgcgtgctccgagctg
gactacttcgtggctttctcctctgtgagctgcgggcgtggcaatgctggccaggccaac
tacggcttcgccaactccaccatggagcgtgtgtgtgagaagcgccagcatgatggcctc
ccgggcctcgccattcagtggggcgccatcggcgacgtaggcctcatcatggagggttca
ggttccaacgacgtggtcatcggtggaacgctgccccagcggatcacctcctgcctggag
gtgctggacctctttctgaaccagccctaccccgtcttgagcagcttcgtgctggccgag
aaggccaccagccccagtgacagcactcaccagcaggatctgatgaaggccgtggcccac
atcctgggcatccgagacttggccaccgtcaacctggacagctctctggcggacttgggc
ctggactcgctcatgggcgtggaggtgcgccagatgctggagcgggagcacgacctggtg
atgtccatgagggacatccggcatctgacgctgcagaagctacaggaactctccttgaag
gccagcacagctgacgagctggcagcccccacgcccaaggaagacagccctgccagccag
caggcccagctgagcctgagcaccctgctggtgaatcctgagggcccgaccttgacgcag
ctcaactcggtgcagagctcggagcgccccctgttcctggtgcatcccatcgaaggctcc
atcactgtgttccgcagcctggcgtccaagctcagcatccccacctacggcttacagtgc
actcgagctgcgcctctggacagcatccagagtctggccgcctactacatcgagtgcatc
aggcaggtgcagccggaggggccctaccgcatcgctggctattcctacggggcctgcgtg
gccttcgagatgtgttcgcagctacaggccgcacagcagagccctgcccccacacataac
agtctcttcctgttcgatggctcacactcctacgtgctggcctacacgcagagttaccgc
gcaaagctgacccctggctgtgaggccgaggccgaggccgaggccatgttcttctttgtg
cagcagttcaccaacgtggagcacagcagggtgctggaggcgctgctgccccttaagggc
ctggaggagcgcgtggcagccaccgtggacctgatcctgcgcagccacgcaggcctggac
cgccgcgagctgagcttcgccgctcattccttctaccacaagctgcgagcagccgagcag
tacatgccgcgggccacctaccacggcaacgtgacgctgctgcgcgccaagactggcagc
gtgtacggtgagggcctgggtgccgactacaacctgtcccaggtgtgcgacggcaaggtg
tccgtgcacatgattgagggcgaccaccgcacgctgctagagggcagcggcctggagtcc
atcctcagcatcatccacagctccctggctgagccacgtgtcagcgtccgggagggctag
DBGET
integrated database retrieval system
