Crocuta crocuta (spotted hyena): 144225957 Help Entry 144225957         CDS       T11532                                  Symbol HK3 Name (RefSeq) hexokinase-3   KO K00844   hexokinase [EC:2.7.1.1] Organism ccru  Crocuta crocuta (spotted hyena) Pathway ccru00010   Glycolysis / Gluconeogenesis ccru00051   Fructose and mannose metabolism ccru00052   Galactose metabolism ccru00500   Starch and sucrose metabolism ccru00520   Amino sugar and nucleotide sugar metabolism ccru00524   Neomycin, kanamycin and gentamicin biosynthesis ccru01100   Metabolic pathways ccru01200   Carbon metabolism ccru01250   Biosynthesis of nucleotide sugars ccru04066   HIF-1 signaling pathway ccru04910   Insulin signaling pathway ccru04930   Type II diabetes mellitus ccru04973   Carbohydrate digestion and absorption ccru05230   Central carbon metabolism in cancer Module ccru_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ccru_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc ccru_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:ccru00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     144225957 (HK3)    00051 Fructose and mannose metabolism     144225957 (HK3)    00052 Galactose metabolism     144225957 (HK3)    00500 Starch and sucrose metabolism     144225957 (HK3)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     144225957 (HK3)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     144225957 (HK3)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     144225957 (HK3)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     144225957 (HK3)   09154 Digestive system    04973 Carbohydrate digestion and absorption     144225957 (HK3)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     144225957 (HK3)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     144225957 (HK3)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ccru04131]     144225957 (HK3) Enzymes [BR:ccru01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      144225957 (HK3) Membrane trafficking [BR:ccru04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     144225957 (HK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  144225957 NCBI-ProteinID:  XP_077613392 LinkDB All DBs Position Unknown AA seq 924 aa AA seqDB search MDSVGPVGLQQGEGAPSCSQEGLPCPSDSSELVLECLQQFKVTRTQLQQIQAGLLGSMEQ ALAGQVSPAPAVRMLPTYVGSTPHGTEQGDFLVLELGATGASLRVLWVTLTGTEGHRMEP RSQEFVIPPEVMLGPGQQLFDFAAHCLSEFLDALPVSTQDLQLGFNFSFPCHQTGLDRST LISWTKGFRCSGVEGHDVVQLLRDAIKRQGAYNIDVVAVVNDTVGTMMGCEPGIGPCEVG LVVDTGTNACYMEEARHVAVLDEDRGRVCVSVEWGSFGDDEVLGPVLTTFDRALDRESLN PGAQRFEKMIGGLYLGELVRLVLAHLAQRGVLFGGCTSPALMSRGSILLEHVAEMEDPLA GAARVHAILQDLGLSVGASDAELVQYVCAAVFTRAARLCAAALAAVLSRLQHSQEQQMLQ IAVATGGRVFERYPSFLSILRETVMLLAPECDVSFIPSVDGGGRGVAMVTAVAARLAAHR RLLEETLAPFRLNHEQLAAVQAQMQEAMANGLRGEASSLRMLPTYVRATPDGSERGDFLA LDLGGTNFRVLLVRVTAGGVQITNQVYSIPACVAQGSGQQLFDHIVDCIVDFQQKQGLSG QSLPLGFTFSFPCRQLGLDQGILLNWTKGFNASDCEGQDVVCLLREAIGRRQAVKLNVVA IVNDTVGTMMSCGYEDPRCEIGLIVGTGTNACYMEELRNIAGVAGDSGQMCINMEWGAFG DDGSLGLLRTSFDANVDQASINPGKQSFEKMISGMYLGEIVRHILLHLTSLGVLFRGQQT QCLQTRDIFKTKFLSEIESDSLALRQVRAILEDLGLPLTSDDALMVLEVCQAVSQRAAQL CGAGVAAVVEKIRENRGLDELTISVGVDGTLYKLHPHFSGLVAATVRELAPRCVVTFLQS EDGSGKGAALVTAVACRLAQMDHV NT seq 2775 nt NT seq  +upstreamnt  +downstreamnt atggactccgttgggccagtagggttgcagcagggggaaggagctcctagctgctcccag gagggcttgccttgcccctcagacagctctgagctggtgctggaatgcctacagcaattc aaggtgacacggacacagctgcagcagatccaagctggcctcctgggctctatggagcag gccctagcggggcaggtcagccctgcccctgctgtccggatgctgcccacatacgtgggg tccaccccacatggcactgaacaaggagattttttggtgctggagctgggggccacaggg gcctcactgcgtgttctgtgggtgaccctgacgggtactgagggacacaggatggaaccc cggagccaggagtttgtgatccccccagaggtgatgctgggtcctggtcagcagctcttt gactttgctgcccactgcctgtctgagttcctggatgcactccctgtgagcactcaggat ctgcagcttgggttcaacttctccttcccttgtcaccagacgggactggacaggagcacc ctcatttcctggaccaaaggttttaggtgcagtggtgtggaaggccatgacgttgtccag ttactgcgagatgccatcaagagacagggggcctacaacatcgatgtggttgccgtggtg aatgacacagtgggcaccatgatgggctgcgagccagggattgggccatgtgaggtcggg cttgttgtagacactggcaccaatgcatgctacatggaggaggcaaggcacgtggcggtg ctggatgaggaccggggccgtgtctgcgtcagcgttgagtggggctccttcggcgatgat gaagttctgggaccagtgctgaccacctttgaccgtgccttggaccgagagtccctgaat cctggtgctcagaggtttgagaagatgattgggggcttatacctgggtgagctggtgagg cttgtgttggctcacttggcccagcgaggagtcctctttggcggctgcacctcccctgcc ctgatgagccgaggcagcatcctcctagagcatgtggctgagatggaggaccccctggct ggggcagcccgtgtgcatgctatcctgcaggacttgggcctgagcgtgggggcctcggat gctgagcttgtgcagtatgtgtgcgcagccgtgtttacacgggctgcccggctctgtgct gctgccctggctgccgttctctcccgcctccaacacagccaggagcagcagatgcttcag atcgctgtggccaccggaggccgagtgtttgagcgatatcccagtttcctcagcatcctg cgggagactgtgatgctcctggcccctgaatgtgatgtctccttcattccctctgtggat gggggcggccggggcgtggcaatggtgactgctgtggctgcccgcctggctgctcaccgg cgcctgctggaagagacccttgcaccattccggttgaaccatgaacagctggcagcagtg caggcacagatgcaggaagccatggccaacgggctccgaggggaggcctcatccctccgc atgctgcccacttatgtgcgggccactcctgatggcagtgagcgcggggacttcctggcc ctggaccttgggggcaccaacttccgggtcctcctggtgcgtgtgaccgcaggaggtgtg cagatcaccaaccaggtctactccatcccagcgtgtgtggctcagggctctggacagcag ctcttcgaccacatcgtggactgcattgtggacttccagcagaagcaaggcctgagtggg cagagcctccccctgggtttcaccttctccttcccatgcaggcagcttggcctggaccag ggcatccttctaaattggacaaagggtttcaatgcatcagattgtgagggccaagatgtt gtatgtctgctgcgggaagccatcgggcggagacaggcagtgaagctgaatgtggttgcc attgtcaatgacacggtggggaccatgatgtcctgtggctatgaggatccccgttgtgag atcggcctcattgttggaactggcaccaatgcctgctacatggaagagcttcggaatata gcaggtgtggctggggattcaggtcaaatgtgcatcaatatggagtggggagcctttggc gatgatggctctctgggcttgctcagaaccagctttgatgcaaatgtggaccaggcatcc atcaaccctggcaagcagagttttgagaagatgatcagtggcatgtacctgggggagatc gtccgtcatattctcttgcatttgaccagccttggagttctcttccggggccagcagacc cagtgccttcagaccagggacatcttcaagaccaaatttctctctgagattgaaagtgac agcctggctctgaggcaggtccgagccatcctggaggatctggggctgcccctgacctca gatgatgccctgatggttctggaggtgtgccaggctgtgtctcagcgggctgcccagctc tgtggggcgggtgtggctgccgtggtggagaagatccgtgagaaccggggcctagatgag ctgaccatatccgtgggggtggatgggaccctctacaagctgcacccccacttctccggc ctggtggcagccacagtcagggagctagccccccgctgtgtggtcaccttcctgcagtcg gaagacgggtctggcaaaggtgcagccctggtcactgcggttgcctgccgccttgcccag atggaccatgtttga

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