Crocuta crocuta (spotted hyena): 144233386 Help Entry 144233386         CDS       T11532                                  Symbol HK2 Name (RefSeq) hexokinase-2   KO K00844   hexokinase [EC:2.7.1.1] Organism ccru  Crocuta crocuta (spotted hyena) Pathway ccru00010   Glycolysis / Gluconeogenesis ccru00051   Fructose and mannose metabolism ccru00052   Galactose metabolism ccru00500   Starch and sucrose metabolism ccru00520   Amino sugar and nucleotide sugar metabolism ccru00524   Neomycin, kanamycin and gentamicin biosynthesis ccru01100   Metabolic pathways ccru01200   Carbon metabolism ccru01250   Biosynthesis of nucleotide sugars ccru04066   HIF-1 signaling pathway ccru04910   Insulin signaling pathway ccru04930   Type II diabetes mellitus ccru04973   Carbohydrate digestion and absorption ccru05230   Central carbon metabolism in cancer Module ccru_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ccru_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc ccru_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:ccru00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     144233386 (HK2)    00051 Fructose and mannose metabolism     144233386 (HK2)    00052 Galactose metabolism     144233386 (HK2)    00500 Starch and sucrose metabolism     144233386 (HK2)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     144233386 (HK2)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     144233386 (HK2)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     144233386 (HK2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     144233386 (HK2)   09154 Digestive system    04973 Carbohydrate digestion and absorption     144233386 (HK2)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     144233386 (HK2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     144233386 (HK2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ccru04131]     144233386 (HK2) Enzymes [BR:ccru01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      144233386 (HK2) Membrane trafficking [BR:ccru04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     144233386 (HK2) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  144233386 NCBI-ProteinID:  XP_077622347 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDENLLEISQRFRKEMEKGLGATTHPTAS VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLRVRVTDNGLQKVEMENQIYAIPEDLMR GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCVQTKLDESFLVSWTKGFKSSGV EGKDVVTLIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDQNCEIGLIVGTGSNACYME EMRHIDMVEGDEGRMCINMEWGAFGDDGALDDFRTEFDQEIDMGSLNPGKQLFEKMISGM YMGELVRLILVKMAKEELLFGGKVSPGLLATGQFETKDVSDIEGEKDGIRKAREVLVRLG IDPTQEDCVATHRVCQIVSTRSASLCAATLAAVLRRIKENKGEERLRSTIGVDGSVYKKH PHFAKRLHKTVRRLVPDCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQNTLESLKLS REQLLEVKRRMKVEMERGLSKETHAIAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV LLVRVRNGKRRGVEMHNKIYSIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG TMMTCGYEDPHCEIGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD FRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG IFETKFLSQIESDCLALLQVRAILHHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA VVDKIRENRGLDTLKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLESEDGSGKG AALITAVACRIREAGQR NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgatcgcctcacatctgctcgcctacttcttcacggagctcaaccatgaccaagtgcag aaggtcgaccagtatctctaccacatgcgtctttctgatgagaaccttctggagatctct cagcggttccgcaaggagatggagaaagggcttggagccaccacccaccccactgcttca gtgaaaatgctgcccacctttgtgaggtctactccagatgggacagaacatggggagttc ctggctctggatcttggagggaccaacttccgtgtgcttcgtgtaagagtaacagacaat gggctccagaaggtcgagatggagaaccagatctatgccatccctgaagatctcatgcga ggcagcggcacccagctgtttgaccacattgcagaatgcctggctaacttcatggataag ctacaaatcaaagacaagaagctccccttgggttttactttctcgttcccctgtgtccaa acgaagctggatgagagtttcctggtctcctggaccaaggggttcaagtccagtggtgtg gaaggcaaagatgtggttactctgatccggaaggccatccagaggagaggggactttgat attgatattgtggctgtggtgaatgatacagttgggaccatgatgacctgtggttatgat gaccagaattgcgagattggtctcattgtgggtacgggcagcaatgcctgctacatggaa gagatgcgccacattgacatggtggagggcgacgaggggcgaatgtgtatcaacatggag tggggggcctttggggatgacggcgcactcgatgacttccgcactgaatttgatcaggag atcgacatgggttccctgaatcccgggaagcaactatttgagaagatgatcagtgggatg tacatgggcgaactggtgagactcatcctggtgaagatggccaaggaggagctgcttttt ggggggaaagtcagcccaggtctccttgctactggccagttcgagaccaaagacgtttca gatattgaaggggagaaggatggcatccggaaggcccgcgaggtgctagtgcggctgggc atagacccgacgcaggaggactgtgtggccactcaccgggtgtgccagattgtgtccaca cgctcagccagcctgtgtgcagccaccctggcagctgtgctacggcgcatcaaggagaac aagggcgaggagcggctgcgctccaccattggggttgatggctctgtctacaagaagcac cctcattttgccaagcgtcttcataagacagtgcgacgcctggtgcctgactgtgacgtc cgcttcctgcgttccgaggatggcagtggcaagggggcagccatggtgacggcagtggcc taccggctggctgaccaacaccgagcccgccagaataccctggagtctctgaagctgagc cgcgagcagctgctggaggtcaagaggaggatgaaggtagaaatggagcgaggtctgagc aaggagacccacgccattgcccctgtcaagatgctgcccacctacgtgtgtgccacccct gatggcacagagaaaggtgacttcctggccttggaccttgggggtaccaatttccgagtc ctgctggtgcgcgtgaggaatgggaagaggcgtggagtggagatgcacaacaagatctac tctatcccgcaggaggtcatgcatggcacaggggacgagctctttgaccacattgtccaa tgcattgccgacttccttgagtacatgggcatgaagggcgtgtccctgcctctgggcttc accttctccttcccctgccagcagaacagcctggatgagagcatcctcctcaagtggact aaaggcttcaaggcatcgggctgcgagggagaggatgtggtcaccctgctgaaggaagcc atccaccggcgagaggaatttgacctggacgtggtcgccgtggtgaatgacacagtcggg acgatgatgacctgtggctatgaagatcctcactgtgaaatcggcctcatcgttggcacg ggcagcaacgcctgctacatggaggagatgcggaacgtggagctggtggagggggaggag ggccggatgtgtgtcaacatggaatggggggctttcggggacaacgggtgcctcgacgac ttccgcacggaatttgatgtggctgtggatgagctttccctcaaccctggcaaacagagg tttgagaaaatgatcagtggcatgtacttgggtgagattgtccgtaacatcctcatcgat tttaccaagcgtgggctgctcttccgtggccgcatctcagagcggctcaagacaagagga atctttgaaaccaagttcctgtctcagattgagagtgactgcctagccctgctgcaggtc cgcgccatcctgcaccacctggggctcgagagcacctgtgacgacagcatcatcgtcaaa gaggtgtgcacggtggtggcacggcgggcagcccagctctgtggtgccggcatggccgcc gtggtggacaaaatacgagaaaaccgtgggctggacaccctcaaagtgacagtgggcgtg gatgggaccctttacaagctacatcctcactttgccaaagtcatgcatgagacggtgaaa gacctggctccgaaatgtgatgtgtccttcctggagtcagaagatggcagcgggaagggg gcagctctcatcactgctgtggcctgccgcatccgtgaggctggacagcgatag

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