Crocuta crocuta (spotted hyena): 144233677
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Entry
144233677 CDS
T11532
Symbol
EIF2AK3
Name
(RefSeq) LOW QUALITY PROTEIN: eukaryotic translation initiation factor 2-alpha kinase 3
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru04137
Mitophagy - animal
ccru04140
Autophagy - animal
ccru04141
Protein processing in endoplasmic reticulum
ccru04210
Apoptosis
ccru04932
Non-alcoholic fatty liver disease
ccru05010
Alzheimer disease
ccru05012
Parkinson disease
ccru05014
Amyotrophic lateral sclerosis
ccru05020
Prion disease
ccru05022
Pathways of neurodegeneration - multiple diseases
ccru05160
Hepatitis C
ccru05162
Measles
ccru05168
Herpes simplex virus 1 infection
ccru05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
144233677 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
144233677 (EIF2AK3)
04137 Mitophagy - animal
144233677 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
144233677 (EIF2AK3)
09160 Human Diseases
09172 Infectious disease: viral
05160 Hepatitis C
144233677 (EIF2AK3)
05162 Measles
144233677 (EIF2AK3)
05168 Herpes simplex virus 1 infection
144233677 (EIF2AK3)
09164 Neurodegenerative disease
05010 Alzheimer disease
144233677 (EIF2AK3)
05012 Parkinson disease
144233677 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
144233677 (EIF2AK3)
05020 Prion disease
144233677 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
144233677 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
144233677 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
144233677 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ccru01001
]
144233677 (EIF2AK3)
Enzymes [BR:
ccru01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
144233677 (EIF2AK3)
Protein kinases [BR:
ccru01001
]
Serine/threonine kinases: Other
PEK family [OT]
144233677 (EIF2AK3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PQQ_2
Kinase-like
Kdo
ABC1
DUF7670
Motif
Other DBs
NCBI-GeneID:
144233677
NCBI-ProteinID:
XP_077622818
LinkDB
All DBs
Position
Unknown
AA seq
1086 aa
AA seq
DB search
MERATRPGPLVRALLLQLLLGLAAGTVAAARATDLPTPKVEAAFGLGAAXPAAAVEQETR
EPEPDDEAELQPRGRSLVIISTLDGRIAALDPENHGKKQWDLDVGSGSLVSSSLSKPEVF
GNKMIIPSLDGDLFQWDRDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAY
SGKVRYICSALGCRQWDNEEMEQEDILLLQRSQKTVRAVGPRSGNEKWNFSVGHFELRYI
PDVETRAGFIESTLKPSGHKEGSKIISDVEEQEASMMDTVIKVSVADWKVMAFNKKGGHL
EWEYQFCTPIASAWLVKDGKVIPISLFDDTSYASNDDVLEDEEDIVEAARGATENSVYLG
MYRGQLYLQSSVRISEKFPTSPKALESVNNEYAIVPLPTIKWKPLIHSPSRTPVLVGSDE
FDKCLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERSKRSTQITVRFLDNPNYNKN
IRKKDPVLLLHWWKEIVGTILFCIVATTFIVRRLFHPHPQRQRKESETQCQTESKYDSVS
GEAKESTWNDIKNSGYVSRYLSDFEXXXXXXXXGFGVVFEARNKVDDCNYAIKRIRLPNR
ELAREKVMREVKALAKLDHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDESTDWPLSSPSP
VDGPSVKICRMDPFSTKEHIEIIAPSSQRRSFSVGISCGRTSSSESQFSPLELSGTDHGD
TSESVDAAYNLQDSCLTDCDVEDGTMDGNGEGHSFELCPSQASLYERSRERTSSSIVFED
SGCDNASRKEEHKTNRLHIGNHCANKLTTFKPSRSKSSSEPTFSISPPRPTTLSLDLTKN
TAEKLQPSSPKVYLYIQMQLCRKENLKDWMNSRCSIEERERGVCLHIFLQIAEAVEFLHS
KGLMHRDLKPSNIFFTVDDVVKVGDFGLVTAMDQDEEEQMVLTPMPACARHTGQVGTKLY
MSPEQIHGSNYSHKVDIFSLGLILFELLYPFGTQMERVRILTDVRNLKFPPLFTQKYPHE
YVMVQDMLSPSPMERPEATNIIENAVFEDLEFPGKTVLRQRSRSMSSSGTKHSRQCSSSW
SPLPSN
NT seq
3258 nt
NT seq
+upstream
nt +downstream
nt
atggagcgcgccacccgccctgggccgctcgtgcgggctctgctgctgcagctgctgctg
gggctcgcggctggcacggtggccgcagctcgcgccaccgacctccccacgccgaaggtg
gaggcggcgttcggcctgggcgccggncccgcggccgcagtcgagcaggagacgcgggag
ccggaacccgacgacgaggccgagctacagccgcgaggcagatcattagtgattatcagc
actttggatgggcgaatagctgccttggatcctgagaaccatggtaaaaaacagtgggat
ttggacgtgggatctggttccttggtctcatccagcctcagcaaaccagaggtatttggg
aataagatgatcattccttccctggatggagacctttttcagtgggaccgggaccgtgag
agcatggaaactgttccttttacagttgaatcacttcttgaatcttcgtataaatttgga
gacgatgttgttttggttggaggaaagtctctgactacatatggactcagtgcatatagt
ggaaaggtgaggtacatctgctcagctttgggttgtcgccagtgggacaatgaggagatg
gaacaggaagacatcttacttctgcagcgctcccagaaaaccgttagagctgtcggaccg
cgcagtggcaatgagaagtggaatttcagtgttggccactttgaacttcggtatattcca
gacgtggaaactagagccggatttattgaaagcaccttaaagcccagtgggcacaaagaa
gggtctaaaattatttcagatgtggaagaacaagaagcctccatgatggacacagtgata
aaggtgtcagttgctgactggaaggttatggcctttaacaagaagggaggacatctggaa
tgggaataccagttttgtactcccattgcatctgcctggctggttaaggacggaaaagtc
attcccattagtctttttgatgatacaagttatgcatctaatgatgatgttttagaagat
gaagaagacattgtagaagctgctcgaggagccacagaaaacagcgtttacttggggatg
tacagaggtcagctgtatctgcagtcatctgtcagaatttcagaaaagtttcctacaagt
cctaaggccttggaatctgtcaacaatgagtatgcaattgttccgttgccaacaatcaaa
tggaagcccttaatccattctccttccaggactcctgtcttggtagggtctgatgaattt
gacaaatgtcttagtaatgataagttttctcatgaagagtacagtaatggcgccctttcc
atcttgcaatacccatatgataatggttattatctaccatactacaagagagagaggagc
aaacggagcacacagatcacagtccgatttctcgataacccaaattacaacaagaacatt
cgcaaaaaggatcctgttctcctcttacactggtggaaagaaatagtcggaactattctg
ttttgtattgtagcaacaacttttattgtgcgtagacttttccatcctcaccctcaaaga
caaaggaaggaatcggaaactcagtgtcaaactgaaagcaaatatgattctgtaagtgga
gaagccaaggaaagtacctggaatgacataaaaaattctggatatgtatcacgatatcta
tctgattttgagnnnnnnnnnnnnnnnnnnnnnnnngggtttggagttgtctttgaagcc
cgaaataaagttgatgactgcaattacgctatcaagagaatccgtctccccaacagggaa
ttggctcgggaaaaggtaatgcgagaagttaaagccttagccaagcttgaccatccagga
attgtgaggtatttcaatgcttggttggaagcaccacctgagaagtggcaagaaaaaatg
gatgaaatatggctgaaagatgaaagcacagactggccactcagctctcctagtccagtg
gatggaccgtccgttaaaatatgcagaatggatcctttctctacaaaggaacatattgag
atcatagccccttcttcacaaaggaggtccttttcagtagggatttcctgtggccggaca
agctcatctgagagccagttctctccactggaattatcgggaacggaccatggagatacc
agtgagtccgtggatgcagcctacaacctccaggacagttgccttacagactgcgatgtg
gaagacggtaccatggacggcaacggcgaggggcactcctttgaactttgtccttctcag
gcttctctttatgaaaggtcaagggagagaacgtcctcttcgatagtgtttgaagactct
ggctgtgataacgcatccaggaaagaagagcacaaaactaaccgactgcatattggcaac
cattgtgctaataaactaactactttcaagccttccaggagcaaatcctcctctgagcct
actttctctatttctcctccaagaccgaccactttaagtttagatctcactaaaaacact
gcagaaaaactccagcccagttcgccgaaggtatacctttacattcagatgcagctctgc
cgaaaggaaaacctcaaagactggatgaacagccgatgcagcatagaggagagagagagg
ggcgtgtgtctgcacatcttcctgcagatcgcagaggccgtagagtttctgcacagtaaa
gggctcatgcacagggacctcaagccatccaacatattctttacagtggacgatgtggtc
aaggttggagactttggattagtgactgcaatggaccaggatgaggaagagcagatggtc
ctgaccccaatgccagcgtgtgccagacacacaggacaagtggggaccaaactgtatatg
agcccagagcagattcacggaagcaactactcccataaagtggacatcttctctttaggc
ctcattctgtttgaactgctgtacccattcggcactcagatggagagagtcaggatcttg
actgatgtaagaaatctcaaatttccaccactgtttactcagaaatatcctcatgagtat
gtgatggttcaagacatgctgtctccatctcccatggaacggcctgaagctactaacatt
attgaaaatgctgtgtttgaagacttggaatttccaggaaaaactgtactcagacagagg
tctcggtccatgagttcgtcgggaacgaaacattcaagacagtgcagcagctcctggagc
cctttgccaagcaattaa
DBGET
integrated database retrieval system
