KEGG   Crocuta crocuta (spotted hyena): 144237367
Entry
144237367         CDS       T11532                                 
Symbol
TRAF2
Name
(RefSeq) TNF receptor-associated factor 2
  KO
K03173  TNF receptor-associated factor 2 [EC:2.3.2.27]
Organism
ccru  Crocuta crocuta (spotted hyena)
Pathway
ccru04010  MAPK signaling pathway
ccru04064  NF-kappa B signaling pathway
ccru04071  Sphingolipid signaling pathway
ccru04137  Mitophagy - animal
ccru04141  Protein processing in endoplasmic reticulum
ccru04210  Apoptosis
ccru04217  Necroptosis
ccru04380  Osteoclast differentiation
ccru04621  NOD-like receptor signaling pathway
ccru04622  RIG-I-like receptor signaling pathway
ccru04657  IL-17 signaling pathway
ccru04668  TNF signaling pathway
ccru04920  Adipocytokine signaling pathway
ccru04932  Non-alcoholic fatty liver disease
ccru05010  Alzheimer disease
ccru05014  Amyotrophic lateral sclerosis
ccru05016  Huntington disease
ccru05017  Spinocerebellar ataxia
ccru05022  Pathways of neurodegeneration - multiple diseases
ccru05132  Salmonella infection
ccru05135  Yersinia infection
ccru05160  Hepatitis C
ccru05163  Human cytomegalovirus infection
ccru05167  Kaposi sarcoma-associated herpesvirus infection
ccru05168  Herpes simplex virus 1 infection
ccru05169  Epstein-Barr virus infection
ccru05170  Human immunodeficiency virus 1 infection
ccru05200  Pathways in cancer
ccru05203  Viral carcinogenesis
ccru05222  Small cell lung cancer
ccru05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ccru00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    144237367 (TRAF2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    144237367 (TRAF2)
   04064 NF-kappa B signaling pathway
    144237367 (TRAF2)
   04668 TNF signaling pathway
    144237367 (TRAF2)
   04071 Sphingolipid signaling pathway
    144237367 (TRAF2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    144237367 (TRAF2)
  09143 Cell growth and death
   04210 Apoptosis
    144237367 (TRAF2)
   04217 Necroptosis
    144237367 (TRAF2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    144237367 (TRAF2)
   04622 RIG-I-like receptor signaling pathway
    144237367 (TRAF2)
   04657 IL-17 signaling pathway
    144237367 (TRAF2)
  09152 Endocrine system
   04920 Adipocytokine signaling pathway
    144237367 (TRAF2)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    144237367 (TRAF2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    144237367 (TRAF2)
   05203 Viral carcinogenesis
    144237367 (TRAF2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    144237367 (TRAF2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    144237367 (TRAF2)
   05160 Hepatitis C
    144237367 (TRAF2)
   05168 Herpes simplex virus 1 infection
    144237367 (TRAF2)
   05163 Human cytomegalovirus infection
    144237367 (TRAF2)
   05167 Kaposi sarcoma-associated herpesvirus infection
    144237367 (TRAF2)
   05169 Epstein-Barr virus infection
    144237367 (TRAF2)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    144237367 (TRAF2)
   05135 Yersinia infection
    144237367 (TRAF2)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    144237367 (TRAF2)
   05014 Amyotrophic lateral sclerosis
    144237367 (TRAF2)
   05016 Huntington disease
    144237367 (TRAF2)
   05017 Spinocerebellar ataxia
    144237367 (TRAF2)
   05022 Pathways of neurodegeneration - multiple diseases
    144237367 (TRAF2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    144237367 (TRAF2)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    144237367 (TRAF2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:ccru03019]
    144237367 (TRAF2)
   04121 Ubiquitin system [BR:ccru04121]
    144237367 (TRAF2)
Enzymes [BR:ccru01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     144237367 (TRAF2)
Messenger RNA biogenesis [BR:ccru03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Stress granule specific factors
     144237367 (TRAF2)
Ubiquitin system [BR:ccru04121]
 Ubiquitin ligases (E3)
  Single Ring-finger type E3
   TRAF proteins
    144237367 (TRAF2)
SSDB
Motif
Pfam: TRAF-mep_MATH MATH_2 TRAF_BIRC3_bd zf-TRAF TRAF2_zf zf-C3HC4 TRAF3_RING zf-C3HC4_2 zf-C3HC4_4 zf-RING_5 SLX5_C zf-RING_UBOX zf-RING_6 zf-C3HC4_5 zf-RING_2 MATH
Other DBs
NCBI-GeneID: 144237367
NCBI-ProteinID: XP_077627142
LinkDB
Position
Unknown
AA seq 521 aa
MAAASVTPPGSLDLLQPGFSKTLLGTKPEDKYLCSACRNVLRRPFQAQCGHRYCSSCLTS
ILSSGPQNCAACVHEGIYEEGISILESGSAFPDNAARREVESLPAVCPSDGCTWKGTLKE
YESCHEGHCPFMLTECPACRGLVRLGEKERHSEQECPERSLSCRHCRAPCCWAGLQAHHE
VCPKFPLTCDGCGKKKISREKFQDHVRACGKCRVPCRFHTVGCPEMVESEKQQQHEAQWL
REHLALLLGGLLEAKHLSAADGRLRGPGGGCEAGTPHPEAELSKAAELRQRCEALERKTA
TFENIVCVLNREVERVAMTAEACGRQHRLDQDRIEALSNKVQQLERSIGLKDLAMAELEQ
KVHEMEASTFDGVFIWKISDFARKRQEAVAGRTPAIFSPAFYTSRYGYKMCLRIYLNGDG
TGRGTHLSLFFVVMKGPNDALLRWPFNQKVTLMLLDQNNREHVIDAFRPDVTSSSFQRPV
SDMNIASGCPLFCPVSKMEAKNSYVRDDAIFIKAIVDLTGL
NT seq 1566 nt   +upstreamnt  +downstreamnt
atggctgcggccagcgtgacccctcctggctccctcgacctgctgcagcccggcttctcc
aagaccctgctggggaccaagccggaggacaagtacctgtgctcggcctgcaggaacgtc
ctgcgcaggcctttccaggcgcagtgtggccaccgctactgctcctcctgtctgactagc
atcctcagctccgggccccagaactgtgccgcctgcgttcacgagggcatatatgaagaa
ggcatttctattttggaaagtggttcggctttcccggacaacgccgcacgcagggaggtg
gagagcctgccggctgtctgtcccagcgacggctgcacctggaaggggacccttaaagag
tatgagagctgccacgaaggacactgccccttcatgctgaccgagtgcccggcgtgcaga
ggcctggtccgcctcggggagaaggagcggcactcggagcaggagtgtccggagaggagc
ctcagctgccggcactgccgggcgccctgctgctgggccggcctgcaggcacaccacgaa
gtctgccccaagttccccctgacatgtgacggctgtggcaagaagaagatctcccgggag
aaattccaggaccacgtgcgggcgtgtggcaaatgccgagtcccatgcaggttccacacc
gtcggctgccccgagatggtggagagtgagaagcagcagcagcacgaggcgcagtggctg
cgggagcacctggccctgctgctgggtggcctcctggaggccaagcacctgtcagcagct
gacggccgcctccggggcccaggcgggggctgcgaagctggcacaccgcaccccgaggcg
gagctctccaaggctgcggagctccggcagcggtgcgaggccctggagaggaagacggcc
accttcgagaacatcgtctgcgtcctgaaccgggaggtggagagggtggccatgaccgcc
gaggcctgtggccggcagcaccgcctggaccaggacaggatcgaggccctgagtaacaag
gtgcagcagctggagaggagcatcggcctgaaggacctggcgatggccgagctggagcag
aaggtccacgagatggaggcgtccaccttcgacggcgtgttcatctggaagatctccgac
ttcgccaggaagcgccaagaagctgtggccggccgtacgccggccatcttctccccagcc
ttctacacgagcaggtacggctacaagatgtgtctgcgcatctacctgaacggggacggc
accgggcgtgggacacacctgtctctcttctttgtggtgatgaagggccccaacgatgcc
ctcctgcggtggcccttcaaccaaaaggtgaccttaatgctgcttgaccagaacaaccga
gagcacgtgatcgacgcctttagacccgacgtgacctcgtcctctttccagaggccggtc
agtgacatgaacatcgcgagtggctgccccctcttctgccctgtttccaagatggaggct
aagaattcctacgtgcgcgatgacgccatcttcatcaaggccattgtggacctgacgggg
ctctag

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