Crocuta crocuta (spotted hyena): 144239726
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Entry
144239726 CDS
T11532
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X1
KO
K13375
transforming growth factor beta-1
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru04010
MAPK signaling pathway
ccru04060
Cytokine-cytokine receptor interaction
ccru04068
FoxO signaling pathway
ccru04110
Cell cycle
ccru04148
Efferocytosis
ccru04218
Cellular senescence
ccru04350
TGF-beta signaling pathway
ccru04380
Osteoclast differentiation
ccru04390
Hippo signaling pathway
ccru04518
Integrin signaling
ccru04659
Th17 cell differentiation
ccru04672
Intestinal immune network for IgA production
ccru04926
Relaxin signaling pathway
ccru04932
Non-alcoholic fatty liver disease
ccru04933
AGE-RAGE signaling pathway in diabetic complications
ccru05140
Leishmaniasis
ccru05142
Chagas disease
ccru05144
Malaria
ccru05145
Toxoplasmosis
ccru05146
Amoebiasis
ccru05152
Tuberculosis
ccru05161
Hepatitis B
ccru05166
Human T-cell leukemia virus 1 infection
ccru05200
Pathways in cancer
ccru05205
Proteoglycans in cancer
ccru05210
Colorectal cancer
ccru05211
Renal cell carcinoma
ccru05212
Pancreatic cancer
ccru05220
Chronic myeloid leukemia
ccru05225
Hepatocellular carcinoma
ccru05226
Gastric cancer
ccru05321
Inflammatory bowel disease
ccru05323
Rheumatoid arthritis
ccru05410
Hypertrophic cardiomyopathy
ccru05414
Dilated cardiomyopathy
ccru05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
144239726 (TGFB1)
04350 TGF-beta signaling pathway
144239726 (TGFB1)
04390 Hippo signaling pathway
144239726 (TGFB1)
04068 FoxO signaling pathway
144239726 (TGFB1)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
144239726 (TGFB1)
04518 Integrin signaling
144239726 (TGFB1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
144239726 (TGFB1)
09143 Cell growth and death
04110 Cell cycle
144239726 (TGFB1)
04218 Cellular senescence
144239726 (TGFB1)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
144239726 (TGFB1)
04672 Intestinal immune network for IgA production
144239726 (TGFB1)
09152 Endocrine system
04926 Relaxin signaling pathway
144239726 (TGFB1)
09158 Development and regeneration
04380 Osteoclast differentiation
144239726 (TGFB1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
144239726 (TGFB1)
05205 Proteoglycans in cancer
144239726 (TGFB1)
09162 Cancer: specific types
05210 Colorectal cancer
144239726 (TGFB1)
05212 Pancreatic cancer
144239726 (TGFB1)
05225 Hepatocellular carcinoma
144239726 (TGFB1)
05226 Gastric cancer
144239726 (TGFB1)
05220 Chronic myeloid leukemia
144239726 (TGFB1)
05211 Renal cell carcinoma
144239726 (TGFB1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
144239726 (TGFB1)
05161 Hepatitis B
144239726 (TGFB1)
09171 Infectious disease: bacterial
05152 Tuberculosis
144239726 (TGFB1)
09174 Infectious disease: parasitic
05146 Amoebiasis
144239726 (TGFB1)
05144 Malaria
144239726 (TGFB1)
05145 Toxoplasmosis
144239726 (TGFB1)
05140 Leishmaniasis
144239726 (TGFB1)
05142 Chagas disease
144239726 (TGFB1)
09163 Immune disease
05323 Rheumatoid arthritis
144239726 (TGFB1)
05321 Inflammatory bowel disease
144239726 (TGFB1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
144239726 (TGFB1)
05414 Dilated cardiomyopathy
144239726 (TGFB1)
05415 Diabetic cardiomyopathy
144239726 (TGFB1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
144239726 (TGFB1)
04933 AGE-RAGE signaling pathway in diabetic complications
144239726 (TGFB1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03110 Chaperones and folding catalysts [BR:
ccru03110
]
144239726 (TGFB1)
09183 Protein families: signaling and cellular processes
04052 Cytokines and neuropeptides [BR:
ccru04052
]
144239726 (TGFB1)
00536 Glycosaminoglycan binding proteins [BR:
ccru00536
]
144239726 (TGFB1)
Chaperones and folding catalysts [BR:
ccru03110
]
Intramolecular chaperones
Others
144239726 (TGFB1)
Cytokines and neuropeptides [BR:
ccru04052
]
Cytokines
Transforming growth factors (RSTK binding)
144239726 (TGFB1)
Glycosaminoglycan binding proteins [BR:
ccru00536
]
Heparan sulfate / Heparin
Growth factors/receptors
144239726 (TGFB1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
TGFb_propeptide
TGF_beta
Motif
Other DBs
NCBI-GeneID:
144239726
NCBI-ProteinID:
XP_077630016
LinkDB
All DBs
Position
Unknown
AA seq
391 aa
AA seq
DB search
MPPSGLRLLPLLLPLLWLLVLTPGRPVAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRGAGESAEPEPEPEADYYAKEVTRVLMVENTNKI
YDKVQRTPHSIYMLFNTSELREAVPEPVLLSRAELRLLRLKLKAEQHVELYQKYSNDSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLSHGGEVEGFRLSAHCSCDSKDNTLQVDINAGF
SSSRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLY
IDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQ
ALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgccgccctccgggctgcggctgctgccgctgctgctgccgctgctgtggctactagtg
ctgacgcctggccggccggtcgccggactgtccacctgcaagaccatcgacatggaactg
gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgcc
agccccccgagccagggggaggtgccgcccggcccgctgcccgaggccgtgctggccctt
tacaacagcacccgcgaccggggggccggggagagcgccgagccggagcccgagccggag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaacaccaacaaaatc
tatgataaagtccagcgtaccccacacagcatatatatgctctttaacacatcggagctc
cgagaagcagtgcctgagcccgtcttgctctcccgggcagagttgcgtctgctgaggctc
aagttaaaagcggagcagcacgtggagctgtatcagaaatacagcaatgattcctggcgc
tacctcagcaaccggctgctggcgcccagcgactcgccggaatggctgtcctttgatgtc
actggagtggtgcggcagtggctgagccatggaggggaagtagagggctttcgcctcagt
gcccactgttcctgcgacagcaaagataacacactgcaagtggacatcaacgcagggttc
agttccagccgccgaggtgacctggccaccatccatggcatgaaccggccctttctgctc
ctcatggccaccccgctggagagggcccagcacctgcacagctcgcgccaccgccgggcc
ctggacaccaactactgcttcagctccacggagaagaactgctgcgtgaggcagctctat
attgacttccgcaaggatctgggctggaaatggatccacgagcccaagggctaccacgcc
aacttctgcctggggccctgtccctacatctggagcctggacacgcagtacagcaaggtc
ctggccctgtacaaccagcacaacccgggcgcgtcggcggctccctgctgcgtgccgcag
gccctggagccactgccgatcgtatactacgtgggccgcaagcccaaggtggagcagctt
tccaacatgatcgtgcgctcctgcaagtgcagctga
DBGET
integrated database retrieval system