KEGG   Crocuta crocuta (spotted hyena): 144239726
Entry
144239726         CDS       T11532                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X1
  KO
K13375  transforming growth factor beta-1
Organism
ccru  Crocuta crocuta (spotted hyena)
Pathway
ccru04010  MAPK signaling pathway
ccru04060  Cytokine-cytokine receptor interaction
ccru04068  FoxO signaling pathway
ccru04110  Cell cycle
ccru04148  Efferocytosis
ccru04218  Cellular senescence
ccru04350  TGF-beta signaling pathway
ccru04380  Osteoclast differentiation
ccru04390  Hippo signaling pathway
ccru04518  Integrin signaling
ccru04659  Th17 cell differentiation
ccru04672  Intestinal immune network for IgA production
ccru04926  Relaxin signaling pathway
ccru04932  Non-alcoholic fatty liver disease
ccru04933  AGE-RAGE signaling pathway in diabetic complications
ccru05140  Leishmaniasis
ccru05142  Chagas disease
ccru05144  Malaria
ccru05145  Toxoplasmosis
ccru05146  Amoebiasis
ccru05152  Tuberculosis
ccru05161  Hepatitis B
ccru05166  Human T-cell leukemia virus 1 infection
ccru05200  Pathways in cancer
ccru05205  Proteoglycans in cancer
ccru05210  Colorectal cancer
ccru05211  Renal cell carcinoma
ccru05212  Pancreatic cancer
ccru05220  Chronic myeloid leukemia
ccru05225  Hepatocellular carcinoma
ccru05226  Gastric cancer
ccru05321  Inflammatory bowel disease
ccru05323  Rheumatoid arthritis
ccru05410  Hypertrophic cardiomyopathy
ccru05414  Dilated cardiomyopathy
ccru05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ccru00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    144239726 (TGFB1)
   04350 TGF-beta signaling pathway
    144239726 (TGFB1)
   04390 Hippo signaling pathway
    144239726 (TGFB1)
   04068 FoxO signaling pathway
    144239726 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    144239726 (TGFB1)
   04518 Integrin signaling
    144239726 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    144239726 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    144239726 (TGFB1)
   04218 Cellular senescence
    144239726 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    144239726 (TGFB1)
   04672 Intestinal immune network for IgA production
    144239726 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    144239726 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    144239726 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    144239726 (TGFB1)
   05205 Proteoglycans in cancer
    144239726 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    144239726 (TGFB1)
   05212 Pancreatic cancer
    144239726 (TGFB1)
   05225 Hepatocellular carcinoma
    144239726 (TGFB1)
   05226 Gastric cancer
    144239726 (TGFB1)
   05220 Chronic myeloid leukemia
    144239726 (TGFB1)
   05211 Renal cell carcinoma
    144239726 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    144239726 (TGFB1)
   05161 Hepatitis B
    144239726 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    144239726 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    144239726 (TGFB1)
   05144 Malaria
    144239726 (TGFB1)
   05145 Toxoplasmosis
    144239726 (TGFB1)
   05140 Leishmaniasis
    144239726 (TGFB1)
   05142 Chagas disease
    144239726 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    144239726 (TGFB1)
   05321 Inflammatory bowel disease
    144239726 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    144239726 (TGFB1)
   05414 Dilated cardiomyopathy
    144239726 (TGFB1)
   05415 Diabetic cardiomyopathy
    144239726 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    144239726 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    144239726 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:ccru03110]
    144239726 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ccru04052]
    144239726 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:ccru00536]
    144239726 (TGFB1)
Chaperones and folding catalysts [BR:ccru03110]
 Intramolecular chaperones
  Others
   144239726 (TGFB1)
Cytokines and neuropeptides [BR:ccru04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   144239726 (TGFB1)
Glycosaminoglycan binding proteins [BR:ccru00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   144239726 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 144239726
NCBI-ProteinID: XP_077630016
LinkDB
Position
Unknown
AA seq 391 aa
MPPSGLRLLPLLLPLLWLLVLTPGRPVAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRGAGESAEPEPEPEADYYAKEVTRVLMVENTNKI
YDKVQRTPHSIYMLFNTSELREAVPEPVLLSRAELRLLRLKLKAEQHVELYQKYSNDSWR
YLSNRLLAPSDSPEWLSFDVTGVVRQWLSHGGEVEGFRLSAHCSCDSKDNTLQVDINAGF
SSSRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLY
IDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQ
ALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgccgccctccgggctgcggctgctgccgctgctgctgccgctgctgtggctactagtg
ctgacgcctggccggccggtcgccggactgtccacctgcaagaccatcgacatggaactg
gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgcc
agccccccgagccagggggaggtgccgcccggcccgctgcccgaggccgtgctggccctt
tacaacagcacccgcgaccggggggccggggagagcgccgagccggagcccgagccggag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaacaccaacaaaatc
tatgataaagtccagcgtaccccacacagcatatatatgctctttaacacatcggagctc
cgagaagcagtgcctgagcccgtcttgctctcccgggcagagttgcgtctgctgaggctc
aagttaaaagcggagcagcacgtggagctgtatcagaaatacagcaatgattcctggcgc
tacctcagcaaccggctgctggcgcccagcgactcgccggaatggctgtcctttgatgtc
actggagtggtgcggcagtggctgagccatggaggggaagtagagggctttcgcctcagt
gcccactgttcctgcgacagcaaagataacacactgcaagtggacatcaacgcagggttc
agttccagccgccgaggtgacctggccaccatccatggcatgaaccggccctttctgctc
ctcatggccaccccgctggagagggcccagcacctgcacagctcgcgccaccgccgggcc
ctggacaccaactactgcttcagctccacggagaagaactgctgcgtgaggcagctctat
attgacttccgcaaggatctgggctggaaatggatccacgagcccaagggctaccacgcc
aacttctgcctggggccctgtccctacatctggagcctggacacgcagtacagcaaggtc
ctggccctgtacaaccagcacaacccgggcgcgtcggcggctccctgctgcgtgccgcag
gccctggagccactgccgatcgtatactacgtgggccgcaagcccaaggtggagcagctt
tccaacatgatcgtgcgctcctgcaagtgcagctga

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