Crocuta crocuta (spotted hyena): 144242944
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Entry
144242944 CDS
T11532
Symbol
EZH2
Name
(RefSeq) histone-lysine N-methyltransferase EZH2 isoform X1
KO
K11430
[histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:
2.1.1.356
]
Organism
ccru Crocuta crocuta (spotted hyena)
Pathway
ccru00310
Lysine degradation
ccru01100
Metabolic pathways
ccru03083
Polycomb repressive complex
ccru05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ccru00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
144242944 (EZH2)
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
144242944 (EZH2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
144242944 (EZH2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ccru03036
]
144242944 (EZH2)
Enzymes [BR:
ccru01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase
144242944 (EZH2)
Chromosome and associated proteins [BR:
ccru03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
144242944 (EZH2)
Polycomb repressive complex (PRC) and associated proteins
PRC2.1
144242944 (EZH2)
PRC2.2
144242944 (EZH2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ezh2_MCSS
PRC2_HTH_1
SET
preSET_CXC
Motif
Other DBs
NCBI-GeneID:
144242944
NCBI-ProteinID:
XP_077634100
LinkDB
All DBs
Position
Unknown
AA seq
747 aa
AA seq
DB search
METAKDTACPHPDFCELIARDQGGHSPALPSTIFHNTVFTWNQPSAKSLSLVVSSYNYYF
WLDFPLQLPVVRPHSRLLYQLVDCSVTSDLDFPTQIIPLKTLNAVASVPIMYSWSPLQQN
FMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFVELVNALG
QYNDDDDDDDGDDPDEREEKQKDLEENRDDKESRPPRKFPSDKIFEAISSMFPDKGTAEE
LKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKYDCFLHPF
HATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPPKRPGGRRRGRLP
NNSSRPSTPTINVLESKDTDSDREAGAETGGENNDKEEEEKKDETSSSSEANSRCQTPIK
MKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVYEFRVKESSIIAP
VPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPRQPCDSSCPCVIA
QNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLTCGAADHWDSKNV
SCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYD
KYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTG
EELFFDYRYSQADALKYVGIEREMEIP
NT seq
2244 nt
NT seq
+upstream
nt +downstream
nt
atggaaacagcgaaggatacagcctgtccacatcctgacttctgtgagctcattgcgcgg
gaccagggaggccattcacctgctcttccctctacgattttccataacacagtttttact
tggaaccagccttctgccaagagtctcagtttggttgtgtcctcctacaactactatttt
tggcttgacttccctctccagctcccagtggtccggccacacagtcgcctattgtaccag
ctggttgattgttcagtgaccagtgacttggattttccaacacaaatcatcccattaaag
actctgaatgcagtcgcgtcagtgcccataatgtattcttggtctcccctacagcagaat
tttatggtggaagatgaaacggtcttacacaacattccttacatgggggacgaagtccta
gaccaggacgggacgttcatcgaggagctgataaaaaattatgatggaaaagtacatggg
gatagagaatgtggttttataaatgatgaaatttttgtggagttggtgaatgctctgggt
cagtacaatgatgatgatgatgatgatgatggagatgatcctgatgaaagagaagaaaaa
cagaaagatctggaggagaacagagatgataaagaaagccgcccgcctcggaaatttcct
tctgataaaatttttgaagccatttcctcaatgtttccagataagggcacagcagaagaa
ctcaaggaaaagtataaggagctgacggagcagcagctcccgggcgctcttcctcctgag
tgcactccgaacatcgacgggccgaacgccaagtccgtgcagagggagcagagcctgcac
tccttccacacactcttctgccggcgctgctttaagtacgactgcttcctgcaccctttt
cacgcaacacccaacacttacaagcggaagaacacagaaacggctctggacaacaagcca
tgtggaccacagtgttaccagcacctggaaggagcgaaggagtttgctgccgctctcacg
gccgagcggataaagacgccgccgaagcgacccggaggccgcaggagggggaggctgccc
aacaacagcagcaggcccagcacccccaccatcaatgtgctggagtccaaggacacagac
agcgaccgggaggcgggggccgagacgggcggggagaacaacgacaaggaggaggaggag
aagaaggacgagacgtccagctcctccgaagcgaattctcggtgtcagacgccaataaag
atgaagccaaacattgagcctcctgagaacgtggagtggagtggcgccgaggcctccatg
ttccgggtcctcatcggcacgtattatgacaatttctgtgccattgccaggctcatcggg
accaaaacttgtagacaggtgtatgagttccgtgtcaaagaatcgagcattatagctcca
gtgccggccgaggatgttgatacccctccaaggaagaagaagaggaaacaccggttgtgg
gctgcccactgcagaaagatacagctgaaaaaggatggctcctctaatcatgtttacaac
tatcagccctgtgaccacccacggcagccttgtgacagttcgtgcccttgtgtgatagca
cagaatttctgtgagaagttttgtcagtgcagttcagagtgtcagaaccgcttccccggc
tgccgctgcaaagcccagtgcaacaccaagcagtgcccgtgctacctggccgtgcgcgag
tgcgaccccgacctctgcctcacgtgtggcgcggccgaccactgggacagcaagaacgtg
tcctgcaagaactgcagcatccagcggggctccaagaagcacttgctgctggcgccctcc
gacgtggcgggctgggggattttcatcaaagatcctgtgcagaagaatgagttcatctcg
gagtactgtggggagattatttctcaagacgaagccgacagaagagggaaagtgtatgac
aagtacatgtgcagcttcctgttcaacttgaacaatgattttgtggtggatgcaacccgc
aagggtaacaaaattcgttttgcaaatcattcagtaaatccaaactgctatgcaaaagtc
atgatggttaacggcgatcacaggatagggatttttgctaagagagccatccagaccggt
gaagagctgttttttgattacagatacagccaggcggatgccctcaagtacgtgggcatc
gagagagaaatggaaatcccttga
DBGET
integrated database retrieval system
