Crocuta crocuta (spotted hyena): 144243456 Help Entry 144243456         CDS       T11532                                  Name (RefSeq) hexokinase HKDC1 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism ccru  Crocuta crocuta (spotted hyena) Pathway ccru00010   Glycolysis / Gluconeogenesis ccru00051   Fructose and mannose metabolism ccru00052   Galactose metabolism ccru00500   Starch and sucrose metabolism ccru00520   Amino sugar and nucleotide sugar metabolism ccru00524   Neomycin, kanamycin and gentamicin biosynthesis ccru01100   Metabolic pathways ccru01200   Carbon metabolism ccru01250   Biosynthesis of nucleotide sugars ccru04066   HIF-1 signaling pathway ccru04910   Insulin signaling pathway ccru04930   Type II diabetes mellitus ccru04973   Carbohydrate digestion and absorption ccru05230   Central carbon metabolism in cancer Module ccru_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ccru_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc ccru_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:ccru00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     144243456    00051 Fructose and mannose metabolism     144243456    00052 Galactose metabolism     144243456    00500 Starch and sucrose metabolism     144243456   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     144243456   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     144243456  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     144243456  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     144243456   09154 Digestive system    04973 Carbohydrate digestion and absorption     144243456  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     144243456   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     144243456  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ccru04131]     144243456 Enzymes [BR:ccru01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      144243456 Membrane trafficking [BR:ccru04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     144243456 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 Motif Other DBs NCBI-GeneID:  144243456 NCBI-ProteinID:  XP_077634643 LinkDB All DBs Position Unknown AA seq 917 aa AA seqDB search MFAVHLMAFYFTKLKEDQIKKVDRFLYHMRLSDDTLLDIMARFQAEMQRGLGKDTNPTAS VKMLPTFVRAIPDGSEHGEFLSLDLGGSKFRVLKVQVSEEGKRNVQMESQFYPTPNEIIR GNGSELFDYVADCLADFMKTKGLKHKKLPLGLTFSFPCRQTKLEEGILLSWTKKFKARGV QDTDIVKCLTKAIQKHKDIDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL YLGELVRIILLKMAKVGLLFGGKKSSALHTKGKIETRHVAAMEKYKEGLANTREILTDLG LEPSEADCLAVQQVCTIVSFRSANLCAAALAAILTRLRENKKLVRLRTTVGVDGTLYKIH PQYPKRLHKVVRRLVPNCDVRFLLSESGSTKGAAMVTAVASRVQAQRRQIDKVLALFRLT QEQLKGVQSKMRTELEYGLKKDTHLLATVKMLPTYVCGMPDGTEKGKFLALDLGGTNFRV LLVKIRSGRKSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGAQLPLGFT FSFPCRQTSIDKGILIEWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT MMTCGYEDPNCEIGLIAGTGSNMCYMEEMKNIELVEGDEGKMCINTEWGGFGDNGCIDDI RTQYDRKVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAV VEKRREDQGLEYLKVTVGVDGTLYKLHPHFSRILQETVKELAPRCDVTLMLSEDGSGKGA ALITAVAKRLQQAQKEK NT seq 2754 nt NT seq  +upstreamnt  +downstreamnt atgtttgcggtacacttgatggcattttacttcaccaagctgaaggaggatcagatcaag aaggtggacaggttcctgtatcacatgcggctctccgatgacacccttttggacatcatg gctcggttccaggccgaaatgcagaggggcctagggaaggacaccaaccccacagcctcc gtgaagatgcttcccacctttgtcagggccattccagatggctcagaacatggggagttt ctttccctggatcttggagggtccaagtttcgagtcttgaaggtgcaggtctctgaggag gggaaaagaaatgtccagatggagagtcagttctacccaacacccaatgaaattatccga ggaaacggctcagagctgtttgactatgtggctgactgtctggcagatttcatgaagacc aaagggttgaagcataagaaattgccccttggcctaaccttttcttttccctgcaggcag actaaactggaagagggcatcctgctttcatggaccaagaagtttaaggcacggggagtt caagacacagatatagtgaagtgtctgaccaaagctatacaaaaacacaaggacatagat gtggacatcctggccttggtcaacgacaccgtgggcaccatgatgacatgtgcctatgac gatccctactgtgaagttggtgtcatcatcggcaccggcaccaacgcgtgctacatggag gacatgagcaacattgacctggtggaaggcgacgagggcaggatgtgcatcaacacggag tggggggcctttggggacgacggggctctggaagacatccgcaccgagttcgaccgggag ctggacctcggctctctcaaccctggcaagcagctgtttgagaagatgatcagcggccta tacctgggtgaacttgtcaggatcatcttgctgaagatggccaaggtgggcctcctgttt ggcggcaagaaatcctctgctcttcacactaagggcaagattgaaacacggcacgtggct gccatggagaagtataaagaaggcctggccaatacaagagagatcctgacagatctgggc ctggagccttcggaggccgactgcctcgcggtccagcaagtctgcaccatcgtctccttc cgctcagccaacctctgcgccgcggccctggcggccatcctgacacgcctccgggagaac aagaagctggtgcggctccggaccacggtgggcgtggacggcacgctctacaagatacac ccacaatacccaaaacgcctgcacaaggtggtgaggagactggtcccgaactgtgacgtc cgcttcctcttgtcagagagtggaagcaccaagggggctgccatggtgacagcggtggcc tcccgtgtgcaggcccaacggaggcagatcgacaaggtgctggctttgttccggctgact caagagcaactcaagggtgtgcagagcaagatgcgaactgagcttgagtacgggttgaaa aaggacacccacttgctggccacggtcaagatgctgcccacctatgtttgcgggatgccg gatggtacagagaaaggcaagttccttgccctggatctggggggaaccaacttccgggtc ctcctggtaaagatcagaagtggacggaagtcagtgcgaatgtacaacaagatctttgcc atccccttggagatcatgcagggcaccggagaggagctgtttgaccacattgtgcaatgc atcgctgacttcctggactacatgggcctcaagggagcacagctgcccttgggcttcaca ttctcatttccttgcaggcagacgagtattgacaagggaatactcattgagtggaccaaa ggcttcaaggccactgactgtgaaggggaagacgtagtggacatgctcagggaagccatc aagaggagaaatgagtttgacctggacatagttgcggttgtgaatgacacagtggggacc atgatgacctgtggatatgaagatcctaactgtgagattggcctgattgcagggacaggc agcaacatgtgctacatggaggagatgaagaacatcgaactggtggaaggagatgaaggg aagatgtgcattaacaccgagtggggagggtttggagataatggctgcatagacgacatc cggacgcagtatgacaggaaggtggacgaggggtccttgaaccctggcaaacagagatac gagaaaatgaccagcgggatgtacctgggggagattgtgcggcagatcctgattgacctc accaagcagggactccttttccgtgggcagatttcagagcgtctccggaccaggggcatc tttgaaaccaagtttctgtcccagattgaaagcgatcggctggccctcctccaggtccgg aggatcctgcagcagcttggcctggacagcacgtgtgaggacagcatcgtggtgaaggag gtgtgcggggctgtgtcccggcgggcagcccagctctgtggcgctggcctggcagccgtc gtggagaagaggagggaagatcaggggcttgagtacctgaaggtcaccgtgggtgtggat ggcaccctgtacaagctgcacccgcatttttctcggatattgcaggaaaccgtgaaagag ttagctcctcgatgcgacgtgacgctcatgctgtcagaagatgggagtggaaagggagcc gctctgatcaccgctgtggccaagaggttacagcaggcacagaaggagaaatag

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