Crocuta crocuta (spotted hyena): 144243557 Help Entry 144243557         CDS       T11532                                  Symbol HK1 Name (RefSeq) hexokinase-1 isoform X1   KO K00844   hexokinase [EC:2.7.1.1] Organism ccru  Crocuta crocuta (spotted hyena) Pathway ccru00010   Glycolysis / Gluconeogenesis ccru00051   Fructose and mannose metabolism ccru00052   Galactose metabolism ccru00500   Starch and sucrose metabolism ccru00520   Amino sugar and nucleotide sugar metabolism ccru00524   Neomycin, kanamycin and gentamicin biosynthesis ccru01100   Metabolic pathways ccru01200   Carbon metabolism ccru01250   Biosynthesis of nucleotide sugars ccru04066   HIF-1 signaling pathway ccru04910   Insulin signaling pathway ccru04930   Type II diabetes mellitus ccru04973   Carbohydrate digestion and absorption ccru05230   Central carbon metabolism in cancer Module ccru_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate ccru_M00549   UDP-Glc biosynthesis, Glc => UDP-Glc ccru_M01015   GDP-Man biosynthesis, Man => GDP-Man Brite KEGG Orthology (KO) [BR:ccru00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     144243557 (HK1)    00051 Fructose and mannose metabolism     144243557 (HK1)    00052 Galactose metabolism     144243557 (HK1)    00500 Starch and sucrose metabolism     144243557 (HK1)   09107 Glycan biosynthesis and metabolism    00520 Amino sugar and nucleotide sugar metabolism     144243557 (HK1)   09110 Biosynthesis of other secondary metabolites    00524 Neomycin, kanamycin and gentamicin biosynthesis     144243557 (HK1)  09130 Environmental Information Processing   09132 Signal transduction    04066 HIF-1 signaling pathway     144243557 (HK1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     144243557 (HK1)   09154 Digestive system    04973 Carbohydrate digestion and absorption     144243557 (HK1)  09160 Human Diseases   09161 Cancer: overview    05230 Central carbon metabolism in cancer     144243557 (HK1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     144243557 (HK1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ccru04131]     144243557 (HK1) Enzymes [BR:ccru01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.1  hexokinase      144243557 (HK1) Membrane trafficking [BR:ccru04131]  Autophagy   Mitophagy    Other mitophagy associated  proteins     144243557 (HK1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Hexokinase_2 Hexokinase_1 UvrD-helicase Motif Other DBs NCBI-GeneID:  144243557 NCBI-ProteinID:  XP_077634820 LinkDB All DBs Position Unknown AA seq 921 aa AA seqDB search MGQSCQRGCREASERAIEPPLTEMKIDKYLYAMRLSDETLLDIMTRFKKEMKNGLSRDYN PTATVKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEQNQNVHMESEIYDTPE NIVHGSGSQLFDHVAECLGDFMEKKKIKDKKLPVGFTFSFPCRQSKIDEAVLITWTKKFK ASGVEGMDVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQQCEVGLIIGTGTNA CYMEELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKM VSGMYLGELVRLILVKMAKEGLLFEGRITPELLTRGKLKTSDVSAIEKNKEGLHNAKDIL TRLGVEPSDDDCISVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSL YKTHPQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAH FRLTKDMLLEVKKRMRTEMDMGLRKQTHEKAVVKMLPSFVRSTPDGTEHGDFLALDLGGT NFRVLLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRM PLGFTFSFPCKQTSLDAGILITWTKGFKATDCVGNDVATLLREAIKRREEFDLDVVAVVN DTVGTMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMLEGDQGRMCINMEWGAFGDNG CLDDIRTIYDRLVDEYSLNAGKQRFEKMISGMYLGEIVRNILIDFTKKGFLFRGQISEPL KTRGIFQTKYLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGA GMAAVVDKIRENRGLDHLSVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDG SGKGAALITAVGVRLREEASS NT seq 2766 nt NT seq  +upstreamnt  +downstreamnt atggggcagagctgccagcgaggatgtagagaagcatctgaaagggcaatcgagccccca cttactgaaatgaagattgacaagtatctctatgccatgcggctctccgatgaaactctg ttggatatcatgactcggttcaagaaggagatgaagaatggcctctcccgggattataat ccaacagccacagtcaagatgttgccaacgtttgtaaggtctattcctgatggttcagaa aagggagatttcattgccctggatcttggcgggtcttcctttcgaattctgagggtgcaa gtgaatcatgagcaaaaccagaatgttcacatggagtccgagatttatgacaccccggag aacatcgtgcacggcagtggaagccagcttttcgaccatgttgccgagtgcctgggggac ttcatggagaagaaaaaaatcaaggacaagaaactacctgtggggttcacgttttctttc ccctgccggcagtccaaaatagacgaggctgtcctgatcacctggaccaagaaatttaaa gcaagtggagtggagggaatggatgtggtgaaactgcttaacaaagccatcaaaaagcgc ggggactatgatgccaacattgtggctgtggtgaacgacacggtggggaccatgatgacc tgtggctatgacgaccagcagtgtgaagttggccttatcattggcactggcaccaatgca tgctacatggaggaactgaggcacattgacctggtggaaggcgacgagggcaggatgtgc atcaacacagagtggggggcctttggggatgatgggtcccttgaagacatccgcaccgag ttcgaccgggagatagaccgaggctctctcaaccctgggaagcagctgtttgagaagatg gtcagtggcatgtacttgggggagctcgttcgactgatcctggtcaagatggccaaggaa ggcctcttatttgaagggcggatcaccccggagctgctcaccagagggaagctcaaaacc agtgatgtgtcagccattgaaaagaacaaggaaggcctccacaatgccaaagacatcctg acccgcctgggagtggagccgtctgatgacgactgtatttcagtccagcacgtgtgtacc atcgtctcgtttcgctctgccaacctggtggcggcaacgctgggcgccatcttgaaccgc cttcgagataacaagggcacgcccaggctgcggaccacggttggcgtcgacgggtctctt tacaagacgcacccacagtattcacgacgtttccacaagactctgaggcgcttggtgccc gactctgatgtgcgcttcctcctctcggagagtggcagcggcaagggggccgccatggtc accgcggtggcctaccgcctggccgagcagcaccggcagatagaggagaccttggcccac ttccgcctcaccaaagacatgctgctggaggtgaagaagagaatgcggactgagatggac atgggcctgaggaaacagacgcacgagaaggccgtagtcaagatgctcccctcgtttgtc cggagcactccagacgggaccgagcacggcgacttcttggcccttgatctgggaggaacg aatttccgtgtcctactggtgaaaatccgcagtgggaagaagaggacggtggagatgcac aacaagatctatgccattcccattgaaatcatgcagggcactggggaggagctgtttgac cacatcgtttcctgcatctccgacttcctggactacatggggatcaaaggccccagaatg cctctgggcttcacgttctcctttccctgcaagcagacaagcttggacgcgggaatcttg atcacctggacaaagggttttaaggcaaccgactgcgtggggaatgacgttgcaacctta ctaagagaagcaatcaaaaggagagaggaatttgacttggacgtggtggcggtggtcaat gacacggtgggcaccatgatgacctgtgcttatgaagagcctacctgcgaggttggactc atcgtagggaccggcagtaatgcctgctacatggaagaaatgaagaatgtcgagatgctg gagggggaccaggggcgaatgtgtatcaacatggagtggggtgcctttggggacaacggg tgtctagatgatatcagaacaatctatgacagactggtggatgaatattctctaaatgct ggaaaacaaaggtttgagaagatgattagtggtatgtacctgggtgagattgtccgcaac atcttgatcgacttcaccaagaagggcttcctcttccgagggcagatctctgagccgctg aagactcggggcatctttcagaccaaatatctctcccagattgagagtgaccggctggcg ctgctccaggtgcgggccatcctccagcagctgggcctgaacagcacctgcgacgacagt atcctcgtcaagacagtgtgcggggtggtgtccaggcgggccgcacagctgtgtggtgca ggcatggccgccgtggtggataagatccgtgagaacagaggcctggaccacctcagtgtg accgtgggtgtggacgggacgctctacaagcttcacccgcacttctcgagaatcatgcac caaaccgtgaaggaactgtcaccaaagtgtaacgtgtccttcctcctgtccgaagacggt agtggcaagggggctgcgctcatcacggccgtgggcgtccggctccgggaagaagcgagc agctaa

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