KEGG   Camelus dromedarius (Arabian camel): 105084839
Entry
105084839         CDS       T04642                                 
Symbol
DHFR
Name
(RefSeq) dihydrofolate reductase isoform X2
  KO
K00287  dihydrofolate reductase [EC:1.5.1.3]
Organism
cdk  Camelus dromedarius (Arabian camel)
Pathway
cdk00670  One carbon pool by folate
cdk00790  Folate biosynthesis
cdk01100  Metabolic pathways
cdk01240  Biosynthesis of cofactors
cdk01523  Antifolate resistance
cdk04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:cdk00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    105084839 (DHFR)
   00670 One carbon pool by folate
    105084839 (DHFR)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    105084839 (DHFR)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    105084839 (DHFR)
Enzymes [BR:cdk01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.3  dihydrofolate reductase
     105084839 (DHFR)
SSDB
Motif
Pfam: DHFR_1
Other DBs
NCBI-GeneID: 105084839
NCBI-ProteinID: XP_010973352
UniProt: A0A5N4EC62
LinkDB
Position
3
AA seq 187 aa
MVRPLNCIVAVSQNMGIGKNGDLPWPPLRNEFKYFQRMTTASSVEGKQNLVIMGRKTWFS
IPEKNRPLKDRINLVLSRELKEPPQGAHFLANSLDDALKLIEQPELTNKVDMVWIVGGSS
VYKEAMDKPGHLRLFVTRIMQEFESDMFFPEIDLEKYKLLSEYPGVPSDVQEEKGIKYKF
EVYEKNN
NT seq 564 nt   +upstreamnt  +downstreamnt
atggttcgtccgctgaactgcatcgttgctgtgtcccagaacatgggtatcggcaagaat
ggggacctgccctggcctccgctcaggaatgaattcaagtatttccagagaatgaccaca
gcctcttcagtagaaggtaagcaaaatttggtgattatgggtagaaagacctggttctcc
attccagagaagaatcgacctttaaaggacagaattaatttggttctcagtagagaactc
aaggaaccaccacaaggagctcattttcttgccaacagtctggatgatgccttaaaactt
attgagcaaccagaattaacaaataaagtggacatggtttggatagtgggaggcagttct
gtttataaggaagctatggacaagccaggccatcttagattatttgtgacaaggatcatg
caggagtttgagagtgacatgttttttccagaaattgatttggaaaaatataaacttctt
tcagaatatccaggtgttccttctgatgtccaggaggagaaaggcattaagtacaaattt
gaagtatatgaaaagaacaattaa

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