Camelus dromedarius (Arabian camel): 105088301 Help Entry 105088301         CDS       T04642                                  Symbol IRS1 Name (RefSeq) insulin receptor substrate 1   KO K16172   insulin receptor substrate 1 Organism cdk  Camelus dromedarius (Arabian camel) Pathway cdk04022   cGMP-PKG signaling pathway cdk04068   FoxO signaling pathway cdk04081   Hormone signaling cdk04140   Autophagy - animal cdk04150   mTOR signaling pathway cdk04151   PI3K-Akt signaling pathway cdk04152   AMPK signaling pathway cdk04211   Longevity regulating pathway cdk04213   Longevity regulating pathway - multiple species cdk04722   Neurotrophin signaling pathway cdk04910   Insulin signaling pathway cdk04920   Adipocytokine signaling pathway cdk04923   Regulation of lipolysis in adipocytes cdk04930   Type II diabetes mellitus cdk04931   Insulin resistance cdk04932   Non-alcoholic fatty liver disease cdk04935   Growth hormone synthesis, secretion and action cdk04960   Aldosterone-regulated sodium reabsorption cdk05010   Alzheimer disease cdk05206   MicroRNAs in cancer cdk05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:cdk00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     105088301 (IRS1)    04022 cGMP-PKG signaling pathway     105088301 (IRS1)    04151 PI3K-Akt signaling pathway     105088301 (IRS1)    04152 AMPK signaling pathway     105088301 (IRS1)    04150 mTOR signaling pathway     105088301 (IRS1)   09133 Signaling molecules and interaction    04081 Hormone signaling     105088301 (IRS1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     105088301 (IRS1)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     105088301 (IRS1)    04923 Regulation of lipolysis in adipocytes     105088301 (IRS1)    04920 Adipocytokine signaling pathway     105088301 (IRS1)    04935 Growth hormone synthesis, secretion and action     105088301 (IRS1)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     105088301 (IRS1)   09156 Nervous system    04722 Neurotrophin signaling pathway     105088301 (IRS1)   09149 Aging    04211 Longevity regulating pathway     105088301 (IRS1)    04213 Longevity regulating pathway - multiple species     105088301 (IRS1)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     105088301 (IRS1)   09164 Neurodegenerative disease    05010 Alzheimer disease     105088301 (IRS1)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     105088301 (IRS1)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     105088301 (IRS1)    04932 Non-alcoholic fatty liver disease     105088301 (IRS1)    04931 Insulin resistance     105088301 (IRS1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 Motif Other DBs NCBI-GeneID:  105088301 NCBI-ProteinID:  XP_031308149 LinkDB All DBs Position 5:complement(86427638..86486832) Genome browser AA seq 1240 aa AA seqDB search MASPPETDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAP KRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGH HDGAAAPGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLI GIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQV DDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLT RRSRTESITATSPASLVGGKQGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHR GSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSP SDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLAAPN GHYILPRGGNGHRYIPGAGLGTSPALTGDEAASAADLDNRFRKRTHSAGTSPTISHQKTP SQSSVASIEEYTEMMPAYPPGGGSGGRVPSYRHSAFVPTHSYPEEGLEMHPLERRGGHHR PDTSSLHTDDGYMPMSPGVAPVPGSRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPN GYMMMSPSGSCSPDLGGGPGSGGSGSGAAPSGSSYGKLWTNGVGGHHSHALPHPKLPVES SSGKLLSCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEL EESARHQHLRLSSSSGRLLYATAAEDSSSSTSSDSLGGGYCGARLEPSLPHLHHQVLQPH LPRKVDTAAQTNNRLARPTRLSLGDPKASTLPRAREQQPPPLLHPPEPKSPGEYVNIEFG SDQPGYLSGPVAPHSSPSVRCPSQLQPAPREEEAGAEEYMNMDLGPGRRATWQESAGVQP GRVGPAPPGAVSVCRPTRAVPSSRGDYMTMQVGCPHQSYVDTSPVAPISYADMRTGIVVE EASLPGATAAAPSSSSTTSASPAEPQGAGELAACSSLLGGPQGPGGPSAFTRVNLSPSRN QSAKVIRADPQGCRRRHSSETFSSTPSATRAGNTLPFGGGAAVGGSGGGSSSAEDVKRHS SASFENVWLRPGELGGAPKELAQVCGAAGGLENGLNYIDLDLVKDFKQRPQERPPQPQPP PPPPPHQPLGSGESSSTSRSSEDLSAYASISFQKQPEDLQ NT seq 3723 nt NT seq  +upstreamnt  +downstreamnt atggcgagccctcccgagaccgacggcttctcggacgtgcgcaaggtgggctacctgcgc aaacccaagagcatgcacaagcgcttcttcgtgctgcgggcggccagcgaggcggggggc ccggcgcgtctcgagtactacgagaacgagaagaagtggcggcacaagtcgagcgccccc aaacgctcgatccccctcgagagctgcttcaacatcaacaagcgggcggactccaagaac aagcacctggtagccctctacacccgggacgagcactttgccatcgcggcggacagcgag gcggagcaggacagctggtaccaggccctcctgcagctgcacaaccgagccaagggccac cacgacggggccgcggcccccggggcgggaggcggcgggggcagctgcagtggcagctct ggcctcggcgaggctggggaggacttgagctacggggacgtgcccccaggacccgccttc aaggaggtctggcaggtgatcctgaaacccaagggcctgggtcagacaaagaacctgatt ggcatctaccgcctctgcctgaccagcaagaccatcagctttgtgaagctgaactcggag gcggcggctgtggtactgcagctgatgaacatcaggcgctgtgggcactccgagaacttc ttcttcatcgaggtgggccgttccgcagtgacgggacccggggagttctggatgcaggtg gatgactctgtggtggcccagaacatgcatgagacaatcctggaggccatgcgggccatg agcgatgagtttcgacctcgaagcaagagccagtcctcctccaactgctccaaccccatc agtgtccccctgcgcaggcaccacctcaacaaccctccacccagccaggtagggctgacc cgccgctctcgcacagagagcatcactgccacctcccctgccagcttggtgggcgggaag cagggctccttccgcgtccgtgcctccagtgatggcgaaggcaccatgtctcgccccgcc tctgtggacggtagtcctgtaagtcctagcaccaacaggacccacgcccaccggcatcga ggcagctcccggctgcacccgcctctcaaccacagccgctctatccccatgccttcttct cgctgctcaccttctgccaccagcccggtcagtctgtcgtctagcagcaccagtggccac ggatccacctcggactgtctcttcccgcggcggtctagtgcttctgtgtccggttccccc agcgatggcggtttcatctcctcagatgagtatggctccagtccctgcgatttccgaagt tcctttcgtagtgtcactccggattccctgggccacaccccaccggcccgcggtgaggag gagctgagcaactacatctgcatgggaggcaaggggccctccaccctcgctgcccccaac ggtcactacattttgcctcggggtggcaacggtcaccgctacatcccaggagctggtttg gggacgagcccagccctgactggagatgaagcagccagtgccgcggatctggataatcgg ttccgaaagcgaactcactctgctggcacatcccctaccatttcccaccagaagacccca tcccagtcctctgtggcttccattgaggaatatacagagatgatgcctgcctacccgcca ggaggtggcagcggaggccgagtgcccagctaccggcactccgccttcgtgcccacccat tcctaccctgaggagggtctagaaatgcaccccctggagcggcgtgggggccaccaccgc ccagacacctccagtctccacaccgatgacggctacatgcccatgtccccaggggtggct ccagtgcccggcagccgaaagggcagtggagactacatgcccatgagccccaagagcgtg tctgccccacaacagattatcaaccccatcagacgccatcctcagagagtggaccccaat ggctacatgatgatgtccccaagcggcagctgctctcctgaccttggaggtgggcctggc agtggcggcagcggcagcggtgcagccccttctgggagcagctatggcaagctgtggacg aacggggtaggaggccaccactctcacgccctgccacaccccaaactccccgtggagagc agtagtggcaagctcttgtcttgtacaggtgactacatgaacatgtcgccagtgggggac tccaacaccagcagcccttccgactgctactatggccctgaggatccccagcacaagcca gtcctctcctactactccttgccaaggtcctttaagcacacccagcgcccgggagagctg gaggagagcgcccggcaccagcacctccgcctctcctccagctctggtcgactcctctat gccacagcggcagaagattcctcctcctccaccagcagcgacagcctgggcgggggatac tgtggggctaggctggagcccagcctcccgcatctccaccatcaggtcctgcagccccat ctgcctcgaaaggtggacacagctgcccagaccaacaaccgcctggcccggcccacgagg ctgtccctgggggatcccaaggccagcaccttacctcgggccagagagcagcagccgccg cccttgctgcaccctccggagcccaagagcccaggggaatatgtgaatattgaattcggg agcgatcagcccggctacttatctggcccagtggctccccacagctcgccttctgtcagg tgcccatcccagctccagccagctcccagagaggaagaggctggcgcggaagagtacatg aacatggacctggggcccggcaggagggccacctggcaggagagcgcaggggtccagccc gggagggtgggccccgccccccccggagctgttagcgtgtgccggccgacccgggcagtg cctagcagccggggtgactacatgaccatgcaggtgggctgcccccatcagagctacgtg gacacctcgccggttgcccccatcagctacgccgatatgcggaccggaatcgttgtggag gaggccagccttcccggggccacagcggccgcgccctcctcatcctccacgacctctgct tcccctgcagagcctcaaggagcaggggagctggcggcctgctcgtccctgctggggggc ccgcagggacctgggggcccgagcgccttcacgcgggtgaacctcagtcccagccgtaac cagagtgccaaagtgatccgtgccgacccgcaagggtgcaggaggaggcacagctccgag accttctcctcaacgcccagtgccactcgggcgggcaacaccctgcccttcggaggcggg gctgcagtcgggggcagtggtggtggcagcagcagcgctgaggatgtgaagcgccacagc tctgcttcctttgagaacgtgtggctgaggcctggggagctggggggagcccccaaggag ctggctcaagtgtgcggggcagccgggggtttggagaatggtcttaactacatagacctg gatctggtcaaggacttcaaacagcgccctcaggagcgaccccctcaaccgcagcctcct ccacccccgcccccccatcagcctctgggcagcggcgagagcagctccaccagccgctcc agcgaggatttaagcgcctatgccagcatcagtttccagaagcagccagaggacctccag tag

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