Camelus dromedarius (Arabian camel): 105101858 Help Entry 105101858         CDS       T04642                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism cdk  Camelus dromedarius (Arabian camel) Pathway cdk04062   Chemokine signaling pathway cdk04151   PI3K-Akt signaling pathway cdk04217   Necroptosis cdk04550   Signaling pathways regulating pluripotency of stem cells cdk04630   JAK-STAT signaling pathway cdk04658   Th1 and Th2 cell differentiation cdk04659   Th17 cell differentiation cdk05161   Hepatitis B cdk05162   Measles cdk05166   Human T-cell leukemia virus 1 infection cdk05169   Epstein-Barr virus infection cdk05200   Pathways in cancer cdk05203   Viral carcinogenesis cdk05223   Non-small cell lung cancer cdk05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:cdk00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105101858 (JAK3)    04151 PI3K-Akt signaling pathway     105101858 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     105101858 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     105101858 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     105101858 (JAK3)    04659 Th17 cell differentiation     105101858 (JAK3)    04062 Chemokine signaling pathway     105101858 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105101858 (JAK3)    05203 Viral carcinogenesis     105101858 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     105101858 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105101858 (JAK3)    05161 Hepatitis B     105101858 (JAK3)    05162 Measles     105101858 (JAK3)    05169 Epstein-Barr virus infection     105101858 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     105101858 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cdk01001]     105101858 (JAK3) Enzymes [BR:cdk01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      105101858 (JAK3) Protein kinases [BR:cdk01001]  Non-receptor tyrosine kinases   JAK family [OT]    105101858 (JAK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl Kdo ABC1 FERM_C_FAK1 Haspin_kinase Motif Other DBs NCBI-GeneID:  105101858 NCBI-ProteinID:  XP_031293460 LinkDB All DBs Position 22:complement(11932432..11948005) Genome browser AA seq 1104 aa AA seqDB search MAPPSEEMPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVRAAKA SGILPVYHSLFALATEDLSCWFPPSHIFSVEDVGTQVLVYRLRFYFPNWFGLEKCHRFGL RKDLACAILDLPVLEHLFAQHRNDLVSGCLPVGLSLKEQGECLSLAVLDLARMALEQAQR PEELLKTISYKVCLPPGLRDLIQGLSFVTRKRIRRTVRRALRRVAACQADRHSLMAKYIM DLERLDPGRAAETFRVGLPGTAGGQDAPGLLRVAGGSGIAWSPGEQEVLQPFCDFPEIVD ISIKQAPRFGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTTDSQHFFC KEVAPPRLLEEVAEQCYGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSFLLTICVQTP LGPDYKGCLIRCDPSGTVSLAGLGRPHSSLRELLAACWDSGLHVDGIELNLTFCCTPRPK EKSNLIVVRRGCSLPTSCPVQPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR HETVDGEARETEVLLKVMDVKHKNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSIMVQ EFVHLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA DGNPPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GVMMPISTLDPAKKLQFYEERQQLPAPKWMELALLIQQCMAYEPGQRPSFRAVIRDLNSL ITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR YDPLGDNTGALVAVKQLQHSGPEQQKDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRARLDAGRLLLFASQICKGMEYLGSRRCVHRDLAARNILVENE THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYSDKSCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPGEVHELMKLCWAP SPQDRPPFSALGPQLDALWSGSQG NT seq 3315 nt NT seq  +upstreamnt  +downstreamnt atggcacctccaagtgaggagatgcccttgatccctcagcgttcctgcagcctctcctct tcagaggctggcgccctgcacgtgctgctgccccctcggggccctggacccccacagcgc ctatccttctcttttggggaccactcagctgaagagctgtgtgttcgagctgctaaggcc agtggtatcctgcccgtgtaccactccctctttgctctggccacggaggacctatcctgt tggttccccccgagccacatcttctccgtggaagacgtgggcacccaggtccttgtctac aggctccgcttttacttccccaactggtttgggctagaaaagtgccaccgctttgggcta cgaaaggacttagcctgcgccatccttgacctgccagtcctggagcacctatttgctcag caccgaaatgacctggtgagcggctgcctcccagtgggcctcagcctcaaggagcagggt gagtgtctcagcttggctgtgctggacctggcccgcatggctctcgagcaggctcagcgg cccgaggagctgctgaagaccatcagctacaaggtctgcctgccccccggcctgcgcgac ctgatccagggcctgagtttcgtgacacgaaagcgtatccgaaggacagtgcgcagggct ttgcgccgcgtggccgcctgccaggctgacaggcattcactcatggccaagtacatcatg gatctcgaacggctggacccaggcagggccgccgagaccttccgcgtgggcctccccggg acggctggtggtcaggatgcgccagggctgctccgcgtggctggtggcagcggcatagcc tggagcccaggagaacaagaggtccttcagcccttctgcgactttccagaaattgtggat atcagcatcaagcaggccccgcgctttggcccggctggggagcaccgcctggtcaccgtc accaggacggacaaccagatcctggaggccgagttcccggggctgcccgccgccttgtcc ttcgtggcactcgtggatggctacttcaggctgaccaccgactcccagcacttcttctgc aaggaggtggcgccgccgcggctgctggaggaggtggctgagcagtgctatggccccatc accctggattttgccatcaacaaactcaagactgggggctcgcttcccggctcctacgtt ctccgtcgcagcccccaggattttgacagcttcctcctaactatctgtgtccagaccccc ctgggccctgattacaaaggctgcctcattcggtgtgacccttcgggaactgtctccctg gctggccttggccgtccccacagcagtcttcgagagctcctggcagcctgttgggatagt gggttgcatgtggatgggattgagctgaacctcaccttctgctgcacccccagacccaaa gaaaaatccaacctgatcgtggtccggagaggttgcagcctgcccacgtcatgccctgtt cagccccaatctcaatgccagctgagtcagatgacgtttcacaagatccctgctgacagc ctggagtggcatgagaatctgggtcacgggtctttcaccaagatttaccgcggctgtcga catgagaccgtggatggggaggcccgggagacagaggtgctgctcaaagtgatggatgtc aagcacaagaactgcatggagtcattcctggaagcagcgagcttgatgagccaagtgtca taccagcatcttgtgttgctccatggcgtgtgcatggctggagacagcatcatggtgcag gagtttgtacacctgggagcactggacacgtatctgcgcaagagtggccacctggtgcct gccagctggaagctacaggtgatcaaacagctggcctatgccctcaactatctggaagac aaaggtctccctcatggcaatgtctcagcccggaaagtgctcctggcccgggagggggct gatgggaacccacccttcatcaaactgagtgaccctggtgtcagccccactgtgctaagt ctggagatgctcactgacaggattccctgggtggcccctgagtgtctccaggaggcccga acacttggcttggaagctgacaagtggggctttggtgccacagtctgggaggtgttcagc ggtgtcatgatgcccatcagcaccctggatccagccaagaagctccagttttacgaggaa cgtcagcagctgcccgcccccaagtggatggagctggccctgctgatccaacagtgcatg gcgtacgagccgggccagaggccctccttccgtgctgtcatccgtgacctgaacagcctc atcacttcagattatgagctcctctcagaccccacacctggtgccttggcaccccgtgac gggctttggaatggtgcccagctctatgcctgccaggaccctaccatctttgaggagaga cacctcaagtatatctcacagctgggcaagggcaactttggcagcgtggaactatgtcgc tatgacccactgggcgacaacacaggcgccctagtggctgtgaagcagctgcagcacagt gggccagaacagcagaaggacttccagcgggagatccagatcctcaaagccctgcacagc gacttcattgtcaagtaccgaggtgtcagctatggtccaggccgccagagcctgcggctg gtcatggagtacctgcccagcggctgtctgcgcgacttcctgcagcggcaccgtgcccgc ctcgacgctggccgcctgctcctctttgcctcgcagatctgcaagggcatggagtaccta ggctcccgccgctgcgtgcaccgcgacctggcagcccgtaacatcctggtggagaacgag acgcacgtcaagatcgcagacttcggcctcgccaagcttctgccgctcgacaaagactac tacgtggtccgcgagcccggccaaagtcccatcttctggtatgccccagagtccctctca gataacatcttctcgcgccagtcggatgtctggagcttcggggtcgtcctgtatgagctc ttcacctacagtgacaagagctgtagcccctcagctgagttcctgcggatgatgggatgt gagcgagatgtcccagccctctgccgcctcctggagctgctggctgagggccagaggctg cccgcacctcctgcctgccctggtgaggttcatgagctcatgaagctatgctgggcccct agcccacaagaccggccaccattcagtgctctgggtccccagctggatgcactgtggagt ggaagccagggatag

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