Camelus dromedarius (Arabian camel): 105101867
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Entry
105101867 CDS
T04642
Symbol
PIK3R2
Name
(RefSeq) phosphatidylinositol 3-kinase regulatory subunit beta isoform X1
KO
K02649
phosphoinositide-3-kinase regulatory subunit alpha/beta/delta
Organism
cdk
Camelus dromedarius (Arabian camel)
Pathway
cdk01521
EGFR tyrosine kinase inhibitor resistance
cdk01522
Endocrine resistance
cdk01524
Platinum drug resistance
cdk04012
ErbB signaling pathway
cdk04014
Ras signaling pathway
cdk04015
Rap1 signaling pathway
cdk04024
cAMP signaling pathway
cdk04062
Chemokine signaling pathway
cdk04066
HIF-1 signaling pathway
cdk04068
FoxO signaling pathway
cdk04070
Phosphatidylinositol signaling system
cdk04071
Sphingolipid signaling pathway
cdk04072
Phospholipase D signaling pathway
cdk04081
Hormone signaling
cdk04140
Autophagy - animal
cdk04150
mTOR signaling pathway
cdk04151
PI3K-Akt signaling pathway
cdk04152
AMPK signaling pathway
cdk04210
Apoptosis
cdk04211
Longevity regulating pathway
cdk04213
Longevity regulating pathway - multiple species
cdk04218
Cellular senescence
cdk04360
Axon guidance
cdk04370
VEGF signaling pathway
cdk04380
Osteoclast differentiation
cdk04510
Focal adhesion
cdk04550
Signaling pathways regulating pluripotency of stem cells
cdk04611
Platelet activation
cdk04613
Neutrophil extracellular trap formation
cdk04620
Toll-like receptor signaling pathway
cdk04625
C-type lectin receptor signaling pathway
cdk04630
JAK-STAT signaling pathway
cdk04650
Natural killer cell mediated cytotoxicity
cdk04660
T cell receptor signaling pathway
cdk04662
B cell receptor signaling pathway
cdk04664
Fc epsilon RI signaling pathway
cdk04666
Fc gamma R-mediated phagocytosis
cdk04668
TNF signaling pathway
cdk04670
Leukocyte transendothelial migration
cdk04722
Neurotrophin signaling pathway
cdk04725
Cholinergic synapse
cdk04750
Inflammatory mediator regulation of TRP channels
cdk04810
Regulation of actin cytoskeleton
cdk04910
Insulin signaling pathway
cdk04914
Progesterone-mediated oocyte maturation
cdk04915
Estrogen signaling pathway
cdk04917
Prolactin signaling pathway
cdk04919
Thyroid hormone signaling pathway
cdk04923
Regulation of lipolysis in adipocytes
cdk04926
Relaxin signaling pathway
cdk04929
GnRH secretion
cdk04930
Type II diabetes mellitus
cdk04931
Insulin resistance
cdk04932
Non-alcoholic fatty liver disease
cdk04933
AGE-RAGE signaling pathway in diabetic complications
cdk04935
Growth hormone synthesis, secretion and action
cdk04960
Aldosterone-regulated sodium reabsorption
cdk04973
Carbohydrate digestion and absorption
cdk05010
Alzheimer disease
cdk05017
Spinocerebellar ataxia
cdk05020
Prion disease
cdk05100
Bacterial invasion of epithelial cells
cdk05135
Yersinia infection
cdk05142
Chagas disease
cdk05146
Amoebiasis
cdk05160
Hepatitis C
cdk05161
Hepatitis B
cdk05162
Measles
cdk05163
Human cytomegalovirus infection
cdk05164
Influenza A
cdk05165
Human papillomavirus infection
cdk05166
Human T-cell leukemia virus 1 infection
cdk05167
Kaposi sarcoma-associated herpesvirus infection
cdk05168
Herpes simplex virus 1 infection
cdk05169
Epstein-Barr virus infection
cdk05170
Human immunodeficiency virus 1 infection
cdk05171
Coronavirus disease - COVID-19
cdk05200
Pathways in cancer
cdk05203
Viral carcinogenesis
cdk05205
Proteoglycans in cancer
cdk05206
MicroRNAs in cancer
cdk05207
Chemical carcinogenesis - receptor activation
cdk05208
Chemical carcinogenesis - reactive oxygen species
cdk05210
Colorectal cancer
cdk05211
Renal cell carcinoma
cdk05212
Pancreatic cancer
cdk05213
Endometrial cancer
cdk05214
Glioma
cdk05215
Prostate cancer
cdk05218
Melanoma
cdk05220
Chronic myeloid leukemia
cdk05221
Acute myeloid leukemia
cdk05222
Small cell lung cancer
cdk05223
Non-small cell lung cancer
cdk05224
Breast cancer
cdk05225
Hepatocellular carcinoma
cdk05226
Gastric cancer
cdk05230
Central carbon metabolism in cancer
cdk05231
Choline metabolism in cancer
cdk05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
cdk05415
Diabetic cardiomyopathy
cdk05417
Lipid and atherosclerosis
cdk05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cdk00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
105101867 (PIK3R2)
04014 Ras signaling pathway
105101867 (PIK3R2)
04015 Rap1 signaling pathway
105101867 (PIK3R2)
04370 VEGF signaling pathway
105101867 (PIK3R2)
04630 JAK-STAT signaling pathway
105101867 (PIK3R2)
04668 TNF signaling pathway
105101867 (PIK3R2)
04066 HIF-1 signaling pathway
105101867 (PIK3R2)
04068 FoxO signaling pathway
105101867 (PIK3R2)
04070 Phosphatidylinositol signaling system
105101867 (PIK3R2)
04072 Phospholipase D signaling pathway
105101867 (PIK3R2)
04071 Sphingolipid signaling pathway
105101867 (PIK3R2)
04024 cAMP signaling pathway
105101867 (PIK3R2)
04151 PI3K-Akt signaling pathway
105101867 (PIK3R2)
04152 AMPK signaling pathway
105101867 (PIK3R2)
04150 mTOR signaling pathway
105101867 (PIK3R2)
09133 Signaling molecules and interaction
04081 Hormone signaling
105101867 (PIK3R2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105101867 (PIK3R2)
09143 Cell growth and death
04210 Apoptosis
105101867 (PIK3R2)
04218 Cellular senescence
105101867 (PIK3R2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
105101867 (PIK3R2)
04550 Signaling pathways regulating pluripotency of stem cells
105101867 (PIK3R2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
105101867 (PIK3R2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
105101867 (PIK3R2)
04613 Neutrophil extracellular trap formation
105101867 (PIK3R2)
04620 Toll-like receptor signaling pathway
105101867 (PIK3R2)
04625 C-type lectin receptor signaling pathway
105101867 (PIK3R2)
04650 Natural killer cell mediated cytotoxicity
105101867 (PIK3R2)
04660 T cell receptor signaling pathway
105101867 (PIK3R2)
04662 B cell receptor signaling pathway
105101867 (PIK3R2)
04664 Fc epsilon RI signaling pathway
105101867 (PIK3R2)
04666 Fc gamma R-mediated phagocytosis
105101867 (PIK3R2)
04670 Leukocyte transendothelial migration
105101867 (PIK3R2)
04062 Chemokine signaling pathway
105101867 (PIK3R2)
09152 Endocrine system
04910 Insulin signaling pathway
105101867 (PIK3R2)
04923 Regulation of lipolysis in adipocytes
105101867 (PIK3R2)
04929 GnRH secretion
105101867 (PIK3R2)
04915 Estrogen signaling pathway
105101867 (PIK3R2)
04914 Progesterone-mediated oocyte maturation
105101867 (PIK3R2)
04917 Prolactin signaling pathway
105101867 (PIK3R2)
04926 Relaxin signaling pathway
105101867 (PIK3R2)
04935 Growth hormone synthesis, secretion and action
105101867 (PIK3R2)
04919 Thyroid hormone signaling pathway
105101867 (PIK3R2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
105101867 (PIK3R2)
09155 Excretory system
04960 Aldosterone-regulated sodium reabsorption
105101867 (PIK3R2)
09156 Nervous system
04725 Cholinergic synapse
105101867 (PIK3R2)
04722 Neurotrophin signaling pathway
105101867 (PIK3R2)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
105101867 (PIK3R2)
09158 Development and regeneration
04360 Axon guidance
105101867 (PIK3R2)
04380 Osteoclast differentiation
105101867 (PIK3R2)
09149 Aging
04211 Longevity regulating pathway
105101867 (PIK3R2)
04213 Longevity regulating pathway - multiple species
105101867 (PIK3R2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
105101867 (PIK3R2)
05206 MicroRNAs in cancer
105101867 (PIK3R2)
05205 Proteoglycans in cancer
105101867 (PIK3R2)
05207 Chemical carcinogenesis - receptor activation
105101867 (PIK3R2)
05208 Chemical carcinogenesis - reactive oxygen species
105101867 (PIK3R2)
05203 Viral carcinogenesis
105101867 (PIK3R2)
05230 Central carbon metabolism in cancer
105101867 (PIK3R2)
05231 Choline metabolism in cancer
105101867 (PIK3R2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105101867 (PIK3R2)
09162 Cancer: specific types
05210 Colorectal cancer
105101867 (PIK3R2)
05212 Pancreatic cancer
105101867 (PIK3R2)
05225 Hepatocellular carcinoma
105101867 (PIK3R2)
05226 Gastric cancer
105101867 (PIK3R2)
05214 Glioma
105101867 (PIK3R2)
05221 Acute myeloid leukemia
105101867 (PIK3R2)
05220 Chronic myeloid leukemia
105101867 (PIK3R2)
05218 Melanoma
105101867 (PIK3R2)
05211 Renal cell carcinoma
105101867 (PIK3R2)
05215 Prostate cancer
105101867 (PIK3R2)
05213 Endometrial cancer
105101867 (PIK3R2)
05224 Breast cancer
105101867 (PIK3R2)
05222 Small cell lung cancer
105101867 (PIK3R2)
05223 Non-small cell lung cancer
105101867 (PIK3R2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
105101867 (PIK3R2)
05170 Human immunodeficiency virus 1 infection
105101867 (PIK3R2)
05161 Hepatitis B
105101867 (PIK3R2)
05160 Hepatitis C
105101867 (PIK3R2)
05171 Coronavirus disease - COVID-19
105101867 (PIK3R2)
05164 Influenza A
105101867 (PIK3R2)
05162 Measles
105101867 (PIK3R2)
05168 Herpes simplex virus 1 infection
105101867 (PIK3R2)
05163 Human cytomegalovirus infection
105101867 (PIK3R2)
05167 Kaposi sarcoma-associated herpesvirus infection
105101867 (PIK3R2)
05169 Epstein-Barr virus infection
105101867 (PIK3R2)
05165 Human papillomavirus infection
105101867 (PIK3R2)
09171 Infectious disease: bacterial
05135 Yersinia infection
105101867 (PIK3R2)
05100 Bacterial invasion of epithelial cells
105101867 (PIK3R2)
09174 Infectious disease: parasitic
05146 Amoebiasis
105101867 (PIK3R2)
05142 Chagas disease
105101867 (PIK3R2)
09164 Neurodegenerative disease
05010 Alzheimer disease
105101867 (PIK3R2)
05017 Spinocerebellar ataxia
105101867 (PIK3R2)
05020 Prion disease
105101867 (PIK3R2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
105101867 (PIK3R2)
05418 Fluid shear stress and atherosclerosis
105101867 (PIK3R2)
05415 Diabetic cardiomyopathy
105101867 (PIK3R2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
105101867 (PIK3R2)
04932 Non-alcoholic fatty liver disease
105101867 (PIK3R2)
04931 Insulin resistance
105101867 (PIK3R2)
04933 AGE-RAGE signaling pathway in diabetic complications
105101867 (PIK3R2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
105101867 (PIK3R2)
01524 Platinum drug resistance
105101867 (PIK3R2)
01522 Endocrine resistance
105101867 (PIK3R2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cdk04131
]
105101867 (PIK3R2)
Membrane trafficking [BR:
cdk04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
105101867 (PIK3R2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI3K_P85_iSH2
SH2
RhoGAP
SH3_1
SH2_1
Ribosomal_L22e
SH3_9
ATG11
Motif
Other DBs
NCBI-GeneID:
105101867
NCBI-ProteinID:
XP_031293488
LinkDB
All DBs
Position
22:12140372..12152887
Genome browser
AA seq
723 aa
AA seq
DB search
MAGAEGFQYRALYPFRRERPEDLELLPGDVLVVSRAALQALGVAEGSERCPQSVGWMPGL
NERTRQRGDFPGTYVEFLGPVALARPGPRPRGPRPLPARPRDGPPEPGLTLPDLPEQFSP
PDVAPPILVKLVEAIDRTGLDSYRPEPPAARTDWSLSDMEQWDAATLSDGVKGFLLALPS
PLVTPEAAAEAHRALREAAGPVGPVLEPPTLPLHHALTLRFLLQHLGRVARRAAAPGPVV
RALGATFGPLLLRAPPPSPPPGGAPDGTEPIPDFPALLVEKLLQEHLEEQEVAPPALPPK
PPKAKPASTGLANGGNPPSLQDAEWYWGDISREEVNEKLRDTPDGTFLVRDASSKIQGEY
TLTLRKGGNNKLIKVFHRDGHYGFSEPLTFCSVVDLITHYRHESLAQYNAKLDTRLLYPV
SKYQQDQIVKEDSVEAVGAQLKVYHQQYQDKSREYDQLYEEYTRTSQELQMKRTAIEAFN
ETIKIFEEQGQTQEKCSKEYLERFRREGNEKEMQRILLNSERLKSRIAEIHESRTKLEQE
LRVQASDNREIDKRMNSLKPDLMQLRKIRDQYLVWLTQKGARQKKINEWLGIKNETEDQY
SLMEDEDDLPHHEERTWYVGKINRTQAEEMLSGKRDGTFLIRESSQRGCYACSVVVDGDT
KHCVIYRTATGFGFAEPYNLYGSLKELVLHYQHASLVQHNDALTVTLAHPVRAPGPGPPP
AAR
NT seq
2172 nt
NT seq
+upstream
nt +downstream
nt
atggctggggctgagggcttccaataccgtgctctgtacccattccgccgggaacggcca
gaggacctggagctgctgccaggtgatgtccttgtggtgagccgggcggccctacaggca
ctgggcgtggctgagggcagcgagcgttgcccacagagtgtgggctggatgcctggcctc
aacgagcgtacacggcagcgcggcgacttccctggcacctacgttgagttcctggggcct
gtggccctggcccggcctggccctcgcccacgtggcccccgcccgctgcccgccaggccc
cgagatgggccccctgagccaggcctcacactccctgacctacccgagcagttctcccca
cctgatgtggcgccccctatcctggtgaagcttgtggaggccattgatcggacagggcta
gacagctacagacctgagccacctgccgcacgcacagactggtccctaagtgacatggag
cagtgggacgcggcaaccctgtcagatggcgtgaagggcttcctgctagcgctgccctct
ccccttgtgacacctgaggccgcggccgaagcacatcgagccctgcgggaggccgcaggg
cccgtggggccagtgctggagcccccgacgctgccactgcaccacgcgctcacgctgcgc
ttcctgctccagcatctgggccgggtggcccggcgcgccgcagcgccgggccccgtggtg
cgtgccctgggcgccaccttcgggccgctgctgctgcgtgcgccaccgccctcgccgcca
ccagggggcgcgcccgacgggactgagcccatccccgacttccctgctctgctggtggag
aagttgcttcaggaacatctggaggagcaggaggttgcgcccccagcactgccgcctaaa
ccccccaaggcaaagccggcctccacaggcctggccaatggggggaacccgccctccctg
caggatgctgaatggtactggggtgacatctccagggaggaggtaaacgagaaactccgg
gacacacctgatggtacctttctggtccgagatgcatccagcaagatccagggggagtac
acgctgacccttaggaaaggcgggaacaacaagctgatcaaggtcttccaccgagacggt
cactacggcttctcagagccgctcaccttctgctctgtcgtggacctcatcacccactac
cgccatgagtcactggcccagtacaatgccaagctggacactcggctcctctacccagtg
tccaagtaccagcaggaccagattgtcaaggaggacagcgtggaagcagtgggcgcccag
cttaaagtctatcaccagcagtaccaagacaagagccgcgagtacgaccagctctatgag
gagtacacacgcacctcccaggaactgcagatgaagcgcacagccatcgaggccttcaat
gagaccatcaagatctttgaagagcagggccagacgcaagagaagtgcagcaaggagtat
ctggagcgcttccggcgtgagggcaatgagaaggagatgcagaggatcctgctgaactcc
gagcggctcaagtctcgcattgctgagatccacgagagccgcacaaagctggagcaggag
ctacgggtgcaggcctctgacaaccgagagatcgacaagcgcatgaacagcctcaagcca
gacctcatgcagctgcgcaagatccgagaccagtaccttgtgtggctcactcagaaaggt
gcccggcagaagaaaatcaacgaatggttgggaatcaaaaacgagactgaggaccagtac
tcactgatggaagatgaggatgaccttccccaccatgaggaacgcacgtggtatgtaggc
aagatcaaccgcacacaagctgaggaaatgctgagtggcaagcgggatggcaccttcctc
atccgtgagagcagccagcgcggctgctacgcctgctccgtggtggtggatggtgacacc
aaacactgcgttatctaccgcacagccacgggcttcggctttgcagagccctataacttg
tacgggtcgctgaaggagctggtgctgcactaccagcatgcctcactggtgcagcacaac
gacgcgctcaccgtcacgctcgcccatcccgtgcgcgccccaggccccgggcccccacct
gccgcccgctga
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