KEGG   PATHWAY: cdm00740
Entry
cdm00740                    Pathway                                
Name
Riboflavin metabolism - Cronobacter dublinensis
Class
Metabolism; Metabolism of cofactors and vitamins
Pathway map
cdm00740  Riboflavin metabolism
cdm00740

Module
cdm_M00125  Riboflavin biosynthesis, plants and bacteria, GTP => riboflavin/FMN/FAD [PATH:cdm00740]
Other DBs
GO: 0006771
Organism
Cronobacter dublinensis [GN:cdm]
Gene
AFK67_10865  ribA; GTP cyclohydrolase [KO:K01497] [EC:3.5.4.25]
AFK67_04955  ribD; 5-amino-6-(5-phosphoribosylamino)uracil reductase [KO:K11752] [EC:3.5.4.26 1.1.1.193]
AFK67_06890  sugar phosphatase [KO:K20861] [EC:3.1.3.102 3.1.3.104]
AFK67_01375  flavin mononucleotide phosphatase [KO:K20862] [EC:3.1.3.102 3.1.3.104]
AFK67_17275  ribB; 3,4-dihydroxy-2-butanone 4-phosphate synthase [KO:K02858] [EC:4.1.99.12]
AFK67_04960  ribH; 6,7-dimethyl-8-ribityllumazine synthase [KO:K00794] [EC:2.5.1.78]
AFK67_09075  riboflavin synthase subunit alpha [KO:K00793] [EC:2.5.1.9]
AFK67_03365  FMN adenylyltransferase [KO:K11753] [EC:2.7.1.26 2.7.7.2]
AFK67_01520  fre; FMN reductase [KO:K05368] [EC:1.5.1.41]
AFK67_07365  NADPH-dependent FMN reductase [KO:K00299] [EC:1.5.1.38]
AFK67_13390  hydroxyethylthiazole kinase [KO:K00878] [EC:2.7.1.50]
AFK67_17245  nudF; ADP-ribose pyrophosphatase [KO:K01515] [EC:3.6.1.13 3.6.1.-]
AFK67_08160  phosphatase [KO:K12152] [EC:3.6.1.-]
AFK67_14335  3-octaprenyl-4-hydroxybenzoate carboxy-lyase [KO:K03186] [EC:2.5.1.129]
AFK67_16360  phenolic acid decarboxylase subunit B [KO:K03186] [EC:2.5.1.129]
Compound
C00016  FAD
C00044  GTP
C00061  FMN
C00199  D-Ribulose 5-phosphate
C00235  Dimethylallyl diphosphate
C00255  Riboflavin
C00474  Ribitol
C01007  Reduced riboflavin
C01268  5-Amino-6-(5'-phosphoribosylamino)uracil
C01304  2,5-Diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C01352  FADH2
C01390  Prenol
C01727  Lumichrome
C01847  Reduced FMN
C03114  Dimethylbenzimidazole
C04332  6,7-Dimethyl-8-(D-ribityl)lumazine
C04454  5-Amino-6-(5'-phospho-D-ribitylamino)uracil
C04732  5-Amino-6-(1-D-ribitylamino)uracil
C05995  7-Hydroxy-6-methyl-8-ribityllumazine
C15556  L-3,4-Dihydroxybutan-2-one 4-phosphate
C15563  2-Amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one
C18910  2,5-Diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one
C21214  Dimethylallyl phosphate
C21215  Prenylated FMNH2
Reference
PMID:12136096
  Authors
Vitreschak AG, Rodionov DA, Mironov AA, Gelfand MS.
  Title
Regulation of riboflavin biosynthesis and transport genes in bacteria by transcriptional and translational attenuation.
  Journal
Nucleic Acids Res 30:3141-51 (2002)
DOI:10.1093/nar/30.14.3141
Reference
PMID:11856310
  Authors
Fischer M, Haase I, Feicht R, Richter G, Gerhardt S, Changeux JP, Huber R, Bacher A.
  Title
Biosynthesis of riboflavin: 6,7-dimethyl-8-ribityllumazine synthase of Schizosaccharomyces pombe.
  Journal
Eur J Biochem 269:519-26 (2002)
DOI:10.1046/j.0014-2956.2001.02674.x
Reference
PMID:12867427
  Authors
Haase I, Fischer M, Bacher A, Schramek N.
  Title
Temperature-dependent presteady state kinetics of lumazine synthase from the hyperthermophilic eubacterium Aquifex aeolicus.
  Journal
J Biol Chem 278:37909-15 (2003)
DOI:10.1074/jbc.M303090200
Reference
PMID:16042598
  Authors
Fischer M, Romisch W, Illarionov B, Eisenreich W, Bacher A.
  Title
Structures and reaction mechanisms of riboflavin synthases of eubacterial and archaeal origin.
  Journal
Biochem Soc Trans 33:780-4 (2005)
DOI:10.1042/BST0330780
Related
pathway
cdm00030  Pentose phosphate pathway
cdm00040  Pentose and glucuronate interconversions
cdm00230  Purine metabolism
cdm00860  Porphyrin metabolism
cdm00900  Terpenoid backbone biosynthesis
KO pathway
ko00740   
LinkDB

DBGET integrated database retrieval system