Corynebacterium diphtheriae 241: CD241_1620
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Entry
CD241_1620 CDS
T01687
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase subunit E1
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
cdp
Corynebacterium diphtheriae 241
Pathway
cdp00010
Glycolysis / Gluconeogenesis
cdp00020
Citrate cycle (TCA cycle)
cdp00620
Pyruvate metabolism
cdp00785
Lipoic acid metabolism
cdp01100
Metabolic pathways
cdp01110
Biosynthesis of secondary metabolites
cdp01120
Microbial metabolism in diverse environments
cdp01200
Carbon metabolism
cdp01210
2-Oxocarboxylic acid metabolism
Module
cdp_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
cdp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
CD241_1620 (aceE)
00020 Citrate cycle (TCA cycle)
CD241_1620 (aceE)
00620 Pyruvate metabolism
CD241_1620 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
CD241_1620 (aceE)
Enzymes [BR:
cdp01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
CD241_1620 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Motif
Other DBs
NCBI-ProteinID:
AEX44677
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Position
1708114..1710849
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AA seq
911 aa
AA seq
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MSDPNEGMRPEDSNFAMIRDGVASYLNDADPEETREWMESLDGMLEGSSPDRARFLMLRL
LERASARRVPLPPMTSTDFVNTIPTTMEPEFPGDEEIEKRYRRWIRWNAAIMVHRAQRPG
IGVGGHISTYAGAAPLYEVGFNHFFRGKDHPGGGDHVFFQGHASPGMYARAFMEGRLTED
DLDGFRQEVSRPQGGLPSYPHPHGMKDFWEFPTVSMGLGPMDAIYQARFNRYLHNRGIKD
TSQQHVWAFLGDGEMDEPESRGLIQMAALNNLDNLTFVVNCNLQRLDGPVRGNTKIIQEL
ESFFRGAGWSVIKVVWGREWDQLFEADKDGALVDLMNTTSDGDFQTFKANDGAYVREHFF
NRDPRTAKLVEDWSDEDIWKLRRGGHDYRKIYAAFQRALETKDRPTVILAHTIKGYGLGH
NFEGRNATHQMKKLTLDDLKQFRDKQGVPITDEELEKDPYLPPYYHPGEDAPEIKYLLER
RKSLGGFVPERRESYTPLHVPELDKLRSLRKGSGKQQVATTMAVVRAFKELMRDPELGKR
IVPIIPDEARTFGMDSWFPTMKIYNPHGQNYVPVDHDLMLSYREAKDGQILHEGINEAGS
TASFIAAATSYATHGEAMIPLYIFYSMFGFQRTGDSFWAAGDQMARGFILGATAGRTTLT
GEGLQHMDGHSQILASTNPAVVSYDPAFSYEIAHLLREGIDRMYGPGRGEDVMYYLTIYN
EPISQPAEPEDLDVEGLHKGVYLYEKADGGEHEVSLLASGIGMQQALRAKEILRDEFSIG
ANIFSVTSWVELAREGHAKEREALRNPGIEQEEAFATTQLKKGSGPYIAVSDFATDLQEQ
IRRFVPGDYTTLGADGFGFSDTRPAARRFFNIDAESVVVAALNGLVKQGKIDRSVAAEAA
QRFNLTDPTKA
NT seq
2736 nt
NT seq
+upstream
nt +downstream
nt
atgtcagaccctaatgagggtatgcgccctgaagacagcaacttcgcgatgatccgcgac
ggtgttgcttcgtatctcaacgacgccgacccagaagagactcgcgaatggatggaatct
ctcgatggcatgctcgagggttccagtcccgatcgtgcccgattcctgatgctgcgtctc
ctcgagcgcgcttcggcccgtcgcgttccactaccaccgatgacgtcgacagactttgtc
aacaccatccccaccacgatggaacctgaattccccggtgacgaggaaattgagaaacgc
taccgtcgttggatccgctggaatgctgccatcatggttcaccgcgcccagcgcccaggc
attggcgttggtggacacatctccacctacgctggtgcagcaccactgtatgaagtcggc
ttcaaccacttcttccgcggcaaggaccacccaggtggtggcgaccatgtgttcttccaa
ggccacgcttccccaggtatgtatgcccgtgcattcatggaaggtcgtctgaccgaagac
gacctcgatggcttccgccaagaagtatcgcgtccacaggggggactcccctcctacccc
caccctcacggtatgaaggacttctgggagttcccgaccgtgtcaatgggccttggccca
atggacgctatttaccaagcacgctttaaccgctaccttcacaaccgcggcatcaaggac
acctcacagcagcacgtctgggcgttccttggcgacggcgaaatggatgagccagaatct
cgcggcctcattcagatggcagcgttgaataacttggacaacctgaccttcgttgttaac
tgcaacttgcagcgtctcgacggccctgttcgcggtaacaccaagatcattcaagagctg
gagtccttcttccgcggcgccggctggtctgttatcaaggttgtttggggacgcgagtgg
gatcagctcttcgaagctgataaggatggtgctctcgtcgacctcatgaataccacctct
gatggtgacttccagacctttaaggctaacgacggcgcctacgtgcgcgagcacttcttc
aaccgcgatccacgcaccgccaagcttgtcgaagactggtcggatgaagacatctggaag
ctgcgccgcggtggtcacgactaccgcaagatctacgctgcattccagcgcgcgcttgag
acaaaggatcgcccaaccgtgattcttgctcacaccattaagggctacggcttgggccac
aacttcgagggccgcaatgccacccaccagatgaagaagctcactctggacgatctcaag
cagttccgcgataagcagggcgtaccaattaccgacgaagaattggaaaaggatccatat
cttcctccgtactaccacccaggcgaggatgccccagagatcaagtacctcttggagcgt
cgtaagtctttgggcggattcgtaccggagcgtcgcgaatcctacaccccgctgcatgtc
cccgagctcgacaagctccgcagccttcgtaaaggctccggcaagcagcaagtcgccacc
actatggccgtggttcgcgccttcaaggaactcatgcgcgacccagagctgggcaagcgc
atcgtcccgatcattcctgacgaggctcgtaccttcggcatggactcatggttcccaacc
atgaagatctacaacccacatggtcaaaactatgtgccagtagaccatgacctcatgctt
tcctaccgtgaggccaaggacggccaaatcctccacgagggcatcaacgaagccggatct
accgcttccttcattgctgcagctacgtcctacgccacccacggcgaagccatgatcccg
ctgtacatcttctactcgatgttcggtttccagcgcactggcgattccttctgggcagca
ggcgaccaaatggcacgtggcttcatcttgggcgcaaccgccggtcgtacaaccttgaca
ggcgaaggcctccagcacatggatggtcactcccagatcttggcctcgaccaacccagcg
gtcgtttcctacgacccagcattctcctacgagattgcccaccttctgcgcgaaggtatc
gaccgcatgtacggcccaggccgtggtgaggacgtgatgtactacctcaccatctacaac
gagccaatttcacagccagccgagccagaggacttggacgttgagggcctacacaagggc
gtttacctttacgaaaaggcagacggtggcgagcacgaggtgtcccttttggcgtccggc
attggcatgcaacaagcactgcgcgccaaagagattcttcgcgacgagttcagcatcggc
gctaacatcttctcggttacctcttgggtagagttggcacgcgaaggacacgccaaggaa
cgtgaggcactgcgcaacccaggaattgagcaggaagaggcgtttgccaccacccaactc
aagaagggctccggaccgtacatcgccgtttccgactttgctaccgatctgcaagaacag
atccgccgctttgtcccaggcgactacaccaccttgggcgccgacggcttcggcttctcc
gatacccgcccagccgcccgtcgcttcttcaacatcgatgccgagtccgttgttgtcgca
gcactgaatggcttagtaaagcaaggcaagattgatcgcagcgttgcagccgaagcagct
cagcgtttcaacctcaccgacccaaccaaagcttaa
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