Candida dubliniensis: CD36_40210
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Entry
CD36_40210 CDS
T01140
Symbol
HIS4
Name
(RefSeq) histidine biosynthesis trifunctional protein [includes: phosphoribosyl-amp cyclohydrolase ; phosphoribosyl-atp pyrophosphohydrolase ; histidinol dehydrogenase (hdh)], putative
KO
K14152
phosphoribosyl-ATP pyrophosphohydrolase / phosphoribosyl-AMP cyclohydrolase / histidinol dehydrogenase [EC:
3.6.1.31
3.5.4.19
1.1.1.23
]
Organism
cdu
Candida dubliniensis
Pathway
cdu00340
Histidine metabolism
cdu01100
Metabolic pathways
cdu01110
Biosynthesis of secondary metabolites
cdu01230
Biosynthesis of amino acids
Module
cdu_M00026
Histidine biosynthesis, PRPP => histidine
Brite
KEGG Orthology (KO) [BR:
cdu00001
]
09100 Metabolism
09105 Amino acid metabolism
00340 Histidine metabolism
CD36_40210 (HIS4)
Enzymes [BR:
cdu01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.23 histidinol dehydrogenase
CD36_40210 (HIS4)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.4 In cyclic amidines
3.5.4.19 phosphoribosyl-AMP cyclohydrolase
CD36_40210 (HIS4)
3.6 Acting on acid anhydrides
3.6.1 In phosphorus-containing anhydrides
3.6.1.31 phosphoribosyl-ATP diphosphatase
CD36_40210 (HIS4)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Histidinol_dh
PRA-PH
PRA-CH
Motif
Other DBs
NCBI-GeneID:
8047509
NCBI-ProteinID:
XP_002419693
UniProt:
B9WF89
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Position
4:complement(29808..32315)
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AA seq
835 aa
AA seq
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MTFPVLPVISSPEDRESINEFSLVGQVIFPIESVSIKKHFIHQFPHDVDIFVNAIDNASI
DQIVELLNVGIKQVFVNETQYREAIEAGLPSARFVVSVDVPSAELVASEASFVVTKPFPE
GNLKEYNANENRVLYIKSDFTQDEAIELAKNYIPVIPSSKLSVKREEKNKISISAVFVST
LTTDRPDGLYTTLITTPSPSYTALGIVYSSKDSIVAAIEEKVGVYQSRKRRDELWYKGKT
SGATQKLVKLSKDCDSDVIQFMVEPRTGYGFCHRETKFTCFGDDMADSPARGLPKLDSTL
QDRLENAPEGSYTKRLFDDEKLLIAKLKEELDELIEAKSKEEIAWECADLVYFAMVWCIK
HGVRLADVEKNLDVKSLKVSRRKGDAKPKYQEPTTNSSYKLEIVSIDDAAAVERAMTRPV
QKTADIMKLVLPIIEKVKSDGDKALIELTSKFDGVKLDTPVLQAPFPAESMDISEEMKAA
IDLSMQNIEKFHAAQLPKEKVMTVETCPGVFCSRFAKPIENVGLYVPGGTAVLPSTAMML
GVPAKVAGCKNIIIASPPSRATGKLTPEVVYVAHKLGAKCIVMAGGAQAVTAMAYGTESV
LKCDKILGPGNQFVTAAKMYVQNDTQALCSIDMPAGPSEVLVIADCNADADFVASDLLSQ
AEHGVDSQVILIGVGLSDEKLNEFQNAVEKQAQVLPRKEIVAKCLAHSYILLAKTYQEAF
DLSNQYAPEHLILQIDDAPSYVPDMIENAGSVFVGALSPESCGDYSSGTNHTLPTYGYAR
QYSGVNTATFQKFITSQEVTEDGLKNIGKAVMELARVEGLEAHRRAVEIRMDRIT
NT seq
2508 nt
NT seq
+upstream
nt +downstream
nt
atgactttccctgttttgcctgttatttcttctcccgaagatagagaatcaattaatgag
ttttctttagtgggtcaagtaattttcccaatagaaagtgttagtatcaagaaacacttt
attcatcaatttccacatgacgtggatatttttgtaaatgctattgataatgccagtatt
gaccaaattgttgagttgttgaacgttgggatcaagcaggtgtttgttaatgagactcaa
tatcgtgaagctattgaagcaggcttaccaagtgctagatttgttgtgtctgttgatgtc
ccaagtgctgaattagtggcatctgaagcatcctttgttgttactaaaccatttcctgag
gggaatttgaaagaatataatgcgaatgaaaacagggttttatatatcaaatctgatttc
acacaggatgaggccattgaattggctaaaaactatattccagtgattccaagctcgaaa
ttgtctgtcaaacgtgaagaaaagaacaagatatcaatttctgctgtgtttgttagtaca
ttgactaccgacagaccagatgggttgtacaccacattaatcacaacgccatccccttct
tatacggcattgggtatagtgtattcctccaaggactctatagttgctgcaattgaagag
aaagttggggtttatcaatcacgtaaacgcagagatgaattatggtacaagggcaaaacc
agtggtgctacccagaaattagttaagttatccaaggattgtgattctgatgtgattcag
tttatggtagaaccacgaactggctatgggttctgccaccgtgaaaccaaatttacatgt
tttggtgatgatatggcagactctccagctagaggattgcccaaattagatagtactttg
caagacagattagaaaatgcacccgagggatcctatactaaacgtttatttgatgacgaa
aaattattgattgccaaattgaaggaagagttggatgaattgattgaagccaagtcgaag
gaggaaattgcttgggaatgtgccgatttggtttattttgccatggtctggtgcatcaaa
catggagtgagattggctgatgttgaaaagaatttggacgtaaagtccttgaaagtttcc
agaagaaaaggagacgccaagcctaagtaccaagagcctactaccaatagcagctataag
ttggagattgttagcattgatgatgctgctgctgttgagcgtgcaatgacaagacctgtt
cagaagactgcagacattatgaaacttgtgcttcctattattgaaaaagtgaaatctgat
ggtgacaaagctcttattgagttgacatccaagtttgatggtgtgaaacttgacacacct
gttttacaagctccgttccctgctgagctgatggatatttccgaagaaatgaaagctgct
attgacttgtcaatgcagaatatcgaaaaattccatgctgcacaattacccaaggaaaag
gttatgacggtagaaacatgtcctggtgtgttctgttctagatttgccaagccgattgaa
aatgttggattgtatgttccaggtggtacagcagtattaccttctacggcaatgatgttg
ggtgttccagcaaaagttgctgggtgtaagaatattataattgcgtctcctccgtcacgt
gctacagggaagttgacgccagaagttgtctatgttgcgcacaaattgggagcaaagtgt
attgttatggcaggtggtgctcaagcagttacggcaatggcatatggtactgaaagtgtg
ctcaagtgtgacaagatcttgggtcccggaaaccagtttgttactgctgccaagatgtat
gttcagaatgatacccaagcattatgttcaattgatatgccagcggggccatctgaggtt
ttggttattgcagattgcaatgccgatgctgactttgttgctagtgatttgctttcacaa
gctgagcatggtgtagactctcaggtaattcttattggtgttggattgagcgatgagaaa
ttgaatgagttccagaatgcagtagagaaacaagcccaagtgttgccaagaaaggagatt
gttgctaaatgtttggcccattcatacattttgttggctaaaacataccaagaagccttt
gatttgtcgaatcaatatgctcctgaacatttgatattacaaatcgacgatgctccatct
tatgttcctgatatgattgagaatgccggttcagtttttgttggagcattgtcacctgaa
tcctgtggggattactcaagtgggactaaccacactttgccaacgtatggttacgccaga
caatattctggagtcaatactgctactttccagaagtttattacttctcaagaagttaca
gaagacgggcttaagaatatcggcaaagcggtaatggaattagcaagagttgaggggttg
gaagctcacagaagagcagttgaaatcagaatggataggattacatag
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