Corynebacterium diphtheriae PW8: CDPW8_1238
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Entry
CDPW8_1238 CDS
T01701
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate-homocysteinemethyltransferase
KO
K00548
5-methyltetrahydrofolate--homocysteine methyltransferase [EC:
2.1.1.13
]
Organism
cdw
Corynebacterium diphtheriae PW8
Pathway
cdw00270
Cysteine and methionine metabolism
cdw00450
Selenocompound metabolism
cdw00670
One carbon pool by folate
cdw01100
Metabolic pathways
cdw01110
Biosynthesis of secondary metabolites
cdw01230
Biosynthesis of amino acids
cdw04980
Cobalamin transport and metabolism
cdw04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
cdw00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
CDPW8_1238 (metH)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
CDPW8_1238 (metH)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
CDPW8_1238 (metH)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
CDPW8_1238 (metH)
04980 Cobalamin transport and metabolism
CDPW8_1238 (metH)
Enzymes [BR:
cdw01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.13 methionine synthase
CDPW8_1238 (metH)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
S-methyl_trans
Pterin_bind
Met_synt_B12
B12-binding
B12-binding_2
Motif
Other DBs
NCBI-ProteinID:
AEX69893
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Position
complement(1281216..1284818)
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AA seq
1200 aa
AA seq
DB search
MNTATPQFKTAFLDAMKNRVLIGDGAMGTQLQGFDLDVDSDFLGLEGCNEILNHTRPDVV
SAIHRAYFEAGADLVETNTFGCNLPNLADYDIADRCKELAFKGVKIAREVADELGLSADG
TPRFVLGSMGPGTKLPSLGHAPYEALKNHYTEASLGMIEGGADAILVETAQDLLQVKAAV
HGCQTAFETSGIQLPIVCHVTVETTGTMLLGSEIGAALTAIEPLNVDMIGLNCATGPDEM
SEHLRYLSRNAHIPVSVMPNAGLPILGKNGAEYPLTEQELASALRGFVEEYGLSMVGGCC
GTTPTHIREVRKAVLGDSEHQPALQAERNPDVGDAVSSLYTSVNLTQDTGITMIGERTNA
NGSKAFREAMLVGDLEKCVDIAKQQTRDGAHMLDLCVDYVGRDGTADMAQLASLLATSST
LPIMIDSTEPDVIQVGLEHLGGRCAVNSVNFEDGDGPNSRYQRIMRLVKRHGAAVVALTI
DEEGQARTAEKKIEIAERLIADITSTWGLDESDIIVDTLTFPISTGQEETRRDGIETIEA
IRELKKRHPKIHTTLGLSNISFGLNPAARQVLNSVFLNECIEAGLDSAIAHSSKIVPMNR
IDEEQRRVALDMVYDRRSEGYDPLQTFMRLFEGVSAASASDARAEALAAMPLFERIAQRI
IDGEKAGFEDDLDAGMKEKEPLQIINEDLLEGMKTVGDLFGSGQMQLPFVLQSAETMKHA
VAYLEQFIEADEDAGDGNGTIVIATVKGDVHDIGKNLVDIILSNNGFNVVNIGIKQPIAN
ILEAAEKHKADAIGMSGLLVKSTVIMKENLQEMNQAQKSDYPVILGGAALTRAYVEDDLT
EVYEGNVHYAKDAFESLRLMQEFMAEARGERLDPQSPEALAAAKKKAERKARRERSKQIV
AQRKAKEIPIEVPERSEVAADVPIATPPFWGTRIVKGINLSEYLPLLDERALFVGRWGLK
ATRGGEGPSYEELVETEGRPRLRYWIDRLKAEKILDHAAVVYGYFPAVSEGDTVILLESP
DPTSAEVARFDFPRQQRGKFLCVADFIRSREHAIKTKTVDVFPLQLVTMGQPIADFANVL
FADNNYRDYLEVHGVGVQLTEALAEYWHARIRHELSLSDGSHAGDEDSADLQEFFNLKYR
GARYSFGYGSCPNLEDRETLVDLLDSSRIGVDISEEFQLHPEQSTDAFVLYHPEAKYFNV
NT seq
3603 nt
NT seq
+upstream
nt +downstream
nt
atgaatactgccacgccccaatttaaaactgcatttctcgacgctatgaaaaatcgcgtt
ctgatcggtgatggagcaatgggtacccagctccaaggattcgatcttgacgtcgattcc
gattttctaggtctcgagggctgtaacgaaattcttaatcacactcggccagatgttgtt
tctgcaatccaccgtgcctattttgaagcgggcgccgacttggttgaaacgaatactttt
ggttgcaacctacccaatttggccgattatgacattgcagatcgatgcaaggaactcgca
ttcaaaggtgtgaaaatcgcccgagaagttgcggatgaactgggactcagtgctgatggc
acaccacgcttcgttctaggttcaatgggacctggaacgaagttgccttcgcttggacac
gcaccttatgaagcgttgaaaaatcactacaccgaagcctcacttggcatgatcgaaggc
ggcgccgatgcgattttggtcgaaactgcccaagatttgcttcaggtaaaagcagctgta
catggttgccaaactgcatttgaaacttctggcattcagcttcccattgtttgtcacgtt
acggttgaaactactggtaccatgctcctaggttccgaaatcggtgctgcacttacggca
attgagccactcaatgtggacatgattggtcttaactgtgctactggcccagacgaaatg
agcgagcaccttcgatacttgtctcgcaatgctcacattccggtttcagtcatgcccaat
gccggtttgcccatcctcggtaaaaatggtgctgaatacccactaactgaacaagagctc
gcaagcgcactgagaggatttgttgaagaatacgggctcagcatggtgggaggctgctgt
ggtacaacgcctactcatattcgtgaagtacgtaaggctgtacttggcgatagcgagcat
caaccggcacttcaggctgagagaaatcccgatgtcggagatgcagtatcgagtctctac
accagtgtgaatctcacgcaagatactggcatcaccatgattggtgagcgaacgaatgcc
aatggttctaaagctttccgcgaggccatgcttgtaggtgatcttgaaaaatgtgtggat
attgctaagcaacaaactcgcgatggcgcccacatgcttgatttatgcgttgattatgtg
ggccgtgacggcacagccgatatggcccagctggcttcactgctagcaaccagctcgaca
cttcccatcatgattgattccactgagccggatgtaatccaagtaggactcgaacattta
ggtggtcgatgcgcagtaaactctgtgaactttgaagacggcgatggcccaaattctcgc
tatcaacgcattatgcgattagtcaaacgccatggagctgctgtcgtcgctctcaccatc
gatgaagaaggtcaagctcgcactgccgaaaagaaaattgaaattgccgaacggctcata
gcggacattacgtcgacatggggattagacgaaagcgacattatcgtcgatacgcttact
ttcccgatttcaaccggccaagaagaaacgcgtcgagacggtatcgaaactatcgaggca
attcgtgagcttaaaaagcgtcatcccaaaattcacaccaccttgggcctatctaacatc
tcttttggactgaacccagctgcacgtcaggttctcaattccgtatttttgaacgagtgc
attgaagcaggactagattcggctattgcacattcgtcaaagattgttcctatgaatcgt
atcgatgaggaacagcgacgggttgctctcgacatggtgtacgaccgaaggtctgaaggc
tatgacccgcttcaaactttcatgcgcctatttgaaggtgtatctgcagcaagtgcgagc
gatgcccgcgcagaagcattagcagctatgccgttattcgagcgaatcgctcaacgtatt
attgatggcgaaaaggccggtttcgaggatgacctcgatgcaggtatgaaagaaaaagaa
ccgctccaaattatcaacgaggatctcctagaggggatgaaaaccgttggtgatctcttt
ggatcaggccaaatgcaattgcccttcgtcctgcaatctgccgagacgatgaagcatgca
gtggcttatctcgagcagttcatagaagcggatgaagatgccggcgatggtaacggaaca
attgtcatcgcaacagtgaaaggtgacgtccacgacatcggaaagaaccttgtcgacatt
attctttcaaataatggattcaatgttgtcaacattggtatcaagcaacctattgcaaac
atcctagaggctgcagaaaaacacaaagcagatgctatcggcatgtctgggctattggta
aaatctaccgtgatcatgaaggaaaaccttcaagaaatgaaccaggcacaaaaatctgac
tatccagtcattcttggtggtgcagcgcttacgcgagcctatgtagaagatgacctcacc
gaggtgtacgaaggtaatgttcactatgcaaaagatgcattcgaatcacttcgcctaatg
caagaatttatggctgaagctaggggagagcgtctcgatccacagtcgccagaagctctt
gcggccgccaagaaaaaagctgagagaaaagctcgtcgagaacgttcaaagcaaattgtc
gcgcaacgcaaagcaaaggaaattcctatcgaggttccggaacgatccgaagttgcagct
gacgtgccaattgccacacctcctttctggggaacacgaattgttaaaggcatcaattta
tccgaatacctgccgcttctcgacgaacgcgcgctgtttgtgggtcgttggggcttaaaa
gcgactcgcggtggagagggcccaagttatgaagaacttgtagaaactgaaggtcgtcca
cggctgcggtactggattgatagactcaaagctgaaaaaatacttgaccacgccgctgtc
gtgtacggatatttcccagcagtttccgaaggcgatacggtcattcttcttgaatcacca
gaccctacttctgcagaggtagcacgatttgattttcctcgacaacagcgtggaaagttc
ctttgtgtagctgacttcattagatcccgtgagcacgctatcaagaccaagacggtagac
gtattcccgctgcaattggtaactatgggacagccgattgcagactttgccaatgtcctt
tttgctgataataattaccgagactatctcgaagtacatggtgtcggtgtgcaacttaca
gaagcacttgcggagtattggcatgcccgtatccgccacgaattgtcactttccgatgga
tctcatgcaggtgacgaagattccgctgatctgcaggaattctttaatcttaaataccga
ggtgctcgttattcctttggttatggttcctgcccaaatctcgaagatcgcgaaaccttg
gtagatttgcttgactcaagtcggattggcgtagatatttcagaagagtttcaactgcac
cctgagcaatcaacagatgcatttgtgttgtatcacccagaagcaaaatacttcaatgtg
taa
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