KEGG   Corynebacterium diphtheriae PW8: CDPW8_1238
Entry
CDPW8_1238        CDS       T01701                                 
Symbol
metH
Name
(GenBank) 5-methyltetrahydrofolate-homocysteinemethyltransferase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
cdw  Corynebacterium diphtheriae PW8
Pathway
cdw00270  Cysteine and methionine metabolism
cdw00450  Selenocompound metabolism
cdw00670  One carbon pool by folate
cdw01100  Metabolic pathways
cdw01110  Biosynthesis of secondary metabolites
cdw01230  Biosynthesis of amino acids
cdw04980  Cobalamin transport and metabolism
cdw04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:cdw00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    CDPW8_1238 (metH)
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    CDPW8_1238 (metH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CDPW8_1238 (metH)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    CDPW8_1238 (metH)
   04980 Cobalamin transport and metabolism
    CDPW8_1238 (metH)
Enzymes [BR:cdw01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     CDPW8_1238 (metH)
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding B12-binding_2
Other DBs
NCBI-ProteinID: AEX69893
LinkDB
Position
complement(1281216..1284818)
AA seq 1200 aa
MNTATPQFKTAFLDAMKNRVLIGDGAMGTQLQGFDLDVDSDFLGLEGCNEILNHTRPDVV
SAIHRAYFEAGADLVETNTFGCNLPNLADYDIADRCKELAFKGVKIAREVADELGLSADG
TPRFVLGSMGPGTKLPSLGHAPYEALKNHYTEASLGMIEGGADAILVETAQDLLQVKAAV
HGCQTAFETSGIQLPIVCHVTVETTGTMLLGSEIGAALTAIEPLNVDMIGLNCATGPDEM
SEHLRYLSRNAHIPVSVMPNAGLPILGKNGAEYPLTEQELASALRGFVEEYGLSMVGGCC
GTTPTHIREVRKAVLGDSEHQPALQAERNPDVGDAVSSLYTSVNLTQDTGITMIGERTNA
NGSKAFREAMLVGDLEKCVDIAKQQTRDGAHMLDLCVDYVGRDGTADMAQLASLLATSST
LPIMIDSTEPDVIQVGLEHLGGRCAVNSVNFEDGDGPNSRYQRIMRLVKRHGAAVVALTI
DEEGQARTAEKKIEIAERLIADITSTWGLDESDIIVDTLTFPISTGQEETRRDGIETIEA
IRELKKRHPKIHTTLGLSNISFGLNPAARQVLNSVFLNECIEAGLDSAIAHSSKIVPMNR
IDEEQRRVALDMVYDRRSEGYDPLQTFMRLFEGVSAASASDARAEALAAMPLFERIAQRI
IDGEKAGFEDDLDAGMKEKEPLQIINEDLLEGMKTVGDLFGSGQMQLPFVLQSAETMKHA
VAYLEQFIEADEDAGDGNGTIVIATVKGDVHDIGKNLVDIILSNNGFNVVNIGIKQPIAN
ILEAAEKHKADAIGMSGLLVKSTVIMKENLQEMNQAQKSDYPVILGGAALTRAYVEDDLT
EVYEGNVHYAKDAFESLRLMQEFMAEARGERLDPQSPEALAAAKKKAERKARRERSKQIV
AQRKAKEIPIEVPERSEVAADVPIATPPFWGTRIVKGINLSEYLPLLDERALFVGRWGLK
ATRGGEGPSYEELVETEGRPRLRYWIDRLKAEKILDHAAVVYGYFPAVSEGDTVILLESP
DPTSAEVARFDFPRQQRGKFLCVADFIRSREHAIKTKTVDVFPLQLVTMGQPIADFANVL
FADNNYRDYLEVHGVGVQLTEALAEYWHARIRHELSLSDGSHAGDEDSADLQEFFNLKYR
GARYSFGYGSCPNLEDRETLVDLLDSSRIGVDISEEFQLHPEQSTDAFVLYHPEAKYFNV
NT seq 3603 nt   +upstreamnt  +downstreamnt
atgaatactgccacgccccaatttaaaactgcatttctcgacgctatgaaaaatcgcgtt
ctgatcggtgatggagcaatgggtacccagctccaaggattcgatcttgacgtcgattcc
gattttctaggtctcgagggctgtaacgaaattcttaatcacactcggccagatgttgtt
tctgcaatccaccgtgcctattttgaagcgggcgccgacttggttgaaacgaatactttt
ggttgcaacctacccaatttggccgattatgacattgcagatcgatgcaaggaactcgca
ttcaaaggtgtgaaaatcgcccgagaagttgcggatgaactgggactcagtgctgatggc
acaccacgcttcgttctaggttcaatgggacctggaacgaagttgccttcgcttggacac
gcaccttatgaagcgttgaaaaatcactacaccgaagcctcacttggcatgatcgaaggc
ggcgccgatgcgattttggtcgaaactgcccaagatttgcttcaggtaaaagcagctgta
catggttgccaaactgcatttgaaacttctggcattcagcttcccattgtttgtcacgtt
acggttgaaactactggtaccatgctcctaggttccgaaatcggtgctgcacttacggca
attgagccactcaatgtggacatgattggtcttaactgtgctactggcccagacgaaatg
agcgagcaccttcgatacttgtctcgcaatgctcacattccggtttcagtcatgcccaat
gccggtttgcccatcctcggtaaaaatggtgctgaatacccactaactgaacaagagctc
gcaagcgcactgagaggatttgttgaagaatacgggctcagcatggtgggaggctgctgt
ggtacaacgcctactcatattcgtgaagtacgtaaggctgtacttggcgatagcgagcat
caaccggcacttcaggctgagagaaatcccgatgtcggagatgcagtatcgagtctctac
accagtgtgaatctcacgcaagatactggcatcaccatgattggtgagcgaacgaatgcc
aatggttctaaagctttccgcgaggccatgcttgtaggtgatcttgaaaaatgtgtggat
attgctaagcaacaaactcgcgatggcgcccacatgcttgatttatgcgttgattatgtg
ggccgtgacggcacagccgatatggcccagctggcttcactgctagcaaccagctcgaca
cttcccatcatgattgattccactgagccggatgtaatccaagtaggactcgaacattta
ggtggtcgatgcgcagtaaactctgtgaactttgaagacggcgatggcccaaattctcgc
tatcaacgcattatgcgattagtcaaacgccatggagctgctgtcgtcgctctcaccatc
gatgaagaaggtcaagctcgcactgccgaaaagaaaattgaaattgccgaacggctcata
gcggacattacgtcgacatggggattagacgaaagcgacattatcgtcgatacgcttact
ttcccgatttcaaccggccaagaagaaacgcgtcgagacggtatcgaaactatcgaggca
attcgtgagcttaaaaagcgtcatcccaaaattcacaccaccttgggcctatctaacatc
tcttttggactgaacccagctgcacgtcaggttctcaattccgtatttttgaacgagtgc
attgaagcaggactagattcggctattgcacattcgtcaaagattgttcctatgaatcgt
atcgatgaggaacagcgacgggttgctctcgacatggtgtacgaccgaaggtctgaaggc
tatgacccgcttcaaactttcatgcgcctatttgaaggtgtatctgcagcaagtgcgagc
gatgcccgcgcagaagcattagcagctatgccgttattcgagcgaatcgctcaacgtatt
attgatggcgaaaaggccggtttcgaggatgacctcgatgcaggtatgaaagaaaaagaa
ccgctccaaattatcaacgaggatctcctagaggggatgaaaaccgttggtgatctcttt
ggatcaggccaaatgcaattgcccttcgtcctgcaatctgccgagacgatgaagcatgca
gtggcttatctcgagcagttcatagaagcggatgaagatgccggcgatggtaacggaaca
attgtcatcgcaacagtgaaaggtgacgtccacgacatcggaaagaaccttgtcgacatt
attctttcaaataatggattcaatgttgtcaacattggtatcaagcaacctattgcaaac
atcctagaggctgcagaaaaacacaaagcagatgctatcggcatgtctgggctattggta
aaatctaccgtgatcatgaaggaaaaccttcaagaaatgaaccaggcacaaaaatctgac
tatccagtcattcttggtggtgcagcgcttacgcgagcctatgtagaagatgacctcacc
gaggtgtacgaaggtaatgttcactatgcaaaagatgcattcgaatcacttcgcctaatg
caagaatttatggctgaagctaggggagagcgtctcgatccacagtcgccagaagctctt
gcggccgccaagaaaaaagctgagagaaaagctcgtcgagaacgttcaaagcaaattgtc
gcgcaacgcaaagcaaaggaaattcctatcgaggttccggaacgatccgaagttgcagct
gacgtgccaattgccacacctcctttctggggaacacgaattgttaaaggcatcaattta
tccgaatacctgccgcttctcgacgaacgcgcgctgtttgtgggtcgttggggcttaaaa
gcgactcgcggtggagagggcccaagttatgaagaacttgtagaaactgaaggtcgtcca
cggctgcggtactggattgatagactcaaagctgaaaaaatacttgaccacgccgctgtc
gtgtacggatatttcccagcagtttccgaaggcgatacggtcattcttcttgaatcacca
gaccctacttctgcagaggtagcacgatttgattttcctcgacaacagcgtggaaagttc
ctttgtgtagctgacttcattagatcccgtgagcacgctatcaagaccaagacggtagac
gtattcccgctgcaattggtaactatgggacagccgattgcagactttgccaatgtcctt
tttgctgataataattaccgagactatctcgaagtacatggtgtcggtgtgcaacttaca
gaagcacttgcggagtattggcatgcccgtatccgccacgaattgtcactttccgatgga
tctcatgcaggtgacgaagattccgctgatctgcaggaattctttaatcttaaataccga
ggtgctcgttattcctttggttatggttcctgcccaaatctcgaagatcgcgaaaccttg
gtagatttgcttgactcaagtcggattggcgtagatatttcagaagagtttcaactgcac
cctgagcaatcaacagatgcatttgtgttgtatcacccagaagcaaaatacttcaatgtg
taa

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