Canis lupus familiaris (dog): 100271860 Help Entry 100271860         CDS       T01007                                  Symbol ZAP70 Name (RefSeq) tyrosine-protein kinase ZAP-70   KO K07360   tyrosine-protein kinase ZAP-70 [EC:2.7.10.2] Organism cfa  Canis lupus familiaris (dog) Pathway cfa04014   Ras signaling pathway cfa04064   NF-kappa B signaling pathway cfa04650   Natural killer cell mediated cytotoxicity cfa04658   Th1 and Th2 cell differentiation cfa04659   Th17 cell differentiation cfa04660   T cell receptor signaling pathway cfa05135   Yersinia infection cfa05235   PD-L1 expression and PD-1 checkpoint pathway in cancer cfa05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:cfa00001]  09130 Environmental Information Processing   09132 Signal transduction    04014 Ras signaling pathway     100271860 (ZAP70)    04064 NF-kappa B signaling pathway     100271860 (ZAP70)  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     100271860 (ZAP70)    04660 T cell receptor signaling pathway     100271860 (ZAP70)    04658 Th1 and Th2 cell differentiation     100271860 (ZAP70)    04659 Th17 cell differentiation     100271860 (ZAP70)  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     100271860 (ZAP70)   09171 Infectious disease: bacterial    05135 Yersinia infection     100271860 (ZAP70)   09163 Immune disease    05340 Primary immunodeficiency     100271860 (ZAP70)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:cfa01001]     100271860 (ZAP70) Enzymes [BR:cfa01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      100271860 (ZAP70) Protein kinases [BR:cfa01001]  Non-receptor tyrosine kinases   SYK family    100271860 (ZAP70) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 DUF7063 DUF7145 ABC1 SH2_1 Haspin_kinase RIO1 Kdo Motif Other DBs NCBI-GeneID:  100271860 NCBI-ProteinID:  XP_038501466 Ensembl:  ENSCAFG00000002371 VGNC:  54555 UniProt:  A0A8C0NJL6 A0A8I3P8U2 LinkDB All DBs Position 10:complement(44814558..44845740) Genome browser AA seq 617 aa AA seqDB search MPDPAAHLPFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHNVRFHHFP IERQLNGTYAIAGGKAHCGPAELCEFYSRDPDGLPCNLRKPCNRPSGLEPQPGVFDCLRD AMVRDYVRQTWKLEGEALEQAIISQAPQVEKLIATTAHERMPWYHSSLTREEAERKLYSG SQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDKAGKYCIPEGTKFDTLWQLVEYLK LKADGLIYCLKDACPNTNASSEAAAPTLPAHPSTFTQAHRRIDTLNSDGYTPEPARLASS EKAQSMPMDTSVYESPYSDPEELKDKKLFLKRENLLMADIELGCGNFGSVRQGVYRMRKK QIDVAIKVLKHSTEKTDKDEMMREAQIMHQLDNPYIVRLIGVCQAEALMLVMEMAGGGPL HKFLLGKKEEIPISNVAELLHQVSMGMKYLEEKNFVHRDLAARNVLLVNRHYAKISDFGL SKALGADDSYYTARSAGKWPLKWYAPECFNFRKFSSRSDVWSYGVTMWEAFSYGQKPYKK MKGPEVIAFIEQGKRMECPLECPPEMYTLMKDCWIYKWEDRPDFQAVEQRMRAYYYSVAS KAEDLPGCGKGVEASSV NT seq 1854 nt NT seq  +upstreamnt  +downstreamnt atgccggaccccgcggcgcacctgcccttcttctacggcagcatctcgcgcgccgaggcc gaggagcacctgaagctggcgggcatggccgacgggctcttcctgctgcgccagtgcctg cgctcgctgggcggctacgtgctctccctcgtgcacaacgtgcgcttccaccacttcccc atcgagcgccagctcaacggcacctacgccatcgccggcggcaaggcgcactgcggcccc gccgagctctgcgagttctactcgcgcgaccccgacgggctgccctgcaacctgcgcaag ccgtgcaaccggccgtccgggctcgagccgcagcccggggtcttcgactgcctgcgcgac gccatggtgcgcgactacgtgcgccagacgtggaagctggagggcgaggccctggagcag gccatcatcagccaggctccccaggtggagaagctcattgccacgacagctcatgagcgg atgccctggtaccacagcagcctgacacgcgaggaggcagagcgcaaactctattcgggc tcgcagaccgacggcaagttcctgttgaggccccggaaggagcagggcacgtatgcactg tccctgatctatgggaaaacagtgtaccactacctcatcagccaggacaaggcaggcaaa tactgtattcctgaggggaccaagtttgacacgctctggcagctggtagagtacctgaag ctaaaggcagatgggctcatctactgcctgaaggacgcttgccccaacaccaacgccagc tcagaggctgctgctcccacacttccagcccacccatccacgttcacccaagctcacagg cggattgacaccctcaactcagatggatacacccctgaaccagcacgcctagcatcctca gagaaagcacagtcaatgcccatggacacgagtgtgtatgagagcccctacagcgatcct gaggagctcaaggacaagaagctcttcctgaagcgtgagaacctcctcatggctgacata gaactcggctgtggcaactttggctcagtacgccagggcgtctaccgcatgcgcaagaag cagattgatgtggccatcaaggtgctgaagcatagcacggagaagacagacaaggatgag atgatgcgtgaggcacagatcatgcaccagctggacaacccctacattgtgcggctcatc ggtgtctgccaggccgaggccctcatgctcgtcatggagatggcgggcggtgggcccctg cacaagttcctgcttgggaagaaggaggagatccctatcagcaatgtggcagagctgctg caccaggtgtccatggggatgaagtacctggaggagaaaaactttgtgcaccgtgacctg gcggcccgcaatgtcctgctagtcaaccggcactacgccaagatcagtgactttggtctc tccaaggcactgggtgccgacgacagctattacactgcccgctcagcggggaagtggcca ctcaagtggtatgcgcccgagtgcttcaacttccgcaagttctccagccgcagtgatgtc tggagctacggggtcaccatgtgggaggccttctcctatggccagaagccctacaagaag atgaagggccctgaggtcatagccttcattgagcagggcaagaggatggagtgcccccta gagtgtccacctgaaatgtacacactcatgaaggactgttggatctacaagtgggaggac cgcccagacttccaagctgtggagcagcgcatgcgggcctactattatagcgtggcaagc aaggctgaggacctcccggggtgtggaaagggggttgaagcttcttctgtctga

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