Canis lupus familiaris (dog): 100688445
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Entry
100688445 CDS
T01007
Symbol
PINK1
Name
(RefSeq) serine/threonine-protein kinase PINK1, mitochondrial
KO
K05688
PTEN induced putative kinase 1 [EC:
2.7.11.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04137
Mitophagy - animal
cfa05012
Parkinson disease
cfa05014
Amyotrophic lateral sclerosis
cfa05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04137 Mitophagy - animal
100688445 (PINK1)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
100688445 (PINK1)
05014 Amyotrophic lateral sclerosis
100688445 (PINK1)
05022 Pathways of neurodegeneration - multiple diseases
100688445 (PINK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
100688445 (PINK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
cfa04131
]
100688445 (PINK1)
03029 Mitochondrial biogenesis [BR:
cfa03029
]
100688445 (PINK1)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
100688445 (PINK1)
Protein kinases [BR:
cfa01001
]
Serine/threonine kinases: Other
NKF2 family
100688445 (PINK1)
Membrane trafficking [BR:
cfa04131
]
Autophagy
Mitophagy
PINK1-Parkin associated proteins
100688445 (PINK1)
Mitochondrial biogenesis [BR:
cfa03029
]
Mitochondrial quality control factors
Mitophagy factors
Parkin-dependent mechanism factors
100688445 (PINK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
APH
Motif
Other DBs
NCBI-GeneID:
100688445
NCBI-ProteinID:
XP_013962588
Ensembl:
ENSCAFG00000015045
VGNC:
44567
UniProt:
A0A8I3MFF8
LinkDB
All DBs
Position
2
Genome browser
AA seq
582 aa
AA seq
DB search
MAVRQALGRGLQLGRALLLRFTAKPGPACGWGRPERPGPAAGWGRGERPGQAAGPGAERR
RLGLGLPDRYRFFRQSVAGLAARLQRQFAVRARGGAGPCGRAVFLAFGLGLGLIEEKQAE
GRRAAAACREIQAIFTQKNKLLPDPLDTRRWQGFRLEEYLIGQSIGKGCSAAVYEATMPV
LPQNREVVKSIRPLPGRGPDVDAREEEPASQAPTFPLAIKMMWNISAGSSSEAIFSTMSQ
ELVPASRVALAGEYGAVTYRKSKGGPKQLAPHPNIIRVFRAFTSSVPLLPGALVDYPDVL
PPRLHPEGLGHGRTLFLVMKNYPCTLRQYLRENTPSPRLATVMILQLLEAVDHLVQQGVA
HRDLKSDNILVELDADGCPWLVIADFGCCLADERTGLQLPFTSWYVDRGGNGCLMAPEVS
TACPGPRAVIDYSKADAWAVGTLAYEIFGLPNPFYGQGRAHLESRSYQEAQLPAMPESVP
LDARQLVRSLLQREASKRPSARVAANVLHLSLWGEHTLALKNLKLDKMIGWLLQQSAATL
LADRLTEKSCVETKMKMLFLANLEYEALCQAALLLYSWRAAP
NT seq
1749 nt
NT seq
+upstream
nt +downstream
nt
atggcggtgcgacaggcgctgggccgcggcctgcagctgggccgagcgctgctgctgcgc
ttcacggccaagcctggcccggcctgcggctgggggcggcccgagcggccgggccccgcg
gcgggctggggccgcggagaacgcccgggccaggccgcgggacccggcgcggagcggcgc
aggctggggctcgggctccccgaccgctaccgcttcttccgccagtcggtggccgggctg
gcggcgcgactccagcggcagttcgcggtgcgggcccggggtggcgcgggcccttgcggc
cgggccgtctttctggccttcgggttgggcctgggcctcatcgaggagaagcaggcggag
ggccggcgggcggcggcggcttgtcgggagatccaggcaattttcacccagaaaaacaag
ctgcttcctgaccctttggacactagacgctggcagggcttccggctggaggagtatctg
atagggcagtccattggcaagggttgcagtgctgctgtgtatgaagccaccatgcctgtg
ttgccccagaaccgggaggtggtgaagagcatcagacctcttccaggccgaggcccagat
gtcgatgcacgagaagaggagccagcttcacaggcccctacctttcccttagccatcaag
atgatgtggaatatctcggcgggctcctccagtgaagccatctttagcacaatgagccag
gaactcgtcccagctagtcgagtggccttggctggggagtacggagcggtcacttacaga
aaatccaagggtggtcccaagcagctggcccctcaccccaacatcatccgggtctttcgt
gccttcacctcttctgtaccactgctgccaggagccctggttgactaccctgatgtgctg
cccccacgtcttcaccccgaaggcctgggccacgggcggacgctcttcctcgttatgaag
aactacccctgtacgctgcgccagtacctccgcgagaacaccccaagtccccgcctcgcc
accgtgatgatcttacagctgctggaggcagtggatcatctggttcaacagggcgtcgcg
cacagagacttaaaatctgacaacattctcgtggagttggatgcagatggctgcccctgg
ctggtgatcgcagactttggctgctgcctggctgacgagcgcaccggcctgcagctgcct
ttcaccagctggtatgtggatcggggcggaaacggctgcctgatggctccagaggtgtct
actgcctgcccaggccccagggcagtgatcgactacagtaaggctgatgcctgggccgtg
ggtacgcttgcctatgaaatcttcgggctccccaatcccttttatggccagggcagggcc
caccttgaaagccgcagttaccaggaggctcagctgcccgcgatgcccgagtcagtccct
ctggatgcaagacagctggtgaggtcactgctccagcgagaggccagcaagagaccatct
gcccgagtagctgctaatgtgcttcatttaagcctctggggtgaacatactctcgccctg
aagaatctaaaactagacaagatgattggctggctcctccagcagtcagctgccactctg
ctggctgaccggctcacggagaagagctgcgtggaaaccaagatgaagatgttatttcta
gccaacctggagtacgaagcgctgtgccaggcagccctgctcctctactcctggagagca
gccccgtga
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