Canis lupus familiaris (dog): 403437
Help
Entry
403437 CDS
T01007
Symbol
BRCA1
Name
(RefSeq) breast cancer type 1 susceptibility protein homolog
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa01524
Platinum drug resistance
cfa03440
Homologous recombination
cfa03460
Fanconi anemia pathway
cfa04120
Ubiquitin mediated proteolysis
cfa04151
PI3K-Akt signaling pathway
cfa05206
MicroRNAs in cancer
cfa05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
403437 (BRCA1)
09124 Replication and repair
03440 Homologous recombination
403437 (BRCA1)
03460 Fanconi anemia pathway
403437 (BRCA1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
403437 (BRCA1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
403437 (BRCA1)
09162 Cancer: specific types
05224 Breast cancer
403437 (BRCA1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
403437 (BRCA1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
cfa01009
]
403437 (BRCA1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
cfa04121
]
403437 (BRCA1)
03036 Chromosome and associated proteins [BR:
cfa03036
]
403437 (BRCA1)
03400 DNA repair and recombination proteins [BR:
cfa03400
]
403437 (BRCA1)
Enzymes [BR:
cfa01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
403437 (BRCA1)
Protein phosphatases and associated proteins [BR:
cfa01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
403437 (BRCA1)
Ubiquitin system [BR:
cfa04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
403437 (BRCA1)
Multi subunit type E3
BRCC complex
403437 (BRCA1)
Chromosome and associated proteins [BR:
cfa03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
403437 (BRCA1)
DNA repair and recombination proteins [BR:
cfa03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
403437 (BRCA1)
BRCA1-A complex
403437 (BRCA1)
BRCA1-B complex
403437 (BRCA1)
BRCA1-C complex
403437 (BRCA1)
BRCA complex
403437 (BRCA1)
FA (Fanconi anemia) pathway
Downstream FA components
403437 (BRCA1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4
zf-C3HC4_2
zf-C3HC4_4
zf-C3HC4_3
zf-RING_UBOX
zf-RING_5
zf-RING_2
RING_XB3-XBAT31
BRCT_2
zf-Nse
zf-RING_6
zf-ANAPC11
zf-RING_10
zf-rbx1
Baculo_IE-1
Prok-RING_4
Motif
Other DBs
NCBI-GeneID:
403437
NCBI-ProteinID:
NP_001013434
Ensembl:
ENSCAFG00000014600
VGNC:
38516
UniProt:
Q95153
LinkDB
All DBs
Position
9:19422566..19486083
Genome browser
AA seq
1878 aa
AA seq
DB search
MDLSADRVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKFCMLKLLNQRKGPSQ
CPLCKNDITKRSLQESTRFSQLVEELLKIIHAFELDTGLQFADSYNFSKKENNSPEHLKE
EVSIIQSMGYRNRAKRLRQSEPENPTLETSLSVQLSNLGIVRSLRTKQQIQPQNKSVYIE
LGSDSSEDTVNKASSCSVGDDELEITSQGARAEASLNPAKKAACEFSGDITNIEHHQSSN
KDLTTTEKHATKKHPEKYQGISVSNLHVEPCGTNTHASSLQHENSSLLLTKHRMNVEKAE
ICNNSKQPGLARSQQSRWAESKETCNDRQIPSTEKKVVVNADLLCGRKELNKQKPPHSDS
PRDSQDVPWITLNSSIRKVNEWFSRSDEILTSDDSHDRGSELNTEVGGAVEVPNEVGEYS
GSSEKIDLMASDPQDAFICESERVHTKPVGGNIEDKIFGKTYRRKASLPKVSHTTEVLTI
GACAIEPQTMQTHPFMNKAEHKRRTTSSLHPEDFIKKVELGIVPKTPEKLIEGINQIKRD
GHVINITNNGPENETEGDYVQKEKNANPTESLEKESAFRTKTEPMSSRISNMELELNSSS
SKAPKKNRLRRKSSARHTCALEFVVNRNLNPPDHSELQIESCSSSEEMKKQHLDQVPVRH
NKTLQLMQDKEPAGRAKKSSKPGEQINKRLASHAFPELTLTNVSGFFANYSSSSKPQECI
NPGLRREEIEESRRMTQVSDSTRDPKELVLSGGRGLQTERSVESTSISLVLDTDYGTQDS
ISLLEADTLRKAKTVSNQQANLCATIENPKEPIHGCSKDTRNDTEGFVVPLTCKDNHTQE
TSIEMEESELDTQCLRNMFKVSKRQSFALFSYPRDPEEDCVTVCPRSGAFGKQGPKVTLE
CGQKEESQGKKESEIRHVQAVHTNAGFSAVSQKAKKPGDFAKCSIKGVSRLCLSSQFKGK
ETELLIANYHGISQNPYHIPPLSPIRSCVKTLCQENLSEEKFEQHSMSPERAVGNERVIQ
STVSTISQNNIRECASKEVGSSSVNEVVSSTNEVGSSVNEVGSSGENIQAELGRNRGPKL
NAMLRLGLMQPEVCKQSLSLSNCKHPEMKWQGQSEGAVLSVSADFSPCLISDNPEQPMGS
SRSSQVCSETPDDLLNGDKIKGKVSFAESDIKEKSAVFSKSVQSGEFSRSPSPSDHTRLA
QGYQRGTKKLESSEENMSSEEEELPCFQHLIFGKVTNMPSQSTSHNAVAAEGLSNKTEEN
LDSLKNSLSDISNQVPSAKASQEHHLSEEARCSGSLFSSQCSALEDLTVNTNTQDPFSMF
DPTSKQVRHQSENLDVLNDKELVSDDDDEREPGLEEDSPQEEQSVDSDLGEVASGYESET
SLSEDCSRLSSQSDILTTQQRDTMQDNLIKLQQEMAELEAVLEQHESQPSNSSPSLIADS
CSPEDLLNPEQNASERVLTSEKSSDSPISQNPESLSTDKFQVFLDSSTSKNGEPGMIRSS
PSQSRLLDTRWYVHSCPRSLQDTNCPSQKELTKVVSMEEQQPTESEARDLMEQSYLSRPD
LEGAPYLESGISLFSDDPESDPSSHRASELAHVSSMPTSTSALKLPQFQVEESAKSTAAV
HIASTAGYNKSEDSVGIEKPEVISSTRGVNKRISMVASGLTPKEFMLVHKFARKHHISLT
NLISEETTHVIMKTDAEFVCERTLKYFLGIAGGKWVVSYFWVTQSIKERKILDEHDFEVR
GDVVNGRNHQGPKRARESQDRESQDRKIFRGLEICCYGPFTNMPTDQLEWMVHLCGASVV
KEPSLFTLSKGTHPVVVVQPDAWTEDSGFHAIGQMCEAPVVTREWVLDSVALYQCQELDT
YLIPQIPRTAADSSQPCV
NT seq
5637 nt
NT seq
+upstream
nt +downstream
nt
atggatttatctgcggatcgtgttgaagaagtacaaaatgttcttaatgctatgcagaaa
atcttagagtgtccaatatgtctggagttgatcaaagagcctgtttctacaaagtgtgat
cacatattttgcaaattttgtatgctgaaacttctcaaccagaggaaggggccttcacag
tgtcctttgtgtaagaacgatataaccaaaaggagcctacaagaaagtacaagatttagt
caacttgttgaagagttgttgaaaatcattcatgcttttgagctggacacaggattgcag
tttgcagacagctataacttttccaaaaaggaaaataactctcctgagcatctaaaggag
gaagtttctattatccaaagtatgggctatcgaaaccgtgccaaaagacttcgacagagt
gaacctgaaaaccctaccttggaaaccagtcttagtgtccaactctctaaccttggaatt
gtgagatctctgaggacaaagcagcagatacagcctcagaataagtctgtctacattgaa
ttggggtctgattcttctgaagatacagttaataaggcaagttcttgcagtgtgggagat
gacgagttagaaatcacctctcaaggagccagggctgaagccagtttgaatcctgcaaaa
aaggctgcttgtgaattttctggggacataacaaatattgaacatcatcaatccagtaat
aaagatttgaccaccactgagaagcatgcaactaagaagcatccagaaaagtatcagggt
atttctgtttcaaacttgcatgtggagccatgtggcacaaatactcatgccagctcatta
cagcatgagaacagcagtttattactcactaaacacagaatgaatgtagaaaaggctgaa
atctgtaataacagcaaacagcctggcttagcaaggagccaacagagcagatgggctgaa
agtaaggaaacatgtaatgataggcagattcccagcacagagaaaaaggtagttgtgaat
gctgatctcctgtgtgggagaaaagaactgaataaacagaaacctccacactctgatagt
cctagagattcccaagatgttccttggataacactgaatagtagcatacggaaagttaat
gagtggttttccagaagtgacgaaatattaacttctgatgattcacatgacagaggatct
gaattgaatactgaagtaggtggtgcagtagaagttccaaatgaagtgggtgaatattct
ggttcttctgagaaaatagacttaatggccagtgatcctcaggatgctttcatatgtgaa
agtgaaagagtccacaccaagccagtaggaggtaatatcgaagataaaatatttggaaaa
acctatcggaggaaggcaagcctccctaaggtgagccacacaactgaagttctaactata
ggagcgtgtgctatagaacctcagacaatgcaaacccatcccttcatgaataaagcagag
cataaaaggagaactacatctagccttcatcctgaggattttatcaagaaagtagagtta
ggcattgttccaaagactcctgaaaagctaattgagggaatcaaccaaatcaagcgagat
ggtcatgtgataaatattacaaataatggtcctgagaatgaaacagaaggtgattatgtt
cagaaagagaaaaatgctaacccaacagaatcattggaaaaagaatctgcttttagaacc
aaaactgaaccaatgagcagcaggataagcaatatggaactggaattaaatagctccagt
tcaaaagcacctaagaagaacaggctgaggaggaagtcctctgccaggcacacttgtgcc
cttgaattcgtagtcaatagaaatctaaacccacctgatcatagtgaactacagattgaa
agttgttctagcagtgaagagatgaagaaacagcatctggaccaagtaccagtcagacac
aacaaaacacttcagctcatgcaagataaagaacctgcaggtagagctaagaaaagtagt
aagccaggagaacaaataaataagagactcgccagccatgcttttccagagctaacttta
acaaatgtatctggtttttttgctaactattcaagttctagtaagcctcaagagtgcatc
aaccctggccttcgaagagaagaaatagaagagagccgaagaatgactcaagtgtctgat
agtaccagagatcccaaagagctggtattgagtggaggaagaggtttgcaaactgagaga
tctgtagagagtaccagtatttcattggtacttgatactgattatggtacacaggacagt
atctcattactggaagctgacaccctgaggaaggcaaaaacagtatcaaatcaacaggcg
aatctgtgtgcaacaattgagaaccccaaggaacctatccatggttgttctaaggacact
agaaatgacacagagggttttgtagttccattgacgtgcaaagataaccacactcaagag
acaagcatagaaatggaagagagtgaacttgacacgcagtgcttacgcaatatgttcaag
gtttcaaagcgtcagtcatttgctctgttttcatatccaagagatccggaagaggactgt
gtaacagtctgtccccgctctggggcctttggaaaacaaggtccaaaagtcactctagaa
tgtggacagaaagaagaaagtcagggaaagaaagagtctgaaatcagacatgtgcaggca
gttcatacaaatgcaggcttttctgcagttagtcagaaagctaagaagccaggcgatttt
gccaaatgtagcataaagggagtctctcggctttgtctgtcatctcagttcaaaggcaag
gaaactgaactccttattgcaaattaccatggaatttcccaaaacccttatcatatacca
ccactttctcccatcagatcatgtgttaaaactctatgtcaggaaaacctgtcagaggaa
aagtttgagcaacattcaatgtcacccgaaagagcagtgggaaatgagagagtcattcaa
agtacagtgagcacaattagccaaaataacattagagaatgtgcttctaaagaagtcggc
tcaagcagtgttaatgaagtagtttccagtactaatgaagtaggctctagtgttaatgaa
gtaggttccagtggtgaaaacattcaagcagaactaggtagaaaccgaggacctaaatta
aatgctatgctcagattaggtcttatgcaacctgaagtctgtaagcaaagcctttcttta
agtaattgtaaacatccagaaatgaaatggcaaggacaaagtgaaggagcagttctgtct
gttagtgcagatttctctccatgtctgatttcagataacccagaacaacctatgggaagt
agtcggtcttctcaggtttgttctgagacacctgatgacctattaaatggtgacaaaata
aagggaaaagtcagctttgctgaaagtgacattaaggaaaaatctgctgtgtttagcaaa
agtgtccagagtggagagttcagcagaagccctagcccttcagaccatacacgtttggcc
cagggttaccagagagggaccaagaaattagagtcctcagaagagaacatgtctagtgag
gaggaagagcttccctgcttccaacacttaatatttggtaaagtaaccaacatgccttct
cagtctaccagtcacaatgcagttgccgcagagggtctatctaacaaaacagaggagaac
ctagactcattgaagaatagtttaagtgacatcagtaaccaggtaccgtcagcaaaggca
tcccaggaacatcaccttagtgaggaagcaagatgttctggcagcttattttcttcacag
tgcagtgctttggaagacttgactgtaaatacaaatacccaggatcctttctcgatgttt
gatcctacttccaaacaagtgaggcatcaatctgaaaatctggacgttctgaatgacaag
gaattggtttcagatgatgatgatgaaagggaacctggcctggaagaggatagtcctcaa
gaagagcagagtgtggattcagacttaggtgaagtggcatctggatatgagagtgaaacg
agcctctctgaagactgttccaggttgtcctctcagagtgatattttaaccactcagcag
agagataccatgcaagataacctgataaagctccagcaggaaatggctgaactggaagct
gtgttagagcagcatgagagccagccctctaacagctccccttcccttatagcagattct
tgttcgcctgaggatctgctgaatccggaacaaaacgcatcagaaagagtattaacttca
gagaaaagtagtgactctcctataagccagaatcccgaaagcctttctactgacaaattt
caagtatttctggatagttccaccagtaaaaatggagaaccaggaatgatacggtcttcc
ccttcacagtcccggttgttagatactagatggtatgtacacagctgcccaaggagtctt
caggacactaactgcccatctcagaaggagctcactaaggttgtcagtatggaggagcaa
caaccaactgagtcagaagcaagagatctcatggagcaatcttatttgtcaagaccagat
ctggagggagccccttacctcgaatctggaatcagccttttctctgatgaccctgagtct
gatccctcgtcacacagagcctcagagctggctcatgttagcagcatgccaacttcaacc
tctgcgttgaaattaccccaatttcaggtcgaagaatcagccaagagtacagctgctgtc
catattgctagtactgctgggtataataaaagcgaagacagtgtgggcatagaaaagcca
gaagtgatatcttcaacaagaggagtcaacaaaagaatatctatggtggcatcaggcttg
accccaaaagaatttatgcttgtgcacaagtttgccagaaaacaccacatctctttaact
aatctaatttctgaagagacaactcatgtcattatgaaaacagatgctgagtttgtgtgc
gaacgaacactgaaatattttctgggtattgcaggaggaaaatgggtagttagctatttc
tgggtaacccagtctattaaagaaagaaagatactagatgagcatgattttgaagtcaga
ggagatgttgtgaatggaagaaatcaccagggtccgaagcgagcaagagaatcccaggac
agagaatcccaagacagaaagatcttcaggggcctagaaatctgttgctatggacccttt
accaacatgcccacagatcaattagagtggatggtgcacctctgtggggcttctgtggtg
aaggagccttcgttattcaccctcagcaagggcactcatccagtggtagtcgtgcagccg
gacgcctggacagaggacagtggcttccatgcgattgggcagatgtgtgaggcacctgtg
gtgacccgagagtgggtactggacagtgtagccctctaccagtgccaggagctggacacc
tacctgatcccgcagattcccagaactgctgcagactccagccagccatgcgtgtaa
DBGET
integrated database retrieval system
