Canis lupus familiaris (dog): 403494
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Entry
403494 CDS
T01007
Symbol
RET
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04010
MAPK signaling pathway
cfa04020
Calcium signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa05200
Pathways in cancer
cfa05216
Thyroid cancer
cfa05223
Non-small cell lung cancer
cfa05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
403494 (RET)
04020 Calcium signaling pathway
403494 (RET)
04151 PI3K-Akt signaling pathway
403494 (RET)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
403494 (RET)
05230 Central carbon metabolism in cancer
403494 (RET)
09162 Cancer: specific types
05216 Thyroid cancer
403494 (RET)
05223 Non-small cell lung cancer
403494 (RET)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
403494 (RET)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
403494 (RET)
Protein kinases [BR:
cfa01001
]
Receptor tyrosine kinases (RTK)
RET family
403494 (RET)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD4
RET_CLD1
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
403494
NCBI-ProteinID:
NP_001184028
Ensembl:
ENSCAFG00000007076
VGNC:
45481
LinkDB
All DBs
Position
28:complement(4180472..4211554)
Genome browser
AA seq
1108 aa
AA seq
DB search
MAASRIIKGWFVPFCQAPLGLYFSRDAYWEKLYVDQPSGMPLLYVHALRDIPEEVPSFRL
GQHLYGIAYRARLHENDWIRIEEDTGLLYLNRSLDHSTWEKLSIRNGGFPVLTIYVQVFL
SSASLREGECQWPGCARVYFSFINTSFPACGSLKPRELCFPETGVSFRIRENRPPGTFHQ
FRLLPMQFLCPNISVSYKLLEGENLPFRCAPDSLEVSTRWALDRELREKYELVAACTVRV
GARKEEVVMVPFPVTVYDEDDSAPTFLGGFDTASAVVEFKRKEGTVVATIHVFDADVVPA
SGELLRRYTSTLLPGDAWALQTFRVEHSPNETLVQANGSFVRATVHDYRLVLNRSLPISE
SRSLQLAVLVNDSDFQGPGEGILLLHFNVTVLPVSLHLPSAYTFTVSRRARRFAQIGKVC
VENCQEFSGIHVQYKLQLSSTNCSVLGVVTSAEDTTGTLYVNDTEALQRLDCSQLQYTVV
AADRPTRRQTQAPLVVTVEGTYVAEEPGCPLSCAVSKRRPECEECGGLGSLTGKCEWRQG
DGKGITRNFSTCSPNVKTCPDGHCDAVESRNVNICPQDCLRGSIIGGHEPGDRWGIKAGF
GICNCFPEEKKCFCEPEDSQDPLCDELCRTVIAAAVLFSFIVSMLLSTFCIHRYHKNAHK
PPIASAEMTFRRPAQAFPVSYSSSGARRPSLDSMENQVSVDAFKIPEDPKWEFPRKNLVL
GKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSEFNLLKQVNHPH
VIKLYGACSQDGPLFLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRSSSYLDNPEERAL
TMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGLSRDVYEEDSYV
KRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKT
GYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKNRDYLDLAASTPSDS
LLYDDGLSEEETPLVDCNNAPLPRTLPSTWIENKLYGMSDPNWPEESPVPLTRADGTNSV
CPRYANDSVYANWMVSPSAAQLMDAFDS
NT seq
3327 nt
NT seq
+upstream
nt +downstream
nt
atggcagcatctcggatcattaagggttggttcgtgcccttctgccaggctccactggga
ctctacttctccagggatgcttattgggagaagctgtatgtggaccagccatctggcatg
cccctgctctatgtccatgccctgcgggacatccccgaggaggtgcctagcttccgccta
ggccagcacctttacggcatcgcctaccgtgcaaggctgcatgagaacgactggatccgc
atcgaggaggacacaggccttctctaccttaaccggagcctggatcacagcacctgggag
aagctcagcatccgcaatggcggcttccctgtgctcaccatctacgtccaggtcttcctg
tcatctgcatccctgcgtgagggcgagtgccagtggccaggctgtgcccgtgtgtacttc
tccttcattaacacctccttcccagcttgtggttccctcaaaccccgggagctctgcttc
cctgagactggtgtctccttccgcattcgagagaacaggcctcccggcaccttccaccaa
ttccgtctgctgcccatgcagttcctctgccccaacatcagcgtgtcctacaagctccta
gaaggtgagaatctgcccttccgttgcgccccggacagcctggaggtgagcacacgctgg
gccctggaccgtgagctgcgggagaagtatgagctggtggccgcgtgcaccgtgcgcgtc
ggtgcgcgtaaagaggaggtggtgatggtgcccttccccgtgaccgtgtatgacgaggac
gactcggcgcccaccttcctcgggggcttcgacactgccagcgccgtggtggagttcaag
aggaaggagggcactgtggtggccacaatacatgtctttgacgcggacgtggtaccagca
tctggggagctcctgaggcgatacacaagtacactactccctggggatgcctgggccctc
cagacatttcgtgtggaacactcacccaacgagaccttggtccaggccaacggcagcttt
gtgcgggcaactgtgcatgactacaggctggttctcaaccggagcctccccatctcggag
agccgctccctgcagctggccgttctggtcaatgactcggacttccagggtcccggggag
ggcatcctcttgctccacttcaacgtgacggtgctgcctgtcagcctgcacttacccagc
gcctacaccttcactgtgagcagacgggcccgccgctttgcccagattgggaaagtctgt
gtggaaaactgccaggagttcagtggcatccacgtgcagtacaagctgcagctctccagc
accaactgtagcgtcctgggggtggtcacgtcagccgaggacaccacagggaccctgtac
gtgaatgacacggaagccctgcagcggctcgattgttctcaactccagtacacagtggtg
gctgccgaccggccaacccgcaggcagacccaggccccgctggtcgtcaccgtggagggg
acatatgtggctgaggagccaggctgccccctgtcctgtgcagtcagcaagagacggcct
gagtgtgaagagtgcggcggcctgggctctctgacgggcaagtgcgagtggagacaggga
gatggcaaagggatcaccagaaacttctccacctgctcccccaatgtcaagacctgccct
gatggccactgtgatgctgtagagagcaggaatgtcaacatctgcccccaggactgcctc
cgtggcagcatcatcggtgggcatgagccaggggaccgctgggggataaaagctggcttc
ggaatctgcaactgttttcctgaagagaagaagtgcttctgcgagcctgaagacagccag
gacccactgtgtgatgagctctgccgcacggtgattgcagcggctgtgctcttctccttc
atcgtctccatgctgctctccaccttctgcatccaccgctaccacaagaatgcccacaag
ccgcccatcgcctctgccgaaatgaccttccgccggcccgcccaggccttcccagtcagc
tactcctcatcaggcgcccgccggccctcactggactccatggagaaccaggtctctgtg
gatgccttcaaaatcccggaggatcctaagtgggaattccctcggaagaacttagttctt
ggaaaaactctgggagaaggtgaatttggaaaagtggttaaggcaacagctttccggcta
aaaggcaaagcaggatacacgaccgttgccgtgaagatgctgaaagagaatgcttcccca
agcgagctgcgggatctgctatcagaattcaatctcctgaagcaggtcaaccacccgcat
gtcatcaagctgtacggagcctgcagccaggatgggccactcttcctcattgtggagtat
gccaagtatggctcactgcggggcttcctccgagaaagccgcaaggcgggtccaggctac
gtgggcagtggaggcagccgaagctccagctacctggacaaccccgaggagcgggcgctg
accatgggcgacctcatctccttcgcctggcagatctctcgggggatgcggtacctggca
gagatgaagcttgtccatcgggacttggccgccagaaacgtcctggtggctgaggggcgg
aagatgaagatttcagattttggcctctcccgagatgtttatgaggaggattcctacgtg
aagaggagcaagggtcggattccagtcaagtggatggcaattgaatctcttttcgatcat
atctataccacccaaagtgatgtgtggtccttcggtgtcctgctgtgggagattgtgact
ctggggggcaacccctaccctgggattcctccagagcggctcttcaaccttctgaagaca
ggctaccggatggagaggcctgacaactgcagcgaggagatgtatggtctaatgctgcag
tgttggaagcaggaaccagacaagaggccagtgtttgctgacatcagcaaagacctagag
aagatgatggttaagaacagagactacttggacctggcggcgtccaccccatctgactcc
ctgctttatgacgatggcctctcggaggaggagacacctctggtggactgtaataatgct
cccctccctcgaacccttccctccacgtggattgaaaacaaactctatggcatgtcagac
ccgaactggcctgaagagagtcctgtaccactcacgagagctgatggcactaactctgtg
tgtccaagatatgcaaatgatagtgtatatgctaactggatggtttcaccctcagcggca
caattaatggacgcatttgatagttaa
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