Canis lupus familiaris (dog): 403693 Help Entry 403693            CDS       T01007                                  Symbol MDM2 Name (RefSeq) E3 ubiquitin-protein ligase Mdm2   KO K06643   E3 ubiquitin-protein ligase Mdm2 [EC:2.3.2.27] Organism cfa  Canis lupus familiaris (dog) Pathway cfa01522   Endocrine resistance cfa01524   Platinum drug resistance cfa04068   FoxO signaling pathway cfa04110   Cell cycle cfa04115   p53 signaling pathway cfa04120   Ubiquitin mediated proteolysis cfa04144   Endocytosis cfa04151   PI3K-Akt signaling pathway cfa04218   Cellular senescence cfa04625   C-type lectin receptor signaling pathway cfa04919   Thyroid hormone signaling pathway cfa05163   Human cytomegalovirus infection cfa05165   Human papillomavirus infection cfa05169   Epstein-Barr virus infection cfa05200   Pathways in cancer cfa05202   Transcriptional misregulation in cancer cfa05203   Viral carcinogenesis cfa05205   Proteoglycans in cancer cfa05206   MicroRNAs in cancer cfa05214   Glioma cfa05215   Prostate cancer cfa05218   Melanoma cfa05219   Bladder cancer cfa05220   Chronic myeloid leukemia Brite KEGG Orthology (KO) [BR:cfa00001]  09120 Genetic Information Processing   09123 Folding, sorting and degradation    04120 Ubiquitin mediated proteolysis     403693 (MDM2)  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     403693 (MDM2)    04151 PI3K-Akt signaling pathway     403693 (MDM2)  09140 Cellular Processes   09141 Transport and catabolism    04144 Endocytosis     403693 (MDM2)   09143 Cell growth and death    04110 Cell cycle     403693 (MDM2)    04115 p53 signaling pathway     403693 (MDM2)    04218 Cellular senescence     403693 (MDM2)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     403693 (MDM2)   09152 Endocrine system    04919 Thyroid hormone signaling pathway     403693 (MDM2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     403693 (MDM2)    05202 Transcriptional misregulation in cancer     403693 (MDM2)    05206 MicroRNAs in cancer     403693 (MDM2)    05205 Proteoglycans in cancer     403693 (MDM2)    05203 Viral carcinogenesis     403693 (MDM2)   09162 Cancer: specific types    05214 Glioma     403693 (MDM2)    05220 Chronic myeloid leukemia     403693 (MDM2)    05218 Melanoma     403693 (MDM2)    05219 Bladder cancer     403693 (MDM2)    05215 Prostate cancer     403693 (MDM2)   09172 Infectious disease: viral    05163 Human cytomegalovirus infection     403693 (MDM2)    05169 Epstein-Barr virus infection     403693 (MDM2)    05165 Human papillomavirus infection     403693 (MDM2)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     403693 (MDM2)    01522 Endocrine resistance     403693 (MDM2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:cfa04131]     403693 (MDM2)    04121 Ubiquitin system [BR:cfa04121]     403693 (MDM2) Enzymes [BR:cfa01000]  2. Transferases   2.3  Acyltransferases    2.3.2  Aminoacyltransferases     2.3.2.27  RING-type E3 ubiquitin transferase      403693 (MDM2) Membrane trafficking [BR:cfa04131]  Endocytosis   Clathrin-mediated endocytosis    Ubiquitin E3 ligases     403693 (MDM2) Ubiquitin system [BR:cfa04121]  Ubiquitin ligases (E3)   Single Ring-finger type E3    MDM2/MDM4 proteins     403693 (MDM2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  zf-C3HC4_3 Zn_ribbon_RanBP SWIB zf-RING_2 zf-FPG_IleRS Motif Other DBs NCBI-GeneID:  403693 NCBI-ProteinID:  NP_001003103 Ensembl:  ENSCAFG00000000418 VGNC:  43106 UniProt:  P56950 LinkDB All DBs Position 10:10869091..10894634 Genome browser AA seq 487 aa AA seqDB search MCNTNMSVSTDGAVSTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVIFYLGQY IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQHEPSDSGT SVSENSCHREGGSDQKDPVQELQEEKPSSSDLISRPSTSSRRRTISETEEHADDLPGERQ RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDHHS VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYRVTVYQAGESDTDSFEEDPEISLA DYWKCTSCNEMNPPLPPHCNRCWALRENWLPEDKGKIPEKATPENSTQVEEGFDVPDCKK AAASDSRESCAEEIDDKITQASHSQESEDYSQPSTSNSIIYSSQEDVKEFEREETQDKEE IVESSFPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQM IVLTYFP NT seq 1464 nt NT seq  +upstreamnt  +downstreamnt atgtgcaataccaacatgtctgtgtctactgatggtgctgtaagcacctcacagattcca gcttcggagcaggagaccctggttagaccaaagccattgcttttgaagttgttgaagtct gtaggtgcacaaaaagacacttatactatgaaagaggtgatattttatcttggccagtat attatgactaaacgattgtatgatgagaagcaacagcatattgtgtattgttccaatgat cttctaggagatttgtttggagtgccaagcttctctgtgaaagagcacaggaaaatatat acaatgatctacagaaacttggtagtagtcaatcagcatgaaccatcagattcaggcaca tctgtgagtgaaaatagctgtcaccgtgaaggtgggagtgatcaaaaggaccctgtgcaa gagttgcaggaagagaaaccttcatcttcagatttgatttctagaccatctacctcatct agaaggagaacaattagtgagacagaagaacatgcagatgatttacctggtgaacggcag agaaagcgccacaaatctgatagtatttccctttcctttgatgaaagccttgctctgtgt gtaataagggagatatgttgtgaaagaagcagtagcagtgagtcaacagggacgccatca aatccggatcttgatgctggtgtaagtgaacattcaggtgattggttggatcaccattca gtttcagatcaattcagtgtagaatttgaagttgagtctcttgattcagaagattatagc cttagtgaagaaggacaagaactctcagatgaagatgatgaggtgtatcgagtaactgtg tatcaggcaggggagagtgatacagattcatttgaagaagatcctgaaatttccttagct gactattggaagtgtacctcatgcaatgaaatgaatcctcctcttccacctcattgcaat agatgttgggcccttcgtgagaattggcttcctgaagataaagggaaaatccctgagaaa gccacaccagaaaactcaacacaagtagaagagggctttgatgtccctgattgtaaaaaa gctgcagccagtgattccagagaatcatgtgctgaggaaattgatgataaaatcacacaa gcctcccactcccaagaaagtgaggactattctcagccatcaacttctaacagcatcatt tatagcagccaagaagatgtcaaagaatttgagagagaagaaacacaagacaaagaagaa attgtggaatctagttttccccttaatgccattgaaccttgtgtgatttgccaaggtcga cctaaaaacggttgcattgttcatggcaaaacaggacatcttatggcatgcttcacgtgt gcaaagaagctaaagaaaaggaataagccctgtccagtatgtagacaaccaattcaaatg attgtgctaacttatttcccctag

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