Canis lupus familiaris (dog): 403716
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Entry
403716 CDS
T01007
Symbol
SRD5A1
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 1
KO
K12343
3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:
1.3.1.22
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00140
Steroid hormone biosynthesis
cfa01100
Metabolic pathways
Module
cfa_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
cfa_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
403716 (SRD5A1)
Enzymes [BR:
cfa01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
403716 (SRD5A1)
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GFIT
Motif
Pfam:
Steroid_dh
DUF1295
GREB1_C
PEMT
Motif
Other DBs
NCBI-GeneID:
403716
NCBI-ProteinID:
NP_001274029
Ensembl:
ENSCAFG00000010323
VGNC:
46793
UniProt:
A0A8P0P128
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Position
34:complement(11627110..11653073)
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AA seq
255 aa
AA seq
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MEPAEVSRLHALAYLQCALGFLGSLLLRQAASSYGRYASPGAAFGVPARAAWALQELPSL
AVPLWVCARTAAERLRRAPNRILLAMFLLHYAQRSLIFPFLIRGGKPMPLYTCVLAFTFC
VYNGYLQSRYLSQYAVYADDWVTDPRFLVGFCLWLIGMLINIHSDHILRNLRKPGETGYK
IPRGGLFEYVTAANYFGEVVEWCGYGLASWSIQGGAFALFTFCILLTRAQQHHRWYLEKF
EDYPKFRKIIIPFLF
NT seq
768 nt
NT seq
+upstream
nt +downstream
nt
atggagccggccgaggtctcccggctgcacgcgctcgcctacctgcagtgcgcgctgggc
ttcctgggctccctgctgctccgccaggcggcctcgtcctacgggcgctacgcgtcgccg
ggcgccgccttcggggtgccggcgcgggccgcctgggcgctgcaggagctgccctcgctg
gccgtgccgctgtgggtgtgcgcccgcaccgccgccgagcgcctccgccgcgcgcccaac
cgcatcctcctggccatgttcctcctgcactacgcgcaacggtccttgattttcccattt
ctgattcgaggaggaaagccgatgcccctgtacacgtgtgtattggcgttcacgttctgt
gtctacaatggctacttgcagagcagatacttgagccagtacgccgtgtatgctgacgac
tgggtcacagatccccggtttctagtgggtttctgcttgtggttaatcggtatgctgata
aacatccattcagaccatattctgaggaatctccgaaaaccgggggagactggatataag
attcccaggggaggcttatttgaatatgtaacagcagccaactactttggggaggtggtt
gagtggtgtggctacggcctggccagctggtccattcaaggcggggccttcgctctcttc
accttctgcattttactcacccgggcacagcagcatcaccggtggtaccttgagaaattt
gaagattacccaaaattcagaaaaattataatcccatttttgttttaa
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