Canis lupus familiaris (dog): 403727
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Entry
403727 CDS
T01007
Symbol
FLT1
Name
(RefSeq) vascular endothelial growth factor receptor 1 isoform X1
KO
K05096
FMS-like tyrosine kinase 1 [EC:
2.7.10.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04010
MAPK signaling pathway
cfa04014
Ras signaling pathway
cfa04015
Rap1 signaling pathway
cfa04020
Calcium signaling pathway
cfa04066
HIF-1 signaling pathway
cfa04151
PI3K-Akt signaling pathway
cfa04510
Focal adhesion
cfa05202
Transcriptional misregulation in cancer
cfa05323
Rheumatoid arthritis
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
403727 (FLT1)
04014 Ras signaling pathway
403727 (FLT1)
04015 Rap1 signaling pathway
403727 (FLT1)
04066 HIF-1 signaling pathway
403727 (FLT1)
04020 Calcium signaling pathway
403727 (FLT1)
04151 PI3K-Akt signaling pathway
403727 (FLT1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
403727 (FLT1)
09160 Human Diseases
09161 Cancer: overview
05202 Transcriptional misregulation in cancer
403727 (FLT1)
09163 Immune disease
05323 Rheumatoid arthritis
403727 (FLT1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
403727 (FLT1)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
403727 (FLT1)
Protein kinases [BR:
cfa01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
403727 (FLT1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Ig_3
I-set
Pkinase
ig
VEGFR-1-like_Ig-like
Ig_2
Ig_VEGFR-1-like_5th
V-set
VEGFR-2_TMD
VEGFR1-3_N_Ig-like
C1-set
Ig_4
Ig_5
Haspin_kinase
Herpes_gE
Motif
Other DBs
NCBI-GeneID:
403727
NCBI-ProteinID:
XP_005635561
Ensembl:
ENSCAFG00000006701
VGNC:
40907
LinkDB
All DBs
Position
25:11295043..11473288
Genome browser
AA seq
1314 aa
AA seq
DB search
MVSCRDTGVLLCALLGGLLLTGSSSGSKLKGPELSLKGTQHVMQAGQTLYLKCRGEAAHS
WSLPETVRKESKRLSITKSACGRNGKQFCSTLTLNMAQANHTGFYSCKYLSIPASKKKKT
ESTIYIFINDTGRPFLEMHSEIPEIIYMTEGRQIVIPCRVTSPNITVTLKKFPLDTLIPD
GKRITWDSRKGFIIANATYREIGLLTCETTVNGHLYKTNYLTYRQTNTIRDVQINTPSPV
KLLRGHTLTLNCTATTALNTRVQMNWSYPGEKNKRASIRQRIGQRSSHANVFYSVLIIDK
VQNKDKGLYTCHVKSGPSFKSVNTSVHIYDKAFITVKHRKEHVLETIAGKRSYRLSVKVK
AFPSPEVLWLKDGFPVTEKSARYLVHGYSLIIKDVAAEDAGDYMILLAIKQSSVFKNLTT
TLIVNVKPQIYEKAVSSFPDPTLYPLGSRQILTCTIYGIPQPTVRWFWRPCNHNHSKARY
DFCSSKEESLIVELDSNIGNRIESITQRTAIIEGKNKTASTLVVADARISGIYSCMASNK
IGTVERNISFYVTDVPNGFHINLEKMPTEGEDLKLSCTVNKFLYRDITWILLRTVKNRTM
HHSISKQKMATTKEYSITLNVTIKNVSLEDSGTYACRARNIYTGEEILQKKEVTIRDQEA
PHLLRNLSDHTVAISSSTTLDCPATGVPEPEITWFKNNHKIQQEPGIILGPGSSTLFIER
VTEEDEGVYHCKATNQKGSVESSAYLTVQGTSDKSNLELITLTCTCVAATLFWLLLTLFI
RKLKRSSSEIKTDYLSIIMDPDEVPLDEQCERLPYDASKWEFARERLKLGKSLGRGAFGK
VVQASAFGIKKSPTCRTVAVKMLKEGATASEYKALMTELKILTHIGHHLNVVNLLGACTK
QGGPLMVIVEYCKYGNLSNYLKSKRDLFFLNKDAALHMEPKKEKMEPDPEQDKKQRLDSV
TSSESFASSGFQEDKSLSDVEEEEDSDDFYKQPITMEDLISYSFQVARGMEFLSSRKCIH
RDLAARNILLSENNVVKICDFGLARDIYKNPDYVRKGDTRLPLKWMAPESIFDKIYSTKS
DVWSYGVLLWEIFSLGGSPYPGVQMDEDFCSRLKEGMRMRAPEYATPEIYQIMLDCWHKD
PKERPRFAELVEKLGDLLQANVQQDGKDYIPLNAILTGNSGFTYSSPAFSDDFFKEDISA
PKFNSGSSDNVRYVNAFNFMSLERIKTFEELSPNTTSIFDDYQVDSSTLLASPLLKRFTW
AESKPKASLKIECGHINRGRRRFTYDNSELEKKISCCSPPPDYNSVVLYSTPPV
NT seq
3945 nt
NT seq
+upstream
nt +downstream
nt
atggtcagctgccgggacaccggggtcctgctgtgcgcgctgcttggcggcctgctgctc
acaggatctagttcaggctcaaaattaaaaggtcctgaactgagtttaaaaggcacccag
cacgtcatgcaagcaggccagacactgtatctcaaatgtagaggggaagcagcccattca
tggtctttgcctgaaacagtgagaaaggaaagcaaaaggctgagcattactaaatctgcc
tgtggaaggaatggcaaacagttctgcagtactttgaccttgaacatggctcaggcaaac
cacactggcttctatagctgcaaatatctatctatacctgcttcaaagaagaagaaaaca
gaatctacaatctatatatttattaatgatacaggtagacctttcttagagatgcacagt
gaaatacccgaaattatatatatgactgaaggaaggcagatcgtcatcccctgccgggtc
acgtcacctaacatcactgttactttaaaaaagtttccacttgataccctgatccctgat
gggaagcgaataacctgggacagtaggaagggttttataatagcaaatgcaacatacaga
gaaatagggcttctcacctgtgaaacaacagtcaacggccatttgtacaagacaaactat
cttacctatcgacaaaccaatacaatcagagatgtccagataaataccccaagcccagtc
aagttacttagaggtcacactcttaccctcaactgtactgctaccactgccttgaacaca
agagttcagatgaactggagttaccctggtgaaaaaaataagagagcttctataaggcaa
cgaattggccaacgcagttcccatgccaatgtgttctacagcgttcttattattgacaaa
gtgcagaacaaagacaaaggactttacacttgtcacgtgaagagtggtccatcattcaaa
tctgtcaacacctcagtccatatatatgataaggcattcatcactgtgaagcatcgaaaa
gagcatgtgcttgaaaccatagctggcaagcggtcctacaggctgtccgtgaaagtgaag
gcattcccctcaccagaagttctgtggctaaaagatgggttccccgtgactgagaaatct
gctcgctatttggttcatggctactcgttaatcatcaaagatgtggctgcagaagatgca
ggggactacatgatcttgctggccataaagcagtcgagtgtgtttaaaaacctcaccacc
actttaattgtaaatgtgaaaccccagatttatgaaaaggccgtgtcatcctttccagac
cctactctctatcccctgggcagcagacaaatcctgacctgtaccatttacggtatccct
caacctacagtcagatggttctggcgtccctgtaaccataatcattccaaagcaaggtat
gacttttgctccagcaaggaagagtctctaatcgtggagctggacagcaatataggaaac
aggattgagagcatcactcagcgcacggcaataatagaaggaaagaataagacggctagc
accttggttgtggctgacgctagaatttctggaatctacagttgcatggcttccaataaa
atagggactgtggaaagaaacataagcttttatgtcacagatgtgccaaatggatttcac
attaacttggaaaaaatgcctacggagggtgaggacctgaaactgtcttgcacagttaac
aagttcttatacagagacattacttggattttgctgcggacagttaaaaaccgaacaatg
caccacagcatcagcaagcaaaaaatggccaccactaaagagtactccatcaccctcaat
gtcaccatcaagaatgtttccctggaagactcaggcacctatgcctgcagagccaggaac
atatacacaggggaagaaatccttcagaagaaagaagttacaattagagatcaggaagcc
ccacacctgctgcgaaacctcagtgatcacacggtggccatcagcagctcgaccacatta
gactgtcctgctactggtgtcccagagcccgagataacctggtttaaaaacaaccacaaa
atacagcaagaacccggaattattttaggaccaggaagcagcacactgtttattgaaaga
gtcacagaagaggatgaaggtgtctatcactgcaaagccaccaaccagaagggatccgtg
gaaagctcggcatacctcactgttcaaggaacctcggacaagtctaatctggagctaatt
actctgacgtgtacctgtgtggctgcaaccctcttctggctcctattaacgctctttatc
cgaaaactgaaaaggtcttcttctgaaataaagactgactacttatcaattataatggat
ccagacgaagttcccctggacgagcaatgtgagcggctcccttatgatgccagcaagtgg
gagtttgcccgggagagacttaaactgggcaagtcacttggaagaggggcttttggaaaa
gtggttcaagcttctgcatttggcattaagaaatcacctacatgccggactgtggctgta
aaaatgctgaaagagggggccacagccagcgaatacaaagctctgatgactgagctcaag
atcttgacccacattggccaccatctgaatgtagtcaacctgctaggagcctgtaccaag
caaggagggcctctgatggtgatcgttgaatattgcaaatacggaaatctgtccaactac
ctcaagagcaaacgagacttattctttctcaacaaggatgcagcattacacatggagcct
aagaaagaaaaaatggagccagatccggagcaagacaagaaacaaagactagatagtgtc
accagcagtgagagcttcgcaagctccgggtttcaggaagataaaagtctgagtgatgtt
gaggaagaggaggattccgatgatttctacaagcagcccatcactatggaagatctgatt
tcttacagttttcaagtggccagaggcatggagtttttgtcttccagaaagtgcatccat
cgggacctggcagcgagaaatattcttttatctgagaacaatgtggtgaagatctgcgat
tttggccttgcccgggacatttataaaaaccccgattacgtgagaaaaggagatacacgc
cttcctctgaagtggatggctcctgaatctatcttcgacaaaatctacagcaccaagagt
gacgtgtggtcttacggagtactgctgtgggaaatcttctccctaggtgggtctccatac
ccaggcgtgcaaatggacgaggacttctgcagccgcctgaaggaaggcatgaggatgagg
gccccggaatacgccactcctgaaatctatcagatcatgttggactgctggcacaaagac
cctaaagaaaggccaagatttgcagaacttgtggaaaaactaggtgatttgcttcaagca
aatgtacaacaggatggaaaagactatatcccactaaatgccatactgacaggaaatagt
ggatttacatactcatctcctgccttctctgatgacttcttcaaggaagatatctcagct
ccaaagtttaattcaggaagttctgataatgtcagatatgtaaatgctttcaatttcatg
agcctggagagaatcaaaacctttgaagaactttcaccaaacaccacctctatttttgat
gactaccaagtggacagtagcactctgctggcttcccccttgctgaagcgcttcacctgg
gctgagagcaaacccaaggcctccctgaagattgagtgtgggcacatcaacagaggcagg
cgcagatttacatatgacaactcagagctggaaaagaagatttcgtgctgctcgcctccc
ccagactacaactcggtggtcttatactccaccccgcctgtctaa
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integrated database retrieval system
