KEGG   Canis lupus familiaris (dog): 403869
Entry
403869            CDS       T01007                                 
Symbol
TP53
Name
(RefSeq) cellular tumor antigen p53
  KO
K04451  tumor protein p53
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa01522  Endocrine resistance
cfa01524  Platinum drug resistance
cfa04010  MAPK signaling pathway
cfa04071  Sphingolipid signaling pathway
cfa04110  Cell cycle
cfa04115  p53 signaling pathway
cfa04137  Mitophagy - animal
cfa04151  PI3K-Akt signaling pathway
cfa04210  Apoptosis
cfa04211  Longevity regulating pathway
cfa04216  Ferroptosis
cfa04218  Cellular senescence
cfa04310  Wnt signaling pathway
cfa04722  Neurotrophin signaling pathway
cfa04919  Thyroid hormone signaling pathway
cfa05012  Parkinson disease
cfa05014  Amyotrophic lateral sclerosis
cfa05016  Huntington disease
cfa05160  Hepatitis C
cfa05161  Hepatitis B
cfa05162  Measles
cfa05163  Human cytomegalovirus infection
cfa05165  Human papillomavirus infection
cfa05166  Human T-cell leukemia virus 1 infection
cfa05167  Kaposi sarcoma-associated herpesvirus infection
cfa05168  Herpes simplex virus 1 infection
cfa05169  Epstein-Barr virus infection
cfa05200  Pathways in cancer
cfa05202  Transcriptional misregulation in cancer
cfa05203  Viral carcinogenesis
cfa05205  Proteoglycans in cancer
cfa05206  MicroRNAs in cancer
cfa05210  Colorectal cancer
cfa05212  Pancreatic cancer
cfa05213  Endometrial cancer
cfa05214  Glioma
cfa05215  Prostate cancer
cfa05216  Thyroid cancer
cfa05217  Basal cell carcinoma
cfa05218  Melanoma
cfa05219  Bladder cancer
cfa05220  Chronic myeloid leukemia
cfa05222  Small cell lung cancer
cfa05223  Non-small cell lung cancer
cfa05224  Breast cancer
cfa05225  Hepatocellular carcinoma
cfa05226  Gastric cancer
cfa05230  Central carbon metabolism in cancer
cfa05417  Lipid and atherosclerosis
cfa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    403869 (TP53)
   04310 Wnt signaling pathway
    403869 (TP53)
   04071 Sphingolipid signaling pathway
    403869 (TP53)
   04151 PI3K-Akt signaling pathway
    403869 (TP53)
 09140 Cellular Processes
  09141 Transport and catabolism
   04137 Mitophagy - animal
    403869 (TP53)
  09143 Cell growth and death
   04110 Cell cycle
    403869 (TP53)
   04210 Apoptosis
    403869 (TP53)
   04216 Ferroptosis
    403869 (TP53)
   04115 p53 signaling pathway
    403869 (TP53)
   04218 Cellular senescence
    403869 (TP53)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    403869 (TP53)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    403869 (TP53)
  09149 Aging
   04211 Longevity regulating pathway
    403869 (TP53)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    403869 (TP53)
   05202 Transcriptional misregulation in cancer
    403869 (TP53)
   05206 MicroRNAs in cancer
    403869 (TP53)
   05205 Proteoglycans in cancer
    403869 (TP53)
   05203 Viral carcinogenesis
    403869 (TP53)
   05230 Central carbon metabolism in cancer
    403869 (TP53)
  09162 Cancer: specific types
   05210 Colorectal cancer
    403869 (TP53)
   05212 Pancreatic cancer
    403869 (TP53)
   05225 Hepatocellular carcinoma
    403869 (TP53)
   05226 Gastric cancer
    403869 (TP53)
   05214 Glioma
    403869 (TP53)
   05216 Thyroid cancer
    403869 (TP53)
   05220 Chronic myeloid leukemia
    403869 (TP53)
   05217 Basal cell carcinoma
    403869 (TP53)
   05218 Melanoma
    403869 (TP53)
   05219 Bladder cancer
    403869 (TP53)
   05215 Prostate cancer
    403869 (TP53)
   05213 Endometrial cancer
    403869 (TP53)
   05224 Breast cancer
    403869 (TP53)
   05222 Small cell lung cancer
    403869 (TP53)
   05223 Non-small cell lung cancer
    403869 (TP53)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    403869 (TP53)
   05161 Hepatitis B
    403869 (TP53)
   05160 Hepatitis C
    403869 (TP53)
   05162 Measles
    403869 (TP53)
   05168 Herpes simplex virus 1 infection
    403869 (TP53)
   05163 Human cytomegalovirus infection
    403869 (TP53)
   05167 Kaposi sarcoma-associated herpesvirus infection
    403869 (TP53)
   05169 Epstein-Barr virus infection
    403869 (TP53)
   05165 Human papillomavirus infection
    403869 (TP53)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    403869 (TP53)
   05014 Amyotrophic lateral sclerosis
    403869 (TP53)
   05016 Huntington disease
    403869 (TP53)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    403869 (TP53)
   05418 Fluid shear stress and atherosclerosis
    403869 (TP53)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    403869 (TP53)
   01522 Endocrine resistance
    403869 (TP53)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:cfa03000]
    403869 (TP53)
   03036 Chromosome and associated proteins [BR:cfa03036]
    403869 (TP53)
   03400 DNA repair and recombination proteins [BR:cfa03400]
    403869 (TP53)
Transcription factors [BR:cfa03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   p53
    403869 (TP53)
Chromosome and associated proteins [BR:cfa03036]
 Eukaryotic type
  Sister chromatid separation proteins
   Aurora kinases
    Regulators of Aurora kinases
     403869 (TP53)
DNA repair and recombination proteins [BR:cfa03400]
 Eukaryotic type
  Check point factors
   Other check point factors
    403869 (TP53)
SSDB
Motif
Pfam: P53 P53_tetramer P53_TAD
Other DBs
NCBI-GeneID: 403869
NCBI-ProteinID: NP_001376147
Ensembl: ENSCAFG00000016714
VGNC: 47719
UniProt: A0A8C0RLV2
LinkDB
Position
5:complement(32699559..32713071)
AA seq 381 aa
MQEPQSELNIDPPLSQETFSELWNLLPENNVLSSELCPAVDELLLPESVVNWLDEDSDDA
PRMPATSAPTAPGPAPSWPLSSSVPSPKTYPGTYGFRLGFLHSGTAKSVTWTYSPLLNKL
FCQLAKTCPVQLWVSSPPPPNTCVRAMAIYKKSEFVTEVVRRCPHHERCSDSSDGLAPPQ
HLIRVEGNLRAKYLDDRNTFRHSVVVPYEPPEVGSDYTTIHYNYMCNSSCMGGMNRRPIL
TIITLEDSSGNVLGRNSFEVRVCACPGRDRRTEEENFHKKGEPCPEPPPGSTKRALPPST
SSSPPQKKKPLDGEYFTLQIRGRERYEMFRNLNEALELKDAQSGKEPGGSRAHSSHLKAK
KGQSTSRHKKLMFKREGPDSD
NT seq 1146 nt   +upstreamnt  +downstreamnt
atgcaagagccacagtcagagctcaatatcgacccccctctgagccaggagacattttca
gaattgtggaacctgcttcctgaaaacaatgttctgtcttcggagctgtgcccagcagtg
gatgagctgctgctcccagagagcgtcgtgaactggctagacgaagactcagatgatgct
cccaggatgccagccacttctgcccccacagcccctggaccggccccctcctggccccta
tcatcctctgtcccttccccgaagacctaccctggcacctatgggttccgtttggggttc
ctgcattccgggacagccaagtctgttacttggacgtactcccctctcctcaacaagttg
ttttgccagctggcgaagacctgccccgtgcagctgtgggtcagctccccacccccaccc
aatacctgcgtccgcgctatggccatctataagaagtcggagttcgtgaccgaggttgtg
cggcgctgcccccaccatgaacgctgctctgacagtagtgacggtcttgcccctcctcag
catctcatccgagtggaaggaaatttgcgggccaagtacctggacgacagaaacactttt
cgacacagtgtggtggtgccttatgagccacccgaggttggctctgactataccaccatc
cactacaactacatgtgtaacagttcctgcatgggaggcatgaaccggcggcccatcctc
actatcatcaccctggaagactccagtggaaacgtgctgggacgcaacagctttgaggta
cgcgtttgtgcctgtcccgggagagaccgccggactgaggaggagaatttccacaagaag
ggggagccttgtcctgagccaccccccgggagtaccaagcgagcactgcctcccagcacc
agctcctctcccccgcaaaagaagaagccactagatggagaatatttcacccttcagatc
cgtgggcgtgaacgctatgagatgttcaggaatctgaatgaagccttggagctgaaggat
gcccagagtggaaaggagccagggggaagcagggctcactccagccacctgaaggcaaag
aaggggcaatctacctctcgccataaaaaactgatgttcaagagagaagggcccgactca
gactga

DBGET integrated database retrieval system