KEGG   Canis lupus familiaris (dog): 403998
Entry
403998            CDS       T01007                                 
Symbol
TGFB1
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X1
  KO
K13375  transforming growth factor beta-1
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04010  MAPK signaling pathway
cfa04060  Cytokine-cytokine receptor interaction
cfa04068  FoxO signaling pathway
cfa04110  Cell cycle
cfa04148  Efferocytosis
cfa04218  Cellular senescence
cfa04350  TGF-beta signaling pathway
cfa04380  Osteoclast differentiation
cfa04390  Hippo signaling pathway
cfa04518  Integrin signaling
cfa04659  Th17 cell differentiation
cfa04672  Intestinal immune network for IgA production
cfa04926  Relaxin signaling pathway
cfa04932  Non-alcoholic fatty liver disease
cfa04933  AGE-RAGE signaling pathway in diabetic complications
cfa05140  Leishmaniasis
cfa05142  Chagas disease
cfa05144  Malaria
cfa05145  Toxoplasmosis
cfa05146  Amoebiasis
cfa05152  Tuberculosis
cfa05161  Hepatitis B
cfa05166  Human T-cell leukemia virus 1 infection
cfa05200  Pathways in cancer
cfa05205  Proteoglycans in cancer
cfa05210  Colorectal cancer
cfa05211  Renal cell carcinoma
cfa05212  Pancreatic cancer
cfa05220  Chronic myeloid leukemia
cfa05225  Hepatocellular carcinoma
cfa05226  Gastric cancer
cfa05321  Inflammatory bowel disease
cfa05323  Rheumatoid arthritis
cfa05410  Hypertrophic cardiomyopathy
cfa05414  Dilated cardiomyopathy
cfa05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    403998 (TGFB1)
   04350 TGF-beta signaling pathway
    403998 (TGFB1)
   04390 Hippo signaling pathway
    403998 (TGFB1)
   04068 FoxO signaling pathway
    403998 (TGFB1)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    403998 (TGFB1)
   04518 Integrin signaling
    403998 (TGFB1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    403998 (TGFB1)
  09143 Cell growth and death
   04110 Cell cycle
    403998 (TGFB1)
   04218 Cellular senescence
    403998 (TGFB1)
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    403998 (TGFB1)
   04672 Intestinal immune network for IgA production
    403998 (TGFB1)
  09152 Endocrine system
   04926 Relaxin signaling pathway
    403998 (TGFB1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    403998 (TGFB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    403998 (TGFB1)
   05205 Proteoglycans in cancer
    403998 (TGFB1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    403998 (TGFB1)
   05212 Pancreatic cancer
    403998 (TGFB1)
   05225 Hepatocellular carcinoma
    403998 (TGFB1)
   05226 Gastric cancer
    403998 (TGFB1)
   05220 Chronic myeloid leukemia
    403998 (TGFB1)
   05211 Renal cell carcinoma
    403998 (TGFB1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    403998 (TGFB1)
   05161 Hepatitis B
    403998 (TGFB1)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    403998 (TGFB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    403998 (TGFB1)
   05144 Malaria
    403998 (TGFB1)
   05145 Toxoplasmosis
    403998 (TGFB1)
   05140 Leishmaniasis
    403998 (TGFB1)
   05142 Chagas disease
    403998 (TGFB1)
  09163 Immune disease
   05323 Rheumatoid arthritis
    403998 (TGFB1)
   05321 Inflammatory bowel disease
    403998 (TGFB1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    403998 (TGFB1)
   05414 Dilated cardiomyopathy
    403998 (TGFB1)
   05415 Diabetic cardiomyopathy
    403998 (TGFB1)
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    403998 (TGFB1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    403998 (TGFB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:cfa03110]
    403998 (TGFB1)
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:cfa04052]
    403998 (TGFB1)
   00536 Glycosaminoglycan binding proteins [BR:cfa00536]
    403998 (TGFB1)
Chaperones and folding catalysts [BR:cfa03110]
 Intramolecular chaperones
  Others
   403998 (TGFB1)
Cytokines and neuropeptides [BR:cfa04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   403998 (TGFB1)
Glycosaminoglycan binding proteins [BR:cfa00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   403998 (TGFB1)
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 403998
NCBI-ProteinID: XP_038300925
Ensembl: ENSCAFG00000005014
LinkDB
Position
1
AA seq 391 aa
MPPSGLRLLPLLLPLLRLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVENTNKI
YEKVKKSPHSIYMLFNTSELREAVPEPVLLSRAELRLLRLKLKAEQHVELYQKYSNDSWR
YLSNRLLAPSDTPEWLSFDVTGVVRQWLSHGGEVEGFRLSAHCSCDSKDNTLQVDINAGF
SSSRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRQRRALDTNYCFSSTEKNCCVRQLY
IDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQ
ALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgccgccctccgggctgcggctgctgccgctgctgctgccgctgctgcggctactagtg
ctgacgcctggccggccggccgccggactgtccacctgcaagaccatcgacatggaactg
gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgcc
agccccccgagccagggggaggtgccgcccgggccgctgcccgaggccgtgctggccctc
tacaacagcacccgcgaccgggtggcgggggagagcgccgagccggagcccgagcccgag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaacaccaacaaaatc
tatgagaaagtcaagaaaagtccgcacagcatatatatgctcttcaacacatcagagctc
cgagaagcagtgcctgagcccgtcttgctctcccgggcagagttgcgcctgctgaggctc
aagttaaaagcggagcagcatgtggagctgtaccagaaatatagcaatgattcctggcgc
tacctcagcaaccggctgctggcgcccagcgacacgccagaatggctgtcctttgatgtc
actggagtcgtgaggcagtggctgagccatggaggggaagtcgagggctttcgcctcagt
gcccactgttcctgtgacagcaaagataacacactgcaagtagacattaacgcagggttc
agttccagccgccgaggtgacctggccaccattcatggcatgaaccgacccttcctgctc
ctcatggccaccccactggagagggcccagcacctgcacagctcccggcagcgccgggcc
ctggacaccaactactgcttcagctccacggagaagaactgctgcgtccggcagctctac
attgacttccgcaaggatctgggctggaagtggatccatgagcccaagggttaccacgct
aacttctgcctggggccctgcccctacatttggagcctggacacgcagtacagcaaggtc
ctggccctgtacaaccagcacaacccgggcgcgtcggcggcgccgtgctgcgtgccgcag
gcgctggagccactgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctg
tcgaacatgatcgtgcgctcctgcaagtgcagctga

DBGET integrated database retrieval system