Canis lupus familiaris (dog): 415128 Help Entry 415128            CDS       T01007                                  Symbol CYP2E1 Name (RefSeq) cytochrome P450 2E1   KO K07415   cytochrome P450 family 2 subfamily E1 [EC:1.14.14.-] Organism cfa  Canis lupus familiaris (dog) Pathway cfa00140   Steroid hormone biosynthesis cfa00590   Arachidonic acid metabolism cfa00591   Linoleic acid metabolism cfa00980   Metabolism of xenobiotics by cytochrome P450 cfa00982   Drug metabolism - cytochrome P450 cfa00983   Drug metabolism - other enzymes cfa01100   Metabolic pathways cfa04932   Non-alcoholic fatty liver disease cfa04936   Alcoholic liver disease cfa05204   Chemical carcinogenesis - DNA adducts cfa05208   Chemical carcinogenesis - reactive oxygen species Brite KEGG Orthology (KO) [BR:cfa00001]  09100 Metabolism   09103 Lipid metabolism    00140 Steroid hormone biosynthesis     415128 (CYP2E1)    00590 Arachidonic acid metabolism     415128 (CYP2E1)    00591 Linoleic acid metabolism     415128 (CYP2E1)   09111 Xenobiotics biodegradation and metabolism    00980 Metabolism of xenobiotics by cytochrome P450     415128 (CYP2E1)    00982 Drug metabolism - cytochrome P450     415128 (CYP2E1)    00983 Drug metabolism - other enzymes     415128 (CYP2E1)  09160 Human Diseases   09161 Cancer: overview    05204 Chemical carcinogenesis - DNA adducts     415128 (CYP2E1)    05208 Chemical carcinogenesis - reactive oxygen species     415128 (CYP2E1)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     415128 (CYP2E1)    04932 Non-alcoholic fatty liver disease     415128 (CYP2E1)  09180 Brite Hierarchies   09181 Protein families: metabolism    00199 Cytochrome P450 [BR:cfa00199]     415128 (CYP2E1) Cytochrome P450 [BR:cfa00199]  Cytochrome P450, animal type   CYP2 family    415128 (CYP2E1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  p450 DUF6361 Motif Other DBs NCBI-GeneID:  415128 NCBI-ProteinID:  NP_001003339 Ensembl:  ENSCAFG00000013311 VGNC:  50353 UniProt:  Q9MZY0 LinkDB All DBs Position 28:41171673..41181706 Genome browser AA seq 494 aa AA seqDB search MAALGITVALLVWMATLMLISIWKQIYSRWKLPPGPFPLPIIGNILQVDIKNVPKSLAKL AEQYGPVFTLYLGSQRTVVLHGYKAVKEVLLDHKNDLSGRGEVFAFQSHKDRGITFNNGP GWKDTRRLSLSTLRDYGMGKRGNEERIQREIPFLLEALRGTRGQPFDPTFLLGFAPFNVI ADILFHKHFDYSDQTGLRIQKLFNENFHLLSTGWLQLYNIFPSYLHYLPGSHRKVLRNVA ELKDYSLERVKEHQESLDPTCSRDFTDCLLQELQKERYGTEPWYTLDNIAVTVADLFFAG TETTSTTLRYGLLILMKYPEVEEKLHEEIDRVIGPSRVPAIKDRLEMPYMDAVVHEIQRF IDLLPSNLPHVANQDTMFRGYVIPKGTVVIPTLDSVLFDKQEFPDPEKFKPEHFLNENGK FKYSDYFKAFSAGKRVCVGEGLARMELFLFLSAILQHFNLKSLVDPKDIDLSPCTIGFAK IPPHYKLCVVPRSG NT seq 1485 nt NT seq  +upstreamnt  +downstreamnt atggccgccttgggcatcacagtggccctgctggtgtggatggccaccttaatgcttatc tctatctggaagcagatctacagccgctggaaactgccccctggcccttttccactgccc atcattgggaatattctgcaggtggatatcaagaatgttcccaaatctctcgccaagctg gcagagcagtacgggccagtgttcaccttgtacctgggctcccagcgcacagtggtcctg catggctacaaggcggtgaaggaagttctgcttgaccacaagaatgacctttctggcaga ggagaagtcttcgcattccagtcgcacaaggacagagggatcacgttcaacaatgggccc ggctggaaggacacgcggcgactctccctgagcaccctccgggactacggcatggggaag cgcggcaacgaggagcggatccagagggagatccccttcctgctggaggcgctcaggggc acccggggccagcccttcgaccccacctttctcctgggcttcgcccccttcaacgtcatc gctgacatcctcttccacaagcactttgactactcggatcagactgggctgcggatacag aagctgttcaacgagaacttccacctgctcagcaccggctggctccagctttataacatt ttcccaagctatctgcactacctgcccggaagccatagaaaagtcttaagaaatgtggct gaactaaaggattacagcttagaaagggtgaaggagcaccaggagtcgctggaccccacc tgctcccgggacttcactgactgcttgctccaggagctgcagaaggagagatacggtacg gagccttggtataccttggacaacattgccgtgaccgtggctgacctgttctttgcgggc acggagaccaccagcaccaccctgagatacgggctcctgattctcatgaaatacccagag gtcgaagagaaacttcatgaagaaatcgacagggtgatcggcccaagccgagtccctgcc atcaaggacaggctggagatgccctacatggatgccgtggtgcacgagattcagcgattc atcgacctgctgccctccaacctgccccatgtagcaaaccaggacacgatgttcagagga tatgtcatccccaagggcacagtggtaattcccacactggactccgtcttgtttgacaaa caagaattccctgatccagagaagttcaagccagagcactttctgaatgaaaacggaaaa ttcaaatatagtgactacttcaaggcattctccgcaggaaagcgggtgtgtgttggagaa ggcctggctcgcatggagctcttcctgttcttgtccgccattttgcagcactttaacctg aagtctctcgtcgaccccaaggatattgacctcagtccctgcacaatcgggtttgccaag atccccccccattacaaactctgtgtcgttccccgctcgggctga

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