Canis lupus familiaris (dog): 474630
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Entry
474630 CDS
T01007
Symbol
HSD17B4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2 isoform X1
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa00120
Primary bile acid biosynthesis
cfa01040
Biosynthesis of unsaturated fatty acids
cfa01100
Metabolic pathways
cfa01212
Fatty acid metabolism
cfa04146
Peroxisome
Module
cfa_M00861
beta-Oxidation, peroxisome, VLCFA
cfa_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
474630 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
474630 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
474630 (HSD17B4)
Enzymes [BR:
cfa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
474630 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
474630 (HSD17B4)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
MFE-2_hydrat-2_N
MaoC_dehydratas
adh_short
adh_short_C2
SCP2
KR
Alkyl_sulf_C
FAS1_DH_region
AbrB-like
Motif
Other DBs
NCBI-GeneID:
474630
NCBI-ProteinID:
XP_005626402
Ensembl:
ENSCAFG00000000158
VGNC:
41807
UniProt:
A0A8C0RXL9
A0A8I3N3X9
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All DBs
Position
11:9845728..9939173
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AA seq
762 aa
AA seq
DB search
MTFQTIRTGSLGELLRLRMLLELLQPLDNQGRREWKLPVGALSRGLGRAYALAFAERGAS
VVVNDLGGDFKGLGKGSFAAADKVVEEIRSKGGKAVANYDSVEAGEKIVRTALEAFGRID
VVVNNAGILRDSSFGRISDEDWDIIHRVHLRGSFQVTRAAWNHMKKQKFGRIVMTSSASG
IYGNFGQASYSAAKLGLLGFSNTLAIEGKTSNIHCNTIAPTAGSRMTQTVMAEDLLKALK
PDYVAPLVLWLCHESCEENGSLFEVGGGWIGKLRWERTLGAIVRQKNQPVTPEAVKANWK
KICDFDNATKPQSIQESVASLIGVVNTIDSDGGVSTNHTSHAASTATSEFAGAIGHKFPP
FSSAYTELETIMYALGVGASVKEPKDMKFIYEGSTDFSCLPTFGVIIAQKFVIGGGLSEI
PGFSVNLAKVLHGEQYLELYKPLPRAGNLRCEAVVADVLDKGSGSVILVDVYSYFEEELI
CYNQFSLFLVGSGGTGGKRTSDKVKATVAVPNRPPDAVLTDTTSLNQAALYRLSGDWNPL
HIDPNFAGFAGFDKPILHGLCTFGFSARHVLQKFADNDVSRFKAIKVRFAKPVYPGQTLQ
TEMWKEGNRIHFQTKIQETGDIVISNAYVDLMPTSDTSAQTPSEGGELQSTLVFEEIGRR
LKDIGHEVAKKVNAVFEWHITKGGNIAAKWTIDLKSGFGKVYQGPAKGPADATFTLSDED
FMDVVLGKLDPQKAFFSGRLKARGNIMLSQKLQMILKDYAKL
NT seq
2289 nt
NT seq
+upstream
nt +downstream
nt
atgacttttcaaacaatcagaactggttcattaggggagctgctacgtctgaggatgctg
ttggaactgctacagccactggataaccaagggcgtagagaatggaagctgccagttgga
gctctatcgagaggactgggccgagcctatgccctggcatttgcagaaagaggtgcatct
gttgttgtgaatgatttaggaggagactttaagggattgggtaaaggctcctttgcagct
gccgataaggttgttgaagaaatacgaagtaaaggcggaaaagctgtggccaactatgat
tcagtggaagcaggagagaagattgtacggacagcactagaagcttttggaagaatagat
gttgtggtcaacaatgctggaattctgagggacagttcttttggtagaataagcgatgaa
gattgggatataatccacagagtccatttgcgaggctcattccaagtgacccgggcagct
tggaatcatatgaagaaacaaaagtttggaaggattgttatgacttcatcagcttcagga
atatatggaaactttggccaggccagttacagtgctgcaaagctgggtcttctgggcttt
tcaaatacccttgcaattgaaggcaagacaagcaacattcattgtaacaccattgctcct
actgctggatcacggatgacccaaaccgttatggctgaagatctcttgaaagctctgaag
ccagattacgtggcccccctggtcctttggctttgccacgagagctgtgaggaaaatggt
agcttgtttgaggttggaggaggatggattggaaaactacgctgggagcggacccttggg
gccattgtgaggcagaagaatcagccagtgactccggaggcagtgaaggccaactggaag
aagatctgtgactttgacaatgccaccaagccgcagagtattcaagaatcagttgccagt
ttaattggagttgtaaatacaatagattcggatggaggagtttcaacaaatcatacgagt
catgcagcatcaacagctacatcagagtttgctggagccattggccataaatttcctcca
ttttcttctgcttacacggaactggaaactattatgtatgccctaggcgtgggggcatcg
gtcaaggaacccaaagatatgaaatttatatatgaaggaagcaccgatttctcctgtttg
cctacctttggagttataatagctcagaaatttgtaataggtggaggattatcagagatt
cctgggttttcagtcaacttggcaaaggttctccatggggagcaatacttggagttatat
aaaccacttcccagagcaggaaacttaagatgtgaagcagttgttgctgatgtcctagat
aaaggatccggttcagtaattcttgtggatgtctattcttattttgaggaggaacttata
tgttataatcagttctctcttttccttgttggctctggaggtactggtggaaaacggaca
tcagacaaagtcaaggcaactgtagctgtgcctaataggcctcctgatgctgttcttaca
gataccacctcactcaatcaggctgctttgtaccgcctcagtggtgactggaatccctta
cacattgatcccaactttgctggtttcgcaggttttgacaagcccatattacatggattg
tgtacatttggattttctgccaggcatgttttacagaaatttgcagataacgatgtatcg
agattcaaagcaattaaggttcgttttgcaaaaccagtatatccgggacagactcttcaa
actgagatgtggaaggaaggaaatagaatccatttccaaaccaagatccaagaaactgga
gatattgtcatttcaaatgcatatgtggatctcatgccaacatctgatacttcagctcag
acaccctctgagggtggagagctccagagtaccctggtatttgaggagataggtcgccgc
cttaaggatattgggcatgaagtggcaaagaaagtaaatgccgtatttgagtggcatatc
actaaaggtggaaacatcgcagccaagtggactattgacctaaaaagtggttttggaaaa
gtgtatcaaggtcctgccaaaggccctgctgatgcaaccttcacactttcagatgaagat
ttcatggatgtggtcttgggcaagcttgaccctcagaaggcattctttagtggcagactg
aaggccagagggaatatcatgctgagccagaagcttcagatgattcttaaagactatgcc
aagctctaa
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