KEGG   Canis lupus familiaris (dog): 475108
Entry
475108            CDS       T01007                                 
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X14
  KO
K05725  focal adhesion kinase 1 [EC:2.7.10.2]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa01522  Endocrine resistance
cfa04012  ErbB signaling pathway
cfa04062  Chemokine signaling pathway
cfa04148  Efferocytosis
cfa04151  PI3K-Akt signaling pathway
cfa04360  Axon guidance
cfa04370  VEGF signaling pathway
cfa04510  Focal adhesion
cfa04670  Leukocyte transendothelial migration
cfa04810  Regulation of actin cytoskeleton
cfa04935  Growth hormone synthesis, secretion and action
cfa05100  Bacterial invasion of epithelial cells
cfa05135  Yersinia infection
cfa05146  Amoebiasis
cfa05163  Human cytomegalovirus infection
cfa05165  Human papillomavirus infection
cfa05170  Human immunodeficiency virus 1 infection
cfa05200  Pathways in cancer
cfa05202  Transcriptional misregulation in cancer
cfa05205  Proteoglycans in cancer
cfa05208  Chemical carcinogenesis - reactive oxygen species
cfa05222  Small cell lung cancer
cfa05417  Lipid and atherosclerosis
cfa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    475108 (PTK2)
   04370 VEGF signaling pathway
    475108 (PTK2)
   04151 PI3K-Akt signaling pathway
    475108 (PTK2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    475108 (PTK2)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    475108 (PTK2)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    475108 (PTK2)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    475108 (PTK2)
   04062 Chemokine signaling pathway
    475108 (PTK2)
  09152 Endocrine system
   04935 Growth hormone synthesis, secretion and action
    475108 (PTK2)
  09158 Development and regeneration
   04360 Axon guidance
    475108 (PTK2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    475108 (PTK2)
   05202 Transcriptional misregulation in cancer
    475108 (PTK2)
   05205 Proteoglycans in cancer
    475108 (PTK2)
   05208 Chemical carcinogenesis - reactive oxygen species
    475108 (PTK2)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    475108 (PTK2)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    475108 (PTK2)
   05163 Human cytomegalovirus infection
    475108 (PTK2)
   05165 Human papillomavirus infection
    475108 (PTK2)
  09171 Infectious disease: bacterial
   05135 Yersinia infection
    475108 (PTK2)
   05100 Bacterial invasion of epithelial cells
    475108 (PTK2)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    475108 (PTK2)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    475108 (PTK2)
   05418 Fluid shear stress and atherosclerosis
    475108 (PTK2)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    475108 (PTK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    475108 (PTK2)
   01009 Protein phosphatases and associated proteins [BR:cfa01009]
    475108 (PTK2)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     475108 (PTK2)
Protein kinases [BR:cfa01001]
 Non-receptor tyrosine kinases
  FAK family
   475108 (PTK2)
Protein phosphatases and associated proteins [BR:cfa01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     475108 (PTK2)
SSDB
Motif
Pfam: Focal_AT GIT1_C
Other DBs
NCBI-GeneID: 475108
NCBI-ProteinID: XP_022282477
Ensembl: ENSCAFG00000001217
VGNC: 45158
LinkDB
Position
13:complement(35161620..35427478)
AA seq 365 aa
MRMESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPAS
HGIPAMAGSIYPGQASLLDQTDSWNHRPQEISMWQPNMEDSAALDLRGIGQVLPTHLMEE
RLIRQQQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPTGNQHIYQPVGKPDPA
APPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEISPPPTANLDRSNDRVYEN
VTGLVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLPVLPASTHREIEMAQ
KLLNSDLGELINKMKLAQQYVMTSLQQEYKKQMLTAAHALAVDAKNLLDVIDQARLRMLG
PTRPH
NT seq 1098 nt   +upstreamnt  +downstreamnt
atgaggatggagtccagaagacaggtcacagtatcctgggactccggagggtccgacgaa
gctccacccaagcccagcagacccggttaccctagtccaaggtccagcgaaggattttat
cccagtccacagcacatggtacaaaccaatcattaccaggtctctggctatcctgcttca
catgggatcccagccatggccggcagcatctacccaggtcaggcatctcttttggaccag
acggattcatggaatcatagaccacaggagatatcaatgtggcagcccaacatggaggac
tctgctgcgctggacctgcgagggattgggcaggtattgccgacccacctaatggaagag
cggctaatccggcagcagcaggaaatggaagaagatcagcgctggctggaaaaagaggag
agatttctgaaacctgatgtgcggctctctcgaggcagcattgacagggaggatggaagt
ctccagggcccgactggaaaccaacacatataccagcctgtgggtaaaccagatcctgca
gctccgccaaagaaaccgccacggcctggagcccctggtcacctgggcagcctcgccagc
ctcagcagccccggggacagttacaatgagggcgtcaagccatggaggcttcagccccag
gaaatcagccccccgcccactgccaacctggaccggtccaacgacagggtgtacgagaat
gtgacgggcctggtgaaggctgtcatcgaaatgtccagcaagatccagccagccccaccg
gaggagtatgttcccatggtgaaggaagtcggcctggccctgcggacgttactggccact
gtggacgagacccttccggtcctgccggccagcacgcaccgagagattgagatggcccag
aagctgttgaactccgacctgggtgagctcatcaacaagatgaagctggcccagcagtac
gtcatgaccagtctccagcaggagtacaaaaagcagatgctgaccgctgctcatgccttg
gccgtggatgccaaaaacttactcgatgtcattgaccaagcgagactgcggatgctcgga
ccaacgaggccacactga

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