Canis lupus familiaris (dog): 475756
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Entry
475756 CDS
T01007
Symbol
EIF2AK3
Name
(RefSeq) eukaryotic translation initiation factor 2-alpha kinase 3 isoform X2
KO
K08860
eukaryotic translation initiation factor 2-alpha kinase 3 [EC:
2.7.11.1
]
Organism
cfa
Canis lupus familiaris (dog)
Pathway
cfa04137
Mitophagy - animal
cfa04140
Autophagy - animal
cfa04141
Protein processing in endoplasmic reticulum
cfa04156
Integrated stress response (ISR) signaling pathway
cfa04210
Apoptosis
cfa04932
Non-alcoholic fatty liver disease
cfa05010
Alzheimer disease
cfa05012
Parkinson disease
cfa05014
Amyotrophic lateral sclerosis
cfa05020
Prion disease
cfa05022
Pathways of neurodegeneration - multiple diseases
cfa05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
cfa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
475756 (EIF2AK3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
475756 (EIF2AK3)
04137 Mitophagy - animal
475756 (EIF2AK3)
09143 Cell growth and death
04210 Apoptosis
475756 (EIF2AK3)
04156 Integrated stress response (ISR) signaling pathway
475756 (EIF2AK3)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
475756 (EIF2AK3)
05012 Parkinson disease
475756 (EIF2AK3)
05014 Amyotrophic lateral sclerosis
475756 (EIF2AK3)
05020 Prion disease
475756 (EIF2AK3)
05022 Pathways of neurodegeneration - multiple diseases
475756 (EIF2AK3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
475756 (EIF2AK3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
475756 (EIF2AK3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
cfa01001
]
475756 (EIF2AK3)
09182 Protein families: genetic information processing
03012 Translation factors [BR:
cfa03012
]
475756 (EIF2AK3)
Enzymes [BR:
cfa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
475756 (EIF2AK3)
Protein kinases [BR:
cfa01001
]
Serine/threonine kinases: Other
PEK family [OT]
475756 (EIF2AK3)
Translation factors [BR:
cfa03012
]
Eukaryotic type
Initiation factors
Initiation associated factors
475756 (EIF2AK3)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
Kdo
ABC1
PQQ_2
DUF7670
Motif
Other DBs
NCBI-GeneID:
475756
NCBI-ProteinID:
XP_005630515
Ensembl:
ENSCAFG00000007383
VGNC:
40258
LinkDB
All DBs
Position
17
Genome browser
AA seq
963 aa
AA seq
DB search
MIIPSLDGDLFQWDRDRESMETVPFTVESLLESSYKFGDDVVLVGGKSLTTYGLSAYSGK
VRYICSALGCRQWDNDDIEQEDILLLQRSQKTVRAVGPRSGNEKWNFSVGHFELRYIPDM
ETRAGFIESTLKPSGNKEGSKIISDVEEQEAAMLDTVIKVSVADWKVMAFSKKGGQLEWE
YQFCTPIASAWLVKDGKVIPISLFDDTSYASNDEVLEDEEDIVEAARGATESSVYLGMYR
GQLYLQSSVRISEKFPTSPKALESVNNEYAIMPLPTIKWKPLIHSPSRTPVLVGSDEFDK
CLSNDKFSHEEYSNGALSILQYPYDNGYYLPYYKRERSKRSTHITVRFLDNPNYNKNIRK
KDPVLLLHWWKEIVGTILFCIIATTFIVRRLFHPHPHRQRKESETQCQTESKYDSVSGEA
KDSSWNDIKNSGYVSRYLTDFEPVQCMGRGGFGVVFEAKNKVDDCNYAIKRIRLPNRELA
REKVMREVKALAKLDHPGIVRYFNAWLEAPPEKWQEKMDEIWLKDESTDWPLSSPSPMDA
PSVKIRRMDPFSTKEHIEIIAPSSQRRSFSVGISCGQTSSSESQFSPLEFSGTDHGDTSE
SVDAACNLQDSCVTDCDIEDGTLDGNVEGHSSELCPAGASPYERSRERTSSSIVFEDSGC
DNASSKEELKTKRLNIGNHCANKQTAFKHSSSKSSSEPTFSVSPPRPTTLSLDLSKNTAE
KLQPSSPKVYLYIQMQLCRKENLKDWMNSRCTIEERERSVCLHIFLQIAEAVEFLHSKGL
MHRDLKPSNIFFTVDDVVKVGDFGLVTAMDQDEEEQTVLTPMPAYARHTGQVGTKLYMSP
EQIHGNNYSHKVDIFSLGLILFELLYPFGTQMERVRVLTDVRNLKFPPLFTQKYPREHVM
VQDMLSPSPMERPEATNIIENAVFEDLELPGKTVLRQRSRSMSSSGTKHSRQSSNSRSPL
PSN
NT seq
2892 nt
NT seq
+upstream
nt +downstream
nt
atgatcattccttccctggatggagacctcttccagtgggaccgggaccgtgagagcatg
gaaacagttccttttacagttgaatcacttcttgaatcttcttataaatttggagatgat
gttgttttggttggcggaaagtctctcactacatatggactcagtgcatatagtggcaag
gtgaggtacatctgttcagctttgggttgtcgccagtgggataacgatgacatagaacaa
gaagacatcctgcttctgcaacgctcccagaaaaccgttagagctgtaggacctcgcagt
ggcaatgagaagtggaatttcagtgttggccactttgaacttcggtatattccagacatg
gaaactagagctggatttattgaaagcaccttaaagcccagtgggaacaaagaagggtct
aaaattatttcagatgtggaagaacaggaagctgccatgttggacacagtgataaaggtc
tcagttgctgactggaaggttatggcgttcagtaagaaaggaggacagctggaatgggaa
taccagttttgtactcccattgcatctgcttggttggttaaagatggaaaagtcattccc
atcagtctttttgatgatacaagttacgcatctaacgatgaagttttagaagatgaagaa
gacattgtagaagctgctcgaggagccacagaaagcagtgtttacctgggaatgtacaga
ggtcagctgtatctccagtcatcagtcagaatttcagaaaagtttcctacaagtcccaag
gctttggaatctgtcaataatgaatatgcaattatgcctttgccaaccatcaagtggaaa
cccttaattcattctccttccagaactcctgtcttggtagggtctgacgaatttgacaaa
tgtcttagtaatgataagttctctcacgaagagtacagtaatggtgcactttcaatcttg
caatacccatatgataatggttattatctaccatactacaagagggagagaagcaaacgg
agcacacatatcacagtccgatttcttgataacccaaattacaacaagaacattcgcaaa
aaggatcctgttctcctcttacactggtggaaagaaatagttggaactattctgttttgt
atcatagcaacaacttttattgtccgtagacttttccatcctcatcctcacagacaaagg
aaggaatctgaaactcagtgtcaaactgaaagtaaatatgattctgtaagtggagaagct
aaggacagcagctggaatgacataaaaaattctggatatgtatcacgctatctgacagat
tttgaaccagttcagtgtatgggtcgtggcgggtttggagtagtcttcgaagccaaaaac
aaagtagatgactgcaattatgctatcaagagaatccgcctccccaacagagagttggct
cgggaaaaggtaatgcgagaagttaaagccttagccaagcttgaccatccagggattgtt
agatatttcaatgcttggttagaagcaccaccagagaagtggcaagaaaaaatggatgaa
atttggttaaaagatgaaagcacagactggccactcagctctcctagtccaatggacgca
ccatcagttaaaatacgcagaatggatcctttctctacaaaggaacatattgaaatcata
gctccttcttcacaaaggaggtctttttcagtagggatttcctgtggccagacaagttcc
tctgaaagccagttctctccactggaattttctggaacagaccatggagataccagtgag
tcagtggatgcagcatgcaacctccaggacagctgtgtcacggactgtgatatagaagat
ggtactctggacggcaatgtcgaagggcactcctctgaactttgtcctgctggagcttct
ccttatgaaagatcaagggagagaacatcctcttccatagtgtttgaagattccggctgt
gataacgcatccagcaaagaagagctcaaaactaagcgactgaatattggcaaccattgt
gctaataaacaaactgctttcaagcattccagtagcaaatcttcttctgaacctactttc
tctgtttctcctccaagaccgaccactttaagtttagatctcagcaaaaacactgcagaa
aaactccagcccagttccccgaaggtatatctttacatccagatgcagctctgcagaaag
gaaaacctcaaagactggatgaacagccggtgtaccatagaggagcgagagaggagcgtg
tgtctgcacatcttcctacagatcgcagaggcagtagagtttttgcacagcaaagggctc
atgcacagggatctcaagccttccaatatattctttacagtggatgatgtggtcaaggtt
ggagactttggattagtgactgcaatggaccaggatgaagaagagcagacggttctgacc
ccaatgccagcgtatgccagacatacaggacaagtggggaccaaactgtatatgagccca
gaacagattcatgggaacaactactctcataaagtggacatcttttctttaggcctcatt
ctgtttgaattgctgtacccattcggcactcagatggagagagtcagggtcttaactgat
gtaagaaatctcaaatttccgccactatttactcagaaatatcctcgtgagcatgtgatg
gttcaagacatgctttctccatcccccatggaacggcctgaagccaccaacatcattgaa
aatgctgtatttgaagacttggagcttccgggaaaaacagttctcagacagaggtctcgc
tccatgagctcatcaggaacaaagcattcaagacagtccagcaactcccggagccctttg
ccaagcaactag
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